Abstract: A head-mounted device includes: an outer shell; a first flow channel that is a gap between a head of a wearer and the outer shell; a second flow channel provided in the outer shell and joining the first flow channel; a fan configured to blow air from one of the first flow channel and the second flow channel to the other of the first flow channel and the second flow channel; a first humidity sensor configured to measure an absolute humidity of intake air entering one of the first flow channel and the second flow channel; and a second humidity sensor configured to measure an absolute humidity of exhaust air exiting from the other of the first flow channel and the second flow channel.
Type:
Grant
Filed:
October 18, 2018
Date of Patent:
September 21, 2021
Assignees:
TOKYO UNIVERSITY OF SCIENCE FOUNDATION, FUJITA CORPORATION
Abstract: Polycrystalline magnesium silicide containing only carbon as a dopant and having carbon distributed at the crystal grain boundaries and within the crystal grains, a thermoelectric conversion material obtained using the polycrystalline magnesium silicide, a sintered compact, a thermoelectric conversion element, and a thermoelectric conversion module, and methods for producing polycrystalline magnesium silicide and a sintered compact.
Abstract: A three-dimensional printing system (1) includes: a head (2) to which a first continuous material (FL) including a resin and a second continuous material (FB) including fibers are fed; a platform (3) on which a printing material based on the first and second continuous materials from the head is stacked; a cutting device (10) which is capable of cutting at least fibers; and a controller (5) which controls an operation device including at least one of the head, the platform, and the cutting device.
Type:
Grant
Filed:
May 27, 2015
Date of Patent:
August 31, 2021
Assignees:
Nihon University, Tokyo University of Science Foundation
Abstract: An energy-sensitive composition including at least one of a silane compound monomer capable of forming a polysilane compound, a silane compound oligomer and the polysilane compound, and a base generator (B) represented by the following formula (1): in which R1 to R11 each independently represents a hydrogen atom, a halogen atom, a nitro group, an alkyl group, an aryl group, an arylalkyl group or an alkoxy group, R5 and R6 may be connected to each other via a single bond or a divalent linking group, Zq+ represents a q-valent counter cation composed of a base having a pKa of 24 or more, and q represents an integer of 1 or more.
Type:
Grant
Filed:
April 22, 2019
Date of Patent:
August 31, 2021
Assignees:
Tokyo Ohka Kogyo Co., Ltd., Tokyo University of Science Foundation
Inventors:
Kunihiro Noda, Dai Shiota, Koji Arimitsu
Abstract: To provide a moth-eye transfer mold and a method of manufacturing a moth-eye transfer mold that provide a simple and inexpensive manufacturing process. A moth-eye transfer mold 1 is characterized by including a base 10, an underlayer 20 formed on the base 10, and a glassy carbon layer 30 formed on the underlayer 20, the glassy carbon layer 30 has an inverted moth-eye structure RM over a surface 30a, and the inverted moth-eye structure RM is randomly arranged cone-shaped pores.
Type:
Grant
Filed:
June 12, 2019
Date of Patent:
August 17, 2021
Assignees:
Tokyo University of Science Foundation, GEOMATEC CO., LTD.
Abstract: A Ras protein degradation inducing molecule that can induce degradation of Ras proteins, and a pharmaceutical composition that contains this Ras protein degradation inducing molecule are provided. The Ras protein degradation inducing molecule is a conjugate of a Ras protein affinity molecule which has affinity to Ras proteins, and a proteolysis-inducing tag which has affinity to protease and does not inhibit proteolysis of proteins by the protease.
Abstract: Provided are an anticancer agent, radiosensitizer, and food composition capable of enhancing the effects of radiation therapy. The present inventors discovered that tumors shrink significantly in comparison to an untreated group and the respective monotherapy groups when treatment by burdock fruit extract containing arctigenin and radiation therapy were used in combination on mice transplanted with human pancreatic cancer cells. The anticancer agent of the present invention is an anticancer agent containing arctigenin and/or arctiin as the active ingredient, to be used in combination with radiation therapy. The arctigenin and/or arctiin may be contained as burdock, burdock fruit, burdock sprout, or forsythia, or an extract extracted from these.
Type:
Application
Filed:
July 10, 2017
Publication date:
June 10, 2021
Applicants:
KRACIE PHARMA, LTD., NATIONAL CANCER CENTER, TOKYO UNIVERSITY OF SCIENCE FOUNDATION
Abstract: A p53 degradation inducing molecule which can induce degradation of p53 proteins or p53 composites, and a pharmaceutical composition containing said p53 degradation inducing molecule are provided. This p53 degradation inducing molecule is a conjugate of a p53 affinity molecule which has affinity for p53 proteins or p53 composites, and a proteolysis induction tag which has affinity for protease and which does not inhibit proteolysis of proteins by protease.
Abstract: Provided are: a protein degradation inducing tag which is a molecule that has affinity with proteases and does not inhibit degradation of a protein by proteases; a protein degradation inducing molecule that is a conjugate of at least one protein degradation inducing tag and at least one protein binding molecule that binds to a protein; and a usage of those.
Abstract: Provided are: a protein degradation inducing tag which is a molecule that has affinity with proteases and does not inhibit degradation of a protein by proteases; a protein degradation inducing molecule that is a conjugate of at least one protein degradation inducing tag and at least one protein binding molecule that binds to a protein; and a usage of those.
