Patents Assigned to TOKYO UNIVERSITY OF SCIENCE FOUNDATION
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Publication number: 20170176403Abstract: Provided is a hydrogen concentration measuring device capable of measuring with high accuracy a hydrogen concentration over an extensive range by a simple configuration. The device includes: a sensor chip which detects the electric resistance of a sensing film; an optical measurement unit which detects the transmitted light intensity of the film; and a controller. The controller performs measurement processing such that a hydrogen concentration in the gas atmosphere is measured based on the detected electric resistance in a first measurement range and based on the detected transmitted light intensity in a second measurement range and is determined so as to reduce a difference between the hydrogen concentration based on the detected electric resistance and the hydrogen concentration based on the detected transmitted light intensity in the overlap of the first measurement range and the second measurement range.Type: ApplicationFiled: December 16, 2016Publication date: June 22, 2017Applicants: STANLEY ELECTRIC CO., LTD., TOKYO UNIVERSITY OF SCIENCE FOUNDATIONInventors: Koji MATSUMOTO, Masakazu SATSU, Takanori AIMONO, Keiichi IKEGAMI, Shinichi UOZUMI, Keishi NISHIO, Yuki YAMAGUCHI
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Publication number: 20170137782Abstract: It is an object of the present invention to provide a method for easily producing an antigen-specific B cell population comprising IgG-positive B cells specific to a specific antigen. The present invention provides a method for producing a B cell population, comprising culturing B cells, in which the expression of a Bach2 gene has been increased, in the presence of a means for acting on CD40 and/or a BAFF receptor.Type: ApplicationFiled: June 30, 2015Publication date: May 18, 2017Applicants: TOKYO UNIVERSITY OF SCIENCE FOUNDATION, KANEKA CORPORATIONInventors: Daisuke KITAMURA, Tomoyuki NAKAISHI
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Patent number: 9599454Abstract: An optical interferometer includes: a light source that emits a coherent first beam and a second beam that has a frequency difference corresponding to the natural frequency of a target molecule; amplitude modulating means that modulates the amplitude of the second beam; splitting means that splits the first beam into a reference beam and a first applied beam; optical path length adjusting means that adjusts the optical path length of the reference beam; and detecting means that detects an interference pattern between the reference beam and the first beam (a signal beam) that has experienced a stimulated Raman loss or gain in accordance with the amplitude modulation as a result of the frequency difference resonating with the target molecule when the first applied beam and a second applied beam (the amplitude modulated second beam) have been applied to a measurement position of an object.Type: GrantFiled: September 27, 2012Date of Patent: March 21, 2017Assignee: TOKYO UNIVERSITY OF SCIENCE FOUNDATIONInventor: Hiroharu Yui
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Patent number: 9575363Abstract: In a liquid crystal display device 1 including a liquid crystal cell 2 having a liquid crystal layer, a first polarization plate 3 and a second polarization plate 4, and an optical compensation plate 5, when a differential coefficient of the amount of transmitted light I1 with respect to a time t when the driving voltage is turned off from on in a case in which the optical compensation plate 5 is not disposed is represented by ?I1/?t, and a differential coefficient of the amount of transmitted light I2 with respect to the time t when the driving voltage is turned off from on in a case in which the optical compensation plate 5 is disposed is represented by ?I2/?t, a phase difference in the liquid crystal layer and a phase difference in the optical compensation plate 5 are optically designed to satisfy a relationship of |?I2/?t|>|?I1/?t|.Type: GrantFiled: August 4, 2014Date of Patent: February 21, 2017Assignees: TOKYO UNIVERSITY OF SCIENCE FOUNDATION, DIC CORPORATIONInventors: Shunsuke Kobayashi, Kiyofumi Takeuchi, Masakazu Kaneoya
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Publication number: 20170040612Abstract: It is an object of the present invention to provide an electrode having superior charge-discharge capacity, even in the case of using an active material containing silicon.Type: ApplicationFiled: April 21, 2015Publication date: February 9, 2017Applicants: WAKO PURE CHEMICAL INDUSTRIES, LTD., TOKYO UNIVERSITY OF SCIENCE FOUNDATIONInventors: Shinichi Komaba, Kiyofumi Yamagiwa, Shoko Aoki, Kuniaki Okamoto, Takahiro Kiyosu, Yasuyoshi Mori, Takatoshi Matsuura, Michihiko Sato
