Patents Assigned to Tianjin University
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Patent number: 10604474Abstract: A method for preparing a new crystalline form of ?-aminobutyric acid, including the steps of: S1: preparing a ?-aminobutyric acid solution at an initial concentration of 0.5-1.0 g/mL by adding crude ?-aminobutyric acid to water; adding an additive to the ?-aminobutyric acid solution, raising the temperature to 50-80° C., stirring to produce a clear solution; and S2: obtaining a suspension by evaporating water from the product of S1 under reduced pressure and at 50-80° C.; obtaining a wet product by filtering the suspension; drying the wet product to obtain the new crystalline form of ?-aminobutyric acid. The preparation method of the new crystalline form of ?-aminobutyric acid is simple, easy to operate, low in energy consumption, economical and environmentally friendly. It is suitable for large-scale industrial production.Type: GrantFiled: November 7, 2016Date of Patent: March 31, 2020Assignees: Nantong Licheng Biological Engineering Co., Ltd, Tianjin UniversityInventors: Junbo Gong, Kaifei Zhao, Haiyan Xi, Xiaohua Wu, Baohong Hou, Qiuxiang Yin, Jingkang Wang, Feng Jin, Shichao Du, Qinqing Gu, Shiping Tang
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Patent number: 10508938Abstract: Fiber optical Fabry-Perot flow test device with local bending diversion structure, having an inlet flange, a test tube and an outlet flange, with both a fiber optical Fabry-Perot pressure sensor at high-pressure-side and a fiber optical Fabry-Perot pressure sensor at low-pressure-side, which are fixedly connected to the test tube through an auxiliary connecting device.Type: GrantFiled: October 27, 2016Date of Patent: December 17, 2019Assignee: Tianjin UniversityInventors: Tiegen Liu, Junfeng Jiang, Huijia Yang, Kun Liu, Shuang Wang, Weihang Zhang
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Publication number: 20190358219Abstract: Disclosed is a targeted delivery system for a hydrophobic antitumor drug, referring to conjugates of E-selectin polypeptide ligand-polyethylene glycol-antitumor drug connected by different link bridges containing disulfide bonds. The synthesis of the conjugates, antitumor activity evaluation, the particle size and morphology characteristics of nanoparticles self-assembled by the conjugates in an aqueous solution, and the release of the antitumor drug in different conditions are comprised. The conjugates can actively target at vessels of a tumor site by the E-selectin peptide ligand, and can also self-assemble into nanoparticles in an aqueous solution, so as to be passively targeted at the tumor site by EPR effect.Type: ApplicationFiled: July 21, 2016Publication date: November 28, 2019Applicant: Tianjin University of Science & TechnologyInventors: Peng YU, Na GUO, Dong WANG, Yuou TENG, Tiantian HAO, Huan LIU, Tianle ZHANG, Xiuzhuan SHANG
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Publication number: 20190359568Abstract: A novel type of water-soluble isatin derivatives, and manufacturing method and application thereof. An isatin derivative comprising a phenolic hydroxy group is used as the substrates. A dimethylaminomethylene group is introduced to an ortho position of the phenolic hydroxy group to significantly improve the water solubility of a class of compounds provided by the invention. An antitumor activity study showed that the activity of the class of compounds was not reduced, and even improved. The class of compounds has great prospects for applications in developing an antitumor pharmaceutical product.Type: ApplicationFiled: July 28, 2016Publication date: November 28, 2019Applicant: Tianjin University of Science & TechnologyInventors: Peng YU, Dong WANG, Yuou TENG, Longfei MIAO, Jing WANG, Qian ZHANG, Yuan YUAN
