Abstract: Estrogen and progesterone replacement therapies are provided herein. Among others, the following formulations are provided herein: solubilized estradiol without progesterone; micronized progesterone without estradiol; micronized progesterone with partially solubilized progesterone; solubilized estradiol with micronized progesterone; solubilized estradiol with micronized progesterone in combination with partially solubilized progesterone; and solubilized estradiol with solubilized progesterone.
Type:
Grant
Filed:
December 6, 2013
Date of Patent:
September 30, 2014
Assignee:
TherapeuticsMD, Inc.
Inventors:
Brian A. Bernick, Janice Louise Cacace, Peter H. R. Persicaner, Neda Irani, Julia M. Amadio
Abstract: Estrogen and progesterone replacement therapies are provided herein. Among others, the following formulations are provided herein: solubilized estradiol without progesterone; micronized progesterone without estradiol; micronized progesterone with partially solubilized progesterone; solubilized estradiol with micronized progesterone; solubilized estradiol with micronized progesterone in combination with partially solubilized progesterone; and solubilized estradiol with solubilized progesterone.
Type:
Grant
Filed:
December 6, 2013
Date of Patent:
September 30, 2014
Assignee:
TherapeuticsMD, Inc.
Inventors:
Brian A. Bernick, Janice Louise Cacace, Peter H. R. Persicaner, Neda Irani, Julia M. Amadio
Abstract: According to various embodiments of this disclosure, pharmaceutical formulations comprising solubilized estradiol are provided. In various embodiments, such formulations are encapsulated in soft capsules which may be vaginally inserted for the treatment of vulvovaginal atrophy.
Type:
Application
Filed:
December 20, 2013
Publication date:
July 31, 2014
Applicant:
TherapeuticsMD, Inc.
Inventors:
Brian A. Bernick, Julia M. Amadio, Peter H.R. Persicaner, Thorsteinn Thorsteinsson, Janice Louise Cacace
Abstract: Estrogen and progesterone replacement therapies are provided herein. Among others, the following formulations are provided herein: solubilized estradiol without progesterone; micronized progesterone without estradiol; micronized progesterone with partially solubilized progesterone; solubilized estradiol with micronized progesterone; solubilized estradiol with micronized progesterone in combination with partially solubilized progesterone; and solubilized estradiol with solubilized progesterone.
Type:
Application
Filed:
December 6, 2013
Publication date:
April 10, 2014
Applicant:
TherapeuticsMD, Inc.
Inventors:
Brian A. Bernick, Janice Louise Cacace, Peter H.R. Persicaner, Neda Irani, Julia M. Amadio
Abstract: Estrogen and progesterone replacement therapies are provided herein. Among others, the following formulations are provided herein: solubilized estradiol without progesterone; micronized progesterone without estradiol; micronized progesterone with partially solubilized progesterone; solubilized estradiol with micronized progesterone; solubilized estradiol with micronized progesterone in combination with partially solubilized progesterone; and solubilized estradiol with solubilized progesterone.
Type:
Application
Filed:
December 6, 2013
Publication date:
April 10, 2014
Applicant:
TherapeuticsMD, Inc.
Inventors:
Brian A. Bernick, Janice Louise Cacace, Peter H.R. Persicaner, Neda Irani, Julia M. Amadio
Abstract: Estrogen and progesterone replacement therapies are provided herein. Among others, the following formulations are provided herein: solubilized estradiol without progesterone; micronized progesterone without estradiol; micronized progesterone with partially solubilized progesterone; solubilized estradiol with micronized progesterone; solubilized estradiol with micronized progesterone in combination with partially solubilized progesterone; and solubilized estradiol with solubilized progesterone.
Type:
Application
Filed:
December 6, 2013
Publication date:
April 10, 2014
Applicant:
TherapeuticsMD, Inc.
Inventors:
Brian A. Bernick, Janice Louise Cacace, Peter H.R. Persicaner, Neda Irani, Julia M. Amadio
Abstract: Estrogen and progesterone replacement therapies are provided herein. Among others, the following formulations are provided herein: solubilized estradiol without progesterone; micronized progesterone without estradiol; micronized progesterone with partially solubilized progesterone; solubilized estradiol with micronized progesterone; solubilized estradiol with micronized progesterone in combination with partially solubilized progesterone; and solubilized estradiol with solubilized progesterone.
Type:
Application
Filed:
December 6, 2013
Publication date:
April 10, 2014
Applicant:
TherapeuticsMD, Inc.
Inventors:
Brian A. Bernick, Janice Louise Cacace, Peter H.R. Persicaner, Neda Irani, Julia M. Amadio
Abstract: Estrogen and progesterone replacement therapies are provided herein. Among others, the following formulations are provided herein: solubilized estradiol without progesterone; micronized progesterone without estradiol; micronized progesterone with partially solubilized progesterone; solubilized estradiol with micronized progesterone; solubilized estradiol with micronized progesterone in combination with partially solubilized progesterone; and solubilized estradiol with solubilized progesterone.
