Patents Assigned to The University
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Patent number: 12291952Abstract: Methods of cleanup for hydraulic fracturing operations using a polymeric thickening agent may include use of exothermically reactive salts. For example, a method of cleanup may include use of a first fluid including a first exothermically reactive salt and a second fluid including a second exothermically reactive salt. Upon introduction into a subterranean reservoir, exothermically reactive salts may undergo an exothermic reaction to generate heat, and such heat generated from the exothermic reaction may break a polymeric thickening agent and decrease viscosity thereof.Type: GrantFiled: September 21, 2023Date of Patent: May 6, 2025Assignees: SAUDI ARABIA, KING FAHD UNIVERSITY OF PETROLEUM & MINERALSN OIL COMPANYInventors: Ali Abdullah Al-Taq, Sajjad A. Aldarweesh, Murtada S. Al-Jawad
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Patent number: 12292327Abstract: A near-field probe (and associated method) compatible with near-infrared electromagnetic radiation and high temperature applications above 300° C. (or 500° C. in some applications) includes an optical waveguide and a photonic thermal emitting structure comprising a near-field thermally emissive material coupled to or part of the optical waveguide. The photonic thermal emitting structure is structured and configured to emit near-field energy responsive to at least one environmental parameter of interest, and the near-field probe is structured and configured to enable extraction of the near-field energy to a far-field by coupling the near-field energy into one or more guided modes of the optical waveguide.Type: GrantFiled: May 17, 2024Date of Patent: May 6, 2025Assignees: University of Pittsburgh—Of the Commonwealth System of Higher Education, Carnegie Mellon UniversityInventors: Paul Richard Ohodnicki, Sheng Shen
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Patent number: 12292666Abstract: A form of a color-changeable plastic includes: a first conductive electrode layer; a color change layer disposed on the first conductive electrode layer, configured to cover a top surface of the first conductive electrode layer, and made of a substance that changes color depending on whether a voltage is applied; a second conductive electrode layer disposed on the color change laver, configured to cover a top surface and side surfaces of the color change layer, and configured to change the color of the color change layer with the first conductive electrode layer when the voltage is applied; and a conductive guide disposed at at least one of the first conductive electrode layer or the second conductive electrode layer, and configured to guide a movement of electrons and a color change direction of the color change layer when the voltage is applied.Type: GrantFiled: June 8, 2021Date of Patent: May 6, 2025Assignees: Hyundai Motor Company, Kia Corporation, Pusan National University Industry-University Cooperation FoundationInventors: Dong Eun Cha, Hyun Kyung Kim, Jong Seung Park, Jun Hong Choi
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Patent number: 12290386Abstract: A multi-lead electrocardiogram (ECG) signal classification method based on self-supervised learning relates to the technical field of ECG signal classification. The method includes: processing an original signal through different data augmentation methods, designing an appropriate encoder module, extracting a feature of an ECG signal through a large amount of easily available unlabeled data such that an encoder learns more class information of the ECG signal, fine-tuning the model encoder with a small amount of labeled data for feature optimization, and continuously optimizing a parameter of a feature extractor by training a model such that a generated feature well reflects a structure and information of input data. Through self-supervised learning, the method reduces obstacles caused by performing ECG signal classification through a large amount of expensive manually labeled data, improving the generalization ability of the model.Type: GrantFiled: May 15, 2024Date of Patent: May 6, 2025Assignees: QILU UNIVERSITY OF TECHNOLOGY (SHANDONG ACADEMY OF SCIENCES), SHANDONG COMPUTER SCIENCE CENTER (NATIONAL SUPERCOMPUTING CENTER IN JINAN)Inventors: Yinglong Wang, Wei Liu, Minglei Shu, Pengyao Xu, Shuwang Zhou, Zhaoyang Liu
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Patent number: 12292138Abstract: A pipe connector for use in high temperature environments, such as those characteristics of molten salt reactors. The pipe connector can be used in any industry that uses pipe connectors, and in particular, can be used in a molten salt system including a reactor requiring a connection rated for a maximum of about 725° C. and about 15,000 psi. The pipe connector may comprise a pin, a seal ring, a retainer ring, a box, a locking nut, and a retaining nut.Type: GrantFiled: March 11, 2022Date of Patent: May 6, 2025Assignee: Abilene Christian UniversityInventors: Rusty Towell, Thomas Bailey, Tim Head
