Abstract: A therapeutic effect of irinotecan is predicted using a predetermined genetic polymorphism. A genetic polymorphism identified by rs1980576 in APCDD1L gene, or a genetic polymorphism in linkage disequilibrium with the above genetic polymorphism is analyzed, and determination is performed based on the genotype of the genetic polymorphism.

Abstract: Provided is a resin film for laminating a metal plate comprising a resin composition including a polyester-based thermoplastic elastomer and a thermoplastic polyester having a glass transition temperature (Tg) of 70° C. or more and 90° C. or less where the thermoplastic elastomer is dispersed in the thermoplastic polyester, wherein a content of the thermoplastic elastomer in the film is 2 to 50 wt %, and an absolute value ?Tg of a difference between a glass transition temperature of the thermoplastic polyester and a glass transition temperature of the film satisfies the following Expression (1): ?Tg<0.5×W??(1) wherein W represents the thermoplastic elastomer content (wt %) in the film.

Abstract: This invention provides a roll-bonded laminate that is excellent in press workability and/or a roll-bonded laminate with improved performance and ease of handling at the time of production. More specifically, this invention relates to a roll-bonded laminate composed of a stainless steel layer and an aluminum alloy layer with the peel strength of 60 N/20 mm or higher, a roll-bonded laminate composed of a stainless steel layer and a pure aluminum layer with the peel strength of 160 N/20 mm or higher, and a roll-bonded laminate composed of a pure titanium or titanium alloy layer and an aluminum alloy layer with the peel strength of 40 N/20 mm or higher.

Abstract: This invention provides a roll-bonded laminate that is excellent in press workability and/or a roll-bonded laminate with improved performance and ease of handling at the time of production. More specifically, this invention relates to a roll-bonded laminate composed of a stainless steel layer and an aluminum alloy layer with the peel strength of 60 N/20 mm or higher, a roll-bonded laminate composed of a stainless steel layer and a pure aluminum layer with the peel strength of 160 N/20 mm or higher, and a roll-bonded laminate composed of a pure titanium or titanium alloy layer and an aluminum alloy layer with the peel strength of 40 N/20 mm or higher.

Abstract: A surface-treated metal plate including: a metal plate; and a nickel-cobalt binary alloy layer formed on the metal plate. When a part having a content ratio of oxygen atoms of 5 atomic % or more as measured by X-ray photoelectron spectroscopic analysis is an oxide coating film, the nickel-cobalt binary alloy layer contains the oxide coating film with a thickness of 0.5 to 30 nm on a surface thereof, and when a pressure cooker test including temperature increasing, retention for 72 hours under a water-vapor atmosphere at a temperature of 105° C. and a relative humidity of 100% RH, and temperature decreasing is performed, the amount of increase in the thickness of the oxide coating film is 28 nm or less.

Abstract: Provided is a sulfide all-solid battery having an anode current collector of powerful adhesiveness which is difficult to be sulfurized. The sulfide all-solid-state battery including: a cathode layer; an anode layer; and a sulfide solid electrolyte layer disposed between the cathode layer and the anode layer, wherein the anode layer has an anode mixture layer, and an anode current collector on a face of the anode mixture layer, the face being on an opposite side of the sulfide solid electrolyte layer, the anode current collector is electrolytic iron foil that does not substantially contain other elements, and the anode current collector has surface roughness Ra of 0.2 ?m to 0.6 ?m, and surface roughness Rz of 2 ?m to 6 ?m.

Abstract: A surface-treated steel sheet for battery cases is provided which comprises a nickel-cobalt alloy layer formed at the outermost surface of a plane to be an inner surface of a battery case, wherein a Co/Ni value at the surface of the nickel-cobalt alloy layer is within a range of 0.1 to 1.5 as determined by Auger electron spectroscopy analysis.

Abstract: Provided are a thin hard disk substrate that is scratch-resistant on the disk surface and wobbles less during rotation and a hard disk device including such a hard disk substrate. The hard disk substrate 1 includes an aluminum alloy substrate 2 having NiP plating films 3 on the surfaces. The aluminum alloy substrate 2 has the Vickers hardness of 60 Hv or more, the ratio between the thickness of the NiP plating films 3 and the thickness of the Al alloy substrate 2 is 3.8% or more, the Young's modulus of the hard disk substrate 1 is 74.6 GPa or more, and the Vickers hardness of the hard disk substrate 1 is 293 Hv or more.

Abstract: A surface-treated steel sheet for a battery container, including a steel sheet, an iron-nickel diffusion layer formed on the steel sheet, and a nickel layer formed on the iron-nickel diffusion layer and constituting the outermost layer, wherein when the Fe intensity and the Ni intensity are continuously measured from the surface of the surface-treated steel sheet for a battery container along the depth direction with a high frequency glow discharge optical emission spectrometric analyzer, the thickness of the iron-nickel diffusion layer being the difference between the depth at which the Fe intensity exhibits a first predetermined value and the depth at which the Ni intensity exhibits a second predetermined value is 0.04 to 0.31 ?m; and the total amount of the nickel contained in the iron-nickel diffusion layer and the nickel contained in the nickel layer is 4.4 g/m2 or more and less than 10.8 g/m2.

Abstract: This invention provides a roll-bonded laminate composed of a hard copper layer and a stainless steel layer, which is sufficient both in radiation performance and strength. A roll-bonded laminate 1A is composed of a copper layer 10A and a stainless steel layer 20A, in which thickness of the roll-bonded laminate 1A is 0.02 mm to 0.4 mm, hardness of the copper layer 10A is 70 Hv or higher, and 180° peel strength of the roll-bonded laminate 1A is 6 N/20 mm or more.

