Patents Assigned to TOKYO UNIVERSITY OF SCIENCE FOUNDATION
  • Patent number: 10792300
    Abstract: A dendritic cell immune receptor activator, comprising a compound having a sugar chain as an active ingredient, the sugar chain having a basic structure represented by the following formula: wherein, in the formula, a sialic acid does not exist at two non-reducing terminals, and each of x and y independently represents 3 or 4.
    Type: Grant
    Filed: July 10, 2015
    Date of Patent: October 6, 2020
    Assignee: TOKYO UNIVERSITY OF SCIENCE FOUNDATION
    Inventors: Yoichiro Iwakura, Tomonori Kaifu, Rikio Yabe
  • Publication number: 20200299583
    Abstract: A fire retardant material comprising a carbon fiber which tensile elasticity is 700 GPa or more, and a fire retardant resin such as polycarbonate.
    Type: Application
    Filed: October 12, 2018
    Publication date: September 24, 2020
    Applicant: TOKYO UNIVERSITY OF SCIENCE FOUNDATION
    Inventors: Koichi YONEMOTO, Kiyoto MURAKAMI, Satoshi NONAKA
  • Publication number: 20200303086
    Abstract: A method for manufacturing an electroconductive pattern 40, provided with: a lamination step for laminating an acid generation film 10 containing an acid proliferation agent and a photoacid generator on a polymer film 20 containing an electroconductive polymer formed on a substrate 21; a masking step for masking the top of the acid generation film 10; a light irradiation step for irradiating the laminate from the acid-generation-film 10 side; a doping step for doping the electroconductive polymer with an acid generated and proliferated in the acid generation film 10 by the light irradiation; and a releasing step for releasing the acid generation film 10 from the polymer film 20. This method makes it possible to provide an electroconductive film and a method for manufacturing an electroconductive pattern in which photoacid generation and acid proliferation effects are utilized.
    Type: Application
    Filed: June 8, 2020
    Publication date: September 24, 2020
    Applicants: TOKYO UNIVERSITY OF SCIENCE FOUNDATION, NISSAN CHEMICAL INDUSTRIES, LTD.
    Inventors: Koji ARIMITSU, Makoto WAKABAYASHI
  • Patent number: 10781423
    Abstract: It is an object of the present invention to provide a method for easily producing an antigen-specific B cell population comprising IgG-positive B cells specific to a specific antigen. The present invention provides a method for producing a B cell population, comprising culturing B cells, in which the expression of a Bach2 gene has been increased, in the presence of a means for acting on CD40 and/or a BAFF receptor.
    Type: Grant
    Filed: November 5, 2018
    Date of Patent: September 22, 2020
    Assignees: TOKYO UNIVERSITY OF SCIENCE FOUNDATION, KANEKA CORPORATION
    Inventors: Daisuke Kitamura, Tomoyuki Nakaishi
  • Patent number: 10774062
    Abstract: An object of the present invention is to provide a photocuring method, which makes it possible to rapidly and efficiently obtain a crosslinked product (resin), a compound used in the photocuring method, and a photocuring resin composition containing the compound. The present invention relates to a photocuring method, which comprises a step 1 and a step 2 performed after the step 1, a compound used in the photocuring method, and a photocuring resin composition containing the compound. Step 1: this is a step in which in the presence of (A) compound having a carbonyl group generating a radical by photoirradiation and a carboxyl group decarboxylated by photoirradiation, (B) silane coupling agent having a mercapto group or a (meth)acryl group is reacted with (C) water under acidic conditions to obtain (D) silane compound having a mercapto group or a (meth)acryl group and at least one silanol group.
    Type: Grant
    Filed: January 25, 2017
    Date of Patent: September 15, 2020
    Assignees: FUJIFILM Wako Pure Chemical Corporation, TOKYO UNIVERSITY OF SCIENCE FOUNDATION
    Inventors: Nobuhiko Sakai, Kosuke Yanaba, Shigeaki Imazeki, Koji Arimitsu
  • Publication number: 20200261552
    Abstract: Provided are: a pharmaceutical composition for curing, treating, or preventing a disease involving a biological mechanism controlled by a dendritic cell immunoreceptor, in which the pharmaceutical composition contains a carbohydrate modifying enzyme as an active ingredient; and a method of curing, treating, or preventing a disease involving a biological mechanism controlled by a dendritic cell immunoreceptor.