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Patent number: 10487044Abstract: The present invention discloses a ?-aminobutyric acid hemihydrate crystal, its molecular formula is C4H9NO2.0.5H2O. It also discloses a method of preparing a ?-aminobutyric acid hemihydrate crystal, including first adding crude ?-aminobutyric acid to water to prepare a ?-aminobutyric acid suspension at an initial concentration of 1.2-2.0 g/mL; then stirring the suspension at a constant temperature of 5-10° C. for 6-12 hours, followed by filtering and drying to obtain the ?-aminobutyric acid hemihydrate crystal. The ?-aminobutyric acid hemihydrate crystal is stable, does not easily absorb moisture and agglomerate, and is convenient for further processing and use. The crystal has a large main particle size, uniform particle size distribution, high bulk density, good flowability, and a purity of ?99%. The preparation method of the crystal according to the present invention is simple, easy to operate, highly efficient and low in energy consumption, and is suitable for large-scale industrial production.Type: GrantFiled: November 11, 2016Date of Patent: November 26, 2019Assignees: Nantong Licheng Biological Engineering Co., Ltd, Tianjin UniversityInventors: Junbo Gong, Qinqing Gu, Kaifei Zhao, Jiangbo Li, Baohong Hou, Qiuxiang Yin, Jingkang Wang, Yi Sun, Shichao Du, Xin Pan, Zhongshi Liu
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Publication number: 20190345902Abstract: The present invention discloses a novel low-temperature fuel reforming unit based on combined external reformer of an engine, comprising an engine cylinder and an external low-temperature fuel reformer; the external low-temperature fuel reformer is winded with a heater strip and is provided with a first temperature controlled meter, the inlet of the external low-temperature fuel reformer is connected with a air inlet pipe and a fuel sample injection pipe, and a flow meter is arranged on the air inlet pipe; the fuel sample injection pipe is connected with a fuel injection pump and a fuel vaporization tank which is provided with a second temperature controlled meter; the outlet of the external low-temperature fuel reformer is connected with the engine inlet pipe via a reforming gas pipe; and the reformed low-temperature products enter into the engine inlet pipe via the reforming gas pipe for combining with the fresh air again to form a uniform hybrid gas, and the hybrid gas is introduced into the engine cylindeType: ApplicationFiled: March 27, 2017Publication date: November 14, 2019Applicant: Tianjin UniversityInventors: Mingfa YAO, Yang WANG, Lixia WEI, Haifeng LIU, Hu WANG, Zunqing ZHENG
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Publication number: 20190344250Abstract: The present invention provides a preparation method for a nitrogen-doped carbon-loaded metal monatomic catalyst, including: mixing a soluble metallic salt, a hydroxylamine hydrochloride, a soluble carbon source, water, and ethanol, to obtain a mixed solution, then performing drying and precipitation, to obtain a catalyst precursor, and finally performing calcination, to obtain a nitrogen-doped carbon-loaded metal monatomic catalyst. In the present invention, the metallic salt, the hydroxylamine hydrochloride, and the carbon source are fully mixed in the solution, and after being dried, are calcined, to carbonize the carbon source, so that ammonium ions are decomposed into nitrogen-doped carbon, and meanwhile, metal atoms are loaded onto the nitrogen-doped carbon. The method is simple, and costs are low.Type: ApplicationFiled: August 1, 2018Publication date: November 14, 2019Applicant: Tianjin University of TechnologyInventors: Lili HAN, Xijun LIU, Jun LUO
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Patent number: 10472654Abstract: Disclosed are very high optically pure D- and L-lactic acid fermentation production strains and construction methods thereof and the method for preparing very high optically pure D- and L-lactic acids using the strains, wherein the deposit number of the D-lactic acid fermentation production strain is CGMCC No. 11059, and the deposit number of the L-lactic acid fermentation production strain is CGMCC No. 11060.Type: GrantFiled: November 20, 2017Date of Patent: November 12, 2019Assignee: Tianjin University of Science and TechnologyInventors: Zhengxiang Wang, Kangming Tian, Dandan Niu, Fuping Lu
