Abstract: A neuron device may include an input unit, a synapse unit, and an output unit. The synapse unit can be connected with the input unit and may include one or more synapse modules. Each of the one or more synapse modules may include multiple synapse elements connected in series and may be configured to operate in a time division multiplexing mode. Each synapse element may have specific coefficient information. In each of the one or more synapse modules, one of the multiple synapse elements connected in series may be configured to apply coefficient information to one of the multiple input signals received by the input unit. The output unit may obtain a weighted sum of the multiple input signals and may generate an output signal based on the weighted sum.
Type:
Grant
Filed:
October 1, 2015
Date of Patent:
November 10, 2020
Assignee:
SEOUL NATIONAL UNIVERSITY R&DB FOUNDATION
Inventors:
Jaeha Kim, Yunju Choi, Joonseok Yang, Seungheon Baek
Abstract: The present invention discloses a method for treating or/and preventing calcium deficiency-related diseases, which comprises administering a composition containing an effective amount of a peptide to a subject, wherein the peptide has an amino acid sequence as shown in SEQ ID NO. 3. The calcium ions are allowed to bind to the peptide and enter the cells of the patient, to achieve the effect of treating or/and preventing calcium deficiency-related diseases.
Abstract: An external information platform in conjunction with an intelligent wearable outfit provides various functional modules for measuring physiological signals in a modular design. An appropriate functional module (or even more than one functional module if desired) may be selected therefrom and arranged in the wearable outfit to extend and change functions of the wearable outfit, making the intelligent wearable outfit suitable for most users who can manage personal health appropriately.
Type:
Grant
Filed:
December 1, 2019
Date of Patent:
November 10, 2020
Assignee:
NATIONAL CHENG KUNG UNIVERSITY
Inventors:
Shuenn-Yuh Lee, Pau-Choo Chung, Jia-Hua Hong
Abstract: A genetically engineered arginine deiminase reconstructed by site-directed mutagenesis belongs to the technical field of genetic engineering technology. Its amino acid sequence is shown as SEQ ID No. 1. In the amino acid sequence of the arginine deiminase reconstructed by site-directed mutagenesis, glycine at position 264 is mutated to proline, compared to an amino acid sequence of native arginine deiminase. Compared with wild type enzyme, the effective pH range effect of the mutated arginine deiminase according to the present invention is broadened to a certain extent, and especially a good enzyme activity is achieved at physiological pH 7.4. With the broadening of the effective pH effect range, the mutant enzyme still has higher stability under the condition of pH 5.5-7.5.
Type:
Grant
Filed:
January 11, 2019
Date of Patent:
November 10, 2020
Assignee:
Jiangnan University
Inventors:
Tao Zhang, Bo Jiang, Hangyu Jiang, Wanmeng Mu, Ming Miao
Abstract: An exemplary embodiment of the present invention provides an optical element including a first polarizer and a second polarizer disposed to be perpendicular to each other, and a cell disposed between the first polarizer and the second polarizer. The cell includes a first substrate and a second substrate facing each other, an electrode positioned between the first substrate and the second substrate, and a dispersion disposed between the first substrate and the second substrate and including at least one of peeled ?-ZrP particles and peeled ?-TiP particles. The peeled ?-ZrP particles and the peeled ?-TiP particles are in a nematic state. The orientation of at least one of the ?-ZrP particles or the ?-TiP particles is changed by an electric field applied to the electrode.
Type:
Grant
Filed:
June 26, 2018
Date of Patent:
November 10, 2020
Assignee:
RESEARCH & BUSINESS FOUNDATION SUNGKYUNKWAN UNIVERSITY
Abstract: Disclosed is a decoding method which uses an intra-screen prediction. A decoding method which uses an intra prediction performed in a decoding apparatus comprises the steps of: receiving a bit stream; obtaining decoding information from the received bit stream; generating a prediction block for a current block to be decoded using the obtained decoding information; and restoring the current block by adding a residual block obtained from the bit stream and the prediction block. Accordingly, a compression ratio of an image can be improved.
Type:
Grant
Filed:
May 2, 2017
Date of Patent:
November 10, 2020
Assignee:
Industry-University Cooperation Foundation Hanyang University
Abstract: The invention provides compositions, methods, and vaccines that may stimulate the immune system and that may be used for treating malignancies associated with overexpression of the HER3 protein. Such compositions include epitopes of the HER3 protein.
Type:
Grant
Filed:
April 7, 2016
Date of Patent:
November 10, 2020
Assignee:
THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA
Abstract: Provided herein are naphthoquinones compounds such as those with a hydrogen bond donating group of the formula (I): wherein: R1, R2, R3, R4, R5, and n are as defined herein. Also provided herein are pharmaceutical composition of the present compounds and methods of treatment using the compounds including their use in the treatment of cancer.
Type:
Grant
Filed:
December 16, 2016
Date of Patent:
November 10, 2020
Assignee:
The Board of Regents of the University of Texas System
Abstract: The present invention provides for a composition of matter comprising: poly(9,9-dioctylfluorene-co-fluorenone-co-methylbenzoic ester)(PFM), carbon nanotubes (CNT), and sulfur particles nanocomposite, wherein the nanocomposite is porous. The present invention also provides for an electrode comprising: poly(9,9-dioctylfluorene-co-fluorenone-co-methylbenzoic ester)(PFM), carbon nanotubes (CNT), and sulfur particles nanocomposite, wherein the nanocomposite is porous. The present invention also provides for a lithium sulfur (Li—S) battery comprising: an electrode comprising poly(9,9-dioctylfluorene-co-fluorenone-co-methylbenzoic ester)(PFM), carbon nanotubes (CNT), and sulfur particles nanocomposite, wherein the nanocomposite is porous.