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Patent number: 12290428Abstract: An osmotic sanitary collection bag for collecting fluid discharged from the vagina during menstruation. The osmotic sanitary collection bag includes an absorbent sponge having a plurality of drainage apertures disposed therethrough. Elongated adhesive strips extend away from the sponge and are adhered to a first surface of a conventional sanitary device to secure the osmotic sanitary collection bag in place. A collection bag abuts the absorbent sponge and is disposed in underlying relation to the absorbent sponge and the drainage apertures. The absorbent sponge is laced with salt, alcohol, and an odor-masking substance, such as sodium bicarbonate.Type: GrantFiled: September 21, 2023Date of Patent: May 6, 2025Assignee: Florida A&M UniversityInventor: Charles Magee
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Patent number: 12293291Abstract: A system for time series analysis using attention models is disclosed. The system may capture dependencies across different variables through input embedding and may map the order of a sample appearance to a randomized lookup table via positional encoding. The system may capture capturing dependencies within a single sequence through a self-attention mechanism and determine a range of dependency to consider for each position being analyzed. The system may obtain an attention weighting to other positions in the sequence through computation of an inner product and utilize the attention weighting to acquire a vector representation for a position and mask the sequence to enable causality. The system may employ a dense interpolation technique for encoding partial temporal ordering to obtain a single vector representation and a linear layer to obtain logits from the single vector representation. The system may use a type dependent final prediction layer.Type: GrantFiled: July 5, 2023Date of Patent: May 6, 2025Assignees: Arizona Board of Regents on Behalf of Arizona State University, Lawrence Livermore National Security, LLCInventors: Andreas Spanias, Huan Song, Jayaraman J. Thiagarajan, Deepta Rajan
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Patent number: 12290541Abstract: Disclosed are a strain of Lactobacillus helveticus capable of removing multiple heavy metals and an application thereof in milk powder, where the strain is Lactobacillus helveticus KD-3, which is deposited in the China Center for Type Culture Collection on Apr. 6, 2023, with a deposit number of CCTCC NO: M2023479. The Lactobacillus helveticus KD-3 has a cadmium resistant gene czcD, a chromium resistant gene chrA and a lead resistant gene pbrT, and is capable of tolerating single and compound heavy metals (cadmium, chromium and lead). The Lactobacillus helveticus KD-3 of the present disclosure is used to prepare lyophilized bacterial powder.Type: GrantFiled: August 20, 2024Date of Patent: May 6, 2025Assignee: SHAANXI UNIVERSITY OF SCIENCE AND TECHNOLOGYInventors: Guowei Shu, Ke Zhang, Huan Lei, Qisheng Hu, Guanli Du, Qiqi Zheng, Guoliang Li, Qinfeng Xu, Chunji Dai, Ting Li, Wenjing Hu, Lihao Xu, Chaowei Yang, Jie Qiao
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Patent number: 12291699Abstract: The presently disclosed subject matter provides a biomimetic lung disease model, and methods of its production and use. In one exemplary embodiment, the biomimetic lung disease model can include a first and second microchannel with a membrane coated with airway epithelial cells disposed between the microchannels and at least one device coupled to the biomimetic model that delivers an agent to at least one microchannel. In certain embodiments, the agent is cigarette smoke.Type: GrantFiled: October 11, 2023Date of Patent: May 6, 2025Assignee: The Trustees of the University of PennsylvaniaInventors: Dongeun Huh, Mark Mondrinos, Woo Yul Byun
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Patent number: 12291724Abstract: Disclosed are compositions and methods for ex vivo expansion of tumor infiltrating lymphocytes for use in adoptive cell therapy (ACT). Also disclosed are compositions and method for identifying an agent for ex vivo expansion of tumor infiltrating lymphocytes for use in ACT. Also disclosed are methods for treating cancer using tumor-infiltrating lymphocytes expanded by the disclosed methods.Type: GrantFiled: May 24, 2022Date of Patent: May 6, 2025Assignees: H. LEE MOFFITT CANCER CENTER AND RESEARCH INSTITUTE, INC., UNIVERSITY OF SOUTH FLORIDAInventors: Amod A. Sarnaik, Shari Pilon-Thomas, Mark McLaughlin, Hao Liu