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Publication number: 20170028065Abstract: The purpose of the present invention is to provide an anticancer agent for potentiating an antitumor effect, alleviating side effects, and further extending the survival rate by concomitant use with a component having an anticancer effect. An anticancer agent combining arctigenin and a component other than arctigenin that has an anticancer effect, in which the anticancer agent may be a combination drug or may be a kit configured from a formulation containing arctigenin and a formulation containing a component that has an anticancer effect, and the concomitant use of arctigenin and the component having an anticancer effect more strongly inhibits tumor growth and reduces the proportion of cancer stem cells in the tumor, making it possible to extend the total survival time and to alleviate side effects caused by the component having an anticancer effect.Type: ApplicationFiled: April 10, 2015Publication date: February 2, 2017Applicants: National University Corporation University of Toyama, Kracie Pharma, Ltd., National Cancer Center, Tokyo University of Science FoundationInventors: Hiroyasu Esumi, Kouji IKEDA, Katsuya TSUCHIHARA, Shigeki Chiba, Satoshi Yomoda, Takanori Kawashima, Toshiki Okubo, Yasuhiro TEZUKA, Kenta MURATA
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Patent number: 9515596Abstract: A switched reluctance motor includes: a stator provided with a plurality of stator teeth as salient poles in a radial fashion with winding wire wound around each of the plurality of stator teeth; a rotor provided with a plurality of rotor teeth as salient poles in a radial fashion; a driving circuit configured to apply a current to the winding wire for each phase; and a control device configured to control the driving circuit, the control device being configured to perform: starting rising of a current to the winding wire of a stator tooth of a phase being a non-excitation target due to stop of energization to the winding wire; and allowing the current applied to the winding wire of the stator tooth of a phase being an excitation target to fall.Type: GrantFiled: July 17, 2015Date of Patent: December 6, 2016Assignees: TOYOTA JIDOSHA KABUSHIKI KAISHA, TOKYO UNIVERSITY OF SCIENCE FOUNDATIONInventors: Jun-ichi Deguchi, Kazuya Arakawa, Kensuke Yoshizue, Nobukazu Hoshi, Noboru Nakayama, Takuya Iguchi
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Patent number: 9513295Abstract: The present invention provides a method for detecting an interaction, which method can solve not only the problem of false negatives but also the problem of false positives.Type: GrantFiled: September 28, 2012Date of Patent: December 6, 2016Assignee: TOKYO UNIVERSITY OF SCIENCE FOUNDATIONInventors: Etsuko Miyamoto, Shigeo Fujimori
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Publication number: 20160329881Abstract: An amplifying circuit according to an embodiment includes a sample and hold circuit, an operational amplifier, a feedback capacitance, and a level shift circuit. The sample and hold circuit includes a sampling capacitance to sample an analog input signal in a sampling phase. The operational amplifier amplifies and outputs the analog input signal held by the sampling capacitance in the amplifying phase. The feedback capacitance is connected between the input terminal of the operational amplifier and the analog output terminal. The level shift circuit includes a level shift capacitance to sample the analog input signal in the sampling phase. A plurality of level shift capacitances is provided and connected in cascade between the output terminal of the operational amplifier and the analog output terminal.Type: ApplicationFiled: March 4, 2016Publication date: November 10, 2016Applicants: KABUSHIKI KAISHA TOSHIBA, Tokyo University of Science FoundationInventors: Junya MATSUNO, Masanori FURUTA, Tetsuro ITAKURA, Akira HYOGO, Tatsuji MATSUURA, Takuya HARA
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Patent number: 9481882Abstract: A method for analyzing biomolecular interactions, which method can be carried out without performing affinity selection using an immobilized bait, is provided. mRNA portions of assignment molecules that interacted with each other are linked together by annealing via a DNA linker for linking mRNA portions of assignment molecules together, the DNA linker comprising, at the 5?-end, an mRNA-complementary region complementary to a sequence at the 5?-end of each mRNA portion, and, at the 3?-end, a self-complementary region complementary between molecules of the DNA linker, the DNA linker being phosphorylated at the 5?-end.Type: GrantFiled: March 31, 2011Date of Patent: November 1, 2016Assignee: TOKYO UNIVERSITY OF SCIENCE FOUNDATIONInventors: Etsuko Miyamoto, Toru Tsuji, Shigeo Fujimori, Masamichi Ishizaka
