Abstract: A pharmaceutical composition has an adequate pharmaceutical carrier or diluent and an element selected from a pharmaceutical composition having an adequate pharmaceutical carrier or diluent and an element selected from: —apolipoprotein apoL-III; —a pharmaceutically active fragment of this apolipoprotein apoL-III; —a nucleotide sequence encoding this apolipoprotein apoL-III or the fragment; —a vector having the nucleotide sequence; —a cell transformed by the nucleotide sequence or the vector; —an inhibitor or activator directed against the apolipoprotein apoL-III, its fragment or its nucleotide sequence, —an anti-inhibitor or anti-activator directed against the inhibitor or activator or its encoding nucleotide sequence.

Abstract: A device and kit for pulsing a biological sample with a pulsing agent is disclosed. The biological sample so pulsed is subsequently stabilized and the device or kit provides a control reaction. Applications for the described device and kit are found in the field of medical diagnostics, particularly immunology.

Abstract: The invention relates to novel benzopyran derivatives of formula I, to their method of production, to composition comprising the derivatives and use thereof.

Abstract: A method and device for obtaining a sample with three-dimensional microscopy, in particular a thick biological sample and the fluorescence field emitted by the sample. One embodiment includes obtaining interferometric signals of a specimen, obtaining fluorescence signals emanating from the specimen, recording these signals, and processing these signals so as to reconstruct three-dimensional images of the specimen and of the field of fluorescence emitted by the specimen at a given time.

Abstract: Gene-Based Algorithmic Cancer Prognosis relates to methods and systems for prognosis determination in tumor samples. The methods and systems measure gene expression in a tumor sample and applying a gene-expression grade index (GGI) or a relapse score (RS) to yield a number c risk score.

Abstract: Compounds and pharmaceutical compositions which include 2? oxo-voruscharin and derivatives are disclosed. The compounds and pharmaceutical compositions are useful in methods of treating cancer, particularly pancreatic cancer.

Abstract: The present invention relates to an in vitro method for differentiation and maturation of isolated monocytes into IL3-R+CD11c+ myeloid dendritic cells consisting of incubating the monocytes with a combination of a type I interferon and IL-3.

Abstract: One aspect of the present invention is related to a quantum cryptographic scheme comprising at least one sending unit including a physical means of encoding and distributing a raw key in the quadrature components of quantum coherent states that are continuously modulated in phase and amplitude, at least one receiving unit containing a physical means of performing homodyne detection of the quantum coherent states in order to measure the quadrature components of the states, a quantum channel for connecting the sending unit to the receiving unit, a two-way authenticated public channel for transmitting non-secret messages between the sending unit and the receiving unit, a quantum key distribution protocol ensuring that the information tapped by a potential eavesdropper can be estimated from the quantum channel parameters, and a direct or reverse reconciliation protocol that converts the raw continuous data into a common binary key.

Abstract: The present invention is related to a compact microscope able to work in digital holography for obtaining high quality 3D images of samples, including fluorescent samples and relatively thick samples such as biological samples, said microscope comprising illumination means (1,41) at least partially spatially coherent for illuminating a sample (2) to be studied and a differential interferometer (5) for generating interfering beams from said sample (2) on the sensor (33) of an electronic imaging device(7), said interferometer (5) comprising namely tilting means (17) for tilting by a defined angle one the interfering beams (28 or 29) relatively to the other, said tilting resulting into a defined shift (27) of said interfering beam on the sensor of the electronic imaging device (7), said shift (27) being smaller than spatial coherence width of each beam, said microscope being able to be quasi totally preadjusted independently from the samples so that minimum additional adjustments are required for obtaining relia

Abstract: A portable medical device for automatically monitoring of electrical activity of target areas inside a patient is described. The medical device is based on a wireless communication network and includes a measuring unit that measures electrical signals at the surface of two target areas and a processing unit connected to the measuring unit. The processing unit includes a slave unit and a master unit for collecting and analyzing the measured electrical signals and presenting the result of the analysis for a clinician. The processing unit also includes a visualization unit connected to the master unit and an optional basic unit for at least presenting the result of the electrical signals and analysis, where the master unit and the basic unit perform an analysis of the electrical signals including an analysis of the coherence between the first and second sets of electrical signals as a function of the monitoring frequency.

