Abstract: The present invention is directed to Nogo-A antagonists useful for the control of blood glucose or blood insulin levels in a subject and related use and formulation thereof. In particular, the invention is directed to Nogo-A antagonists useful for the prevention, repression or treatment insulin secretion deficiency and related methods and pharmaceutical formulations. In particular, the invention relates to Nogo-A antagonists useful in the treatment of diabetes mellitus.

Abstract: Methods and systems to decentralize managing of neighboring femtocells. The methods and systems include communication to a first femtocell from a second femtocell of next information that includes communicated information of: i) the interference requirement constraint of an active user of the second femtocell, and ii) one or more parameters characterizing a physical radio channel defined from the first femtocell to the at least one active user of the second femtocell; the self-configuration of the transmission parameters of the first femtocell based upon the communicated information i) and ii). Another method (and system to implement the method) includes the mutual adjustment of the interference requirement constraints between a first and a second femtocell, regarding their active users, in a decentralized manner, on the basis of not affecting the transmission performance of the rest of the plurality of femtocells.

Abstract: Mix which comprises a) one or more very finely divided silicon dioxide powders having an average particle diameter of from 2 to 100 nm and a BET surface area of at least 30 m2/g, b) one or more particulate components selected from the group consisting of oxides, carbides and nitrides, in each case having an average particle diameter of from >0.5 ?m to 30 mm, c) one or more synthetic resins as binders and d) one or more metallic antioxidants having an average particle diameter of from >0.5 to 250 ?m. Process for producing a shaped body, in which to the mix is introduced into a mould, pressed if appropriate and heated to a temperature at which the synthetic resin crosslinks thermally. Shaped body which can be obtained therefrom. Process for producing a refractory shaped body, in which the shaped body is carbonized. Refractory shaped body which can be obtained therefrom.

Abstract: The invention relates to a parametric oscillator (1) for generating ultra-short pulses. The system (1) comprises a resonator (10) having an optical axis (11), an amplifier crystal (9) arranged in the resonator (10), and a pump laser system (4) for generating pump laser radiation (5) comprising pump photons, said pump laser radiation being directed onto the amplifier crystal (9). The invention is characterized in that the amplifier crystal (9) is an optically non-linear crystal configured for generating a signal photon and an idler photon from a pump photon by means of an optical-parametric process, wherein the resonator (10) is arranged in such a way that a signal pulse formed from the signal photons leaves the amplifier crystal (9) along the optical axis (11) of the resonator (10), and wherein dispersion compensation members for at least partially compensating the dispersion of the radiation circulating in the resonator (10) are provided.

Abstract: A method for analysis of analytes in a sample and to the use of such a method and a method for monitoring progress, or treatment of a disease such as fat-related disease. These analysis methods include the steps of providing the sample, measuring of values of analytes in the sample, calculating of values based on the measured values, identifying and optionally visualizing analytes can particularly be used for monitoring quantitative changes of analytes and for monitoring progress or treatment of a disease such as a fat-related disease.

Abstract: The present invention, among others, relates to a compound having a structure according to formula (I) or a pharmaceutically acceptable salt thereof, wherein Xaa1 to Xaa4 are independently of each other, an optionally N-alkylated natural or unnatural amino acid, R is H or methyl, L is a linker moiety, Ar is a spacer comprising an aromatic moiety, and D comprises, preferably is i) a combination of an organic complexation agent and a detectable label; or ii) a detectable label, an organic complexation agent or an active substance, said active substance particularly being selected from cytotoxic agents, lipids, sugars, sugar conjugates, sugar derivatives, proteins and combinations thereof, with the proviso that -L-Ar-D does not comprise a 18F-benzoyl residue.

Abstract: The present invention relates to a compound of formula (I) wherein R1, R2 and R3 are as defined in the description and the physiologically acceptable salts thereof as well as the physiologically acceptable solvates of the compounds of formula I and of the salts thereof. The compounds of formula I are suitable for treating tumors.

Abstract: 6-(alkylbenzylamino)purine derivatives of the general formula I for use as cytokinin receptor antagonists. R1 is selected from a group which includes, but is not limited to, hydroxyl, amino, nitro, thio and alkyl group. R2 denotes one to four alkyl groups. The invention also relates to preparations containing these derivatives and methods of using the derivatives.

Abstract: The invention relates to transparent rectifying contact structures for application in electronic devices, in particular appertaining to optoelectronics, solar technology and sensor technology, and also a method for the production thereof. The transparent rectifying contact structure according to the invention has the following constituents: a) a transparent semiconductor, b) a transparent, non-insulating and non-conducting layer composed of metal oxide, metal sulphide and/or metal nitride, the resistivity of which is preferably in the range of 102 ?cm to 107 ?cm and c) a layer composed of a transparent electrical conductor wherein the layer b) is formed between the semiconductor a) and the layer c) and the composition of the layer b) is defined in greater detail in the description of the patent.