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Patent number: 10365126Abstract: A distributed optical fiber disturbance positioning system based on the asymmetric dual Mach-Zehnder interference, unlike traditional dual Mach-Zehnder distributed optical fiber disturbance sensing system, the present invention adopts two narrow-bandwidth optical sources (1a, 1b) and adopts corresponding DWDM (3a, 3b) before the detector (4a, 4b) to filter the backscatter noise of the optical fiber, and can solve the problems of having too low SNR due to backscatter influence when the sensing distance is long. The present invention also provides a positioning method for applying the system, which obtains the TFD of the disturbance frame signals by using the time-frequency analysis method based on the short-term average frequency, and takes the points near the point of maximum frequency as the effective signal segment for performing cross-correlation time delay estimation, thus obtaining the delay, and the disturbance position.Type: GrantFiled: October 27, 2016Date of Patent: July 30, 2019Assignee: Tianjin UniversityInventors: Kun Liu, Tiegen Liu, Junfeng Jiang, Chunyu Ma, Tianjiao Chai, Chang He, Miao Tian, Zhichen Li
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Patent number: 10365088Abstract: The present invention discloses a distributed device for simultaneously measuring strain and temperature based on optical frequency domain reflection, comprising a tunable laser, a 1:99 beam splitter, a main interferometer system, a light source phase monitoring system based on an auxiliary interferometer, an acquisition device and a computer processing unit, wherein the main interferometer system comprises two Mach-Zehnder interferometers, and two optical fibers having different cladding diameters are arranged in parallel as sensing fibers. Due to the difference in temperature and strain coefficients of optical fibers of the same diameter, the temperature and strain values during changing the temperature and strain simultaneously can be obtained by matrix operation, thereby achieving an effect of eliminating cross sensitivity of temperature and strain sensing in optical frequency domain reflection.Type: GrantFiled: October 27, 2016Date of Patent: July 30, 2019Assignee: Tianjin UniversityInventors: Zhenyang Ding, Di Yang, Tiegen Liu, Yang Du, Zhexi Xu, Kun Liu, Junfeng Jiang
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Patent number: 10367190Abstract: A cylindrical single-piece lithium-ion battery of 400 Ah includes: a cylindrical battery enclosure (1), a battery mandrel (3), a plurality of tabs (4), a wiring terminal (6), a positive and negative electrode cover (11); a positive electrode sheet, said battery positive electrode is composed of LiFePO4, conductive carbon-black, graphite, adhesive such as PVDF, and solvent such as NMP; a negative electrode sheet, the battery negative electrode is composed of lithium titanate, conductive carbon-black, graphite, adhesive such as PVDF, and solvent such as NMP. The cylindrical lithium-ion battery made by the invention has a capacity of 400 Ah which is the one reportedly having the largest capacity in the world presently.Type: GrantFiled: September 28, 2016Date of Patent: July 30, 2019Assignee: Tianjin UniversityInventors: Zhiyuan Tang, Lei Sun, Qi Wang, Guowei Ling
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Patent number: 10360519Abstract: A planning method of EV fast charging stations on the expressway, comprising the following steps: Step 1: forecasting the spatial and temporal distribution of EV charging load, that is to determine the time and location of each EV needing charging on the expressway; Step 2: based on the forecast result achieved by Step 1, determining the locations of the fast charging stations on the expressway by the nearest neighbor clustering algorithm; Step 3: according to the spatial and temporal forecast result of the EV charging load and the locations of the fast charging stations, determining the number c of the chargers in each fast charging station by queuing theory. Due to battery characteristics, traditional gas stations do not completely match the fast charging stations.Type: GrantFiled: August 28, 2015Date of Patent: July 23, 2019Assignee: Tianjin UniversityInventors: Yunfei Mu, Xiaohong Dong, Hongjie Jia, Xiaodan Yu