    Type: Application
    Filed: May 14, 2018
    Publication date: August 20, 2020
    Applicant: Tokyo University of Science Foundation
    Inventors: Yoichiro IWAKURA, Tomonori KAIFU
  • Publication number: 20200255802
    Abstract: It is an object of the present invention to provide a method for easily producing an antigen-specific B cell population comprising IgG-positive B cells specific to a specific antigen. The present invention provides a method for producing a B cell population, comprising culturing B cells, in which the expression of a Bach2 gene has been increased, in the presence of a means for acting on CD40 and/or a BAFF receptor.
    Type: Application
    Filed: November 5, 2018
    Publication date: August 13, 2020
    Applicants: TOKYO UNIVERSITY OF SCIENCE FOUNDATION, KANEKA CORPORATION
    Inventors: Daisuke Kitamura, Tomoyuki Nakaishi
  • Patent number: 10722836
    Abstract: Provided is a hydrogen recovery method such that highly concentrated hydrogen gas can be obtained efficiently by adsorbing and removing hydrocarbon gas such as carbon dioxide, carbon monoxide, and methane, using a relatively low pressure, from pyrolysis gas obtained by heat treating biomass. The present invention is the method for recovering hydrogen from pyrolysis gas obtained by heat treating biomass, characterized by including: a first purifying step of adsorbing and removing gas that mainly includes carbon dioxide under pressure from the pyrolysis gas to purify the pyrolysis gas; and a second purifying step of further adsorbing and removing gas that includes carbon dioxide under pressure from purified gas obtained by the first purifying step at a pressure lower than the pressure in the first purifying step to purify the purified gas in order to recover hydrogen from the purified gas.
    Type: Grant
    Filed: October 28, 2015
    Date of Patent: July 28, 2020
    Assignees: Japan Blue Energy Co., Ltd., Tokyo University of Science Foundation
    Inventors: Naoki Dowaki, Mitsuo Kameyama, Kiyoshi Dowaki
  • Patent number: 10722480
    Abstract: An agent according to the present invention comprises as an effective component any of (1) disulfiram, diethyldithiocarbamate, or a metal complex of diethyldithiocarbamate; (2) a pharmaceutically acceptable salt of (1); or (3) a solvate of (1) or (2), and is used for inhibition of interaction between CR2B or CCR5 and FROUNT protein, inhibition of macrophages, control of cells constituting a cancer microenvironment or inflammatory microenvironment, or enhancement of anticancer activity of an anticancer drug. It is also possible to provide a compound with a reduced side effect and an increased pharmacological effect by identifying a disulfiram derivative having a lower aldehyde dehydrogenase-inhibiting activity and a higher FROUNT-inhibiting activity among derivatives prepared by structural modification of disulfiram.
    Type: Grant
    Filed: January 6, 2016
    Date of Patent: July 28, 2020
    Assignee: TOKYO UNIVERSITY OF SCIENCE FOUNDATION
    Inventors: Yuya Terashima, Kouji Matsushima, Etsuko Toda, Hiroaki Terasawa, Sosuke Yoshinaga
  • Patent number: 10720259
    Abstract: A method for manufacturing an electroconductive pattern 40, provided with: a lamination step for laminating an acid generation film 10 containing an acid proliferation agent and a photoacid generator on a polymer film 20 containing an electroconductive polymer formed on a substrate 21; a masking step for masking the top of the acid generation film 10; a light irradiation step for irradiating the laminate from the acid-generation-film 10 side; a doping step for doping the electroconductive polymer with an acid generated and proliferated in the acid generation film 10 by the light irradiation; and a releasing step for releasing the acid generation film 10 from the polymer film 20. This method makes it possible to provide an electroconductive film and a method for manufacturing an electroconductive pattern in which photoacid generation and acid proliferation effects are utilized.
    Type: Grant
    Filed: September 1, 2015
    Date of Patent: July 21, 2020
    Assignees: TOKYO UNIVERSITY OF SCIENCE FOUNDATION, NISSAN CHEMICAL INDUSTRIES, LTD.
