Abstract: The present invention is related to a non-human genetically modified mammal comprising a mutation, a partial or total deletion of the genetic sequence encoding the wild type mammal alpha-fetoprotein.

Abstract: A method and device for obtaining a sample with three-dimensional microscopy, in particular a thick biological sample and the fluorescence field emitted by the sample. One embodiment includes obtaining interferometric signals of a specimen, obtaining fluorescence signals emanating from the specimen, recording these signals, and processing these signals so as to reconstruct three-dimensional images of the specimen and of the field of fluorescence emitted by the specimen at a given time.

Abstract: The invention relates to new and known compounds as well as methods for preventing the attachment of aquatic organisms to surfaces which are submerged for extensive periods of time in water. More particularly, this invention relates to the protection of submerged surfaces with new isonitrile, formamide, isocyanate and isothiocyanate anti-fouling agents.

Abstract: The present invention relates to a method for the in vitro preparation of starting materials for micropropagation and/or storage of germplasm, comprising the steps of contacting plant material with a microorganism that induces fasciation and/or one or more fasciation-inducing factors derived from the microorganism or derived from the infected and/or fasciated tissue; developing leafy galls or shoot outgrowths on the plant material; and isolating the leafy galls or shoot outgrowths as the starting materials.

Abstract: The present invention is related to an antibiotic inducible/repressible genetic construct for controlling the transcription of a gene of interes: by a cell. The genetic construct comprises a bi-directional antibiotic controlled activator-responsive promoter/operator sequence which is located between the gene of interest and a cistron encoding a reverse antibiotic controlled transactivator and controls the transcription of the gene of interest and of the cistron.

Abstract: The present invention relates to a device for diagnosing and/or quantifying antibodies present in a biological fluid from a patient and which are specific for a reaction associated with an infection with a microorganism, specific for an autoimmune reaction or specific for an allergy. This device includes as a standard a biological sample selected from a pool of blood plasmas from more than 200 healthy patients.

Abstract: A method measures the three dimensional position of particles in a fluid medium contained in a sample by recording a digital hologram of the particles on an image sensor and by reconstructing the image of the particles from the hologram. The recording includes providing a source beam with a coherent source, and generating at least two beams from the source beam, namely a reference beam and at least one object beam, wherein the reference beam and the object beam are mutually coherent. The sample is illuminated by condensing the object beam onto the sample in order to obtain a scattered object beam for each particle. The scattered object beam is scattered into a spherical converging object beam toward the image sensor for each particle.

Abstract: The invention concerns a pharmaceutical and/or food composition comprising a suitable pharmaceutical and/or food vehicle and a heat shock protein and at least conformation or sequential epitopes of an antigenic structure inducing a graft versus host, an allergic or autoimmune reaction.

Abstract: A cloning and/or sequencing vector enables recombinant clones to be selected directly. The vector encodes a fusion protein which includes a protein poison.

Abstract: A process and a device for synthesizing labeled compounds. The process involves preparing a labeling agent, labeling a precursor with the labeling agent, where the precursor is a protected substrate, and deprotecting the labeled precursor to convert the labeled precursor to a labeled compound by passing the labeled precursor through a solid support in a column or a cartridge. The process may be used to convert labeled tetraacetylfluoroglucose (TAFg) to labeled fluoro-deoxy-glucose (FDG) for use in nuclear medical imaging. The process is more rapid than conventional methods and is performed at room temperature rather than high temperature for conventional technology.

Abstract: The present invention comprises a marker for inflammatory diseases and/or pathologies comprising an autoimmune reaction, which is the plasmatic membrane and/or a portion therof, in particular the plasmatic DNA. The present invention concerns also the method to obtain said marker and the diagnostic device which comprises said marker.

Abstract: Human myeloperoxidase produced by culturing prokaryotic or eukaryotic cells transformed by a vector for the expression of human myeloperoxidase in said cells.

Abstract: A cloning and/or sequencing vector (1) comprises a nucleotide promoter sequence (3) and a nucleotide sequence (4) coding for a fusion protein active as a poison, which nucleotide sequence (4) is obtained by fusion of a coding nucleotide sequence (5) containing several unique cloning sites with a nucleotide sequence (6) coding for a poison protein, wherein the nucleotide sequences (3) and (4) are incorporated in an autonomous replication vector (2).

Abstract: A single-film membrane including at least one hydrophilic interface for breaking water down into is components, and including one or more inorganic compounds. A method for preparing and using the membrane for producing acids and bases, controlling pH and/or electodialyzing and aquous solution, is also provided.

Abstract: Manganese is recovered from its oxides by reacting a manganese oxide with fused calcium chloride or fused magnesium chloride to provide a liquid phase containing manganese chloride and fused chloride, and a solid phase containing reaction residue, the temperature of the reaction being above the melting point of the calcium or magnesium chloride but below the boiling point of manganese chloride in the reaction mixture. The liquid phase containing the manganese chloride is then subjected to electrolysis to deposit manganese metal upon the cathode and release elemental chlorine at the anode.

Abstract: The invention pertains to an aromatic amines synthesis process, fundamentally characterized by the fact that it consists of carrying out the ammonolysis of phenols under pressure in liquid phase by ammonia in aqueous solution.

Abstract: There is described an electrolysis cell which comprises an anode formed by said solid material which contacts directly an anode current supply made of a substantially inert material, said cell being divided into at least one anode compartment and at least one cathode compartment by means allowing the flow of the electrolyte from the cathode compartment to the anode compartment but which however prevent the passage of said solid material from one compartment to another one, other means being provided to cause a substantially continuous flow of electrolyte from the cathode compartment to the anode compartment.

Abstract: A method for recovering manganese metal from ferromanganese is disclosed which comprises:A. contacting ferromanganese and an iron chloride selected from the group consisting of ferrous chloride and ferric chloride in a molten bath of a metal chloride wherein the metal has a greater chemical affinity for chlorine than iron, to provide a liquid phase containing manganese chloride and a solid phase containing iron precipitate;B. separating the manganese chloride liquid phase from the iron precipitate solid phase;C. electrolyzing the manganese chloride liquid phase to provide manganese metal.