Patents Assigned to TOKYO UNIVERSITY OF SCIENCE FOUNDATION
  • Publication number: 20170176403
    Abstract: Provided is a hydrogen concentration measuring device capable of measuring with high accuracy a hydrogen concentration over an extensive range by a simple configuration. The device includes: a sensor chip which detects the electric resistance of a sensing film; an optical measurement unit which detects the transmitted light intensity of the film; and a controller. The controller performs measurement processing such that a hydrogen concentration in the gas atmosphere is measured based on the detected electric resistance in a first measurement range and based on the detected transmitted light intensity in a second measurement range and is determined so as to reduce a difference between the hydrogen concentration based on the detected electric resistance and the hydrogen concentration based on the detected transmitted light intensity in the overlap of the first measurement range and the second measurement range.
    Type: Application
    Filed: December 16, 2016
    Publication date: June 22, 2017
    Applicants: STANLEY ELECTRIC CO., LTD., TOKYO UNIVERSITY OF SCIENCE FOUNDATION
    Inventors: Koji MATSUMOTO, Masakazu SATSU, Takanori AIMONO, Keiichi IKEGAMI, Shinichi UOZUMI, Keishi NISHIO, Yuki YAMAGUCHI
  • Publication number: 20170137782
    Abstract: It is an object of the present invention to provide a method for easily producing an antigen-specific B cell population comprising IgG-positive B cells specific to a specific antigen. The present invention provides a method for producing a B cell population, comprising culturing B cells, in which the expression of a Bach2 gene has been increased, in the presence of a means for acting on CD40 and/or a BAFF receptor.
    Type: Application
    Filed: June 30, 2015
    Publication date: May 18, 2017
    Applicants: TOKYO UNIVERSITY OF SCIENCE FOUNDATION, KANEKA CORPORATION
    Inventors: Daisuke KITAMURA, Tomoyuki NAKAISHI
  • Patent number: 9599454
    Abstract: An optical interferometer includes: a light source that emits a coherent first beam and a second beam that has a frequency difference corresponding to the natural frequency of a target molecule; amplitude modulating means that modulates the amplitude of the second beam; splitting means that splits the first beam into a reference beam and a first applied beam; optical path length adjusting means that adjusts the optical path length of the reference beam; and detecting means that detects an interference pattern between the reference beam and the first beam (a signal beam) that has experienced a stimulated Raman loss or gain in accordance with the amplitude modulation as a result of the frequency difference resonating with the target molecule when the first applied beam and a second applied beam (the amplitude modulated second beam) have been applied to a measurement position of an object.
    Type: Grant
    Filed: September 27, 2012
    Date of Patent: March 21, 2017
    Assignee: TOKYO UNIVERSITY OF SCIENCE FOUNDATION
    Inventor: Hiroharu Yui
  • Patent number: 9575363
    Abstract: In a liquid crystal display device 1 including a liquid crystal cell 2 having a liquid crystal layer, a first polarization plate 3 and a second polarization plate 4, and an optical compensation plate 5, when a differential coefficient of the amount of transmitted light I1 with respect to a time t when the driving voltage is turned off from on in a case in which the optical compensation plate 5 is not disposed is represented by ?I1/?t, and a differential coefficient of the amount of transmitted light I2 with respect to the time t when the driving voltage is turned off from on in a case in which the optical compensation plate 5 is disposed is represented by ?I2/?t, a phase difference in the liquid crystal layer and a phase difference in the optical compensation plate 5 are optically designed to satisfy a relationship of |?I2/?t|>|?I1/?t|.
    Type: Grant
    Filed: August 4, 2014
    Date of Patent: February 21, 2017
    Assignees: TOKYO UNIVERSITY OF SCIENCE FOUNDATION, DIC CORPORATION
    Inventors: Shunsuke Kobayashi, Kiyofumi Takeuchi, Masakazu Kaneoya
  • Publication number: 20170040612
    Abstract: It is an object of the present invention to provide an electrode having superior charge-discharge capacity, even in the case of using an active material containing silicon.