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Patent number: 12293833Abstract: The present invention relates to a technical idea of monitoring a heart condition by analyzing biosignals measured using a sensor device for detecting a heart condition. In a method of monitoring a heart condition according to one embodiment of the present invention, electrocardiogram signals are measured from a user, feature information is extracted by performing machine learning of the time domain of the measured electrocardiogram signals, a plurality of cardiac abnormality type models are determined by performing machine learning of the extracted feature information, classification accuracy for the determined cardiac abnormality type models is calculated, and a cardiovascular disease of the user is determined using the determined cardiac abnormality type models and public cardiovascular disease data based on the calculated accuracy. That is, the present invention relates to a technique for assisting medical diagnosis.Type: GrantFiled: June 11, 2021Date of Patent: May 6, 2025Assignee: Korea University Research and Business FoundationInventors: Dong Joo Kim, Young Tak Kim, Hyun Ji Kim
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Patent number: 12291763Abstract: A high-strength and tough multi-component soft magnetic alloy and preparation method thereof are provided. The high-strength and tough multi-component soft magnetic alloy is composed of the following components in atomic percentage: Fe 32-45%, Co 24-29%, Ni 24-29%, Al 2.5-8%, Ti 1.5-3.5%, Ta 1.0-5%, Nb 0-2%, and Mo 0-2%. The multi-component alloys prepared by the present invention exhibit a face-centered cubic structure of the matrix, featured with high strength, high ductility, low coercivity and relatively high saturation magnetization. These properties make it suitable for manufacturing critical components for applications in industries such as electrical engineering, automatic control, mobile communications, and others.Type: GrantFiled: July 10, 2023Date of Patent: May 6, 2025Assignee: Central South UniversityInventors: Zhiming Li, Penghua Ge, Dingshun Yan, Kefu Gan, Yong Zhang
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Patent number: 12293804Abstract: The disclosure provides a convolution operation accelerator and a convolution operation method and belongs to the field of microelectronic devices. Input data of each word line may be subjected to a multiply-accumulate operation together with two upper and lower layers of convolution kernel units, so that natural sliding of the convolution kernel units in a y direction in two-dimensional input is achieved. The oblique bit lines and multiple copies of a convolution kernel in each layer of a non-volatile memory array may enable a multiplication operation between one piece of input data and convolution kernel data at different positions in the same convolution kernel. In this way, the natural sliding of the convolution kernel units in an x direction in the two-dimensional input is achieved.Type: GrantFiled: April 20, 2022Date of Patent: May 6, 2025Assignee: HUAZHONG UNIVERSITY OF SCIENCE AND TECHNOLOGYInventors: Xiangshui Miao, Jiawei Fu, Yuhui He
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Patent number: 12295246Abstract: A heater for an evaporator includes a heating wire and a support, and the heating wire includes a tunnel part that surrounds an outer surface of a container in which an organic material is accommodated and is coiled in a cylindrical shape, a flange part that is connected to an upper end of the tunnel part and has a spiral structure in which a radius increases in a plane direction, a first straight part extending downward from a lower end of the tunnel part, and a second straight part extending downward from a distal end of the flange part, and the support includes a ring part that supports a lower surface of the flange part, and a plurality of bars extending downward form the ring part.Type: GrantFiled: April 19, 2022Date of Patent: May 6, 2025Assignee: INDUSTRY-UNIVERSITY COOPERATION FOUNDATION SUNMOON UNIVERSITYInventor: Young Wook Park
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Patent number: 12293908Abstract: A mass spectrometer may have an ion source region including an ion generator configured to generate ions from a sample, an ion detector configured to detect ions and produce corresponding ion detection signals, an electric field-free drift region disposed between the ion source region and the ion detector through which the generated ions drift axially toward the ion detector, a plurality of spaced-apart charge detection cylinders disposed in the drift region and through which the ions drifting axially through the drift region pass, and a plurality of charge amplifiers each coupled to a different one of the plurality of charge detection cylinders and each configured to produce a charge detection signal corresponding to a magnitude of charge of one or more of the generated ions passing through a respective one of the plurality of charge detection cylinders.Type: GrantFiled: December 16, 2020Date of Patent: May 6, 2025Assignee: THE TRUSTEES OF INDIANA UNIVERSITYInventors: Martin F. Jarrold, David E. Clemmer
