Abstract: A variety of methods, devices, systems and arrangements are implemented involving nanowire meshes. One such method is implemented to include synthesizing metal nanowires in a solution containing a structure-directing agent. The metal nanowires are deposited on a substrate to form a sheet of nanowires. The deposited metal nanowires are heated to a temperature less than about 200 degrees Celsius and for a period of time of about 10 minutes to 60 minutes, thereby removing the structure-directing agent and modifying the electrical conductivity and optical transmittance of the sheet of nanowires.

Abstract: Methods, compositions and articles of manufacture for contributing to the treatment of cancers, including solid tumors, are disclosed. The methods, compositions and articles of manufacture can utilize an endothelin B agonist (ETB) to enhance the delivery and resulting efficacy of a chemotherapeutic agent.

Abstract: Methods and compositions for contributing to the treatment of cancers, especially ovarian tumors, are disclosed. The methods and compositions utilize an endothelin B agonist (ETB) to enhance the delivery and resulting efficacy of chemotherapeutic agent(s) (e.g., cisplatin and/or cyclophosphamide).

Abstract: Methods and devices for preventing a change in the core body temperature of a mammal under cold conditions are provided. In the subject methods, a requirement for thermal energy input in said mammal is first detected. In response to the detection of this requirement for thermal energy input, a surface of a portion of the mammal is contacted with a warm temperature medium under negative pressure conditions for a period of time sufficient to introduce thermal energy into the core body of the mammal. The subject devices include at least a means for detecting a requirement for thermal energy input and a means for contacting a surface of the mammal with a warm temperature medium under negative pressure conditions. The subject methods and devices find use in a variety of applications, and are particularly suited for use in maintaining the core body temperature of a mammal substantially constant under cold conditions for an extended period of time.

Abstract: Transglutaminase inhibitors and methods of use thereof are provided.

Abstract: Compositions and methods for expanding natural T regulatory cells (nTregs) without substantially sacrificing suppressive function of the cells are disclosed. Also provided are uses of the expanded nTregs for cellular therapy.

Abstract: The present invention provides stretchable, and optionally printable, semiconductors and electronic circuits capable of providing good performance when stretched, compressed, flexed or otherwise deformed. Stretchable semiconductors and electronic circuits of the present invention preferred for some applications are flexible, in addition to being stretchable, and thus are capable of significant elongation, flexing, bending or other deformation along one or more axes. Further, stretchable semiconductors and electronic circuits of the present invention may be adapted to a wide range of device configurations to provide fully flexible electronic and optoelectronic devices.

Abstract: The presently disclosed and claimed inventive concept(s) relates generally to packaging materials for packaging articles. The packaging materials may include a substratum with a printed pattern disposed thereon that provides a grass-like appearance, and/or the packaging materials may include a plurality of individual strips, strands, or units of material bondably connected thereto.

Abstract: Methods for prognosis and diagnosis of dysplasia and cancer are disclosed. In particular, the invention relates to the use of the biomarker PERP, a desmosome protein involved in cell adhesion and apoptosis, for aiding diagnosis, prognosis, and treatment of dysplasia and cancer.

Abstract: The present disclosure provides compositions and methods related to the fermentation of xylose. Host cells having recombinant polynucleotides encoding one or more of aldose reductases, xylitol dehydrogenases, and xylulokinase are provided herein. Host cells having reduced expression of PHO13 are also provided herein. Also provided herein are uses of host cells provided herein, and methods relating to the use of xylose-containing materials.

Abstract: Methods and devices for manipulating the thermoregulatory status of a mammal are provided. In the subject methods, thermal energy is transferred between the environment and both of the thoracic/abdominal core body and head of the mammal. In general, thermal energy transfer between thoracic/abdominal core body and the environment occurs under negative pressure conditions. The subject methods and devices can be used to increase the thoracic/abdominal core body temperature of a mammal, in which case thermal energy is introduced into the thoracic/abdominal core body of the mammal and removed from the head of the mammal or cold is merely applied thereto. The subject methods and devices can also be used to reduce the thoracic/abdominal core body temperature of a mammal, in which case thermal energy is removed from the thoracic/abdominal core body of the mammal and introduced into the head of the mammal or heat is merely applied thereto.

Abstract: An optical fiber includes a cladding with a material having a first refractive index and a pattern of regions formed therein. Each of the regions has a second refractive index lower than the first refractive index. The optical fiber further includes a core region and a core ring having an inner perimeter, an outer perimeter, and a thickness between the inner perimeter and the outer perimeter. The thickness is sized to reduce the number of ring surface modes supported by the core ring.

Abstract: The disclosed subject matter relates to systems and methods for preparing epitaxially textured polycrystalline films. In one or more embodiments, the method for making a textured thin film includes providing a precursor film on a substrate, the film includes crystal grains having a surface texture and a non-uniform degree of texture throughout the thickness of the film, wherein at least a portion of the this substrate is transparent to laser irradiation; and irradiating the textured precursor film through the substrate using a pulsed laser crystallization technique at least partially melt the film wherein the irradiated film crystallizes upon cooling to form crystal grains having a uniform degree of texture.

Abstract: Systems and methods for matching a characteristic of multiple sectors of a moving tissue to verify an overlap thereof are disclosed herein. In an exemplary method, tissue data for at least a first sector and a second sector of a moving tissue is acquired. A characteristic of at least a portion of the first and second sectors is estimated from the acquired tissue data, and the estimated characteristics are matched to verify whether a portion of the first sector overlaps with a portion of the second sector. Estimating can include estimating a displacement such as an axial displacement and/or lateral displacements. Estimating can further include estimating a strain, a velocity, a strain rate and/or a stiffness or equivalent.

Abstract: An optical sensor includes at least a portion of an optical waveguide having a hollow core. The optical waveguide substantially confines a first optical signal and a second optical signal within the hollow core as the first optical signal and the second optical signal counterpropagate through the optical waveguide. Interference between the first optical signal and the second optical signal is responsive to perturbation of the at least a portion of the optical waveguide.

Abstract: Methods and compositions for detecting the sub-cellular localization of a molecule are provided. Aspects of the invention include detecting translocation of a cell-surface receptor to a sub-cellular compartment, e.g., the endosome, using a reduced affinity enzyme complementation reporter system. Also provided are systems and kits for use in practicing embodiments of the methods.

Abstract: An pulse electro thermal defrost evaporator system has multiple refrigerant tubes formed from an electrically conductive metal and connected in parallel for refrigerant flow. These tubes are, however, connected electrically in series. A controller is capable of detecting ice accumulation and connecting the tubes to a source of electrical power for deicing when it is necessary to deice the tubes. Embodiments having a manifold having multiple conductive sections insulated from each other are disclosed for coupling tubes electrically in series. Alternative embodiments with a single, long, wide-bore, tube are disclosed, as are embodiments having an evaporating pan coupled in series or parallel with the tubes, and embodiments with thermal cutoff and electrical safety interlocks.

Abstract: Disclosed herein are compositions and methods for combining the output obtained from redundant sensor elements in a sensor array.

Abstract: Detection of toxic gluten oligopeptides refractory to digestion and antibodies and T cells responsive thereto can be used to diagnose Celiac Sprue.

Abstract: Methods are described for slowing or inhibiting the progression of heart failure in a mammalian subject suffering from chronic hypertension. The methods involve administering an ?PKC, ?1PKC, or ?IIPKC peptide inhibitor, examples of which are provided.