Abstract: There is provided technology for promoting permeation of a substance into a cell layer. Provided is a cell layer permeation promoter comprising a compound represented by general formula (1). Also provided is a composition for facilitating drug absorption that contains the cell layer permeation promoter, said composition being for facilitating absorption of a drug into a living body. Also provided is a pharmaceutical composition that contains the cell layer permeation promoter and furthermore contains a drug to be absorbed into a living body.
Type:
Application
Filed:
March 19, 2020
Publication date:
July 21, 2022
Applicants:
University of Tsukuba, Tokyo University of Pharmacy and Life Sciences
Abstract: A method for producing a GaN crystal that includes: (i) a seed crystal preparation step of preparing a GaN seed crystal having one or more facets selected from a {10-10} facet and a {10-1-1} facet; and (ii) a growth step of growing GaN from vapor phase on a surface comprising the one or more facets of the GaN seed crystal using GaCl3 and NH3 as raw materials.
Type:
Grant
Filed:
February 18, 2021
Date of Patent:
June 28, 2022
Assignees:
MITSUBISHI CHEMICAL CORPORATION, NATIONAL UNIVERSITY CORPORATION TOKYO UNIVERSITY OF AGRICULTURE AND TECHNOLOGY
Abstract: This is to provide a composition for delivering a nucleic acid and a nucleic acid-containing composition which ensure stability of a nucleic acid drug, have a high intracellular introduction rate, can efficiently express the function of a nucleic acid drug, and have low cytotoxicity. Disclosed is a composition for delivering a nucleic acid and a nucleic acid-containing composition each comprises a block copolymer in which a polyethylene glycol segment and a hydrophobic polyester segment are linked, and a peptide having 4 to 30 residues containing at least one selected from the group consisting of arginine and lysine.
Type:
Grant
Filed:
July 11, 2018
Date of Patent:
May 31, 2022
Assignee:
TOKYO UNIVERSITY OF PHARMACY AND LIFE SCIENCES
Abstract: Provided is an electrode-forming material for an electrochemical capacitor useful for forming an electrode of an electrochemical capacitor having a high storage capacity and a high energy density. The electrode-forming material for an electrochemical capacitor according to an embodiment of the present invention includes boron-doped nanodiamond (A) having a specific surface area of 110 m2/g or greater and an electrical conductivity at 20° C. of 5.0×10?3 S/cm or greater; and a metal oxide (B), and the content of the (B) is from 20 to 95 mass % with respect to the total content of the (A) and (B).
Type:
Application
Filed:
February 28, 2020
Publication date:
May 19, 2022
Applicants:
DAICEL CORPORATION, TOKYO UNIVERSITY OF SCIENCE FOUNDATION
Abstract: Provided are: a pharmaceutical composition for curing, treating, or preventing a disease involving a biological mechanism controlled by a dendritic cell immunoreceptor, in which the pharmaceutical composition contains a carbohydrate modifying enzyme as an active ingredient; and a method of curing, treating, or preventing a disease involving a biological mechanism controlled by a dendritic cell immunoreceptor.
Abstract: The present invention provides a new hydrogen chloride removing agent that exhibits a good hydrogen chloride removal effect at a relatively low temperature. The present invention preferably provides a new hydrogen chloride removing agent for removing hydrogen chloride contained in a hydrogen-chloride-containing gas, such as a pyrolysis gas, a combustion exhaust gas, a dry distillation gas, etc., especially hydrogen chloride contained in a biomass pyrolysis gas. The present invention relates to a hydrogen chloride removing agent characterized by containing a mixture of a calcium carbonate and an imogolite and/or a synthetic imogolite, and relates to a method for removing, by using said hydrogen chloride removing agent, hydrogen chloride contained in a hydrogen-chloride-containing gas, especially hydrogen chloride contained in a biomass pyrolysis gas.
Type:
Grant
Filed:
July 20, 2017
Date of Patent:
May 3, 2022
Assignees:
JAPAN BLUE ENERGY CO., LTD., TOKYO UNIVERSITY OF SCIENCE FOUNDATION
Abstract: A map information provision system includes: a road map information database configured to store road map information; a vehicle position determination unit configured to detect and determine a position of a vehicle on a road; a road map information extraction unit configured to extract the road map information around the vehicle from the road map information database, based on the position of the vehicle; and a waypoint map constructor unit configured to determine positions of waypoints and configure a waypoint map that is made up of the plurality of the waypoints, wherein the waypoint map is supplied to a driving support device for the vehicle or a driving control device for the vehicle and is utilized as map information on the planned driving route.