    Type: Application
    Filed: April 21, 2015
    Publication date: February 9, 2017
    Applicants: WAKO PURE CHEMICAL INDUSTRIES, LTD., TOKYO UNIVERSITY OF SCIENCE FOUNDATION
    Inventors: Shinichi Komaba, Kiyofumi Yamagiwa, Shoko Aoki, Kuniaki Okamoto, Takahiro Kiyosu, Yasuyoshi Mori, Takatoshi Matsuura, Michihiko Sato
  • Publication number: 20170028065
    Abstract: The purpose of the present invention is to provide an anticancer agent for potentiating an antitumor effect, alleviating side effects, and further extending the survival rate by concomitant use with a component having an anticancer effect. An anticancer agent combining arctigenin and a component other than arctigenin that has an anticancer effect, in which the anticancer agent may be a combination drug or may be a kit configured from a formulation containing arctigenin and a formulation containing a component that has an anticancer effect, and the concomitant use of arctigenin and the component having an anticancer effect more strongly inhibits tumor growth and reduces the proportion of cancer stem cells in the tumor, making it possible to extend the total survival time and to alleviate side effects caused by the component having an anticancer effect.
    Type: Application
    Filed: April 10, 2015
    Publication date: February 2, 2017
    Applicants: National University Corporation University of Toyama, Kracie Pharma, Ltd., National Cancer Center, Tokyo University of Science Foundation
    Inventors: Hiroyasu Esumi, Kouji IKEDA, Katsuya TSUCHIHARA, Shigeki Chiba, Satoshi Yomoda, Takanori Kawashima, Toshiki Okubo, Yasuhiro TEZUKA, Kenta MURATA
  • Patent number: 9515596
    Abstract: A switched reluctance motor includes: a stator provided with a plurality of stator teeth as salient poles in a radial fashion with winding wire wound around each of the plurality of stator teeth; a rotor provided with a plurality of rotor teeth as salient poles in a radial fashion; a driving circuit configured to apply a current to the winding wire for each phase; and a control device configured to control the driving circuit, the control device being configured to perform: starting rising of a current to the winding wire of a stator tooth of a phase being a non-excitation target due to stop of energization to the winding wire; and allowing the current applied to the winding wire of the stator tooth of a phase being an excitation target to fall.
    Type: Grant
    Filed: July 17, 2015
    Date of Patent: December 6, 2016
    Assignees: TOYOTA JIDOSHA KABUSHIKI KAISHA, TOKYO UNIVERSITY OF SCIENCE FOUNDATION
    Inventors: Jun-ichi Deguchi, Kazuya Arakawa, Kensuke Yoshizue, Nobukazu Hoshi, Noboru Nakayama, Takuya Iguchi
  • Patent number: 9513295
    Abstract: The present invention provides a method for detecting an interaction, which method can solve not only the problem of false negatives but also the problem of false positives.
    Type: Grant
    Filed: September 28, 2012
    Date of Patent: December 6, 2016
    Assignee: TOKYO UNIVERSITY OF SCIENCE FOUNDATION
    Inventors: Etsuko Miyamoto, Shigeo Fujimori
  • Publication number: 20160329881
    Abstract: An amplifying circuit according to an embodiment includes a sample and hold circuit, an operational amplifier, a feedback capacitance, and a level shift circuit. The sample and hold circuit includes a sampling capacitance to sample an analog input signal in a sampling phase. The operational amplifier amplifies and outputs the analog input signal held by the sampling capacitance in the amplifying phase. The feedback capacitance is connected between the input terminal of the operational amplifier and the analog output terminal. The level shift circuit includes a level shift capacitance to sample the analog input signal in the sampling phase. A plurality of level shift capacitances is provided and connected in cascade between the output terminal of the operational amplifier and the analog output terminal.
    Type: Application
    Filed: March 4, 2016
    Publication date: November 10, 2016
    Applicants: KABUSHIKI KAISHA TOSHIBA, Tokyo University of Science Foundation
    Inventors: Junya MATSUNO, Masanori FURUTA, Tetsuro ITAKURA, Akira HYOGO, Tatsuji MATSUURA, Takuya HARA
  • Patent number: 9481882
    Abstract: A method for analyzing biomolecular interactions, which method can be carried out without performing affinity selection using an immobilized bait, is provided. mRNA portions of assignment molecules that interacted with each other are linked together by annealing via a DNA linker for linking mRNA portions of assignment molecules together, the DNA linker comprising, at the 5?-end, an mRNA-complementary region complementary to a sequence at the 5?-end of each mRNA portion, and, at the 3?-end, a self-complementary region complementary between molecules of the DNA linker, the DNA linker being phosphorylated at the 5?-end.
