Patents Assigned to The University of Tokyo
-
Publication number: 20220360067Abstract: A current interrupting device includes: a current limiting element provided on a power supply path from a predetermined power supply to a load device, the current limiting element being configured to exhibit a current limiting action when current flowing the power supply path exceeds a first current threshold value; a current diversion path switch capable of switching on and off of an electric conduction of a current diversion path, the current diversion path switch being connected in parallel with the power supply path; and a controller configured to control on and off of the current diversion path switch, wherein, the controller is configured to: switch the current diversion path switch on from an off state when it is detected that current flowing the current limiting element is limited to a second current threshold value after the current flowing the current limiting element has exceeded the first current threshold value; and switch the current diversion path switch off again after a predetermined switchedType: ApplicationFiled: September 15, 2020Publication date: November 10, 2022Applicants: National University Corporation Saitama University, TOKYO INSTITUTE OF TECHNOLOGY, The University of TokyoInventors: Yuki INADA, Yasushi YAMANO, Mitsuaki MAEYAMA, Shungo ZEN, Wataru OHNISHI
-
Patent number: 11491507Abstract: An object is to suppress a variation in amount of a sealant that is applied on an object to be sealed. There is provided a sealant discharge nozzle configured such that a sealant from a cartridge is discharged from a discharge hole of the sealant discharge nozzle. The sealant discharge nozzle has a leading end portion comprising a pair of side wall portions; and a connecting wall portion configured to connect the pair of side wall portions with each other and provided in cooperation with the pair of side wall portions to form a first recess that is open on one side in a first direction perpendicular to an axial direction of the sealant discharge nozzle, and on a leading end side. The discharge hole has an opening formed on a first recess side of the connecting wall portion.Type: GrantFiled: June 19, 2020Date of Patent: November 8, 2022Assignee: THE UNIVERSITY OF TOKYOInventors: Masayoshi Okamoto, Tadamichi Mawatari, Kensuke Tsuchiya, Masayoshi Zaitsu, Naohiro Otsuki, Junji Tsuchiya, Youhei Matsumoto
-
Patent number: 11494383Abstract: When a DBMS receives a suspend instruction in which a suspend completion time of query processing is a future time and between receipt of the suspend instruction and the suspend completion time, if there is a target object (at least a processing object whose execution is in progress upon receipt of the suspend instruction) whose predicted completion time is at or precedes the suspend completion time, the DBMS changes the state of the target object to a state signifying a snapshot suspend. If there is a processing object whose state signifies a snapshot suspend, the DBMS executes the processing object at or before the suspend completion time.Type: GrantFiled: September 20, 2019Date of Patent: November 8, 2022Assignees: HITACHI, LTD., THE UNIVERSITY OF TOKYOInventors: Akira Shimizu, Kouji Kimura, Kazuhiko Mogi, Masaru Kitsuregawa, Kazuo Goda, Yuto Hayamizu
-
Patent number: 11491666Abstract: A control system according to an embodiment includes a motor configured to drive a link, a first sensor configured to detect information about the driving by the motor or information about a relation between the driving means and the load member as first sensor information, a second sensor configured to detect information about a displacement of the link as second sensor information, and a control unit configured to perform feedback control of the driving means so as to follow a command value in a two-inertial system model including an inertial system on a load side and an inertial system on a driving side. The control unit includes a disturbance observer configured to estimate a disturbance, and a filter configured to convert an estimated value of the disturbance into a driving force of the motor.Type: GrantFiled: October 17, 2019Date of Patent: November 8, 2022Assignees: THE UNIVERSITY OF TOKYO, TOYOTA JIDOSHA KABUSHIKI KAISHAInventors: Hiroshi Fujimoto, Akiyuki Hasegawa, Taro Takahashi
-
Patent number: 11491343Abstract: A coil apparatus for use in a transcranial magnetic stimulation apparatus is provided to further increase an electric field intensity on a head surface. The coil apparatus includes a wound-wire coil disposed on or near a head surface so as to generate a current by an induced electric field through electromagnetic induction in a magnetic stimulation-target region of a brain for stimulating neurons. The wound-wire coil includes a near-head-surface conductive wire portion disposed on or near the head surface, and a far-head-surface conductive wire portion disposed farther from the head surface than the near-head-surface conductive wire portion. A distance between the near-head-surface conductive wire portion and the far-head-surface conductive wire portion is set to be changed so that an intensity of the induced electric field becomes larger than that of a surrounding region of the magnetic stimulation-target region.Type: GrantFiled: April 7, 2020Date of Patent: November 8, 2022Assignees: THE UNIVERSITY OF TOKYO, OSAKA UNIVERSITYInventors: Youichi Saitoh, Masaki Sekino, Keita Yamamoto
