Abstract: Systems, methods, and apparatuses provide a scalable framework for analyzing queuing and transient congestion in network switches. The system reports which flows contributed to the queue buildup and enables direct per-packet action in the data plane to prevent transient congestion. The system may be configured to analyze queuing in legacy network switches.

Abstract: Disclosed is a fast-response sensor system to measure a fluid vector in a plurality of dimensions. This system, known as ‘MAST’ (for MEMS Anemometry Sensing Tower), utilizes microelectromechanical (MEMS) hot-wire devices to produce a solid-state, lightweight, and robust flow sensor system suitable for, e.g., real-time wind estimation onboard a UAV. The MAST uses three through eighteen polygonally-arranged microscale flow sensors to determine the fluid's vector's direction and magnitude.

Abstract: Various embodiments comprise systems, methods, architectures, mechanisms, apparatus, and improvements thereof for the processing of text-based content such as from a collection of content items including unstructured and structured text of different formats and types so as to automatically derive therefrom an organized, trend-indicative representation of underlying topics/subtopics within the collection of content items.

Abstract: Provided herein are novel heterocyclic compounds, for example, compounds having Formula I, I-P, II, II-P, III, or IV. Also provided herein are pharmaceutical compositions comprising the compounds and methods of using the same, for example, in inhibiting aldehyde dehydrogenases, retinoid pathway activation, and/or for treating various cancers, cancer metastasis, type 2 diabetes, pulmonary arterial hypertension (PAH) or neointimal hyperplasia (NIH) or as a male contraceptive.

Abstract: Disclosed are criteria for a lattice matched, multilayer, organic crystal heterostructure. Current organic devices (e.g., photovoltaics, light emitting diodes, or transistors) rely on amorphous material despite superior charge transport properties of crystalline organic semiconductors. Achieving a fully crystalline device architecture requires growth of a molecular crystal atop a different one, or heteroepitaxy, and is particularly relevant in organic semiconductor devices that demand multiple layers of different molecules. This challenge is complicated when attempting to stack highly ordered layers needed for crystalline devices because strategies are needed to ensure that each layer grows crystalline. It is shown herein that lattice matching alone is not sufficient for successful organic heteroepitaxy deposited via physical vapor deposition.

Abstract: A load modulated balanced amplifier (LMBA) circuit can include an input pad of the LMBA circuit configured to receive an input signal on a semiconductor die. A transformer-based hybrid splitter can be coupled to the input pad and configured to provide a first split input signal and a second split input signal from the input signal. A control power amplifier circuit coupled the first split input signal and a power amplifier circuit coupled to the second split input signal.

Abstract: A system and method for controlling metabolic enzymes or pathways in cells to produce a chemical above the levels of a wild-type strain is disclosed. The system utilizes cells, including yeasts, bacteria, and molds, having at least two genes capable of being controlled bi-directionally with light, where one gene is turned from off to on when exposed to light and another gene is turned from on to off when exposed to light, the two genes reversing when the light is turned off. Cells may utilize any number of sequences that benefit chemical production, including sequences that: encode for constitutive transcription of light-activated transcription factor fusions; encode for a metabolic enzyme; encode for a repressor; induce expression of metabolic enzymes; and an endogenous or exogenous activator expressed by a constitutive promoter, inducible promoter, or gene circuit.

Abstract: A system and method for chat-based studies utilizing a plurality of users may be provided, utilizing at least one chat room processor and a plurality of remote processors. The chat room processors may be configured to receive a chat room template, create a plurality of chat rooms based on the chat room template, assign participants to one chat rooms, provide instructions associated with the chat room when all participants are present, provide questions or prompts at times defined by the chat room template or when conditions defined by the chat room template are met, collect all messages received from each participant, and storing information that includes the message, a time stamp the message was sent and/or received, and at least one unique identification code associated with the participant sending the message.

Abstract: Methods, devices, and systems are described for performing quantum operations. An example device at least one magnetic field source configured to supply an inhomogeneous magnetic field, at least one semiconducting layer, and one or more conducting layers configured to: define at least two quantum states in the at least one semiconducting layer, and cause, based on an oscillating electrical signal supplied by the one or more conducting layers, an electron to move back and forth between the at least two quantum states in the presence of the inhomogeneous magnetic field. The movement of the electron between the at least two quantum states may generate an oscillating magnetic field to drive a quantum transition between a spin-up state and spin-down state of the electron thereby implementing a qubit gate on a spin state of the electron.

Abstract: There is currently a high demand for new therapeutic antibiotics with new mechanisms of action. Disclosed are two small molecules, tryglysin A and B, with novel chemical structures and potent antibiotic activity against a narrow spectrum of bacteria. This narrow spectrum of activity indicates the tryglysins could be working through a novel antibiotic mechanism of action. Due to this narrow spectrum, the tryglysins could be used as highly targeted therapeutics to treat or prevent disease without disturbing other important, “beneficial” bacteria within the human microbiome, which is a great improvement over virtually all other clinically used antibiotics that are broad-spectrum. The tryglysins are potent against several streptococcal pathogens, including Streptococcus pneumonia, the leading cause of pneumonia, and Streptococcus mutans, the primary causative agent of tooth decay and gum disease.

