Abstract: An ink includes a boron-doped nanodiamond having a specific surface area of 110 m2/g or greater, and electrical conductivity at 20° C. of 5.0×10?3 S/cm or greater.

Abstract: The aim is to provide a novel compound that can luminesce with high brightness and be used as a luminescent substrate in a firefly bioluminescence system. Provided is a heterocyclic compound, or salt thereof, represented by the following general formula (1): [R1, R2, and R3 are independently hydrogen or an alkyl group having a carbon number of 1-4, with provisos that R1 and R2 are optionally bonded to form a ring and that one of R1 and R2 is optionally bonded to Y1 to form a ring; X is S, O, NR4, or CH2, and Y1 and Y2 are independently N or CR4, where each R4 is independently hydrogen, an alkyl group having a carbon number of 1-4, an alkenyl group having a carbon number of 2-4, or an acyl group having a carbon number of 2-4; n is an integer of 0-4].

Abstract: A thermal radiation lens is configured to control propagation of thermal radiation, by using a sheet-type material 10 which realizes high refractive-index, non-reflective, and non-polarizing optical properties for a frequency band of a thermal radiation region. The sheet-type material 10 according to the present embodiment includes a substrate 11, a first pattern array 12 arranged regularly in the X-axis direction and the Y-axis direction on one surface of the substrate 11, and a second pattern array 13 formed on the back surface of the substrate relative to the one surface to overlap with the first pattern array, wherein meta-atoms 12a, 13a included in first and second pattern arrays have the same shape and have a width in the X-axis direction and a width in the Y-axis direction which are equivalent to each other within a range of a half wavelength of the thermal radiation.

Abstract: A problem of this invention it to provide a method for differentiate a primordial germ cell into a functional GV stage oocyte by in vitro culture. This invention relates to a method for differentiating a primordial germ cell into a functional GV stage oocyte by in vitro culture, comprising: (a) a step of producing a secondary follicle by culturing the primordial germ cell and supporting cells adjacent to the primordial germ cells under conditions that eliminate the effects of estrogen or a factor having a similar function to estrogen; (b) a step of partially dissociating cells between a granulosa cell layer and a thecal cell layer, wherein an oocyte, the granulosa cell layer, and the thecal cell layer constitute the produced secondary follicle; and (c) a step of differentiating the oocyte into a functional GV stage oocyte by culturing the oocyte, the granulosa cell layer, and the thecal cell layer that constitute the secondary follicle in a medium containing a high-molecular-weight compound.

Abstract: The sensor of a fluid sensor system includes an outer peripheral sensor unit including three or more sensor pairs to surround and sandwich the heating element. The computing device of the system includes a first identification unit identifies a sensor pair in which an output difference between an output value corresponding to a temperature detected by one temperature sensor of the sensor pair and an output value corresponding to a temperature detected by the other temperature sensor of the sensor pair is largest, a second identification unit identifies other sensor pairs adjacent to the identified sensor pair in the circumferential direction, and a flow direction estimation unit estimates the flow direction of the fluid on the basis of the output difference in the sensor pair having the largest output difference and output differences in the other sensor pairs adjacent to the sensor pair in the circumferential direction.

Abstract: Provided is an electrode-forming material for an electrochemical capacitor useful for forming an electrode of an electrochemical capacitor having a high storage capacity and a high energy density. The electrode-forming material for an electrochemical capacitor according to an embodiment of the present invention includes boron-doped nanodiamond (A) having a specific surface area of 110 m2/g or greater and an electrical conductivity at 20° C. of 5.0×10?3 S/cm or greater; and a metal oxide (B), and the content of the (B) is from 20 to 95 mass % with respect to the total content of the (A) and (B).

Abstract: Provided is a head-mounted display that enables viewing of a stereoscopic image without visual fatigue caused by vergence-accommodation conflict. A head-mounted display includes a display device to display images for the left eye and the right eye on a screen, virtual image forming optical systems for the left eye and the right eye, respectively disposed with respect to images for the left eye and the right eye on the screen, and wide-focus lenses for the left eye and the right eye having a negative focal length with a range, and respectively disposed with respect to the virtual image forming optical systems for the left eye and the right eye so as to overlap optical axis directions of the virtual image forming optical systems for the left eye and the right eye. By respectively displaying virtual images of images, a permissible range of vergence and accommodation is expanded.

Abstract: A compound represented by Chemical formula 1: wherein n is an integer of 2 or more, is provided. Also provided is a derivatization reagent for derivatizing a diene-containing compound, including a compound represented by Chemical formula 1. Further provided is a synthesis method for a compound, including a nucleophilic substitution reaction between an aryl halide and a heterocyclic amine compound being saturated, the compound being represented by Chemical formula 1.

Abstract: Disclosed are a novel therapeutic means effective and practical against cancer, and a novel substance useful as such a therapeutic means. Provided are novel peptides derived from a partial region of HMGN1, HMGN2, HMGN4 or HMGN5, and anti-cancer agents and anti-cancer effect enhancers containing the peptide as an active ingredient. The peptide of the present invention has an anti-tumor effect even independently, and exerts a remarkably excellent anti-tumor effect particularly when used in combination with an immune checkpoint regulator, or an anti-CD4 antibody or antigen-binding fragment thereof.