-
Publication number: 20220348681Abstract: [Object] To provide a fusion protein of an antibody that recognizes cancer cells and a mutant streptavidin, which is for use in the treatment or diagnosis of cancer. [Means for Solution] A fusion protein comprising a protein-recognizing substance and the amino acid sequence as set forth in SEQ ID NO: 19 that is fused with the protein-recognizing substance.Type: ApplicationFiled: April 22, 2021Publication date: November 3, 2022Applicants: THE UNIVERSITY OF TOKYO, SAVID THERAPEUTICS INC.Inventors: Toshiya TANAKA, Tatsuhiko KODAMA, Takefumi YAMASHITA, Motomu KANAI, Kenzo YAMATSUGU, Toshifumi TATSUMI, Takeshi KAWAMURA, Akira SUGIYAMA, Masanobu TSUKAGOSHI, Yuzo TODA, Junji NISHIGAKI
-
Patent number: 11489460Abstract: The vibration-driven energy harvester includes: a first electrode; a second electrode facing the first electrode; a holder holding the first electrode and the second electrode so as to be movable relative to each other; a half-wave rectifier electrically connected to the first and the second electrodes that causes current flowing from the first electrode to the second electrode to flow to an output unit, and cuts off current flowing from the second electrode toward the first electrode; and a second rectifying element electrically connected to the first and the second electrodes that allows the current flowing from the second electrode to the first electrode and blocks the current flowing from the first electrode to the second electrode, wherein: the first electrode has a positively charged electret in a surface facing the second electrode, or the second electrode has a negatively charged electret in a surface facing the first electrode.Type: GrantFiled: April 25, 2019Date of Patent: November 1, 2022Assignees: The University of Tokyo, Saginomiya Seisakusho, Inc.Inventors: Hiroshi Toshiyoshi, Hisayuki Ashizawa, Masahiro Morita
-
Patent number: 11488060Abstract: Provided is a learning method, a learning program, a learning device, and a learning system, for training a classification model, to further raise the correct answer rate of classification by the classification model. The learning method includes execution of generating one piece of composite data by compositing a plurality of pieces of training data of which classification has each been set, or a plurality of pieces of converted data obtained by converting the plurality of pieces of training data, at a predetermined ratio, inputting one or a plurality of pieces of the composite data into the classification model, and updating a parameter of the classification model so that classification of the plurality of pieces of training data included in the composite data is replicated at the predetermined ratio by output of the classification model, by a computer provided with at least one hardware processor and at least one memory.Type: GrantFiled: July 25, 2018Date of Patent: November 1, 2022Assignee: The University of TokyoInventors: Tatsuya Harada, Yuji Tokozume
-
Patent number: 11478405Abstract: Provided is a cell preserving vessel which is protected against damage during storage. The cell preserving vessel 1 includes: a vessel body 10 which is made of a flexible resin member and has a cell accommodating part 11; a cell introducing tube 20 which is connected to the vessel body 10 and through which cells are introduced into the cell accommodating part 11; and a pair of tube protecting parts 40 which are arranged to hold the cell introducing tube 20 therebetween and which protect a vicinity of a joined portion of the cell introducing tube 20, the joined portion being joined to the vessel body 10. The tube protecting parts 40 are preferably constituted by sheet members 50 and 60 that form the vessel body 10.Type: GrantFiled: June 27, 2018Date of Patent: October 25, 2022Assignees: THE UNIVERSITY OF TOKYO, JMS CO., LTD.Inventors: Tokiko Nagamura, Motoki Nakano
-