    Inventors: Koji Arimitsu, Makoto Wakabayashi
  • Patent number: 10703911
    Abstract: Organic colorant represented by General Formula (1) below: where in the General Formula (1), R1 and R2 each independently represent C1-C20 alkyl group, C1-C20 alkenyl group, phenyl group, naphthyl group, or group represented by —(CH2)n—COO—R3, —(CH2)n—R4, —(CH2)n—CONH—R5, —CR6R7—COO—R8, or —(CH2)n—OCOCH3; R3 represents hydrogen atom or C1-C2 alkyl group; R4 represents hydroxy group, C1-C2 alkoxy group, C2-C5 alkenyloxy group, SO3Na group, OSO3Na group, phenyl group, phenylalkyl group, naphthyl group, or naphthylalkyl group; R5 represents C1-C20 alkyl group, C1-C20 alkenyl group, or C1-C12 hydroxyalkyl group; R6 represents hydrogen atom or methyl group; R7 represents C1-C4 alkyl group; R8 represents C1-C5 alkyl group; and n is integer of from 1 to 12.
    Type: Grant
    Filed: July 5, 2018
    Date of Patent: July 7, 2020
    Assignees: Ricoh Company, Ltd., Tokyo University of Science Foundation
    Inventors: Takuya Fujita, Yoshimasa Miyazawa, Tatsuya Tomura, Masahiro Yanagisawa, Kiyofumi Nagai, Yukishige Kondo, Juki Migii
  • Patent number: 10696703
    Abstract: Provided are: eushearilides; a method for producing eushearilides; a production intermediate; and a pharmaceutical composition containing eushearilides. By having the Wittig reaction process, Mukaiyama Aldol reaction process and Macrolactonizaion process serve as key processes, eushearilides represented by formula (I) are efficiently produced.
    Type: Grant
    Filed: October 28, 2015
    Date of Patent: June 30, 2020
    Assignee: TOKYO UNIVERSITY OF SCIENCE FOUNDATION
    Inventors: Isamu Shiina, Takayuki Tonoi
  • Publication number: 20200179901
    Abstract: The present invention provides a new hydrogen chloride removing agent that exhibits a good hydrogen chloride removal effect at a relatively low temperature. The present invention preferably provides a new hydrogen chloride removing agent for removing hydrogen chloride contained in a hydrogen-chloride-containing gas, such as a pyrolysis gas, a combustion exhaust gas, a dry distillation gas, etc., especially hydrogen chloride contained in a biomass pyrolysis gas. The present invention relates to a hydrogen chloride removing agent characterized by containing a mixture of a calcium carbonate and an imogolite and/or a synthetic imogolite, and relates to a method for removing, by using said hydrogen chloride removing agent, hydrogen chloride contained in a hydrogen-chloride-containing gas, especially hydrogen chloride contained in a biomass pyrolysis gas.
    Type: Application
    Filed: July 20, 2017
    Publication date: June 11, 2020
    Applicants: Japan Blue Energy Co., Ltd., Tokyo University of Science Foundation
    Inventors: Naoki Dowaki, Mitsuo Kameyama, Kiyoshi Dowaki
  • Patent number: 10655029
    Abstract: An inkjet ink including: a stilbene-based compound represented by General Formula (1) below; where in the General Formula (1), R1 and R3 each independently represent, for example, an alkyl group including 1 to 20 carbon atoms, an alkenyl group including 1 to 20 carbon atoms, a phenyl group, or a naphthyl group.
    Type: Grant
    Filed: October 3, 2017
    Date of Patent: May 19, 2020
    Assignees: Ricoh Company, Ltd., Tokyo University of Science Foundation
    Inventors: Takuya Fujita, Yoshimasa Miyazawa, Hisashi Habashi, Tatsuya Tomura, Tomohiro Inoue, Yukishige Kondo, Yutaka Takahashi
  • Publication number: 20200115282
    Abstract: Provided is a concrete composition, including: blast furnace slag; at least any one of expansive additive and cement; and water, wherein a unit water content of the water is 130 kg/m3 or less; wherein a content of the cement is 22% by mass or less relative to the blast furnace slag, and wherein a slump flow value of the concrete composition is 40 cm or greater.
    Type: Application
    Filed: April 11, 2018
    Publication date: April 16, 2020
    Applicants: SUMITOMO MITSUI CONSTRUCTION CO., LTD., The University of Tokyo, Tokyo University of Science Foundation
    Inventors: Taku Matsuda, Takafumi Noguchi, Manabu Kanematsu
  • Patent number: 10596265
    Abstract: A nanogel comprising a self-organizing peptide, a chitosan and polyethylene glycol is described.