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Patent number: 9473061Abstract: A switched reluctance motor includes: a stator provided with a plurality of stator teeth as salient poles in a radial fashion with winding wire wound around each of the plurality of stator teeth; a rotor provided with a plurality of rotor teeth as salient poles in a radial fashion; a driving circuit configured to apply a current to the winding wire for each phase; and a control device configured to control the driving circuit, the control device being configured to perform: starting rising of a current to the winding wire of a stator tooth of a phase being a non-excitation target due to stop of energization to the winding wire; and allowing the current applied to the winding wire of the stator tooth of a phase being an excitation target to fall.Type: GrantFiled: July 17, 2015Date of Patent: October 18, 2016Assignees: TOYOTA JIDOSHA KABUSHIKI KAISHA, TOKYO UNIVERSITY OF SCIENCE FOUNDATIONInventors: Jun-ichi Deguchi, Kazuya Arakawa, Kensuke Yoshizue, Nobukazu Hoshi, Noboru Nakayama, Takuya Iguchi
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Publication number: 20160187698Abstract: In a liquid crystal display device 1 including a liquid crystal cell 2 having a liquid crystal layer, a first polarization plate 3 and a second polarization plate 4, and an optical compensation plate 5, when a differential coefficient of the amount of transmitted light I1 with respect to a time t when the driving voltage is turned off from on in a case in which the optical compensation plate 5 is not disposed is represented by ?I1/?t, and a differential coefficient of the amount of transmitted light I2 with respect to the time t when the driving voltage is turned off from on in a case in which the optical compensation plate 5 is disposed is represented by ?I2/?t, a phase difference in the liquid crystal layer and a phase difference in the optical compensation plate 5 are optically designed to satisfy a relationship of |?I2/?t|>|?I1/?t.Type: ApplicationFiled: August 4, 2014Publication date: June 30, 2016Applicants: TOKYO UNIVERSITY OF SCIENCE FOUNDATION, DIC CORPORATIONInventors: Shunsuke Kobayashi, Kiyofumi Takeuchi, Masakazu Kaneoya
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Publication number: 20160122644Abstract: The present invention provides a method of uniformizing output light from a liquid crystal display element and a liquid crystal display element in which output light is uniformized. The method of uniformizing output light of a liquid crystal display element includes: using a composition containing nanoparticles with an average particle diameter of 1 nm to 100 nm as a liquid crystal composition included in a liquid crystal layer in the liquid crystal display element having the liquid crystal layer interposed between a pair of substrates, and uniformizing light output from the liquid crystal display element. The present invention also provides a liquid crystal display element obtained by applying the method of uniformizing output light.Type: ApplicationFiled: October 27, 2015Publication date: May 5, 2016Applicants: TOKYO UNIVERSITY OF SCIENCE FOUNDATION, DIC CORPORATIONInventors: Shunsuke Kobayashi, Yukihide Shiraishi, Naoki Toshima, Mitsuhiro Akimoto, Kenzo Takeishi, Haruyoshi Takatsu, Kunihiko Kotani
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BASE GENERATOR, BASE-REACTIVE COMPOSITION CONTAINING SAID BASE GENERATOR, AND BASE GENERATION METHOD
Publication number: 20160122292Abstract: It is a subject of the present invention to provide a base generator which has high solubility to general-purpose organic solvents, can dissolve directly into a base-reactive compound, such as an epoxy-based compound, further is provided with both performance of high heat resistance and low nucleophilicity, and generates a strong base, a base-reactive composition comprising the base generator and a base-reactive compound, as well as a method for generating a base, etc. The present invention relates to a compound represented by the general formula (A), a base generator comprising the compound, a base-reactive composition which comprises the base generator and a base-reactive compound, as well as a method for generating a base, etc.Type: ApplicationFiled: June 25, 2014Publication date: May 5, 2016Applicant: TOKYO UNIVERSITY OF SCIENCE FOUNDATIONInventors: Nobuhiko SAKAI, Kosuke YANABA, Koji ARIMITSU -
Patent number: 9327013Abstract: An activity enhancer for an anticancer agent includes, as an active ingredient, a D-form amino acid residue-containing FNIII14 polypeptide, the D-form amino acid residue-containing FNIII14 being a polypeptide FNIII14 represented by SEQ ID NO: 1 in which at least one of amino acid residues at positions 1 to 13 is a D-form amino acid residue. An anticancer composition includes the activity enhancer for an anticancer agent and an anticancer agent.Type: GrantFiled: March 9, 2012Date of Patent: May 3, 2016Assignees: TOKYO UNIVERSITY OF SCIENCE FOUNDATION, SAGA UNIVERSITY, NATIONAL UNIVERSITY CORPORATION KAGAWA UNIVERSITYInventors: Fumio Fukai, Hiroaki Kodama, Takuya Matsunaga
