Patents Assigned to Toagosei Co., Ltd.
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Publication number: 20120122210Abstract: A method for transferring a foreign substance includes the steps of: preparing a construct for transferring a foreign substance that contains a carrier peptide fragment including either the amino acid sequence KKRTLRKNDRKKR (SEQ ID NO. 1) or an amino acid sequence formed by the substitution, deletion, and/or addition (insertion) of 1, 2, or 3 amino acid residues in the amino acid sequence, and a foreign substance of interest that is bonded to the N-terminus and/or C-terminus of the carrier peptide fragment; supplying the construct for transferring a foreign substance to a test sample that contains a target eukaryotic cell; and incubating the test sample that has been supplied with the construct for transferring a foreign substance to thereby transfer the construct into the eukaryotic cell in the test sample.Type: ApplicationFiled: July 28, 2010Publication date: May 17, 2012Applicant: TOAGOSEI CO. LTD.Inventors: Tetsuhiko Yoshida, Nahoko Kobayashi, Mikio Niwa
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Publication number: 20120122225Abstract: The method for transferring a foreign substance provided by the present invention includes the steps of: preparing a construct for transferring a foreign substance that contains a carrier peptide fragment including either the amino acid sequence WRRQARFK (SEQ ID NO. 1) or any amino acid sequence formed by the substitution, deletion, and/or addition (insertion) of 1, 2, or 3 amino acid residues in the amino acid sequence, and a foreign substance of interest that is bonded to the N-terminus and/or C-terminus of the carrier peptide fragment; supplying the construct for transferring a foreign substance to a test sample that contains a target eukaryotic cell; and incubating the test sample that has been supplied with the construct for transferring a foreign substance to thereby transfer the construct into the eukaryotic cell in the test sample.Type: ApplicationFiled: July 28, 2010Publication date: May 17, 2012Applicant: TOAGOSEI CO. LTD.Inventors: Nahoko Kobayashi, Tetsuhiko Yoshida, Mikio Niwa, Kenichi Tanaka
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Patent number: 8168739Abstract: The present invention has an object to provide a polysiloxane which is a liquid substance having low viscosity, is excellent in curing workability, and has excellent heat resistance in an obtained cured material, and to a production method of a cured material using the polysiloxane. Specifically disclosed is a polysiloxane which is obtained by hydrolysis and polycondensation of a silicon compound having three hydrolyzable groups, a silicon compound having two hydrolyzable groups and a silicon compound having one hydrolyzable group, and is characterized by containing a hydrosilylatable carbon-carbon unsaturated group, a hydrosilyl group and an alkoxysilyl group, and having a number average molecular weight of 500 to 20,000.Type: GrantFiled: November 13, 2008Date of Patent: May 1, 2012Assignee: Toagosei Co., Ltd.Inventors: Akinori Kitamura, Hiroshi Suzuki
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Publication number: 20120094115Abstract: A coating composition has excellent application workability, facilitates thick coating, rarely causes cracks at an initial drying stage, and provides a dried film having excellent tensile properties and adhesiveness. The composition contains an aggregate and an emulsion with a polymer particle dispersed in an aqueous medium. The polymer particle includes 40% to 98% of a unit formed by polymerizing an alkyl(meth)acrylate monomer, the alkyl group having 4 to 14 carbon atoms, 0.1% to 5% of a unit formed by polymerizing an ethylenically unsaturated carboxylic acid monomer, 1% to 20% of a unit formed by polymerizing a vinyl monomer having a cyano group, 1% to 20% of a unit formed by polymerizing a reaction product of a (meth)acrylic acid and a monofunctional epoxy compound, and 0% to 50% of a unit formed by copolymerizing at least one of the above monomers with another monomer.Type: ApplicationFiled: June 30, 2010Publication date: April 19, 2012Applicant: TOAGOSEI CO., LTD.Inventors: Shinji Takeda, Masafumi Achiwa, Hiroyuki Noguchi, Akemi Kouketsu, Katsunobu Mochizuki