Type:
Grant
Filed:
July 23, 2018
Date of Patent:
November 10, 2020
Assignee:
The Regents of the University of California
Abstract: A coating head includes a coating device and at least a first flexible blade that is capable of being shaped into contact with a solvent-containing film on a substrate upon pressing the first flexible blade against the film, thereby providing contact between the blade and the film over a contact distance when the coating head is drawn over the substrate. The coating device and the blade are separated by a spacing distance such that partial loss of solvent occurs from a starting film formed on the substrate by the coating device as the coating head is drawn over the substrate, the partial solvent loss forming the solvent-containing film. A method of producing a film having a hierarchical structure includes drawing a coating head across a substrate to form on the substrate via the coating device a starting film including a solvent and a material for forming the hierarchical structure.
Abstract: The present technology is directed to compounds, compositions, and methods related to non-morphinan-like kappa opioid receptor (KOR) antagonists. The technology is suited to treat addiction, diuresis, depression, post traumatic stress disorder, an eating disorder, panic disorder, social anxiety disorder, general anxiety disorder, obsessive compulsive disorders, excessive or unreasonable specific phobias, and/or other conditions related to anxiety or aversion-reward responses.
Type:
Grant
Filed:
November 2, 2018
Date of Patent:
November 10, 2020
Assignees:
University of Kansas, THE SCRIPPS RESEARCH INSTITUTE
Inventors:
Jeffrey Aube, Kevin Frankowski, Thomas Prisinzano, Laura Bohn
Abstract: Methods, devices, and compositions for use with spintronic devices such as magnetic random access memory (MRAM) and spin-logic devices are provided. Methods include manipulating magnetization states in spintronic devices and making a structure using spin transfer torque to induce magnetization reversal. A device described herein manipulates magnetization states in spintronic devices and includes a non-magnetic metal to generate spin current based on the giant spin Hall effect, a ferromagnetic thin film with perpendicular magnetic anisotropy, an oxide thin film, and an integrated magnetic sensor. The device does not require an insertion layer between a non-magnetic metal with giant spin Hall effect and a ferromagnetic thin film to achieve perpendicular magnetic anisotropy.
Abstract: A noncovalent soft elastomer includes a binary block copolymer composed of an A block and a B block and a solvent, wherein the B block has a noncovalent-bonding functional group, and the solvent is a nonvolatile liquid which has a property of dissolving the B block but not dissolving the A block and which forms a functional group capable of noncovalent-bonding of the B block.
Type:
Grant
Filed:
April 27, 2016
Date of Patent:
November 10, 2020
Assignee:
NATIONAL UNIVERSITY CORPORATION TOKAI NATIONAL HIGHER EDUCATION AND RESEARCH SYSTEM
Abstract: Composite materials are provided that include a host material, nanoscale high conductive particles, and microscale high conductive particles. The nanoscale high conductive particles and the microscale high conductive particles may increase the through thickness thermal conductivity of the composite material by at least 4.0 W/(m·K), as compared to the same composite material without the nanoscale high conductive particles and microscale high conductive particles. Methods for making the composite materials herein also are provided.
Type:
Grant
Filed:
February 1, 2018
Date of Patent:
November 10, 2020
Assignee:
Florida State University Research Foundation, Inc.
Abstract: A client device includes a processor and an antenna. The client device obtains an announcement that specifies a winning client of a channel contention competition; identifies a group association of the client device using an identity of the winning client; transmits a preamble modulated by an entry of a preamble interference nullification matrix, the entry is based on the group association; and transmits, after transmitting the preamble, a data transmission. The preamble is transmitted at the same time as a second preamble is transmitted by a second client device.
Type:
Grant
Filed:
December 15, 2016
Date of Patent:
November 10, 2020
Assignee:
William Marsh Rice University
Inventors:
Adriana B. Flores Miranda, Edward W. Knightly
Abstract: A submicron structure comprising a silica body defining a plurality of pores that are suitable to receive molecules therein, and having a surface, and a phospholipid bilayer coating the surface, wherein said submicron structure has a maximum dimension of less than one micron, and wherein the phospholipid bilayer stably seals the plurality of pores; and wherein the submicron structure is a member of a monodisperse population of submicron structures.
Type:
Grant
Filed:
March 5, 2014
Date of Patent:
November 10, 2020
Assignee:
The Regents of the University of California
Inventors:
Andre E. Nel, Jeffrey I. Zink, Huan Meng
Abstract: A sensor for detecting and distinguishing between increasing and decreasing proximity of a pointing element, touch by a pointing element, pressure applied by a pointing element, stretching (and/or other deformation) of the sensor, and any of the above while stretching and/or otherwise deforming the sensor. The sensor may comprise a cluster sensor unit having a first sensor and a second sensor wherein the first sensor has a higher ratio of distal flux to proximate flux as compared to the second sensor. With this flux characteristic, the first sensor is relatively more sensitive (as compared to the second sensor) to proximity of a pointing element, while the second sensor is relatively more sensitive (as compared to the first sensor) to force and/or pressure applied by the pointing element.
Abstract: This invention relates to compositions and methods for the differential detection of multiple viruses using a one-step assay. The viruses to be detected include Zika, West Nile, dengue (genotype 1-4) and chikungunya viruses. In particular, the invention relates to a method of and assay for differential detection of the viruses using specific primers and probes designed to detect and differentiate between the viruses.
Type:
Grant
Filed:
March 17, 2017
Date of Patent:
November 10, 2020
Assignee:
THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK
Inventors:
Walter Ian Lipkin, Nischay Mishra, Thomas Briese, Rafal Tokarz