Abstract: A heat radiator for an aircraft, which cools a heat source installed in the aircraft, includes a heat radiating part in which a contact surface comes into contact with a main flow, the contact surface being formed with a concave portion or a convex portion in which a surface thereof directed upstream in a flow direction of the main flow is curved in a plan view.
Type:
Grant
Filed:
April 9, 2019
Date of Patent:
August 3, 2021
Assignees:
IHI Corporation, National University Corporation Tokyo University of Agriculture and Technology
Abstract: The purpose of the invention is to develop a novel therapeutic agent for fatty liver diseases such as NASH or NAFLD. The invention provides a therapeutic or prophylactic agent for fatty liver diseases that comprises, as an active ingredient, a compound represented by formula (I) or a pharmaceutically acceptable salt thereof. The invention also provides a therapeutic or prophylactic agent for adiposity that comprises, as an active ingredient, a compound represented by formula (I) or a pharmaceutically acceptable salt thereof.
Type:
Grant
Filed:
August 6, 2018
Date of Patent:
July 27, 2021
Assignees:
Hiroshima University, Tokyo University of Pharmacy & Life Sciences, The University of Tokyo
Abstract: An optical pulse pair generator is configured to generate an optical pulse pair including a first pulse beam and a second pulse beam having respective central wavelengths that are separated by a predetermined wavelength difference from each other and having target time waveforms that are substantially the same as each other. The optical pulse pair generator provided includes a splitter section configured to split an incident pulse beam into two, a first shaping section configured to shape one of the pulse beams split by the splitter section by shaping into the target time waveform and setting a central frequency so as to configure the first pulse beam, and a second shaping section configured to shape the other of the pulse beams split by the splitter section by shaping into the target time waveform so as to configure the second pulse beam.
Type:
Application
Filed:
April 19, 2019
Publication date:
July 15, 2021
Applicant:
National University Corporation Tokyo University of Agriculture and Technology
Abstract: A Ras protein degradation inducing molecule that can induce degradation of Ras proteins, and a pharmaceutical composition that contains this Ras protein degradation inducing molecule are provided. The Ras protein degradation inducing molecule is a conjugate of a Ras protein affinity molecule which has affinity to Ras proteins, and a proteolysis-inducing tag which has affinity to protease and does not inhibit proteolysis of proteins by the protease.
Abstract: A sleepiness level prediction device includes a vehicle information acquisition unit, a driver information acquisition unit, and a control unit. The vehicle information acquisition unit is configured to acquire information relating to a vehicle. The driver information acquisition unit is configured to acquire information relating to a driver. The control unit is configured to calculate a stimulus amount to be given to the driver based on a current driving load of the driver and a driving load after a prescribed time, based on the information relating to the vehicle, calculate a non-acclimation degree indicative of a level at which the driver is not acclimated to driving based on a change in the stimulus amount, and predict a sleepiness level of the driver after the prescribed time based on a current sleepiness level of the driver estimated based on the information relating to the driver and the non-acclimation degree.
Type:
Grant
Filed:
October 3, 2018
Date of Patent:
June 22, 2021
Assignees:
Marelli Corporation, University Corporation Tokyo University Of Agriculture And Technology
Abstract: A p53 degradation inducing molecule which can induce degradation of p53 proteins or p53 composites, and a pharmaceutical composition containing said p53 degradation inducing molecule are provided. This p53 degradation inducing molecule is a conjugate of a p53 affinity molecule which has affinity for p53 proteins or p53 composites, and a proteolysis induction tag which has affinity for protease and which does not inhibit proteolysis of proteins by protease.
Abstract: A liquid jet discharge device including an ejection section, a pressure generation section, and an impulse force impartation means. The ejection section is open at both end portions and internally houses a liquid such that a contact angle between the liquid and at least an inner face of the ejection section is less than 90°. The pressure generation section is in communication with one end portion of the ejection section, has a cross-sectional area larger than a cross-sectional area of the ejection section, has a length in a discharge direction of a liquid jet that is longer than a length in the discharge direction from the one end portion of the ejection section to a surface of the liquid, and houses the liquid at least at a bottom face side onto which the one end portion opens. The impulse force impartation means is configured to impart an impulse force to the pressure generation section.