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Patent number: 8138146Abstract: Disclosed is an antiviral agent comprising a non-naturally occurring, artificially synthesized peptide as the main ingredient. The antiviral agent comprises an antiviral peptide, wherein the antiviral peptide has at least one unit of an amino acid sequence constituted by at least five contiguous amino acid residues (which is known as a nuclear localization sequence (NLS)) or an amino acid sequence having a partial modification in the NLS and also having at least one unit of an amino acid sequence constituted by at least five contiguous amino acid residues (which is known as a nuclear export sequence (NES)) or an amino acid sequence having a partial modification in the NES.Type: GrantFiled: February 28, 2007Date of Patent: March 20, 2012Assignee: Toagosei Co., LtdInventors: Tetsuhiko Yoshida, Nahoko Kobayashi, Takanori Sato
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Publication number: 20120048743Abstract: Disclosed is an electrolysis method, whereby sodium chloride concentration of an aqueous caustic soda solution formed through electrolysis in a two-chamber ion-exchange membrane sodium chloride electrolytic cell, which is equipped with a gas diffusion electrode as a cathode and divided into an anode chamber containing an anode and a cathode gas chamber containing the cathode that are partitioned by an ion-exchange membrane, is lowered. In a two-chamber ion-exchange membrane electrolytic cell (1) using a gas diffusion electrode (7), electrolysis is performed while reducing the pressure difference between the liquid pressure in the anode chamber and the gas pressure in the cathode gas chamber, i.e.Type: ApplicationFiled: April 15, 2010Publication date: March 1, 2012Applicants: CHLORINE ENGINEERS CORP., LTD, TOAGOSEI CO., LTD, KANEKA CORPORATIONInventors: Mikihito Sugiyama, Yukinori Iguchi, Kiyohito Asaumi
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Publication number: 20120035112Abstract: A neuronal differentiation inducer provided by the present invention contains an artificially synthesized peptide which includes an amino acid sequence constituting a signal peptide in amyloid precursor protein (APP), or a partial sequence of the amino acid sequence constituting this signal peptide.Type: ApplicationFiled: April 12, 2010Publication date: February 9, 2012Applicant: Toagosei Co., Ltd.Inventors: Tetsuhiko Yoshida, Nahoko Kobayashi
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Patent number: 8110205Abstract: The present invention is completed by finding that a silver ion-containing zirconium phosphate represented by the following formula (1) is excellent in heat resistance and chemical resistance, low in resin coloring and excellent in processability. AgaMbZrcHfd(PO4)3.nH2O??(1) wherein, in the formula (1), M is at least one ion selected from alkali metal ion, hydrogen ion and ammonium ion, a, b, c and d are positive numbers satisfying a+b+4(c+d)=9; c and d satisfy 1.75<(c+d)<2.25; and n is 0 or a positive number of not more than 2.Type: GrantFiled: October 5, 2007Date of Patent: February 7, 2012Assignee: Toagosei Co., Ltd.Inventor: Koji Sugiura
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Patent number: 8110613Abstract: Provided is a method for efficiently producing a cationically curable condensed silicon compound. There was an unsolved problem that, in a condensation reaction, an oxetanyl group is subjected to ring-opening under an acidic condition, while gelation is easily caused under an alkaline condition. It was found that a silicon compound (C) having an oxetanyl group can be obtained without causing gelation even at a high concentration by the present method including a first step of separately subjecting a silicon compound (A) having four siloxane bond-forming groups and a silicon compound (B) having an oxetanyl group to alcohol exchange reaction with 1-propanol and a second step of subjecting silicon compounds (AP) and (BP) undergone the first step to hydrolytic copolycondensation under an alkaline condition at a specific ratio.Type: GrantFiled: December 14, 2009Date of Patent: February 7, 2012Assignee: Toagosei Co., Ltd.Inventors: Sayaka Oike, Akinori Kitamura, Hiroshi Suzuki
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Publication number: 20120019403Abstract: A method for compressing a symbol sequence, wherein each symbol may have one out of three or more possible symbol values, said method comprises the steps of modifying the symbol sequence by replacing each run pair, which contains a first run of symbols of a most frequent symbol value and a second run of symbols of a second most frequent symbol value, by a further symbol value not comprised in the three or more possible symbol values, generating a binary sequence comprising all replaced run pairs and compression encoding the binary sequence and the modified symbol sequence.Type: ApplicationFiled: March 30, 2010Publication date: January 26, 2012Applicant: Toagosei Co., Ltd.Inventors: Qu Qing Chen, Kang Ying Cai, Zhi Bo Chen, Jun Teng