Abstract: Devices and systems are disclosed that utilize single-eye virtual reality adapters. The single-eye virtual reality adapter may include a body and a VR lens. The body may be configured to be disposed around a display screen. The body may have an inner surface and an outer surface, separated by a first sidewall and a second sidewall. The body may define a lens opening extending from the outer surface to the inner surface. The body may define a display opening extending from the first sidewall to the second sidewall (e.g., to slidably receive a display screen through the display opening). The VR lens may be removably coupled to the body. The VR lens may be disposed within the lens opening. The VR lens configured to prevent the lens from contacting the display screen; for example, the VR lens may be positioned at a distance d1>0 in front of the display screen.

Abstract: Disclosed are techniques to mimic turbulent-enhanced reactivity under confinement by the addition of dilute high molecular weight polymers. Micro-scale imaging within a transparent porous medium reveals an elastic instability (EI), which drives chaotic fluctuations that stretch and fold solute blobs exponentially in time analogous to turbulent Batchelor mixing, despite the low Re. A reduction in the required mixing length can be observed, suggesting a cooperation between the elastic instability and the dispersion inherent to the disordered 3D porous media—which can be modeled as additive independent mixing rates, representing a dramatic conceptual simplification. The disclosed enhanced transport of solutes circumvents the traditional trade-off between throughput and reactor length, allowing a simultaneous large reduction in length and increases in throughput.

Abstract: Described are systems and assays that monitor presence and/or quantity of herpesviruses viral proteins. Embodiments offer accurate detection and quantification of viral proteins from all temporal classes of viral replication. Three exemplary assays provide specific detection of: herpes simplex vims type 1 (HSV1), human cytomegalovirus (HCMV), and Kaposi's sarcoma-associated herpesvirus (KSHV). These assays can be utilized in combination with drug treatments, genetic modifications, or other perturbations to assess the impact of the intervention on viral protein production.

Abstract: A first product may be provided that comprises a substrate having a first surface, a first side, and a first edge where the first surface meets the first side; and a device disposed over the substrate, the device having a second side, where at least a first portion of the second side is disposed within 3 mm from the first edge of the substrate. The first product may further comprise a first barrier film that covers at least a portion of the first edge of the substrate, at least a portion of the first side of the substrate, and at least the first portion of the second side of the device.

Abstract: Transparent UV-absorbing solar cells are promising for the applications of powering electrochromic windows that regulate the transmission of visible and near-infrared photons for natural lighting and heating purposes, respectively. Current technologies focus on using organic solar cells for the application due to their narrow excitonic absorption and tunable bandgaps. However, transparent organic solar cells have drawbacks including the stability issue and thickness-induced problems, such as low yield rate and limited power conversion efficiency. Disclosed herein is the co-deposition of two or more materials by thermal evaporation to make visibly transparent inorganic perovskite films. By tuning the halide compositions, the inorganic perovskite films show absorption range in UV and near-UV region, which is well-suited to the application. Its high conductivity and absorbance enable it to be around 400 nm thick for devices, which is critical to improve the yield rate and efficiency.

Abstract: Disclosed herein is an all-in-one methodology for the fabrication and the programming of soft machines. Instead of relying on the assembly of individual parts, the disclosed approach harnesses interfacial flows in elastomers that progressively cure to robustly produce monolithic pneumatic actuators whose shape can easily be tailored to suit applications ranging from artificial muscles to grippers. Rationalized herein are the fluid mechanics at play in the assembly of the disclosed actuators and modeled herein are their subsequent morphing. This quantitative knowledge was leveraged to program these soft machines and produce complex functionalities, for example sequential motion obtained from a monotonic stimulus.

Abstract: According to various embodiments, a method for detecting security vulnerabilities in a fifth generation core network (5GCN) is disclosed. The method includes constructing an attack graph from a plurality of regular expressions. Each regular expression corresponds to a sequence of system level operations for a known 5GCN attack. The method further includes performing a linear search on the attack graph to determine unexploited 5GCN attack vectors where path in the attack graph that does not represent a known 5GCN attack vector represents an unexploited 5GCN attack vector. The method also includes applying a trained machine learning module to the attack graph to predict new 5GCN attacks. The trained machine learning module is configured to determine a feasibility of linking unconnected nodes in the attack graph to create a new branch representing a new 5GCN vulnerability exploit.

Abstract: According to various embodiments, a microfluidic bio-sensing system is disclosed. The system includes at least one semiconductor chip configured to control at least one of electrokinetic fluid flow, cell manipulation and sensing, and bio-molecular sensing by utilizing at least one plurality of electrodes in a microfluidic channel. The bio-sensing system is applicable to general bio-molecular and cell-based diagnostics in a battery-powered hand-held ultra-compact packaging without requiring any external instrumentations, allowing for the elimination of pneumatic pumps.

Abstract: A system and method for neurobehavioral testing, including eyeblink conditioning and prepulse inhibition, without air puffs, that utilizes an electronic device with a light source, a camera, and a speaker, and makes assessments based on the degree to which an eyelid is closed after a user is exposed to conditional and unconditional stimuli.

Abstract: Disclosed is a method for wet chemical functionalization of single crystal diamond surfaces that involves gentle reaction conditions. This method enables a wide range of functional groups and molecules to be tethered to the diamond surface. The method is compatible with the formation of stable nitrogen vacancy centers with long spin coherence times within nanometers of the diamond surface.