Publication number: 20220333090Abstract: The present invention aims to provide a modified Cas9 protein with relaxed restriction on target sequence while maintaining binding ability to guide RNA, and use thereof. A protein containing the amino acid sequence of SEQ ID NO: 1 in which the 1335-position arginine is mutated into alanine (R1335A), isoleucine (R1335I), methionine (R1335M), threonine (R1335T) or valine (R1335V), the 1111-position leucine is mutated into arginine (L1111R), the 1135-position aspartic acid is mutated into valine (D1135V), the 1218-position glycine is mutated into arginine (G1218R), the 1219-position glutamic acid is mutated into phenylalanine (E1219F), the 1322-position alanine is mutated into arginine (A1322R), and the 1337-position threonine is mutated into arginine (T1337R), and the like.Type: ApplicationFiled: June 24, 2022Publication date: October 20, 2022Applicant: The University of TokyoInventors: Osamu NUREKI, Hiroshi NISHIMASU, Hisato HIRANO
-
Publication number: 20220336119Abstract: A novel dopant according to the present disclosure includes an anion represented by the following Formula (1) and a counter cation. In Formula (1), R1 and R2 may be each at least one group selected from a nitro group, a cyano group, an acyl group, a carboxyl group, an alkoxycarbonyl group, a haloalkyl group, a sulfo group, an alkylsulfonyl group, an halosulfonyl group, and a haloalkylsulfonyl group, or may be a group formed by R1 and R2 bonded to each other [—SO2-L-SO2—] (where L represents a haloalkylene group). The counter cation may be a radical cation represented by Formula (2), where R1 and R2 represent electron-withdrawing groups that may be bonded to each other to form a heterocycle, and R3 to R5 represent a hydrogen atom, a hydrocarbon group that may have a substituent, or a heterocyclic group that may have a substituent. The dopant is capable of forming an electroconductive composition that shows a high conductivity.Type: ApplicationFiled: August 17, 2020Publication date: October 20, 2022Applicants: The University of Tokyo, Daicel CorporationInventors: Toshihiro OKAMOTO, Tadanori KUROSAWA, Junichi TAKEYA, Daiji IKEDA, Yasuyuki AKAI
-
Patent number: 11473552Abstract: A wave power generation system includes: a hydraulic pump device configured to operate by force of a wave to discharge an operating liquid to a main passage; a hydraulic motor device configured to be rotated by the operating liquid flowing through the main passage; a power generator configured to be driven by the hydraulic motor to generate electric power; and a heat exchanger device configured to perform heat exchange of the operating liquid. The heat exchanger device includes a heat exchange motor device connected to the main passage through a sub passage and configured to be operated by the operating liquid introduced through the sub passage, a refrigerant pump device driven by the heat exchange motor device and configured to suck and discharge a refrigerant liquid, and a heat exchanger to which the refrigerant liquid discharged from the heat exchange pump device and the operating liquid are introduced.Type: GrantFiled: February 6, 2019Date of Patent: October 18, 2022Assignees: THE UNIVERSITY OF TOKYO, KAWASAKI JUKOGYO KABUSHIKI KAISHAInventors: Koki Maruyama, Chang-Kyu Rheem, Hidetaka Kobayashi, Naoki Kuribayashi, Hideki Tanaka, Masahide Tsuji
-
Patent number: 11471343Abstract: A travelling apparatus having a high travelling performance with a simple structure is provided. A travelling apparatus according to an embodiment includes: a frame; front wheels disposed in a front of the frame; first links configured to be extendable and retractable and coupled between the front wheels and an oscillation axis located in a rear of the front wheels; and first linear motion mechanisms that are coupled between the frame and the first links and are extended and retracted so as to rotate the first links about the oscillation axis.Type: GrantFiled: April 2, 2020Date of Patent: October 18, 2022Assignees: TOYOTA JIDOSHA KABUSHIKI KAISHA, THE UNIVERSITY OF TOKYOInventors: Tomoyuki Takahata, Yusuke Kosaka, Takashi Izuo
-
Patent number: 11472845Abstract: A synthetic peptide provided by the present invention includes: (1) a CTLA4-SP-related sequence; and (2) an amino acid sequence that functions as a cell penetrating peptide, wherein the synthetic peptide has a total number of amino acid residues of 100 or less.Type: GrantFiled: October 8, 2020Date of Patent: October 18, 2022Assignees: TOAGOSEI CO., LTD, The University of TokyoInventors: Nahoko Baileykobayashi, Tetsuhiko Yoshida, Shuichi Asakawa
-
Patent number: 11472130Abstract: A method of manufacturing a composite member including an aluminum member and a resin member bonded to each other, the method including: performing blasting on a surface of the aluminum member; modifying the surface of the aluminum member into aluminum hydroxide, the modifying including causing the surface of the aluminum member having undergone blasting to react with water by using at least one of heat and plasma; and directly bonding the resin member to the surface of the aluminum member modified to the aluminum hydroxide.Type: GrantFiled: February 12, 2020Date of Patent: October 18, 2022Assignees: The University of Tokyo, The Foundation for the Promotion of Industrial ScienceInventors: Nayuta Horie, Eiji Yamaguchi, Yusuke Kajihara, Fuminobu Kimura, Gota Suzuki