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Patent number: 8097263Abstract: The present invention provides a silver based inorganic antibacterial agent excellent in heat resistance and chemical resistance, lowered in resin coloring and excellent in processability. The present invention has been completed by finding out that problems can be solved by a silver ion-containing zirconium phosphate represented by the following general formula (1) which is produced by a wet synthesis under specific production conditions. AgaNabHc(H3O)dZreHff(PO4)3.nH2O??(1) wherein, in the formula (1), a, b, c, d, e and f are positive numbers satisfying 1.75<(e+f)<2.25 and a+b+c+d+4(e+f)=9; and n is not more than 2.Type: GrantFiled: October 5, 2007Date of Patent: January 17, 2012Assignee: Toagosei Co., Ltd.Inventors: Koji Sugiura, Takashi Suzuki
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Patent number: 8066810Abstract: The present invention provides a crystalline layered zirconium phosphate, which is an ion exchanger particle excellent in heat resistance and chemical resistance, and utilizable as an impurity ion trapping agent for electronic materials, a raw material for antibacterials, a deodorant, a discoloration inhibitor, a rust preventive and the like, and which is also excellent in various processabilities. As a result of exhaustive studies to solve the problems, the present inventor has found a novel layered zirconium phosphate represented by the general formula (1) shown below: Zr1-xHfxHa(PO4)b.nH2O??(1) wherein a and b are positive numbers satisfying 3b?a=4; b is a number satisfying 2<b?2.3; x is a positive number satisfying 0?x<1; and n is a positive number satisfying 0?n?2, and thus has achieved the present invention.Type: GrantFiled: October 15, 2007Date of Patent: November 29, 2011Assignee: Toagosei Co., Ltd.Inventor: Yasuharu Ono
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Patent number: 8058370Abstract: The object of the present invention is to provide a process for producing high-quality polymer microparticles having uniform particle size of the order of several micrometers to tens of micrometers by inverse suspension polymerization at high productivity while keeping excellent dispersion stability without causing aggregation among particles. The process is one for the production of polymer microparticles by inverse suspension polymerization of a vinyl monomer and includes steps of preparing in a dispersing tank a water-in-oil (W/O) type emulsion in which an organic solvent is a continuous phase and an aqueous solution of a vinyl-based monomer is a dispersing phase, and conducting the inverse suspension polymerization while feeding the water-in-oil (W/O) type emulsion to a continuous stirred tank reactor.Type: GrantFiled: January 22, 2009Date of Patent: November 15, 2011Assignee: Toagosei Co., Ltd.Inventors: Shinji Hibino, Hideo Matsuzaki, Akihiro Gotou
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Publication number: 20110251318Abstract: An adhesive composition is provided particularly excellent in thermal shock resistance for adhesive strength as well as high shear adhesive strength, peel adhesive strength and impact adhesive strength. The adhesive composition of the present invention contains (a) a 2-cyanoacrylate such as 2-ethoxyethyl 2-cyanoacrylate and (b) a polyfunctional cyanoacrylate having two or more 2-cyanoacryloyl groups, the number average molecular weight of the polyfunctional cyanoacrylate (b) is in the range from 1,000 to 50,000, and preferably from 2,000 to 30,000, and the content of the polyfunctional cyanoacrylate (b) is in the range from 1 to 400 parts by weight, and preferably from 1 to 200 parts by weight based on 100 parts by weight of the 2-cyanoacrylate (a).Type: ApplicationFiled: December 22, 2009Publication date: October 13, 2011Applicant: TOAGOSEI CO., LTD.Inventors: Kenichi Ishizaki, Muneaki Kano
