Abstract: The use of extract of leeches' saliva as anti-bacterial agent for the manufacture of different compositions, such as a pharmaceutical composition, a cosmetic composition or a cleaning product.
Type:
Application
Filed:
October 15, 2010
Publication date:
October 4, 2012
Applicants:
UNIVERSITE DE LILLE 1 SCIENCES ET TECHNOLOGIES, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE
Abstract: The present invention relates to the use of compounds with a potentiating effect on the activity of antibiotics that are activatable via the EthA enzymatic pathway, for the preparation of a medicament for preventing and/or treating mycobacterial infections such as tuberculosis and leprosy, to pharmaceutical compositions comprising them in combination with an antibiotic that is activatable via the EthA pathway, to compounds having a potentiating effect on the activity of antibiotics that are activatable via the EthA enzymatic pathway, to pharmaceutical compositions comprising them and to their use as medicaments, especially medicaments for preventing and/or treating mycobacterial infections such as tuberculosis and leprosy.
Type:
Application
Filed:
July 4, 2007
Publication date:
June 9, 2011
Applicants:
Institut Pasteur De Lille, Centre National De La Recherche Scientifique, Universite De Lille 2, Universite Du Droit Et De La Sante, Institut National De La Sante Et De La Recherche Medicale (Inserm)
Inventors:
Benôit Deprez, Nicolas Willand, Dirie Bertrand, Toto Patrick, Villeret Vincent, Locht Camille, Baulard Alain
Abstract: An antigen derived from an intracellular pathogenic micro-organism characterized in that it comprises at least on peptidic fragment which essentially consists of the concatenation of sequences of at least two extracellular adjacent areas in the native structure of a membrane protein of type III of said intracellular pathogenic micro-organism, derived conformational antibodies and the application hereof.
Type:
Grant
Filed:
January 28, 2004
Date of Patent:
September 28, 2010
Assignees:
Centre National de la Recherche Scientifique, Universite de Rouen, Universite de Lille 2
Abstract: The input device (1) comprises a touch-sensitive surface (10a) forming at least one isotonic input area and elastic abutment means (11) forming at least one passive elastic input area that is adjacent to the isotonic input area. A position control is performed in the isotonic input area and a rate control is performed in the elastic area.
Type:
Application
Filed:
October 3, 2008
Publication date:
August 26, 2010
Applicants:
UNIVERSITE DE LILLE-I, UNIVERSITY OF TORONTO
Abstract: The present invention is related to an in vitro diagnostic assay of enteroviruses, based on the revealing of an immunologic reaction of antigen-antibody recognition type, using antigens or epitopes thereof that do not induce antiviral neutralising antibodies but induce “facilitating” antibodies which increase the viral infection.
Type:
Grant
Filed:
February 9, 2004
Date of Patent:
May 19, 2009
Assignees:
Universite de Lille 2 Droit Et Sante, Centre Hospitalier Regional Universitaire de Lille (Chru de Lille)
Inventors:
Wassim Chehadeh, Didier Hober, Ahmed Bouzidi
Abstract: The invention relates to a device for the presentation of polypeptides, a method for the preparation and the use thereof, as diagnostic tool (polypeptide chip) for miniaturized and highly parallel detection of structurally or functionally complementary molecules of said polypeptides, i.e. antibodies.
Type:
Application
Filed:
May 15, 2003
Publication date:
October 18, 2007
Applicants:
Sedac Therapeutics, Centre National De La Recherche Scientifique, Universite De Lille 2
Inventors:
Oleg Melnyk, Xavier Duburcq, Helene Gras-Masse, Christophe Olivier, Fengling Zhou, Claude Auriault, Ahmed Bouzidi
Abstract: The invention concerns a laser photocoagulator comprising a laser emitting at a wavelength within the ICG absorption spectrum and provided with focusing means and a programmed or controlled module powering the laser such that the mean fluence (F) at the focus starting from an initial time varies according to an increasing function in time not varying at any time by more than 10% of an increasing monoexponential corresponding to formula F−F0(1−e−t/r) wherein F is the initial fluence and &tgr; is a time constant ranging between 3 and 5 mn.
Type:
Grant
Filed:
March 8, 2002
Date of Patent:
June 24, 2003
Assignees:
Universite de Lille 2, Centre Hospitalier Regional et Universitaire de Lille
Abstract: A device for simulating a procedure on a simulated organ by an operator, which simulated organ is generated using at least one digitized photograph. The device includes a binocular for observing the organ, fitted with a control stage system, to displace the binocular in an orthonormal triaxial frame. The device further includes means for synthesizing a computer image of the simulated organ, which includes means for simulating a slit lamp, adjusting the dimensioning of the slit lamp, and means for simulating magnifying optics. The device further includes one or two miniaturized video screens, computing means generating the image and projecting it on the screen(s), and means for simulating a lens for examining the organ.
Type:
Grant
Filed:
December 31, 1996
Date of Patent:
June 1, 1999
Assignees:
Universite des Sciences et Techniques de Lille, Centre Hospitalier Regional et Universitaire de Lille, Universite de Lille II
Inventors:
Patrick Dubois, Jean-Francois Rouland, Christophe Chaillou, Sylvain Karpf, Philippe Meseure