Type:
Grant
Filed:
October 5, 2018
Date of Patent:
April 19, 2022
Assignees:
TOYOTA JIDOSHA KABUSHIKI KAISHA, THE UNIVERSITY OF TOKYO, National University Corporation Tokyo University of Agriculture and Technology, SCHOOL JUDICIAL PERSON IKUTOKU GAKUEN
Abstract: Provided are stereoscopic eyeglasses capable of reducing visual fatigue in binocular stereoscopic display by a simple configuration. In stereoscopic eyeglasses, in order to expand a tolerance of match between vergence and accommodation enabling comfortable stereovision in eyeglasses-using stereoscopic display, wide-focus lenses ranging in focal length are incorporated so as to overlap optical filters in light transmission directions, and accordingly, visual fatigue to be caused by vergence-accommodation conflict during stereoscopic image observation is reduced.
Type:
Grant
Filed:
June 7, 2019
Date of Patent:
April 12, 2022
Assignees:
National University Corporation Tokyo University of Agriculture and Technology, Itoh Optical Industrial Co., Ltd.
Abstract: A method for recovering hydrogen which is capable of efficiently recovering high concentration hydrogen gas by adsorbing and removing hydrocarbon gas such as carbon dioxide from biomass pyrolysis gas under a relatively low pressure, and also capable of storing the recovered high concentration hydrogen gas, preferably, in a cartridge type container that can be used as is as a hydrogen storing container for an apparatus equipped with a fuel cell. The method includes a first purifying stare of purifying biomass pyrolysis gas and a second purifying stage of purifying the obtained purified gas under a pressure equal to or less than the pressure in the first purifying stage to recover gas that contains hydrogen, and further includes a hydrogen storing stage of feeding the gas containing hydrogen recovered in the second purifying stage into the container filled with a hydrogen storage alloy and storing high purity hydrogen.
Type:
Grant
Filed:
August 23, 2016
Date of Patent:
March 15, 2022
Assignees:
JAPAN BLUE ENERGY CO., LTD., TOKYO UNIVERSITY OF SCIENCE FOUNDATION
Abstract: An ink includes a boron-doped nanodiamond having a specific surface area of 110 m2/g or greater, and electrical conductivity at 20° C. of 5.0×10?3 S/cm or greater.
Type:
Application
Filed:
November 18, 2021
Publication date:
March 10, 2022
Applicants:
DAICEL CORPORATION, TOKYO UNIVERSITY OF SCIENCE FOUNDATION
Abstract: A method of producing a shaped product for a thermoelectric conversion element is provided. The method comprises: mixing a coarse mixture that contains metal nanoparticle-supporting carbon nanotubes, a resin component, and a solvent by dispersion treatment that brings about a cavitation effect or a crushing effect, to obtain a composition for a thermoelectric conversion element; and removing the solvent from the composition for a thermoelectric conversion element.
Type:
Application
Filed:
October 26, 2021
Publication date:
February 10, 2022
Applicants:
ZEON CORPORATION, PUBLIC UNIVERSITY CORPORATION TOKYO UNIVERSITY OF SCIENCE, SANYO ONODA YAMAGUO
Abstract: The transplant fish production method includes selecting a donor fish species, selecting first and second fish species which are a combination that could be sterile, producing a hybrid fish species of the selected first fish species and second fish species, and transplanting reproductive cells of the donor fish species into the produced hybrid fish species.
Type:
Application
Filed:
March 1, 2021
Publication date:
January 27, 2022
Applicants:
National University Corporation Tokyo University of Marine Science and Technology, Nippon Suisan Kaisha, Ltd.
Abstract: An electrolyte solution for a potassium ion battery or a potassium ion capacitor, the electrolyte solution comprising at least one potassium salt compound selected from the group consisting of potassium bis(trifluoromethanesulfonyl)amide and potassium bis(fluorosulfonyl)amide and at least one solvent selected from the group consisting of ethylene glycol dimethyl ether, diethylene glycol dimethyl ether, triethylene glycol dimethyl ether, tetraethylene glycol dimethyl ether, pentaethylene glycol dimethyl ether, ethylene carbonate, and propylene carbonate, in which a concentration of the potassium salt compound in the electrolyte solution is from 1.5 mol/kg to 12.0 mol/kg.
