Patents Assigned to Universität
  • FELINE LEUKEMIA VIRUS TRANS-MEMBRANE PROTEIN P15E FOR DIAGNOSIS OF FELV INFECTION
    Publication number: 20140141410
    Abstract: The invention provides for a method for the detection of FeLV infection in a patient, wherein a sample obtained from the patient is contacted in-vitro with a recombinant transmembrane p15E protein in a p15 (E) antibody binding step.
    Type: Application
    Filed: July 6, 2012
    Publication date: May 22, 2014
    Applicant: UNIVERSITAT ZURICH
    Inventors: Hans Lutz, Eva Bonzli, Regina Hofmann-Lehmann
  • Antibodies against prostate-specific stem cell antigen and use thereof
    Publication number: 20140134155
    Abstract: The invention relates to recombinant antibodies which bind to prostate-specific stem cell antigen (PSCA). The antibody of the invention comprises complementarity-determining regions (CDR) having the following amino acid sequences: CDR of the variable region of the light chain: CDR1 SEQ ID No. 1, CDR2 SEQ ID No. 2, CDR3 SEQ ID No. 3, and CDR of the variable region of the heavy chain: CDR1 SEQ ID No. 4, CDR2 SEQ ID No. 5, CDR3 SEQ ID No. 6. The invention also embraces the use of the antibodies of the invention as medicinal products, especially for the treatment of tumour diseases, or as a diagnostic agent. The antibodies are suitable for use in the areas of medicine, pharmacy and biomedical research.
    Type: Application
    Filed: June 29, 2012
    Publication date: May 15, 2014
    Applicant: Technische Universität Dresden
    Inventor: Michael Bachmann
  • MAGNETOSTRICTIVE LAYER SYSTEM
    Publication number: 20140125332
    Abstract: A magnetostrictive layer system is suggested comprising at least one layer sequence comprising an anti-ferromagnetic, (AFM), layer and a magnetostrictive, ferromagnetic, FM, layer arranged directly thereon, wherein the layer sequence has an associated exchange bias, EB, field, the EB-induced degree of magnetization of the FM layer in the absence of an external magnetic field being within a range between 85% and 100%, and the angle ?opt, which is enclosed by the EB field direction and the magnetostriction direction, that has the maximum piezomagnetic coefficient in the absence of an external magnetic field, within a plane parallel to the AFM layer and the FM layer lies within a range between 10° and 80°.
    Type: Application
    Filed: June 20, 2012
    Publication date: May 8, 2014
    Applicant: CHRISTIAN-ALBRECHTS-UNIVERSITÄT ZU KIEL
    Inventors: Enno Lage, Dirk Meyners, Eckhard Quandt
  • ANTIBODIES FOR TREATMENT OF CANCER
    Publication number: 20140127219
    Abstract: The present invention provides antibodies useful as therapeutics for treating and/or preventing diseases associated with cells expressing CLDN6, including tumor-related diseases such as ovarian cancer, lung cancer, gastric cancer, breast cancer, hepatic cancer, pancreatic cancer, skin cancer, malignant melanoma, head and neck cancer, sarcoma, bile duct cancer, cancer of the urinary bladder, kidney cancer, colon cancer, placental choriocarcinoma, cervical cancer, testicular cancer, and uterine cancer.
    Type: Application
    Filed: April 20, 2012
    Publication date: May 8, 2014
    Applicants: JOHANNES GUTENBERG-UNIVERSITÄT MAINZ, GANYMED PHARMACEUTICALS AG
    Inventors: Ugur Sahin, Ozlem Tureci, Michael Koslowski, Korden Walter, Stefan Wöll, Maria Kreuzberg, Bernd Hubner, Michael Erdeljan, Michael Weichel
  • Means for the inhibition of anti-?1-adrenergic receptor antibodies
    Patent number: 8716030
    Abstract: Embodiments of the present invention provide for novel peptides of use for detection and/or inhibition of anti-?1-adrenergic receptor antibodies. Certain embodiments concern uses of cyclic and/or linear peptides. In other embodiments, the present invention relates to novel peptides of use in diagnostic and/or pharmaceutical compositions. Some embodiments concern diagnosing and/or treating cardiac conditions. Cardiac conditions of the instant invention can concern infectious heart disease, non-infectious heart disease, ischemic heart disease, non-ischemic heart disease, inflammatory heart disease, myocarditis, cardiac dilatation, idiopathic cardiomyopathy, idiopathic dilated cardiomyopathy, immune-cardiomyopathy, heart failure, and any cardiac arrhythmia condition.