Abstract: In the case of using a blocking nucleic acid to prevent non-specific hybridization of a target nucleic acid with a nucleic acid probe, further excellent efficiency of detecting the target nucleic acid is achieved. A buffer composition used in hybridization of a target nucleic acid with a nucleic acid probe, wherein the buffer composition for hybridization contains a blocking nucleic acid comprising a nucleotide sequence complementary to a region comprising at least a non-detection target nucleotide in a non-target nucleic acid, in a concentration of one or more times higher than the concentration of a nucleic acid in a nucleic acid mixture consisting of the target nucleic acid and the non-target nucleic acid.

Abstract: There is provided a roughened nickel-plated sheet having a roughened nickel layer as an outermost surface layer on at least one surface of a metal base material, wherein the brightness L* of the surface of the roughened nickel layer is 30 to 50, the glossiness of 85° of the surface of the roughened nickel layer is 1.5 to 50.

Abstract: Provided is a technique that allows extensively collecting genome information (specimens) from general persons other than patients, and allows effective utilization of the genome information. A server device provides a genome related service and includes a storage device that stores a program to provide the service and a processor that reads the program from the storage device and executes the program. The processor executes: a process that generates information that can be exchanged for value for predetermined settlement given to a specimen provider as a compensation for providing a specimen; and a process that associates genome information obtained through an analysis of the provided specimen and identification information of the specimen provider with the generated information that can be exchanged for value and stores the associated information in a database (see FIG. 1).

Abstract: [Problem] To provide a laminated electrolytic foil having strength sufficient to successfully suppress tearing or ripping during manufacture, the tearing or ripping being concerned accompanying with a trend toward thinner structures in battery current collectors, and improved in handling properties during the manufacture, and also a battery using the laminated electrolytic foil. [Solution] A laminated electrolytic foil includes a first metal layer formed from Cu and a second metal layer formed from Ni or an Ni alloy, in which the first metal layer and the second metal layer are laminated together. The laminated electrolytic foil has an overall layer thickness, which is the thickness of the laminated electrolytic foil as a whole, of 3 to 15 ?m and tensile strength of 700 MPa or higher.

Abstract: It is intended to conveniently determine the pharmacokinetics of axitinib and to predict the therapeutic effect of axitinib. The present invention provides a method for determining the pharmacokinetics of axitinib, comprising the step of calculating a predicted pharmacokinetic parameter of axitinib using specific gene polymorphisms and background factors regarding a test subject.

Abstract: This invention provides a roll-bonded laminate for an electronic device that exhibits high rigidity and a high elastic modulus and is suitable for housing applications. More specifically, this invention concerns a roll-bonded laminate for an electronic device composed of a stainless steel layer and an aluminum alloy layer, wherein thickness TAl (mm) and surface hardness HAl (HV) of the aluminum alloy layer and thickness TSUS (mm) and surface hardness HSUS (HV) of the stainless steel layer satisfy the correlation represented by Formula (1): HSUSTSUS2?(34.96+0.03×(HAlTAl2)2?3.57×HAlTAl2)/(?0.008×(HAlTAl2)2+0.061×HAlTAl2+1.354). This invention also concerns an electronic device housing.

Abstract: This invention provides a roll-bonded laminate that is excellent in press workability and/or a roll-bonded laminate with improved performance and ease of handling at the time of production. More specifically, this invention relates to a roll-bonded laminate composed of a stainless steel layer and an aluminum alloy layer with the peel strength of 60 N/20 mm or higher, a roll-bonded laminate composed of a stainless steel layer and a pure aluminum layer with the peel strength of 160 N/20 mm or higher, and a roll-bonded laminate composed of a pure titanium or titanium alloy layer and an aluminum alloy layer with the peel strength of 40 N/20 mm or higher.

Abstract: This invention provides a relatively thick roll-bonded laminate that exhibits a high Erichsen value and excellent molding workability. Such roll-bonded laminate is composed of a stainless steel layer and a non-stainless steel metal layer, and it is characterized in that thickness T is 0.2 mm to 3 mm and a correlation between a proportion PSUS of thickness TSUS of the stainless steel layer relative to thickness T and a half width FWHM200 of a peak exhibiting a crystal plane orientation (200) determined by X-ray diffraction analysis of the stainless steel layer side satisfies the correlation represented by the formula: FWHM200?0.0057PSUS+0.4.

Abstract: A surface-treated steel sheet for a battery container, including a steel sheet, an iron-nickel diffusion layer formed on the steel sheet, and a nickel layer formed on the iron-nickel diffusion layer and constituting the outermost layer, wherein when the Fe intensity and the Ni intensity are continuously measured from the surface of the surface-treated steel sheet for a battery container along the depth direction with a high frequency glow discharge optical emission spectrometric analyzer, the thickness of the iron-nickel diffusion layer being the difference between the depth at which the Fe intensity exhibits a first predetermined value and the depth at which the Ni intensity exhibits a second predetermined value is 0.04 to 0.31 ?m; and the total amount of the nickel contained in the iron-nickel diffusion layer and the nickel contained in the nickel layer is 10.8 to 26.7 g/m2.

Abstract: Provided is a surface-treated steel sheet with a compound layer containing F and composed essentially or Zr at least on one surface thereof, wherein the Zr amount is 80 to 350 mg/m2 and the F amount is 0.5 to 10 mg/m2 within the layer, and an organic resin coated metal container manufactured using the surface-treated steel sheet. The surface-treated steel sheet of the present invention is manufactured through forming a layer having the Zr amount of 80 to 350 mg/m2 at least on one surface of a steel sheet by cathode electrolytic treatment in an aqueous solution containing a Zr ion and F ion, and subsequently adjusting the surface to control the F amount to 0.5 to 10 mg/m2 by one or more treatments selected from immersion and spraying with an ion-containing aqueous solution and cathode electrolytic treatment in the ion-containing aqueous solution.