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Patent number: 12295154Abstract: A wide bandgap semiconductor structure for an irradiation characteristic test includes a substrate with metal plates and a wide bandgap semiconductor part. The wide bandgap semiconductor part includes a gallium nitride layer, a barrier layer, P-type gallium nitride layers, source ohmic metal layers, and drain ohmic metal layers. The P-type gallium nitride layers are connected to a gate interconnection metal layer via gate metal layers and metal lead wires. A gate top metal layer is provided on the gate interconnection metal layer. Each source ohmic metal layer is provided with a source interconnection metal layer and source top metal layers. Each drain ohmic metal layer is provided with a drain interconnection metal layer and drain top metal layers. The wide bandgap semiconductor part is connected to the metal plates through the source top metal layers, the drain top metal layers, and the gate top metal layer.Type: GrantFiled: December 30, 2024Date of Patent: May 6, 2025Assignee: NANJING UNIVERSITYInventors: Feng Zhou, Yu Rong, Hai Lu, Weizong Xu, Dong Zhou, Fangfang Ren
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Patent number: 12291502Abstract: A compound, or a pharmaceutically acceptable salt, solvate or prodrug thereof, having the chemical structure of formula I as defined in the text and methods of using these compounds to inhibit topoisomerase II? and treat or prevent metastasis of cancer in a subject.Type: GrantFiled: April 1, 2020Date of Patent: May 6, 2025Assignee: The Regents of the University of Colorado, A Body CorporateInventors: Daniel V. LaBarbera, Qiong Zhou, Adedoyin D. Abraham
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Patent number: 12291607Abstract: Provided is a macromolecular material that has self-healing properties, excellent stretchability, and a high degree of freedom in the design of stretchability, strength, and hardness, and that can be produced by a simple method; and also provided is a method for producing the same. The macromolecular material of the present invention comprises a polymer having a host group and a guest group. The host group is a monovalent group formed by removing one hydrogen atom or hydroxy group from a cyclodextrin derivative. The polymer is a polymer of a monomer mixture containing a host group-containing polymerizable monomer, a guest group-containing polymerizable monomer, and a third polymerizable monomer, and the third polymerizable monomer contains a (meth)acrylic ester compound. The host group-containing polymerizable monomer and the guest group-containing polymerizable monomer have a property of being dissolved in the third polymerizable monomer.Type: GrantFiled: March 6, 2020Date of Patent: May 6, 2025Assignees: OSAKA UNIVERSITY, YUSHIRO CHEMICAL INDUSTRY CO., LTD.Inventors: Akira Harada, Hiroyasu Yamaguchi, Yoshinori Takashima, Motofumi Osaki, Yasumasa Ohashi, Hiroaki Takahashi, Hidenori Shirakawa
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Patent number: 12291725Abstract: This disclosure pertains to a non-living biological product. Particularly, exosomes derived from stem cells can help restore heart function. According to certain embodiments, a fluid-induced shear stress mechanical stimulation process of stem cells is used to augmented quantity and quality of exosomes produced from stem cells. These exosomes serve as a therapeutic agent for the regenerative repair of diseases, such as diseased heart tissues. Therefore, compositions comprising the exosomes derived from stem cells and methods of treating a degenerative disease by administering the exosomes isolated from stem cells are also provided.Type: GrantFiled: July 12, 2023Date of Patent: May 6, 2025Assignee: The Florida International University Board of TrusteesInventors: Sharan Ramaswamy, Manuel Perez, Yih-Mei Lin
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Patent number: 12291808Abstract: A heating-energy-saving equipment for printing and dyeing factory, including: a heat source generator, a first ejector, a second ejector, a setting machine and a flash drum; a steam outlet of the heat source generator is connected to an injection port of the first ejector through a pipeline, an outlet of the first ejector is connected to an injection port of the second ejector, the water outlet of the flash drum is provided with a second branch pipe which is connected to the first ejector port of the second ejector, and the steam outlet of the flash drum is connected to the second ejector port of the second ejector, the present invention can save energy and reduce production costs; can be improved upon the existing equipment without changing the main structure of existing equipment, and it is very easy to implement; can reduce the discharge heat loss and environmental pollution.Type: GrantFiled: November 6, 2024Date of Patent: May 6, 2025Assignee: GUANGDONG UNIVERSITY OF TECHNOLOGYInventors: Xiaozhou Liu, Zebin Fu