-
Publication number: 20220326223Abstract: The present invention provides a method for screening a substance that controls APP669 N-terminal cleavage activity, the method comprising: causing a candidate substance to act on a cultured cell; measuring an AP-related peptide produced from the cultured cell; and evaluating APP669 N-terminal cleavage activity. The candidate substance is selected, for example, from the group consisting of a low molecular weight compound, a peptide, a protein, and a nucleic acid. The present invention also provides an APP669 N-terminal cleavage enzyme containing ADAMTS4.Type: ApplicationFiled: March 30, 2020Publication date: October 13, 2022Applicants: SHIMADZU CORPORATION, THE UNIVERSITY OF TOKYOInventors: Naoki KANEKO, Taisuke TOMITA, Yota YOSHIZAWA, Masaya MATSUZAKI, Miyabishara YOKOYAMA
-
Patent number: 11468248Abstract: Input unit to which a voltage is applied, current output unit that outputs a high level current or a low level current in response to the voltage applied to input unit, and stochastic circuit unit that, in response to the voltage applied to input unit, changes a probability that the high level current or the low level current is output from current output unit, in accordance with a sigmoid function used in a mathematical model of a neural activity are included.Type: GrantFiled: April 3, 2018Date of Patent: October 11, 2022Assignees: NEC CORPORATION, THE UNIVERSITY OF TOKYOInventors: Yusuke Sakemi, Takashi Kohno
-
Patent number: 11464597Abstract: [Problem] An adhesion-preventing material having a high adhesion-preventing effect has been demanded. [Solution] An adhesion-preventing material including a sterilized biocompatible sponge-like laminate, wherein the sponge-like laminate comprises a sponge-like first layer and a sponge-like second layer each of which is at least partially crosslinked with a curing agent and comprises a low-endotoxin alginic acid monovalent metal salt, the alginic acid monovalent metal salt in the first layer has a weight average molecular weight of 10,000 to 2,000,000, the alginic acid monovalent metal salt in the second layer has a weight average molecular weight of 1,000 to 1,000,000, the weight average molecular weights are measured by a GPC-MALS method after a decrosslinking treatment, and the weight average molecular weight of the alginic acid monovalent metal salt in the first layer is higher than that in the second layer.Type: GrantFiled: July 13, 2017Date of Patent: October 11, 2022Assignees: The University of Tokyo, Mochida Pharmaceutical Co., Ltd.Inventors: Taichi Ito, Seiichi Ohta, Norihiro Kokudo, Mitsuko Isaji, Satoshi Shimizu
-
Publication number: 20220318299Abstract: To provide database generation techniques that can accurately and efficiently generate a database useable in text-based sound signal search. A sound signal database generation apparatus includes: a latent variable generation unit that generates, from a sound signal, a latent variable corresponding to the sound signal using a sound signal encoder; a data generation unit that generates a natural language representation corresponding to the sound signal from the latent variable and a condition concerning an index for a natural language representation using a natural language representation decoder; and a sound signal database generation unit that generates a record including the natural language representation corresponding to the sound signal and the sound signal from the natural language representation corresponding to the sound signal and the sound signal, and generates a sound signal database made up of the record.Type: ApplicationFiled: April 8, 2020Publication date: October 6, 2022Applicants: NIPPON TELEGRAPH AND TELEPHONE CORPORATION, The University of TokyoInventors: Kunio KASHINO, Shota IKAWA
-
Publication number: 20220315731Abstract: A carbon fiber reinforced composite material includes carbon fiber and a thermosetting resin composition. The thermosetting resin composition is a cured product of a liquid composition that contains unsaturated polyester, a curing agent, a polymerization initiator, and a nanocarbon/nanocellulose complex containing nanocarbon modified by functional a group and nanocellulose. The nanocarbon/nanocellulose complex is dispersed in the thermosetting resin composition. The thermosetting resin composition contains 0.05 to 15% by weight of the nanocarbon/nanocellulose complex. A maximum point stress of the carbon fiber reinforced composite material in a tensile test according to JIS K 7164 is 410 N/mm2 or more. A maximum point stress of the carbon fiber reinforced composite material in a three-point bending test according to JIS K 7171 is 310 N/mm2 or more.Type: ApplicationFiled: June 23, 2020Publication date: October 6, 2022Applicants: The University of TokyoInventors: Ichiro SAKATA, Bunshi FUGETSU, Takayuki UEKI, Akio MORIMOTO, Naoyuki FURUSHO