Abstract: Systems and methods for computer-implemented patient assistance are disclosed. In certain embodiments, the invention contemplates receiving patient data from plurality of sensors at a patient computer, transmitting patient data to a server, monitoring and analyzing the patient data at the server, and outputting recommended actions from the server to a personnel computer. The recommended actions are calculated based on safety considerations, emotional considerations, and/or a patient's treatment plan.

Abstract: Polymer-based selective radiative cooling structures are provided which include a selectively emissive layer of a polymer or a polymer matrix composite material. Exemplary selective radiative cooling structures are in the form of a sheet, film or coating. Also provided are methods for removing heat from a body by selective thermal radiation using polymer-based selective radiative cooling structures.

Abstract: The present invention relates to a leak detection method for GIS based on vibration signals and belongs to the technical field of apparatus for detecting or reacting mechanical or electrical troubles. The method is carried out by the following steps: 1) Installing a vibration sensor on each connecting flange of each gas-tight chamber of the GIS; 2) Starting the GIS; 3) Acquiring the vibration signals of sensors when the GIS operation is stable after starting; 4) Doing de-noise processing on the collected vibration signal; 5) Doing 4-layer wavelet packet decomposition of the vibration signal after noise reduction to obtain the energy proportion of the vibration signal in each frequency band; 6) Analyzing the energy proportion of the vibration signal in each frequency band in step 5), Then alarm to notify the relevant personnel. Return to step 3) until the fault has been solved.

Abstract: Disclosed herein are isotopically labeled calcofluor derivatives and uses of such to detect fungi, such as filamentous fungi, including Aspergillus species, such as by positron emission tomography (PET) scanning.

Abstract: Provided is a leak-proof lubrication system for a power device, comprising an oil supply pump inlet pipe, an oil supply pump, an oil supply pressure gauge, an oil supply pump outlet pipe, an oil supply filter, a lubricating oil, an oil storage tank, an oil return pipe, an storage tank pressure gauge, a vacuum pump intake pipe, a vacuum pump inlet air filter, a vacuum pump and a vacuum pump exhaust pipe. The system employs a negative pressure operation method in which the pressure of the lubrication system is controlled to be lower than the outside ambient pressure, which allows a small amount of air to flow from the outside to the inside of the lubrication system along with the lubricant to return to the storage tank, preventing leakage of the lubricant from connection joints. It is suitable to be used for gas turbines or other high-speed power machines.

Abstract: A method for predicting fishing access of Katsuwonuspelamis purse seine fishery in the Central and Western Pacific adopts the statistical data per year before the forecast year to the previous 16 years, including year, month, longitude, latitude, fishing effort (the number of nets) and the catch (ton) in an important operation waters of 5°S-5°N, 125°E-180°E, a sea surface temperature anomaly (SSTA) in the Nino3.4 area and the sea surface temperature (SST) in the operation waters. A sea area is denoted by 5°×5° spatial resolution, the production statistical data of the sea areas are matched with the corresponding environmental data one by one to obtain the relationship between different SSTA and SST ranges of each sea area and the corresponding initial value fishing effort, a fishing access prediction model of each sea area is established by using a normal distribution model.

Abstract: The invention relates to inhibitory nucleic acids and rAAV-based compositions, methods and kits useful for treating Amyotrophic Lateral Sclerosis.

Abstract: The present invention provides, among other aspects, functionalized chromophoric polymer dots comprising a hydrophobic core and a hydrophilic cap, and bioconjugates thereof. Also provided are improved methods for preparing functionalized chromophoric polymer dots. Methods for in vivo imaging and molecular labeling are also disclosed.

Abstract: A hot wire anemometer circuit has a calibrate subcircuit and an operate subcircuit which are selectively invoked via a user-activate mode switch. The calibrate subcircuit includes a detector configured to compare an amplified sensor voltage with an amplified drive voltage and output an indicator signal when the two voltages match. The drive voltage is derived from a user-adjusted drive resistance of a bridge subcircuit. The operate circuit includes a feedback loop which provides a signal to a bride node of a bridge circuit. After a sensor is connected to the anemometer circuit, the drive resistance is adjusted until the indicator signal is produced, signifying that the circuit is tuned and impedances are matched to prevent oscillations. A slewing network protects the sensor by shorting the drive resistance upon switching the anemometer circuit to the calibrate mode from the operate mode, and gradually restoring the drive resistance when switching back.