Type:
Application
Filed:
June 20, 2019
Publication date:
May 13, 2021
Applicants:
National University Corporation Tokyo University of Agriculture and Technology, Kishu Giken Kogyo Co., Ltd.
Abstract: A semiconductor substrate that is used as an underlying substrate for epitaxial crystal growth carried out by the HVPE method includes a ?-Ga2O3-based single crystal, and a principal plane that is a plane parallel to a [100] axis of the ?-Ga2O3-based single crystal. An epitaxial wafer includes the semiconductor substrate, and an epitaxial layer including a ?-Ga2O3-based single crystal and formed on the principal plane of the semiconductor substrate by epitaxial crystal growth using the HVPE method. A method for producing an epitaxial wafer includes by using the HVPE method, epitaxially growing an epitaxial layer including a ?-Ga2O3-based single crystal on a semiconductor substrate that includes a ?-Ga2O3-based single crystal and has a principal plane parallel to a [100] axis of the ?-Ga2O3-based single crystal.
Type:
Grant
Filed:
November 16, 2016
Date of Patent:
April 20, 2021
Assignees:
Tamura Corporation, National University Corporation Tokyo University of Agriculture and Technology
Inventors:
Ken Goto, Yoshinao Kumagai, Hisashi Murakami
Abstract: Provided are: a protein degradation inducing tag which is a molecule that has affinity with proteases and does not inhibit degradation of a protein by proteases; a protein degradation inducing molecule that is a conjugate of at least one protein degradation inducing tag and at least one protein binding molecule that binds to a protein; and a usage of those.
Abstract: Provided are: a protein degradation inducing tag which is a molecule that has affinity with proteases and does not inhibit degradation of a protein by proteases; a protein degradation inducing molecule that is a conjugate of at least one protein degradation inducing tag and at least one protein binding molecule that binds to a protein; and a usage of those.
Abstract: Disclosed is a method for determining the sex of yellowtails, the method comprising a step of identifying whether an amino acid residue at position 143 in polypeptide encoded by the HSD17B1 gene of yellowtails is a glutamic acid residue or a glycine residue; a nucleic acid molecule or a primer set which is for use in said method; or a kit comprising the same, for determining the sex of yellowtails. The method according to the present invention is useful in that the genetic sex of yellowtails can be accurately determined.
Type:
Application
Filed:
February 18, 2019
Publication date:
February 4, 2021
Applicant:
National University Corporation Tokyo University of Marine Science and Technology
Abstract: In a control device for a switched reluctance motor, a voltage drop control is executed in which a voltage dropped to be lower than a voltage applied in a case where the switched reluctance motor is driven in a high-load region is applied to the switched reluctance motor, in a case where the switched reluctance motor is driven in a low-load region. The low-load region is a lower load region than the high-load region.
Type:
Grant
Filed:
October 2, 2017
Date of Patent:
February 2, 2021
Assignees:
TOYOTA JIDOSHA KABUSHIKI KAISHA, Tokyo University of Science Foundation
Abstract: A sheet-type metamaterial includes: a film-shaped dielectric substrate; a first and second wire array formed on the dielectric substrate's front surface and back surface respectively. The first wire array includes elongated metallic first cut wires of a length aligned in a y-axis direction with a gap g therebetween and in an x-axis direction with space s therebetween. The second wire array includes second cut wires having the same shape as first cut wires and aligned so as to overlap first cut wires and to be symmetric with the first cut wires. With a design frequency set at 0.51 THz, the dielectric substrate's thickness d is set at about 50 ?m, space s is set at about 361 ?m, gap g is set at about 106 ?m, and the length of first and second cut wires is set at a length approximate to a value to generate resonance at a working frequency.