Type:
Application
Filed:
December 6, 2013
Publication date:
April 3, 2014
Applicant:
TherapeuticsMD, Inc.
Inventors:
Brian A. Bernick, Janice Louise Cacace, Peter H.R. Persicaner, Neda Irani, Julia M. Amadio
Abstract: Estrogen and progesterone replacement therapies are provided herein. Among others, the following formulations are provided herein: solubilized estradiol without progesterone; micronized progesterone without estradiol; micronized progesterone with partially solubilized progesterone; solubilized estradiol with micronized progesterone; solubilized estradiol with micronized progesterone in combination with partially solubilized progesterone; and solubilized estradiol with solubilized progesterone.
Type:
Application
Filed:
December 6, 2013
Publication date:
April 3, 2014
Applicant:
TherapeuticsMD, Inc.
Inventors:
Brian A. Bernick, Janice Louise Cacace, Peter H.R. Persicaner, Neda Irani, Julia M. Amadio
Abstract: Estrogen and progesterone replacement therapies are provided herein. Among others, the following formulations are provided herein: solubilized estradiol without progesterone; micronized progesterone without estradiol; micronized progesterone with partially solubilized progesterone; solubilized estradiol with micronized progesterone; solubilized estradiol with micronized progesterone in combination with partially solubilized progesterone; and solubilized estradiol with solubilized progesterone.
Type:
Application
Filed:
December 6, 2013
Publication date:
March 27, 2014
Applicant:
TherapeuticsMd, Inc.
Inventors:
Brian A. Bernick, Janice Louise Cacace, Peter H.R. Persicaner, Neda Irani, Julia M. Amadio
Abstract: A research and development system that gathers feedback from patients and healthcare providers with respect to the their experience with various aspects of a supplier's products in order to tabulate, consolidate, compare and analyze the data received rapidly and efficiently, and which can be used on successive iterations to determine future products and services.
Type:
Application
Filed:
October 3, 2013
Publication date:
January 30, 2014
Applicant:
THERAPEUTICSMD, INC.
Inventors:
Brian A. BERNICK, Robert FINIZIO, John MILLIGAN
Abstract: Estrogen and progesterone replacement therapies are provided herein. Among others, the following formulations are provided herein: solubilized estradiol without progesterone; micronized progesterone without estradiol; micronized progesterone with partially solubilized progesterone; solubilized estradiol with micronized progesterone; solubilized estradiol with micronized progesterone in combination with partially solubilized progesterone; and solubilized estradiol with solubilized progesterone.
Type:
Grant
Filed:
November 21, 2012
Date of Patent:
January 21, 2014
Assignee:
TherapeuticsMD, Inc.
Inventors:
Brian A. Bernick, Janice Louise Cacace, Peter H. R. Persicaner, Neda Irani, Julia M. Amadio
Abstract: Hormone replacement therapies are provided comprising solubilized progesterone alone and optionally with an estrogen, cyclic/sequential and continuous-combined dosing, and administered via transdermal HRT delivery systems.
Type:
Application
Filed:
March 15, 2013
Publication date:
December 19, 2013
Applicant:
THERAPEUTICSMD, INC.
Inventors:
Brian A. Bernick, Julia M. Amadio, Peter H.R. Persicaner, Janice Louise Cacace, Neda Irani
Abstract: A research and development system that gathers feedback from patients and healthcare providers with respect to the their experience with various aspects of a supplier's products in order to tabulate, consolidate, compare and analyze the data received rapidly and efficiently, and which can be used on successive iterations to determine future products and services.
Type:
Grant
Filed:
September 17, 2009
Date of Patent:
November 5, 2013
Assignee:
TherapeuticsMD, Inc.
Inventors:
Brian Bernick, Robert Finizio, John Milligan
Abstract: Estrogen and progesterone replacement therapies are provided herein. Among others, the following formulations are provided herein: solubilized estradiol without progesterone; micronized progesterone without estradiol; micronized progesterone with partially solubilized progesterone; solubilized estradiol with micronized progesterone; solubilized estradiol with micronized progesterone in combination with partially solubilized progesterone; and solubilized estradiol with solubilized progesterone.
Abstract: In various embodiments, a research and development system that gathers feedback from patients and healthcare providers with respect to the their experience with various aspects of a supplier's products in order to tabulate, consolidate, compare and analyze the data received rapidly and efficiently, and which can be used on successive iterations to determine future products and services.
Type:
Application
Filed:
January 30, 2012
Publication date:
May 24, 2012
Applicant:
THERAPEUTICSMD, INC.
Inventors:
Robert Finizio, Brian Bernick, John Milligan