Abstract: The present invention is related to a compact microscope able to work in digital holography for obtaining high quality 3D images of samples, including fluorescent samples and relatively thick samples such as biological samples, said microscope comprising illumination means (1,41) at least partially spatially coherent for illuminating a sample (2) to be studied and a differential interferometer (5) for generating interfering beams from said sample (2) on the sensor (33) of an electronic imaging device (7), said interferometer (5) comprising namely tilting means (17) for tilting by a defined angle one the interfering beams (28 or 29) relatively to the other, said tilting resulting into a defined shift (27) of said interfering beam on the sensor of the electronic imaging device (7), said shift (27) being smaller than spatial coherence width of each beam, said microscope being able to be quasi totally preadjusted independently from the samples so that minimum additional adjustments are required for obtaining reli

Abstract: The present invention relates to a system for computer-aided intravenous delivery of anesthetics and/or other drugs to a patient, wherein said system comprises an Infusion Controller that delivers an amount of drug(s) to a patient; possibly a DataLogger Controller with one or more Sensors adapted so as to be coupled to a patient and to generate signals reflecting one or more health conditions or statuses of the patient; a Communication Controller connected with the infusion pumps and/or monitors; a Session Controller that carries out the modeling of anesthesia procedures and is arranged to run a first procedure and to dynamically adapt said first procedure and/or select and run a second procedure based upon one or more of said sensors' output and/or observation from a physician; a Graphic User Interface to display different views of the system and to accept user input; a set of interfaces used to link the Infusion, Datalogger and Session Controllers to views displayed by the Graphical User Interface; a Proces

Abstract: The present invention relates to 2-Pyridinone derivatives, more specifically 5-ethyl-6-methyl-2-pyridinone derivatives, according to general formula I that inhibit human immunodeficiency virus type 1 (HIV-1) replication and are therefore of interest in the treatment of Acquired Immune Deficiency Syndrome (AIDS). The present invention further relates to the synthesis of said compounds and their use, with or without other pharmaceutical agents, in the treatment of AIDS and viral infections by HIV-1.

Abstract: The present invention relates to an appliance for the direct measurement, display, processing and transmission, remotely, of electromyographic signals (EMG) comprising: an electrical stimulator (1) comprising electrodes for the excitation of a peripheral motor nerve; a pair of electrodes (31), for the acquisition of the EMG response at the level of the muscle associated with this peripheral nerve; an acquisition chain (2) driven by a micro-controller (3, 39), presenting means of conditioning of the input signal, comprising at least one differential preamplifier (22, 33), a bandpass filter (25, 34) and an analog/digital converter (ADC) (26, 310), said acquisition chain (2) being linked, via a standardized interface (5), to a computer (4) comprising means of storage (9) and of display of the EMG signals acquired as well as an executable program for effecting the interface with the user (6) and utilizing the data stored; characterized in that the acquisition chain (2) comprises means of automatic adjustment of t

Abstract: The present invention concerns methods for in vitro detection of an infection by Mycobacterium tuberculosis in mammals, and methods for in vitro distinction between mammals infected with Mycobacterium tuberculosis in which the disease is declared (active form) and mammals which are infected but asymptomatic for tuberculosis (latent form), and a method for in vitro distinction between mammals presenting an active form of tuberculosis and mammals not infected by M. tuberculosis or presenting a latent form of tuberculosis. The present invention also pertains to kits for detection and distinction between infected mammals presenting tuberculosis symptoms and infected mammals with no disease development, and a kit for distinguishing between mammals presenting an active form of tuberculosis and mammals not infected by M. tuberculosis or presenting a latent form of tuberculosis.

Abstract: A method and system for handling information in a noisy environment in the form of at least one information carrying mode is disclosed. A plurality of encoded modes are generated by linear transformation of the information carrying mode, said encoded modes being provided on respective independent channels. The encoded modes are linearly combined to generate at least one decoded mode. A set of receiver channels is provided for receiving the decoded mode wherein one of said set of receiver channels is designated as a useful channel, and a useful signal is supplied as the decoded mode if it is received on the useful channel an discarded if it is received on the other receiver channels of the set, wherein the useful signal represents said information substantially uncorrupted by noise. The technique is applicable to quantum, classical or mesoscopic environments. The invention also provides a method and system for generating correlated states using a similar filtration technique.

Abstract: An apparatus and method for measuring by the Schlieren technique light beam deviations generated by a sample (EV) includes a source (S) of light beam for illuminating the sample (EV) therewith so as to have a transmitted beam. An imaging means is provided (L2, L3) for forming an image of the sample from the transmitted beam. A filtering means acts as a Schlieren filter (SF) for obtaining “Schlieren fringes” from the image. The Schlieren filter (SF) comprises a periodic structure (SFP) of a defined period. A detecting means (CCD) is provided for detecting the Schlieren fringes under operating conditions.

Abstract: Method of conditionally controlling the survivability of a recombinant cell population and of containing such cells to an environment or containing replicons to a host cell is based on the use of proteic killer systems including the E. coli relBE locus and similar systems found in Gram-negative and Gram-positive bacteria and Archae. Such system are generally based on a cytotoxin polypeptide and an antitoxin or antidote polypeptide that in contrast to the cytotoxin is degradable by proteases. The recombinant cells are useful as vaccines, pollulant degrading organisms or as biogical pest control organisms e.g. expressing B. thuringiensis crystalline proteins.

Abstract: A cloning and/or sequencing vector enables recombinant clones to be selected directly. The vector encodes a fusion protein which includes a protein poison.

Abstract: The present invention is related to a mutated E7 polypeptide obtained from the human Papillomavirus HPV-16 as well as the pharmaceutical composition comprising it and its preparation process.