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Publication number: 20110245448Abstract: Provided is a method for efficiently producing a cationically curable condensed silicon compound. There was an unsolved problem that, in a condensation reaction, an oxetanyl group is subjected to ring-opening under an acidic condition, while gelation is easily caused under an alkaline condition. It was found that a silicon compound (C) having an oxetanyl group can be obtained without causing gelation even at a high concentration by the present method including a first step of separately subjecting a silicon compound (A) having four siloxane bond-forming groups and a silicon compound (B) having an oxetanyl group to alcohol exchange reaction with 1-propanol and a second step of subjecting silicon compounds (AP) and (BP) undergone the first step to hydrolytic copolycondensation under an alkaline condition at a specific ratio.Type: ApplicationFiled: December 14, 2009Publication date: October 6, 2011Applicant: TOAGOSEI CO., LTD.Inventors: Sayaka Oike, Akinori Kitamura, Hiroshi Suzuki
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Patent number: 8017661Abstract: A bismuth compound, useful as an inorganic anion exchanger used for an encapsulating material for, e.g., semiconductors, has a peak intensity of 900 to 2000 cps at 2?=27.9° to 28.1° and a peak intensity of 100 to 800 cps at 2?=8.45° to 8.55° in a powder X-ray diffraction pattern, and is represented by the following formula (1): Bi(OH)x(NO3)y.nH2O??(1) wherein x is a positive number not less than 2.5 and less than 3, y is a positive number not more than 0.5, x+y=3, and n is 0 or a positive number.Type: GrantFiled: November 16, 2007Date of Patent: September 13, 2011Assignee: Toagosei Co., Ltd.Inventor: Yasuharu Ono
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Patent number: 7985831Abstract: An epitope peptide is provided, which is capable of binding specifically to an antibody characteristic of Crohn's disease that is specifically observed in patients with Crohn's disease, together with a test method for conveniently and rapidly determining whether a subject is affected by Crohn's disease by use of the above peptide. The epitope peptide to the Crohn's disease antibody comprises a peptide having an amino acid sequences represented by any one of SEQ ID NOS: 1 to 3 or a salt thereof. A test reagent and a test method for Crohn's disease are provided, which comprise the peptide as an active ingredient.Type: GrantFiled: April 26, 2005Date of Patent: July 26, 2011Assignees: Toagosei Co., Ltd., Kurume UniversityInventors: Mikio Niwa, Katsuhiko Matsuo, Keiichi Mitsuyama, Michio Sata
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Patent number: 7976807Abstract: Hexachlorodisilane is decomposed into hydrochloric acid, silicon dioxide and water by introducing hexachlorodisilane-containing flue gas into a reaction region without moistening the flue gas and by supplying oxygen-containing gas that also contains a small amount of moisture to the reaction region maintained at a temperature at which hexachlorodisilane decomposes.Type: GrantFiled: February 6, 2007Date of Patent: July 12, 2011Assignees: Kanken Techno Co., Ltd., Toagosei Co., Ltd.Inventors: Hiroshi Imamura, Hiroaki Takeuchi, Koji Ishikawa, Hiroshi Suzuki, Akira Moriya, Katsuyoshi Harada
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Publication number: 20110165389Abstract: The present invention is a method for forming a patterned electroconductive layer containing an electroconductive polymer on a surface of a base body and is characterized in that a positive type photoresist composition containing a naphthoquinone diazide and a novolak resin is used, and that a developer containing a potassium ion at a concentration of 0.08 mol/l to 0.20 mol/l, and a coexistent sodium ion at a concentration of less than 0.1 mol/l is used for development of a resist film obtained by the positive type photoresist composition.Type: ApplicationFiled: July 23, 2009Publication date: July 7, 2011Applicants: TOAGOSEI CO., LTD., TSURUMI SODA CO., LTD.Inventor: Hiromu Taguchi
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Patent number: 7967492Abstract: To provide a light diffusion film that contributes lightweight with reduction in thickness, a planar light source element utilizing the light diffusion film, and a liquid crystal display device utilizing the light diffusion film and/or the planar light source element. A light diffusion film (25) having a plurality of projections (23) of a specific shape is at least partly formed from a composition containing a mixture of a photocurable compound and a particulate material. A light guide plate (22), provided with one or more light sources (21) at one side face thereof, is bonded to vertexes of the projections (23) to provide a planar light source element, which is thin and lightweight and capable of emitting non-glaring light uniformly from the entire surface thereof.Type: GrantFiled: February 27, 2006Date of Patent: June 28, 2011Assignees: Kuraray Co., Ltd., Toagosei Co., Ltd.Inventors: Atsushi Nagasawa, Yasuyuki Sanai