    Type: Grant
    Filed: August 24, 2015
    Date of Patent: March 24, 2020
    Assignees: 3-D Matrix, Ltd., Tokyo University of Science Foundation
    Inventors: Hidenori Otsuka, Daisuke Matsukuma
  • Patent number: 10593992
    Abstract: Provided are: a potassium ion secondary battery which is not susceptible to deterioration of charge/discharge capacity even if charging and discharging are repeated, and which has a long service life as a secondary battery; a potassium ion capacitor; a negative electrode for the potassium ion secondary battery; and a negative electrode for the potassium ion capacitor. A negative electrode for potassium ion secondary batteries and a negative electrode for potassium ion capacitors, each of which contains a carbon material that is capable of absorbing and desorbing potassium and a binder that contains a polycarboxylic acid and/or a salt thereof. A potassium ion secondary battery which is provided with the negative electrode or the capacitor. A binder for negative electrodes of potassium ion secondary batteries or negative electrodes of potassium ion capacitors, which contains a polycarboxylic acid and/or a salt thereof.
    Type: Grant
    Filed: September 3, 2015
    Date of Patent: March 17, 2020
    Assignee: TOKYO UNIVERSITY OF SCIENCE FOUNDATION
    Inventors: Shinichi Komaba, Kei Kubota, Mouad Dahbi, Tatsuya Hasegawa
  • Publication number: 20200071410
    Abstract: It is an object of the present invention to provide a method for efficiently producing a B cell population comprising B cells that recognize a specific antigen. According to the present invention, provided is a method for producing a B cell population, comprising: a step (c) of culturing a cell population comprising B cells together with a specific antigen in the absence of IL-21, in the absence of IL-4, and in the presence of a cytokine other than IL-21 and IL-4, while giving stimulation mediated by CD40 and a BAFF receptor to the cells; and a step (d) of culturing the cell population comprising B cells, while giving stimulation mediated by has to the cells, so as to obtain a B cell population comprising B cells that recognize the specific antigen.
    Type: Application
    Filed: January 15, 2018
    Publication date: March 5, 2020
    Applicants: KANEKA CORPORATION, TOKYO UNIVERSITY OF SCIENCE FOUNDATION
    Inventors: Tatsuya Moutai, Tomoyuki Nakaishi, Hiroshi Kita, Mitsuaki Kitano, Daisuke Kitamura
  • Publication number: 20200000927
    Abstract: A Ras protein degradation inducing molecule that can induce degradation of Ras proteins, and a pharmaceutical composition that contains this Ras protein degradation inducing molecule are provided. The Ras protein degradation inducing molecule is a conjugate of a Ras protein affinity molecule which has affinity to Ras proteins, and a proteolysis-inducing tag which has affinity to protease and does not inhibit proteolysis of proteins by the protease.
    Type: Application
    Filed: November 13, 2017
    Publication date: January 2, 2020
    Applicant: Tokyo University of Science Foundation
    Inventors: Etsuko MIYAMOTO, Masaaki OZAWA
  • Publication number: 20200002163
    Abstract: A hydrogen storage cartridge small and lightweight allows storage and discharge of hydrogen at low pressure and normal temperature. It also can effectively absorb the volume expansion accompanying atomization of a hydrogen storage alloy that occurs due to repeated storage and discharge of hydrogen, and therefore a hydrogen storage cartridge (A) is provided in which deformation due to repeated use, and in particular irregular deformation, extremely unlikely, also it can effectively avoid hydrogen storage irregularities of the hydrogen storage alloy. The hydrogen storage cartridge (A) is used for storage of hydrogen contained in biomass thermal decomposition gas, wherein the material of the hydrogen storage cartridge (A) is pure titanium, and the hydrogen storage cartridge (A) includes in the interior space (1), as a hydrogen storage alloy, at least one hydrogen storage alloy selected from the group comprising lanthanum mischmetal/nickel, titanium/iron, calcium/nickel, and lanthanum/nickel.
    Type: Application
    Filed: January 31, 2017
    Publication date: January 2, 2020
    Applicants: Japan Blue Energy Co., Ltd., Tokyo University of Science Foundation, Nomura International Co., Ltd.
    Inventors: Naoki Dowaki, Mitsuo Kameyama, Kiyoshi Dowaki, Noboru Katayama