Abstract: A pharmaceutical composition with a peptide analog of apelin, and a method of treatment for various conditions are described. An exemplary embodiment is a peptide analog comprising at least residues 2-13 of SEQ ID NO: 1 and further comprising at least a substitution or modification at residue 13 of SEQ ID NO: 1. A pharmaceutical composition comprising the peptide analog of the present invention and method of treatment for diabetes, stimulating insulin release, and moderating blood glucose excursions by administering the peptide analog of the present invention to a patient in need thereof are described.

Abstract: The present invention relates to a filter assembly for a medical image signal and a dynamic decimation method using the same. The filter assembly includes a decimation filter that includes an integer number of multiplier accumulators (MACs), changes a cut-off frequency depending on a bandwidth of the medical image signal received through a dynamic impulse response update, and performs a decimation with respect to the received signal according to a decimation ratio, wherein the decimation filter determines a filter coefficient corresponding to an integer interval so as to up-sample the received medical image signal and supplies the filter coefficient to the MACs.

Abstract: A metal oxide semiconductor carbon nanotube thin film transistor circuit includes a p-type carbon nanotube thin film transistor and a n-type carbon nanotube thin film transistor stacked with each other. The p-type carbon nanotube thin film transistor includes a first semiconductor carbon nanotube layer, a first drain electrode, a first source electrode, a functional dielectric layer, and a first gate electrode. The n-type carbon nanotube thin film transistor includes a second semiconductor carbon nanotube layer, a second drain electrode, a second source electrode, a first insulating layer, and a second gate electrode. The first drain electrode and the second drain electrode are electrically connected with each other. The first gate electrode and the second gate electrode are electrically connected with each other.

Abstract: Provided are inhibitors of Rho GTPase activation, and, in particular, compounds that inhibit RhoA activation by an RhoGEF. Also provided are related pharmaceutical compositions and methods. Also provided are methods of inhibiting Rho GTPase activation. Also provided are methods of screening for compounds that inhibit Rho GTPase activation by a RhoGEF.

Abstract: Kits, methods and systems for providing a service to provide a subject with information regarding the state of a subject's DNA damage. Collection, processing and analysis of samples are also described.

Abstract: We disclose a composition comprising an echogenic liposome (ELIP) having an exterior surface, an interior surface, and at least one bilayer comprising at least one lipid selected from the group consisting of saturated phospholipids, unsaturated phospholipids, mixed phospholipids, and cholesterol, and a thrombolytic compound trapped by the ELIP. We also disclose a method of treating a medical condition in a patient characterized by a thrombus in the patient's vasculature, comprising administering to the patient the composition in an amount effective to reduce the size of the thrombus.

Abstract: Methods and compositions are provided for treatment of disorders associated with aberrant adrenal cortex cell behavior, including (but not limited to) treatment of adrenocortical carcinoma (ACC), Cushing's syndrome and/or pituitary ACTH excess (Cushing's Disease). Such methods involve administration of an effective amount N-(2,6-bis(1-methylethyl)phenyl)-N?-((1-(4-(dimethyl amino)phenyl)cyclopentyl)-methyl)urea hydrochloride to the patient.

Abstract: At least one tactile sensor includes an insulating layer and a conductive layer formed on the surface of the insulating layer. The conductive layer defines at least one group of flexible projections extending orthogonally from the surface of the insulating layer. The flexible projections include a major projection extending a distance orthogonally from the surface and at least one minor projection that is adjacent to and separate from the major projection wherein the major projection extends a distance orthogonally that is greater than the distance that the minor projection extends orthogonally. Upon a compressive force normal to, or a shear force parallel to, the surface, the major projection and the minor projection flex such that an electrical contact resistance is formed between the major projection and the minor projection. A capacitive tactile sensor is also disclosed that responds to the normal and shear forces.

Abstract: A piezoelectric, poly (?-benzyl-?,L-glutamate) (“PBLG”) planar microphone, and method for construction thereof, are disclosed. The microphone includes at least a polyester film, a piezoelectric, hot pressed poly (?-benzyl-?,L-glutamate) (“HPPBLG”) layer, and an aluminum coating for the HPPBLG layer. The coated HPPBLG layer is coupled to the polyester film.

Abstract: A method of modulating hematopoietic stem cells and hematopoiesis includes administering to a subject in need thereof a 15-PGDH inhibitor.

Abstract: Described herein are methods of preventing, arresting progression of or ameliorating vision loss and other conditions associated with retinitis pigmentosa and x-linked retinitis pigmentosa in a subject. The methods include administering to a subject an effective concentration of a composition comprising a recombinant adeno-associated virus (AAV) carrying a nucleic acid sequence encoding a normal retinitis pigmentosa GTPase regulator (RPGR gene), or fragment thereof, under the control of regulatory sequences which express the product of the gene in the photoreceptor cells of the subject, and a pharmaceutically acceptable carrier.