    Type: Grant
    Filed: April 18, 2012
    Date of Patent: May 6, 2014
    Assignee: Julius-Maximillians-Universitat Wurzburg, A Germany University
    Inventors: Roland Jahns, Valérie Jahns, Martin J. Lohse, Dieter Palm
  • Method for calculating measures of similarity between time signals
    Patent number: 8718803
    Abstract: A method for calculating measures of similarity between time signals, which includes: acquiring and comparing data (xi, yj) of time signals (X, Y); assigning a one or a zero to every two compared data (xi, yj), depending on the result of said comparison, creating a data set; determining time sequences with said ones and zeros of the data set, each one being formed by consecutive sub-sequences of ones, separated by discontinuities of zeros; selecting the highest result of accumulated results obtained for each sub-sequence, adding for each determined point i, j of value one said one to the accumulated result of maximum value, from among the accumulated results at a point i?1, j?1 of said sub-sequence, a point i?2, j?1 of a sub-sequence of a second time sequence, and a point i?1, j?2 of a sub-sequence of a third sequence.
    Type: Grant
    Filed: April 21, 2010
    Date of Patent: May 6, 2014
    Assignee: Universitat Pompeu Fabra
    Inventor: Joan Serra Julià
  • Pyrazole synthesis by coupling of carboxylic acid derivatives and enamines
    Patent number: 8716485
    Abstract: The invention describes a novel process for synthesizing pyrazoles by means of oxidative conversion of enamines with suitable N-containing carboxylic acid derivatives.
    Type: Grant
    Filed: March 23, 2011
    Date of Patent: May 6, 2014
    Assignee: Westfälishe Wilhelms-Universität Münster
    Inventors: Julia Neumann, Mamta Suri, Frank Glorius
  • Means for the inhibition of anti-beta1-adrenergic receptor antibodies
    Patent number: 8715682
    Abstract: Embodiments of the present invention provide for novel peptides of use for detection and/or inhibition of anti-?1-adrenergic receptor antibodies. Certain embodiments concern uses of cyclic and/or linear peptides. In other embodiments, the present invention relates to novel peptides of use in diagnostic and/or pharmaceutical compositions. Some embodiments concern diagnosing and/or treating cardiac conditions. Cardiac conditions of the instant invention can concern infectious heart disease, non-infectious heart disease, ischemic heart disease, non-ischemic heart disease, inflammatory heart disease, myocarditis, cardiac dilatation, idiopathic cardiomyopathy, idiopathic dilated cardiomyopathy, immune-cardiomyopathy, heart failure, and any cardiac arrhythmia condition.
    Type: Grant
    Filed: April 18, 2012
    Date of Patent: May 6, 2014
    Assignee: Julius-Mazimillians-Universitat Wurzburg, a German University
    Inventors: Roland Jahns, Valérie Jahns, Martin J. Lohse, Dieter Palm
  • MICRORNA (miRNA) AND DOWNSTREAM TARGETS FOR DIAGNOSTIC AND THERAPEUTIC PURPOSES
    Publication number: 20140121264
    Abstract: In some embodiments, the invention is directed to a method for diagnosing fibrosis and/or fibrosis related diseases and to a method for screening a pharmaceutically active compound for the treatment of fibrosis and/or fibrosis related diseases. The present invention further relates to compositions for use in the treatment, amelioration, and/or prevention of fibrosis. In certain embodiments, the compositions modulate the activity of a miRNA for the treatment, amelioration, and/or prevention of fibrosis. In certain embodiments, the compositions inhibit the activity of miR-21 for the treatment, amelioration, and/or prevention of fibrosis.