Abstract: As one embodiment, the present invention provides a method for growing a ?-Ga2O3-based single crystal film by using HYPE method. The method includes a step of exposing a Ga2O3-based substrate to a gallium chloride-based gas and an oxygen-including gas, and growing a ?-Ga2O3-based single crystal film on a principal surface of the Ga2O3-based substrate at a growth temperature of not lower than 900° C.
Type:
Application
Filed:
September 10, 2021
Publication date:
December 30, 2021
Applicants:
TAMURA CORPORATION, NATIONAL UNIVERSITY CORPORATION TOKYO UNIVERSITY OF AGRICULTURE AND TECHNOLOGY
Abstract: A method of producing a molded product, the method including: pressing a mold having a surface including at least one of a concave part or a convex part against a photocurable positive electron beam resist; obtaining a molded product of the positive electron beam resist having a surface including a concave part and a convex part by irradiating the photocurable positive electron beam resist pressed against the resist with light to cure the resist; and partially decomposing the molded product of the positive electron beam resist in a region subjected to irradiation with an electron beam by irradiating the surface of the molded product of the positive electron beam resist with the electron beam.
Type:
Application
Filed:
July 26, 2019
Publication date:
December 23, 2021
Applicants:
TOKYO UNIVERSITY OF SCIENCE FOUNDATION, TOYO GOSEI CO., LTD.
Inventors:
Jun TANIGUCHI, Takao OKABE, Takeshi OSAKI, Takashi MIYAZAWA
Abstract: An object of the present invention is to develop a therapeutic agent for an inflammatory disease such as an inflammatory bowel disease or NASH, which therapeutic agent shows less side effects and high effectiveness. The present invention provides a compound represented by Formula (I) or a salt thereof; and a Pin1 inhibitor, a pharmaceutical composition, a therapeutic agent or a prophylactic agent for an inflammatory disease, and a therapeutic agent or a prophylactic agent for colon cancer, containing the compound.
Type:
Grant
Filed:
November 29, 2017
Date of Patent:
December 21, 2021
Assignees:
Hiroshima University, Tokyo University of Pharmacy & Life Sciences, The University of Tokyo
Abstract: A driving assistance system includes a driving readiness degree estimation unit configured to estimate a driving readiness degree relating to a driving consciousness of the driver based on the travel state of the vehicle or the driving operation of the vehicle by the driver and the traveling environment of the vehicle, a proportional gain calculation unit configured to calculate a proportional gain based on the driving readiness degree and the speed of the vehicle, and an assistance torque calculation unit configured to calculate the assistance torque according to a value obtained by multiplying a difference between the target steering angle and the actual steering angle by the proportional gain. If the speed is constant, the proportional gain calculation unit is configured to calculate the proportional gain as a smaller value as the driving readiness degree becomes lower.
Type:
Grant
Filed:
June 17, 2019
Date of Patent:
December 7, 2021
Assignees:
TOYOTA JIDOSHA KABUSHIKI KAISHA, National University Corporation Tokyo University of Agriculture and Technology
Abstract: Provided is a method for quantifying vitamin D, with the vitamin D contained in a biological sample being derivatized with a derivatization reagent and being measured with a mass spectrometer, the method including, a derivatization step of derivatizing n number of samples by using n types of 4-(4?-dimethylaminophenyl)-1,2,4-triazoline-3,5-dione (DAPTAD) isotopologues respectively as derivatization reagents, a mixing step of mixing the n types of derivatization samples obtained in the derivatization step, and a quantitative analysis step of subjecting each of the n types of vitamin D derivatives contained in the mixed sample obtained in the mixing step to quantitative analysis using a mass spectrometer.
Type:
Grant
Filed:
November 15, 2017
Date of Patent:
December 7, 2021
Assignees:
Tokyo University of Science, National University Corporation Chiba University, JEOL Ltd.
Abstract: Novel means that enables prediction of prognosis of a patient with cancer or inflammatory disease is disclosed. In the method for prediction of prognosis of a patient with cancer or inflammatory disease according to the present invention, the expression level of the FROUNT gene in a sample collected from the patient is measured. Since FROUNT is a poor prognostic factor, the lower the expression level of the FROUNT gene is, the better the prognosis in the patient is predicted to be. Or, the expression level of the CC chemokine receptor/ligand gene in a sample collected from the patient is measured. Since the CC chemokine receptor/ligand gene such as CCR2 or CCR5 is a good prognostic factor, the higher the expression level of the CC chemokine receptor/ligand gene is, the better the prognosis in the patient is predicted to be.