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Patent number: 9332651Abstract: The invention provides is a process for producing a structure (22) with a metal film, including the steps of preparing a mother die (10) in which a first metal film (16) is formed on the surface of a base (12) on which a concave and convex pattern (14) is formed, forming a second metal film (18) on the first metal film (16), adhering a support member (20) to the second metal film (18), and separating the second metal film (18) to which the concave and convex pattern has been transferred to the second metal film (18) together with the support member from the first metal film (16). Preferably, the first metal film (16) is a film containing Cr and Al, and the second metal film (18) is a film containing at least one metal selected from the group consisting of Au, Ag, Cu, Al, and Pt.Type: GrantFiled: February 9, 2009Date of Patent: May 3, 2016Assignee: TOKYO UNIVERSITY OF SCIENCE FOUNDATIONInventor: Jun Taniguchi
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Publication number: 20160043681Abstract: A switched reluctance motor includes: a stator provided with a plurality of stator teeth as salient poles in a radial fashion with winding wire wound around each of the plurality of stator teeth; a rotor provided with a plurality of rotor teeth as salient poles in a radial fashion; a driving circuit configured to apply a current to the winding wire for each phase; and a control device configured to control the driving circuit, the control device being configured to perform: starting rising of a current to the winding wire of a stator tooth of a phase being a non-excitation target due to stop of energization to the winding wire; and allowing the current applied to the winding wire of the stator tooth of a phase being an excitation target to fall.Type: ApplicationFiled: July 17, 2015Publication date: February 11, 2016Applicants: Toyota Jidosha Kabushiki Kaisha, Tokyo University of Science FoundationInventors: Jun-ichi DEGUCHI, Kazuya ARAKAWA, Kensuke YOSHIZUE, Nobukazu HOSHI, Noboru NAKAYAMA, Takuya IGUCHI
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Patent number: 9233017Abstract: A lower back assistance apparatus including: a back frame 14 mounted to the back of a user and capable of movement following a user tilting forward; shoulder straps 22 that are attached to a back mounting section and extend towards the user trunk forward side for supporting the trunk of a user from the forward side; thigh plates 18 for mounting to the front of lower limbs of the user; coupling frames 20 with one end coupled to the thigh plates 18 and the other end coupled to the back frame 14 by joint sections 16 so as to allow relative movement with respect to the back frame 14, and capable of maintaining a non-bent profile during the relative movement; and actuators 40 that in an actuated state prevent the back frame 14 from tilting in the user forward direction.Type: GrantFiled: March 4, 2010Date of Patent: January 12, 2016Assignee: TOKYO UNIVERSITY OF SCIENCE FOUNDATIONInventors: Hiroshi Kobayashi, Takuya Hashimoto, Yutaka Sato, Eiji Ishowata, Keita Suzuki, Hiroyuki Kobayashi, Kouhei Yamamoto
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Publication number: 20160002364Abstract: A growth enhancer for Lactobacillus murinus, Lactobacillus salivarius, or a bacterium that belongs to the genus Lactobacillus and that has a homology of 16S rDNA of 90% or higher with Lactobacillus murinus or Lactobacillus salivarius includes a ?-glucan having a molecular weight of from 0.2 K to 50 K. A regulatory T-cell number increasing agent, a method of enhancing growth of a lactic acid bacterium, a method of increasing the number of regulatory T-cells, a method of evaluating a regulatory T-cell number increasing effect, and a method of evaluating a growth enhancing effect on a lactic acid bacterium are also provided.Type: ApplicationFiled: March 10, 2014Publication date: January 7, 2016Applicant: TOKYO UNIVERSITY OF SCIENCE FOUNDATIONInventors: Yoichiro Iwakura, Ce Tang, Naohito Ohno
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Publication number: 20150287993Abstract: It is an object of the present invention to provide an electrode capable of maintaining superior capacity retention without destruction of an electrode structure, even in the case of using an active material including silicon.Type: ApplicationFiled: October 25, 2013Publication date: October 8, 2015Applicants: WAKO PURE CHEMICAL INDUSTRIES, LTD., Tokyo University of Science FoundationInventors: Shinichi Komaba, Naoaki Yabuuchi, Zhen-Ji Han, Takeo Sasaki, Shota Hashimoto, Kuniaki Okamoto, Tsuneaki Maesawa