    Type: Application
    Filed: October 23, 2013
    Publication date: May 1, 2014
    Applicant: JULIUS-MAXIMILIANS-UNIVERSITAT WURZBURG
    Inventors: Thomas Thum, Johann Bauersachs, Stefan Engelhardt, Carina Gross
  • Apparatus and Method for Evaluating Characteristics of Target Molecules
    Publication number: 20140116892
    Abstract: Arrangements are described for evaluating characteristics of target molecules. A biochip is received which includes a substrate to which charged probe molecules are attached. The probe molecules have a marker to allow generating signals indicative of the distance of a portion of the probe molecule from the substrate. The signals are detected and means for an external electric field is generated to which the probe molecules are exposed. A control means acts to: (A) apply an external electric field causing the portion of the probe molecule to approach the substrate, and (B) apply an external electric field causing the portion of the probe molecule to move away from the substrate. The signal is recorded as a function of time during step (A) and/or step (B). Steps (A) and (B) are repeated for a predetermined number of times and the recorded signals are combined.
    Type: Application
    Filed: March 26, 2013
    Publication date: May 1, 2014
    Applicant: TECHNISCHE UNIVERSITÄT MÜNCHEN
    Inventor: TECHNISCHE UNIVERSITÄT MÜNCHEN
  • TREATMENT FOR MUSCULAR DYSTROPHIES
    Publication number: 20140121171
    Abstract: miRNA-21 inhibitors and pharmaceutical compositions including an miRNA-21 inhibitor together with pharmaceutical excipients and carriers for use in the treatment of a muscular dystrophy and/or a muscular dystrophy-like myopathy. Particularly, the miRNA-21 inhibitors and pharmaceutical compositions including the same are for use in the regeneration of skeletal muscle in muscular dystrophy and/or a muscular dystrophy-like myopathy patients.
    Type: Application
    Filed: June 14, 2012
    Publication date: May 1, 2014
    Applicants: INSTITUCIÓ CATALANA DE RECERCA I ESTUDIS AVANÇATS, UNIVERSITAT POMPEU FABRA
    Inventors: Purificación Muñoz-Cánoves, Marina Raya Chamorro, Eusebio Perdiguero Santamaría, Antonio Luis Serrano
  • polypeptide, DNA encoding the polypeptide and a vaccine comprising the polypeptide
    Patent number: 8709437
    Abstract: The present invention pertains to the identification and initial characterization of CctA, a novel, secreted toxin of Clostridium chauvoei that represents the major cytotoxic activity of C. chauvoei. This toxin confers C. chauvoei its characteristic strong hemolytic activity towards erythrocytes of various species, since anti-CctA antibodies fully neutralize hemolysis by C. chauvoei on standard blood-agar medium or in cell-free supernatants of liquid cultures.
    Type: Grant
    Filed: January 28, 2010
    Date of Patent: April 29, 2014
    Assignees: Intervet International B.V., Universitat Bern
    Inventors: Keith Redhead, Joachim Frey, Edy M. Vilei, Andreas Walter Claudius Rohwer, Anders Johansson
  • Bio-pesticide and method for pest control
    Patent number: 8709399
    Abstract: The present invention relates to a new method for pest control and/or for preventing or treating pest infestation. Said method comprises the inoculation of plants, parts of plants or the surrounding of said plants with an effective amount of endophytic Beauveria bassiana strains. In a further aspect the present invention relates to the use of an isolated Beauveria bassiana strain having superior properties. Furthermore, biopesticides and compositions for pest control, in particular, for control of herbivorous insects and/or plant pathogens, are provided.
    Type: Grant
    Filed: March 24, 2011
    Date of Patent: April 29, 2014
    Assignee: Georg-August-Universität Göttingen Stiftung Öffentlichen Rechts
    Inventors: Stefan Vidal, Tadele Tefera
  • Molecular hydrogen stores and hydrogen transfer reagents for hydrogenation reactions
    Patent number: 8709377
    Abstract: The present invention relates to a process for reversible hydrogen storage, to a material for reversible hydrogen storage and to the use of the material for reversible hydrogen storage.
    Type: Grant
    Filed: April 15, 2008
    Date of Patent: April 29, 2014
    Assignee: Universitat Heidelberg
    Inventors: Hans-Jörg Himmel, Elisabeth Kaifer, Oxana Ciobanu, Pascal Roquette, Walter Siebert
  • USE OF AN AGENT CONSISTING OF ANTIBODIES AND/OR INSULIN-LIKE GROWTH FACTOR ANTAGONISTS
    Publication number: 20140112937
    Abstract: The present invention relates to the use of a composition selected from the group consisting of antibodies, antibody fragments, insulin-like growth factor antagonists, Toll-like receptor antagonists and mixtures thereof for the treatment or the prophylaxis of certain diseases.