Abstract: An active energy ray-curable composition is disclosed including: an anionically polymerizable compound represented by (1): wherein EWG represents an electron-withdrawing group, X represents a single bond or an oxygen atom (—O—), R represents an n-valent organic group, and n represents an integer of 1 to 6; when n is an integer of 2 to 6, the respective EWG and the respective X may be the same or different; and when n is 1, EWG and R may be bonded; and a compound (photobase generator) represented by (2): wherein ring A represents an aromatic ring that may be substituted or a heteroaromatic ring that may be substituted; R1 and R2 are the same or different and each represents a hydrogen atom or an alkyl group; R1 and R2 may be bonded to each other to form a ring together with an adjacent nitrogen atom; and the ring may be substituted.
Type:
Application
Filed:
November 30, 2018
Publication date:
March 11, 2021
Applicants:
TOKYO UNIVERSITY OF SCIENCE FOUNDATION, TOAGOSEI CO., LTD.
Abstract: An object of the present invention is to find a ligand for a DCIR and to search for an agonist and an antagonist for the DCIR. Specifically, disclosed are: a dendritic cell immunoreceptor agonist containing keratan sulfate-II (KS-II) as an active ingredient; an antibody against dendritic cell immunoreceptor, having a keratan sulfate-II-like dendritic cell immunoreceptor agonism; and an antibody against a dendritic cell immunoreceptor, having a keratan sulfate-II inhibitory dendritic cell immunoreceptor antagonism.
Type:
Application
Filed:
August 12, 2020
Publication date:
February 11, 2021
Applicant:
TOKYO UNIVERSITY OF SCIENCE FOUNDATION
Inventors:
Yoichiro IWAKURA, Noriyuki Fujikado, Guangyu Ma
Abstract: In a control device for a switched reluctance motor, a voltage drop control is executed in which a voltage dropped to be lower than a voltage applied in a case where the switched reluctance motor is driven in a high-load region is applied to the switched reluctance motor, in a case where the switched reluctance motor is driven in a low-load region. The low-load region is a lower load region than the high-load region.
Type:
Grant
Filed:
October 2, 2017
Date of Patent:
February 2, 2021
Assignees:
TOYOTA JIDOSHA KABUSHIKI KAISHA, Tokyo University of Science Foundation
Abstract: An object of the present disclosure is to provide a fuel cell separator having a low contact resistance due to a tin oxide film and having an excellent corrosion resistance. An embodiment is a method for manufacturing a fuel cell separator including a stainless steel substrate. The method includes forming the tin oxide film on a surface of the stainless steel substrate; and attaching phosphoric acid or phosphate to at least a defective portion in the tin oxide film.
Type:
Grant
Filed:
June 18, 2019
Date of Patent:
January 19, 2021
Assignees:
TOYOTA JIDOSHA KABUSHIKI KAISHA, TOKYO UNIVERSITY OF SCIENCE FOUNDATION
Abstract: Disclosed are a novel therapeutic means effective and practical against cancer, and a novel substance useful as such a therapeutic means. Provided are novel peptides derived from a partial region of HMGN1, HMGN2, HMGN4 or HMGN5, and anti-cancer agents and anti-cancer effect enhancers containing the peptide as an active ingredient. The peptide of the present invention has an anti-tumor effect even independently, and exerts a remarkably excellent anti-tumor effect particularly when used in combination with an immune checkpoint regulator, or an anti-CD4 antibody or antigen-binding fragment thereof.
Type:
Application
Filed:
March 7, 2019
Publication date:
December 31, 2020
Applicants:
The University of Tokyo, ONO PHARMACEUTICAL CO., LTD., TOKYO UNIVERSITY OF SCIENCE FOUNDATION
Abstract: It is an object of the present invention to provide an electrode capable of maintaining superior capacity retention without destruction of an electrode structure, even in the case of using an active material including silicon.
Type:
Grant
Filed:
November 21, 2017
Date of Patent:
December 8, 2020
Assignees:
TOKYO UNIVERSITY OF SCIENCE FOUNDATION, FUJIFILM WAKO PURE CHEMICAL CORPORATION
Abstract: It is an object of the present invention to provide an electrode having superior charge-discharge capacity, even in the case of using an active material containing silicon.
Type:
Grant
Filed:
April 21, 2015
Date of Patent:
December 1, 2020
Assignees:
TOKYO UNIVERSITY OF SCIENCE FOUNDATION, FUJIFILM WAKO PURE CHEMICAL CORPORATION
Abstract: Provided are a boron-doped nanodiamond having a large specific surface area and high electrical conductivity, an electrode containing the boron-doped nanodiamond, and a sensor or an electricity storage device provided with the electrode. The boron-doped nanodiamond of the present invention has a specific surface area of 110 m2/g or greater and electrical conductivity at 20° C. of 5.0×10?3 S/cm or greater. The boron-doped nanodiamond preferably has a median diameter of 200 nm or smaller. Additionally, the electrode of the present invention contains the boron-doped nanodiamond.
Type:
Application
Filed:
August 28, 2018
Publication date:
November 12, 2020
Applicants:
DAICEL CORPORATION, TOKYO UNIVERSITY OF SCIENCE FOUNDATION
Abstract: Provided is a concrete composition, including: blast furnace slag; at least any one of expansive additive and cement; and water, wherein a unit water content of the water is 130 kg/m3 or less; wherein a content of the cement is 22% by mass or less relative to the blast furnace slag, and wherein a slump flow value of the concrete composition is 40 cm or greater.
Type:
Grant
Filed:
April 11, 2018
Date of Patent:
October 20, 2020
Assignees:
SUMITOMO MITSUI CONSTRUCTION CO., LTD., THE UNIVERSITY OF TOKYO, TOKYO UNIVERSITY OF SCIENCE FOUNDATION