    Type: Grant
    Filed: March 31, 2011
    Date of Patent: November 1, 2016
    Assignee: TOKYO UNIVERSITY OF SCIENCE FOUNDATION
    Inventors: Etsuko Miyamoto, Toru Tsuji, Shigeo Fujimori, Masamichi Ishizaka
  • Patent number: 9473061
    Abstract: A switched reluctance motor includes: a stator provided with a plurality of stator teeth as salient poles in a radial fashion with winding wire wound around each of the plurality of stator teeth; a rotor provided with a plurality of rotor teeth as salient poles in a radial fashion; a driving circuit configured to apply a current to the winding wire for each phase; and a control device configured to control the driving circuit, the control device being configured to perform: starting rising of a current to the winding wire of a stator tooth of a phase being a non-excitation target due to stop of energization to the winding wire; and allowing the current applied to the winding wire of the stator tooth of a phase being an excitation target to fall.
    Type: Grant
    Filed: July 17, 2015
    Date of Patent: October 18, 2016
    Assignees: TOYOTA JIDOSHA KABUSHIKI KAISHA, TOKYO UNIVERSITY OF SCIENCE FOUNDATION
    Inventors: Jun-ichi Deguchi, Kazuya Arakawa, Kensuke Yoshizue, Nobukazu Hoshi, Noboru Nakayama, Takuya Iguchi
  • Publication number: 20160187698
    Abstract: In a liquid crystal display device 1 including a liquid crystal cell 2 having a liquid crystal layer, a first polarization plate 3 and a second polarization plate 4, and an optical compensation plate 5, when a differential coefficient of the amount of transmitted light I1 with respect to a time t when the driving voltage is turned off from on in a case in which the optical compensation plate 5 is not disposed is represented by ?I1/?t, and a differential coefficient of the amount of transmitted light I2 with respect to the time t when the driving voltage is turned off from on in a case in which the optical compensation plate 5 is disposed is represented by ?I2/?t, a phase difference in the liquid crystal layer and a phase difference in the optical compensation plate 5 are optically designed to satisfy a relationship of |?I2/?t|>|?I1/?t.
    Type: Application
    Filed: August 4, 2014
    Publication date: June 30, 2016
    Applicants: TOKYO UNIVERSITY OF SCIENCE FOUNDATION, DIC CORPORATION
    Inventors: Shunsuke Kobayashi, Kiyofumi Takeuchi, Masakazu Kaneoya
  • Publication number: 20160122644
    Abstract: The present invention provides a method of uniformizing output light from a liquid crystal display element and a liquid crystal display element in which output light is uniformized. The method of uniformizing output light of a liquid crystal display element includes: using a composition containing nanoparticles with an average particle diameter of 1 nm to 100 nm as a liquid crystal composition included in a liquid crystal layer in the liquid crystal display element having the liquid crystal layer interposed between a pair of substrates, and uniformizing light output from the liquid crystal display element. The present invention also provides a liquid crystal display element obtained by applying the method of uniformizing output light.
    Type: Application
    Filed: October 27, 2015
    Publication date: May 5, 2016
    Applicants: TOKYO UNIVERSITY OF SCIENCE FOUNDATION, DIC CORPORATION
    Inventors: Shunsuke Kobayashi, Yukihide Shiraishi, Naoki Toshima, Mitsuhiro Akimoto, Kenzo Takeishi, Haruyoshi Takatsu, Kunihiko Kotani
  • Publication number: 20160122292
    Abstract: It is a subject of the present invention to provide a base generator which has high solubility to general-purpose organic solvents, can dissolve directly into a base-reactive compound, such as an epoxy-based compound, further is provided with both performance of high heat resistance and low nucleophilicity, and generates a strong base, a base-reactive composition comprising the base generator and a base-reactive compound, as well as a method for generating a base, etc. The present invention relates to a compound represented by the general formula (A), a base generator comprising the compound, a base-reactive composition which comprises the base generator and a base-reactive compound, as well as a method for generating a base, etc.
    Type: Application
    Filed: June 25, 2014
    Publication date: May 5, 2016
    Applicant: TOKYO UNIVERSITY OF SCIENCE FOUNDATION
    Inventors: Nobuhiko SAKAI, Kosuke YANABA, Koji ARIMITSU
  • Patent number: 9327013
    Abstract: An activity enhancer for an anticancer agent includes, as an active ingredient, a D-form amino acid residue-containing FNIII14 polypeptide, the D-form amino acid residue-containing FNIII14 being a polypeptide FNIII14 represented by SEQ ID NO: 1 in which at least one of amino acid residues at positions 1 to 13 is a D-form amino acid residue. An anticancer composition includes the activity enhancer for an anticancer agent and an anticancer agent.