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Publication number: 20190178443Abstract: Method of constructing a vault of a large storage tank for liquefied natural gas by first modeling the vault with a 3-D modeling software application, then partially building the vault with a framework and a first set of covering panels fixed on the framework where the panels do not touch each other, but leave a number of gaps between them, measuring the dimensions of the actual gaps between the panels using a 3-D scanner, producing a second set of panels according to the scanned dimensional data, and finally filled the gaps between the first set of panels with the second set of panels, which are much smaller than the first set of panels, making the building process earlier and more accurate, which are difficult issues in building large tanks for liquefied natural gas.Type: ApplicationFiled: December 13, 2017Publication date: June 13, 2019Applicants: CHINA NATIONAL OFFSHORE OIL CORP., OFFSHORE OIL ENGINEERING CO., LTD., Tianjin UniversityInventors: Zhongzhi YE, Jing LU, Xiqiang ZHANG, Juan SU, Jian SU, Qing ZHANG, Yu SUN, Fudan ZHOU, Yu WANG, Wenduo HE
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Publication number: 20190178688Abstract: The present invention discloses a Fiber Bragg Grating demodulation device with a suppressed fluctuation at a variable ambient temperature and a demodulation method. The device comprises a broadband light source (1), an optical attenuator (2), a tunable F-P filter (3), a first optical fiber isolator (41), an erbium-doped optical fiber amplifier (5), an optical fiber first-stage beam splitter (6), a first optical fiber second-stage beam splitter (71), optical fiber circulators (8), FBG sensor arrays (9), a first photoelectric detector array (161), an optical fiber gas cell (10), a second optical fiber second-stage beam splitter (72), an optical fiber F-P etalon (11), a notch filter (12), an optical fiber assisted interferometer (13), a data acquisition card (17) and a processor (18).Type: ApplicationFiled: October 27, 2016Publication date: June 13, 2019Applicant: Tianjin UniversityInventors: Junfeng JIANG, Tiegen LIU, Jinling YAN, Kun LIU, Shuang WANG, Xuezhi ZHANG, Chuanjun ZANG, Renwei XIE, Qiliang CHU
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Publication number: 20190121048Abstract: The present invention discloses an optical fiber laying method by using Archimedes spiral in optical frequency domain reflection, wherein the optical fiber laying method comprises the following steps: performing two measurements continuously via a two-dimensional strain sensing device, and performing cross-correlation operation on the two one-dimensional information of the local distance domain, and obtaining the strain variation of the one-dimensional information corresponding to the two measurements from the obtained cross-correlation information; deriving the two-dimensional angle information and curvature radius information of the plane to be measured corresponding to one-dimensional information in the local distance domain based on Archimedes spiral formula; deriving the position coordinates corresponding to the two-dimensional plane based on the curvature radius information and two-dimensional angle information; corresponding the strain variation of the one-dimensional information to the position coordiType: ApplicationFiled: October 26, 2016Publication date: April 25, 2019Applicant: Tianjin UniversityInventors: Tiegen LIU, Zhenyang DING, Di YANG, Kun LIU, Junfeng JIANG, Zhexi XU
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Publication number: 20190108600Abstract: The present invention discloses an optimized operation method in micro-grid with multi-agent structure, which comprises the following steps: the main grid obtains the electricity market purchase price Pbuy which is to be sold to the user and DER selling price Psell at next stage after connected to the main grid; the DERs perform calculation of the optimized operation in the micro-grid based on bidding; the DERs of the micro-grid adopt bidding unit for quotation; and the bidding management Agent assists in completing the coordination and optimization of the units in the micro-grid; the bidding management multi-agent transmits the bidding results of each unit to the control system of the micro-grid, and the micro-grid performs optimized operation in micro-grid based on the coordinated bidding results.Type: ApplicationFiled: April 26, 2015Publication date: April 11, 2019Applicant: Tianjin UniversityInventors: Xiangyu KONG, Shengchen WANG