Type:
Grant
Filed:
February 7, 2017
Date of Patent:
January 26, 2021
Assignee:
National University Corporation Tokyo University of Agriculture and Technology
Abstract: Provided are stereoscopic eyeglasses capable of reducing visual fatigue in binocular stereoscopic display by a simple configuration. In stereoscopic eyeglasses, in order to expand a tolerance of match between vergence and accommodation enabling comfortable stereovision in eyeglasses-using stereoscopic display, wide-focus lenses ranging in focal length are incorporated so as to overlap optical filters in light transmission directions, and accordingly, visual fatigue to be caused by vergence-accommodation conflict during stereoscopic image observation is reduced.
Type:
Application
Filed:
June 7, 2019
Publication date:
January 14, 2021
Applicants:
National University Corporation Tokyo University of Agriculture and Technology, Itoh Optical Industrial Co., Ltd.
Abstract: The purpose of the invention is to develop, as drug-candidate compounds, a group of novel compounds having the activity of inhibiting functions of Pin1. The invention provides: a compound represented by formula (I) or a salt thereof; and a Pin1 inhibitor, a pharmaceutical composition, a therapeutic or prophylactic agent for inflammatory diseases, a therapeutic or prophylactic agent for cancer, and a therapeutic or prophylactic agent for adiposity that use said compound/salt.
Type:
Application
Filed:
August 6, 2018
Publication date:
December 10, 2020
Applicants:
Hiroshima University, Tokyo University of Pharmacy & Life Sciences, The University of Tokyo
Abstract: The purpose of the invention is to develop, as drug-candidate compounds, a group of novel compounds having the activity of inhibiting functions of Pin1. The invention provides: a compound represented by formula (I) or a salt thereof; and a Pin1 inhibitor, a pharmaceutical composition, a therapeutic or prophylactic agent for inflammatory diseases, a therapeutic or prophylactic agent for cancer, and a therapeutic or prophylactic agent for adiposity that use said compound/salt.
Type:
Application
Filed:
August 6, 2018
Publication date:
December 10, 2020
Applicants:
Hiroshima University, Tokyo University of Pharmacy & Life Sciences, The University of Tokyo
Abstract: The purpose of the invention is to develop a novel therapeutic agent for fatty liver diseases such as NASH or NAFLD. The invention provides a therapeutic or prophylactic agent for fatty liver diseases that comprises, as an active ingredient, a compound represented by formula (I) or a pharmaceutically acceptable salt thereof. The invention also provides a therapeutic or prophylactic agent for adiposity that comprises, as an active ingredient, a compound represented by formula (I) or a pharmaceutically acceptable salt thereof.
Type:
Application
Filed:
August 6, 2018
Publication date:
December 10, 2020
Applicants:
Hiroshima University, Tokyo University of Pharmacy & Life Sciences, The University of Tokyo
Abstract: The present invention provides a means capable of selectively introducing a disulfide bond with respect to two free thiol groups located in a molecule of an organic compound such as a peptide, or the like, in a short time by a simple treatment and also by a chemically stable method. A nitrogen-containing compound represented by Chemical Formula 1 below or a salt thereof: The symbols shown in Chemical Formula 1 are the same as defined in the specification.
Type:
Grant
Filed:
May 22, 2017
Date of Patent:
November 10, 2020
Assignees:
Tokyo University of Pharmacy & Life Sciences, Kokusan Chemical Co., Ltd.
Abstract: A driving assistance control apparatus of a vehicle includes a blind area detector, a driving operation detector, and an electronic control unit. The blind area detector is configured to detect the presence or absence of a blind area as seen from the vehicle in a traveling direction of the vehicle. The driving operation detector is configured to detect driving operation of the driver. The electronic control unit is configured to perform automatic deceleration control of the vehicle based on detection of the presence of the blind area by the blind area detector. The electronic control unit is configured to start the automatic deceleration control, by referring to the driving operation of the driver after detection of the presence of the blind area by the blind area detector.
Type:
Grant
Filed:
May 5, 2017
Date of Patent:
October 20, 2020
Assignees:
TOYOTA JIDOSHA KABUSHIKI KAISHA, National University Corporation Tokyo University of Agriculture and Technology, THE UNIVERSITY OF TOKYO