    Type: Application
    Filed: March 28, 2012
    Publication date: April 24, 2014
    Applicants: FREISTAAT BAYERN REPRESENTED BY JULIUS- -MAXIMILIANS-UNIVERSITAT WURZBURG, MAT-MALTA ADVANCED TECHNOLOGIES LIMITED
    Inventors: Jan Wesjohann, Günter Sprotte, Ana Maria
  • Audio signal transforming by utilizing a computational cost function
    Patent number: 8706496
    Abstract: A sequence is received of time domain digital audio samples representing sound (e.g., a sound generated by a human voice or a musical instrument). The time domain digital audio samples are processed to derive a corresponding sequence of audio pulses in the time domain. Each of the audio pulses is associated with a characteristic frequency. Frequency domain information is derived about each of at least some of the audio pulses. The sound represented by the time domain digital audio samples is transformed by processing the audio pulses using the frequency domain information. The sound transformation utilizes overlapping windows and a computational cost function which depends on a product of the number of the pitch periods and the inverse of the minimum fundamental frequency within the window is determined.
    Type: Grant
    Filed: September 13, 2007
    Date of Patent: April 22, 2014
    Assignee: Universitat Pompeu Fabra
    Inventor: Jordi Bonada Sanjaume
  • Method for determining centers of mass for large structures
    Patent number: 8701472
    Abstract: The spatial center of mass and a mass of an object can be determined by orientating the suspended object in at least two different spatial positions and measuring the orientation of the object in each of the different spatial positions the forces acting on the suspension devices because of the suspended object, the forces acting on the suspension devices being resolved into three independent force components. A center of area of the object and the associated force effect lines are determined for each of the at least two spatial positions, the center of area of the respective spatial position being determined with an inclined tension compensation of the suspension devices. The spatial center of mass is determined by superimposing at least two force effect lines.
    Type: Grant
    Filed: April 9, 2008
    Date of Patent: April 22, 2014
    Assignees: Fraunhofer-Gesellschaft zur Foerderung der angewandten Forschung e.V., Universität Rostock
    Inventors: Oliver Wurst, Martin-Christoph Wanner, Birger Schubert
  • Microstructured composite component and method and device for producing the same
    Patent number: 8703039
    Abstract: A microstructured composite component is provided including structures for carrying out fluid processes. A device is provided for producing microstructured composite components. A method provided includes a first step during which a first film is arranged above a second film between first and second mold parts. The first and/or second mold parts have microstructured cavities to be filled. In a second step, the first and second mold parts are heated in at least one region in which they contact one of the films. An excess pressure is then produced between the first film and the second film to force the first and/or second films into the cavities. In a further step, the first and second mold parts are pressed together by a pressing force. Once the first mold part, the second mold part, the first film and the second film are cooled, they form a microstrutured composite component.
    Type: Grant
    Filed: February 24, 2010
    Date of Patent: April 22, 2014
    Assignee: Technische Universitat Ilmenau
    Inventors: Andreas Schober, Alexander Gross, Joerg Hampl
  • Thermoplastic paste for repairing living tissues
    Patent number: 8703111
    Abstract: This invention relates to a thermoplastic paste with a highly thixotropic rheology, the components of which are a block biopolymer and a bioceramic. The material described herein can be used in bone implants and in the regeneration of both animal and plant live tissues.
    Type: Grant
    Filed: May 6, 2009
    Date of Patent: April 22, 2014
    Assignees: Institut Quimic de Sarria Cets, Fundacio Privada, Universitat Ramon Llull, Fundacio Privada
    Inventors: Salvador Borros Gómez, David Horna Tomás
  • Immunological Test for Detecting Autoantibodies Against Testicular Antigens
    Publication number: 20140106379
    Abstract: The present invention discloses an immunological test for the detection and specific determination of autoantibodies against testicular antigens which are associated with inflammation-related fertility disorders of male mammals in a biological sample of a male mammal, in particular the detection of testicular ER-60 autoantibodies and/or transferrin autoantibodies. The immunological test is utilized to detect the presence of immunologically-caused and infection-related infertility in male mammals, particularly in humans.
    Type: Application
    Filed: September 9, 2013
    Publication date: April 17, 2014
    Applicant: JUSTUS-LIEBIG-UNIVERSITAT GIESSEN
    Inventors: ANDREAS MEINHARDT, MONIKA FIJAK