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Patent number: 10246650Abstract: The present invention provides a catalytic cracking fractionation and absorption-stabilization system, and energy saving method thereof; the present invention is to arrange a waste heat refrigerator of the main fractionating tower, a waste heat refrigerator of rich gas and a waste heat refrigerator of stabilizer in a catalytic cracking fractionation and absorption-stabilization system so as to utilize low temperature waste heat at the top of a main fractionating tower, rich gas, stable gasoline, intermediate heat exchange flow of an absorber of the system as a refrigerator driving heat source; in order to cool naphtha and circulating gasoline to a low temperature lower than 40° C., control low temperature operations of the absorber and reduce the heat load of a desorber and a stabilizer, and the heat extracted by the refrigerators is cooled by cooling water with a higher temperature so as to reduce the consumption of the cooling water.Type: GrantFiled: December 12, 2014Date of Patent: April 2, 2019Assignees: Tianjin University, Pei- Yang National Distillation Technology Corporation LimitedInventors: Hong Sui, Zhen Han, Xingang Li, Jingyi Li
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Patent number: 10247050Abstract: A multi-energy-form output energy tower for stepwise recovering waste heat of a gas engine, comprising an internal combustion engine (1), wherein the present invention also comprises a steam Rankine cycle system (2) which is capable of heat exchanging with the high temperature exhaust exhausted from the IC engine (1) to make the steam turbine (22) do expansion work. An organic Rankine cycle system which is respectively heat exchanged with high temperature exhaust, jacket water and charge air which are exhausted from the IC engine (1), and with condensation heat in the steam Rankine cycle system (2) to do expansion work; a lithium bromide refrigerator (4) which uses jacket waterpart of jacket water discharged from the IC engine (1) as a heat source of the absorption cooling system for heat exchange; and a hot water heat exchanger (5) connected with a high temperature exhaust of the IC engine (1) for heating domestic water.Type: GrantFiled: July 24, 2015Date of Patent: April 2, 2019Assignee: Tianjin UniversityInventors: Gequn Shu, Xuan Wang, Hua Tian, Jiaqiang Che, Peng Liu
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Patent number: 10235341Abstract: Method for solving the decomposition-coordination calculation based on Block Bordered Diagonal Form (BBDF) model by using data center. During the solving process, partitioning the electric power system network by using the existing network partitioning method to achieve the grid partition, and setting the parameters of virtual memories firstly, thus to establish the bin-packing model with the priority of energy efficiency; and then, setting each calculating step of the decomposition-coordination calculation based on BBDF as a task. Through the manners that servers host VMs and VMs map tasks, the decomposition-coordination algorithm can be executed in data center, and the running time and energy consumption of data center can be calculated. The calculating time of decomposition-coordination algorithm is shortened and the energy consumption in data center.Type: GrantFiled: September 22, 2014Date of Patent: March 19, 2019Assignee: Tianjin UniversityInventors: Ting Yang, Wenping Xiang, Yingmin Feng, Haibo Pen, Mingyu Xu, Jinkuo You, Hongtao Wang
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Publication number: 20190011253Abstract: The present invention discloses a distributed device for simultaneously measuring strain and temperature based on optical frequency domain reflection, comprising a tunable laser, a 1:99 beam splitter, a main interferometer system, a light source phase monitoring system based on an auxiliary interferometer, an acquisition device and a computer processing unit, wherein the main interferometer system comprises two Mach-Zehnder interferometers, and two optical fibers having different cladding diameters are arranged in parallel as sensing fibers. Due to the difference in temperature and strain coefficients of optical fibers of the same diameter, the temperature and strain values during changing the temperature and strain simultaneously can be obtained by matrix operation, thereby achieving an effect of eliminating cross sensitivity of temperature and strain sensing in optical frequency domain reflection.Type: ApplicationFiled: October 27, 2016Publication date: January 10, 2019Applicant: Tianjin UniversityInventors: Zhenyang DING, Di YANG, Tiegen LIU, Yang DU, Zhexi XU, Kun LIU, Junfeng JIANG