    Type: Grant
    Filed: March 9, 2012
    Date of Patent: May 3, 2016
    Assignees: TOKYO UNIVERSITY OF SCIENCE FOUNDATION, SAGA UNIVERSITY, NATIONAL UNIVERSITY CORPORATION KAGAWA UNIVERSITY
    Inventors: Fumio Fukai, Hiroaki Kodama, Takuya Matsunaga
  • Patent number: 9332651
    Abstract: The invention provides is a process for producing a structure (22) with a metal film, including the steps of preparing a mother die (10) in which a first metal film (16) is formed on the surface of a base (12) on which a concave and convex pattern (14) is formed, forming a second metal film (18) on the first metal film (16), adhering a support member (20) to the second metal film (18), and separating the second metal film (18) to which the concave and convex pattern has been transferred to the second metal film (18) together with the support member from the first metal film (16). Preferably, the first metal film (16) is a film containing Cr and Al, and the second metal film (18) is a film containing at least one metal selected from the group consisting of Au, Ag, Cu, Al, and Pt.
    Type: Grant
    Filed: February 9, 2009
    Date of Patent: May 3, 2016
    Assignee: TOKYO UNIVERSITY OF SCIENCE FOUNDATION
    Inventor: Jun Taniguchi
  • Publication number: 20160043681
    Abstract: A switched reluctance motor includes: a stator provided with a plurality of stator teeth as salient poles in a radial fashion with winding wire wound around each of the plurality of stator teeth; a rotor provided with a plurality of rotor teeth as salient poles in a radial fashion; a driving circuit configured to apply a current to the winding wire for each phase; and a control device configured to control the driving circuit, the control device being configured to perform: starting rising of a current to the winding wire of a stator tooth of a phase being a non-excitation target due to stop of energization to the winding wire; and allowing the current applied to the winding wire of the stator tooth of a phase being an excitation target to fall.
    Type: Application
    Filed: July 17, 2015
    Publication date: February 11, 2016
    Applicants: Toyota Jidosha Kabushiki Kaisha, Tokyo University of Science Foundation
    Inventors: Jun-ichi DEGUCHI, Kazuya ARAKAWA, Kensuke YOSHIZUE, Nobukazu HOSHI, Noboru NAKAYAMA, Takuya IGUCHI
  • Patent number: 9233017
    Abstract: A lower back assistance apparatus including: a back frame 14 mounted to the back of a user and capable of movement following a user tilting forward; shoulder straps 22 that are attached to a back mounting section and extend towards the user trunk forward side for supporting the trunk of a user from the forward side; thigh plates 18 for mounting to the front of lower limbs of the user; coupling frames 20 with one end coupled to the thigh plates 18 and the other end coupled to the back frame 14 by joint sections 16 so as to allow relative movement with respect to the back frame 14, and capable of maintaining a non-bent profile during the relative movement; and actuators 40 that in an actuated state prevent the back frame 14 from tilting in the user forward direction.
    Type: Grant
    Filed: March 4, 2010
    Date of Patent: January 12, 2016
    Assignee: TOKYO UNIVERSITY OF SCIENCE FOUNDATION
    Inventors: Hiroshi Kobayashi, Takuya Hashimoto, Yutaka Sato, Eiji Ishowata, Keita Suzuki, Hiroyuki Kobayashi, Kouhei Yamamoto
  • Publication number: 20160002364
    Abstract: A growth enhancer for Lactobacillus murinus, Lactobacillus salivarius, or a bacterium that belongs to the genus Lactobacillus and that has a homology of 16S rDNA of 90% or higher with Lactobacillus murinus or Lactobacillus salivarius includes a ?-glucan having a molecular weight of from 0.2 K to 50 K. A regulatory T-cell number increasing agent, a method of enhancing growth of a lactic acid bacterium, a method of increasing the number of regulatory T-cells, a method of evaluating a regulatory T-cell number increasing effect, and a method of evaluating a growth enhancing effect on a lactic acid bacterium are also provided.
    Type: Application
    Filed: March 10, 2014
    Publication date: January 7, 2016
    Applicant: TOKYO UNIVERSITY OF SCIENCE FOUNDATION
    Inventors: Yoichiro Iwakura, Ce Tang, Naohito Ohno
  • Publication number: 20150287993
    Abstract: It is an object of the present invention to provide an electrode capable of maintaining superior capacity retention without destruction of an electrode structure, even in the case of using an active material including silicon.
    Type: Application
    Filed: October 25, 2013
    Publication date: October 8, 2015
    Applicants: WAKO PURE CHEMICAL INDUSTRIES, LTD., Tokyo University of Science Foundation
    Inventors: Shinichi Komaba, Naoaki Yabuuchi, Zhen-Ji Han, Takeo Sasaki, Shota Hashimoto, Kuniaki Okamoto, Tsuneaki Maesawa