Abstract: The aim is to provide a novel compound that can luminesce with high brightness and be used as a luminescent substrate in a firefly bioluminescence system. Provided is a heterocyclic compound, or salt thereof, represented by the following general formula (1): [R1, R2, and R3 are independently hydrogen or an alkyl group having a carbon number of 1-4, with provisos that R1 and R2 are optionally bonded to form a ring and that one of R1 and R2 is optionally bonded to Y1 to form a ring; X is S, O, NR4, or CH2, and Y1 and Y2 are independently N or CR4, where each R4 is independently hydrogen, an alkyl group having a carbon number of 1-4, an alkenyl group having a carbon number of 2-4, or an acyl group having a carbon number of 2-4; n is an integer of 0-4].

Abstract: [Problem] To develop a group of novel compounds with an inhibitory activity against the function of Pin1 so as to use them as candidate compounds for medicaments.

Abstract: A compound represented by the general formula (I) given below or a pharmacologically acceptable salt thereof has been found to have a strong G9a inhibitory effect. The compound (I) or the pharmacologically acceptable salt thereof inhibits G9a and thereby has high usefulness for the treatment, prevention or suppression of various pathological conditions (proliferative disease such as cancer, ?-globin abnormality, fibrosis, pain, neurodegenerative disease, Prader-Willi syndrome, malaria, viral infection, myopathy, autism, etc.).

Abstract: The purpose of the present invention is to provide a thermoelectric conversion element having a film which not only maintains sufficient adhesion even when exposed to a high temperature but also exhibits excellent oxidation resistance and crack resistance. The problem is solved by a thermoelectric conversion element including a thermoelectric conversion component, in which the thermoelectric conversion component contains magnesium silicide and/or manganese silicide and is covered with a film containing Si and Zr.

Abstract: The present invention provides a binder for positive electrode of lithium ion battery which is excellent in workability at the time of producing a positive electrode, is excellent in charge and discharge characteristics such as cycle characteristics and rate characteristics, and enables to possible to produce a positive electrode having an extended cycle life, as well as the present invention provides a slurry for forming positive electrode mixture layer of lithium ion battery, a positive electrode for lithium ion battery, and a lithium ion battery, using the same.

Abstract: A sign detection device is provided with a plurality of sensors, a data acquisition unit, a calculation unit, and a detection unit. The plurality of sensors are respectively disposed at a plurality of positions of a detection target to measure a physical parameter at each positions. The data acquisition unit is configured to acquire time-series change data of the physical parameters from the plurality of sensors. The calculation unit is configured to calculate dynamic network information representing a time change of a complex network structure including a parameter indicating a correlation between the physical parameters at any two positions of the plurality of positions, on the basis of the time-series change data. The detection unit is configured to detect a sign of sudden change vibration of the detection target, on the basis of the dynamic network information.

Abstract: An estimation device includes a controller that: obtains first-type temperature data for a position corresponding to an outside of a first-type position of a pipe in which a fluid flows; obtains second-type temperature data for a position corresponding to an outside of a second-type position of the pipe at which condition related to heat transfer is different than condition at the first-type position; based on the first-type temperature data and the second-type temperature data, calculates thermal resistance of a deposit formed on an inner surface of the pipe, and estimates a thickness of the deposit.

Abstract: There is provided a light detecting device including: a laser light source generating light source pulse beam; a splitting section splitting the light source pulse beam into excitation beam, first probe beam and second probe beam; a first modulating section executing optical path length modulation that modulates a relative optical path length difference between the excitation beam, and the first probe beam and the second probe beam; a second modulating section phase-modulating the first probe beam; and a detecting section illuminating combined beam, in which the excitation beam, the first probe beam and the second probe beam are multiplexed, onto a sample, and detecting a stimulated Raman scattering signal that is generated.

Abstract: It is an object of the present invention to provide a method for efficiently producing a B cell population comprising B cells that recognize a specific antigen. According to the present invention, provided is a method for producing a B cell population, comprising: a step (c) of culturing a cell population comprising B cells together with a specific antigen in the absence of IL-21, in the absence of IL-4, and in the presence of a cytokine other than IL-21 and IL-4, while giving stimulation mediated by CD40 and a BAFF receptor to the cells; and a step (d) of culturing the cell population comprising B cells, while giving stimulation mediated by has to the cells, so as to obtain a B cell population comprising B cells that recognize the specific antigen.

Abstract: A driving assistance control device includes an active pedal configured to control a driving and braking force of a vehicle, an electronic control unit configured to detect a potential risk area in which an obstacle entering a scheduled traveling route of the vehicle is likely to be present, and determine a reference speed at which contact between the vehicle and the obstacle can be avoided even when the obstacle enters the scheduled traveling route of the vehicle from the detected potential risk area based on a positional relationship between the vehicle and the potential risk area, and a force feedback unit configured to apply an assistance reaction force in a direction in which the amount of manipulation is reduced, to the active pedal when a current speed of the vehicle exceeds the reference speed.

Abstract: Disclosed are a novel therapeutic means effective and practical against cancer, and a novel substance useful as such a therapeutic means. Provided are novel peptides derived from a partial region of HMGN1, HMGN2, HMGN4 or HMGN5, and anti-cancer agents and anti-cancer effect enhancers containing the peptide as an active ingredient. The peptide of the present invention has an anti-tumor effect even independently, and exerts a remarkably excellent anti-tumor effect particularly when used in combination with an immune checkpoint regulator, or an anti-CD4 antibody or antigen-binding fragment thereof.