Abstract: A medical device is disclosed, which comprises a functional unit (C) for permanent or temporary placement in the urogenital tract of a human or animal body. The functional unit has at least one electrically conducting portion. A power source (G) supplies a current to the electrically conducting portion after placement of the functional unit in the urogenital tract. In this manner, the growth of bacteria on the functional unit can be reduced.

Abstract: The invention relates to a valve device for controlling a flow of a fluid through a fluid channel, having a tube (2) made of a flexible material, in which a section of a fluid channel is formed, a valve component (1) assigned to the tube (2), a cantilevered arm (8), which is designed to be reversibly displaceable on the valve component (1) against a restoring force supplied at least partially by the cantilevered arm (8) itself, a squeeze element (10), which is arranged on a distal end of the cantilevered arm (8) for support of the cantilevered arm (8) on the valve component (1) and is configured to control a flow of a fluid through the fluid channel by pressing against an outside surface of the tube (2), optionally up to the closing of the fluid channel, and an actuator (11) which is configured to displace the squeeze element (10) in various control directions against the restoring force on the cantilevered arm (8), so that the pressure of the squeeze element (10) on the outside surface of the tube (2) and th

Abstract: The present invention relates to a balloon catheter system for draining and/or supplying fluid from/into hollow organs, body cavities or cysts, comprising a conduit catheter with an open distal end, a hollow needle guided in a separate guide conduit and a balloon surrounding the catheter stem at the distal end of the conduit catheter. The conduit catheter with the hollow needle can be inserted from outside into the hollow organ via a guide catheter, into the body cavity or cyst, the balloon can be filled with filling medium via the hollow needle through an opening formed in the guided duct and provided in the lumen of the balloon, and it can be fixed in the hollow organ, body cavity or cyst. The hollow needle can be removed from the guide duct after filling the balloon. The balloon and the conduit catheter remain in the hollow organ, body cavity or cyst.

Abstract: The invention relates to growth-inhibited hydroxyapatite for improving bone healing. It differs from the apatites employed to date in that it releases calcium ions and phosphate ions in physiological solutions, which, unlike traditional hydroxyapatites, it does not bind. It thereby promotes bone regeneration and bone growth. The growth-inhibited hydroxyapatite contains in agglomerates of prestructured collagen templates on which hydroxyapatite crystals with a crystallite growth of below its critical nucleus radius are formed epitactically. It is prepared by the steps a) mineralization of prestructured collagen templates in supersaturated Ca- and phosphate-ion-containing solutions, where the prestructured collagen templates are capable of diffusion and/or migration, so that HAP crystallites grow epitactically on the collagen templates and the collagen templates grown together with HAP crystallites agglomerate due to their capability of diffusion and/or migration, b) separating off the agglomerates.

Abstract: The present invention relates to vinylogous chalcone derivatives, in particular the compounds of formula (I) as described and defined herein, pharmaceutical compositions comprising these compounds, and their medical use, including their use in the treatment or prevention of cancer, in particular malignant hematological diseases/disorders.

Abstract: The present invention relates to a bioprocess for recycling waste paper originated from high quality paper comprising the following steps: a) preparation of pulp; b) dilution with water of the pulped material obtained in a) c) enzymatic treatment of pulp; d) addition of inorganic salts and glues; e) dilution with water of the material obtained in d) f) filtration by vacuum; optional press; and g) drying In particular, said high quality paper is printed paper. The present invention also relates to the obtainable product by the above mentioned process. The present invention further relates to the different uses of the product such as building and construction material, eco-packaging material and eco-decorative material.

Abstract: The invention relates to a method of authentication and session key agreement for secure data transmission between a first and second data communication entity in an electronic data transmission system. Furthermore, the invention relates to an electronic transmission system to perform a method of authentication and session key agreement.

Abstract: The present invention concerns an (adjuvant) treatment or prevention option for the treatment and prevention of prostate cancer. In particular, it pertains to the provision of recombinant, optimized PAP genes which are useful as DNA vaccines for the above treatment or prevention.

Abstract: The present invention relates to antagonists of the expression and/or the function of the micro RNA miRNA-29 for use in the prevention and/or treatment of aortic aneurysms. Further disclosed is a method for the identification of miRNA-29 antagonists, a pharmaceutical composition comprising said miRNA-29 antagonists and a method for preventing and treating age-related aortic aneurysm formation in a subject in need of such a treatment.

Abstract: Method for compensating illumination deficiencies in microscopic “shape from focus (SFF)”, wherein firstly the reflectance of the scene is estimated by way of a projector-camera system and then microscopic “shape from focus (SFF)” is applied to a stack of reflectance maps rather than to the original image data.

Abstract: The invention relates to a gas sensor for detecting gas in the air, especially formaldehyde. The sensor comprises at least one gas-sensitive zone which is preferably a layer on a substrate and which contains the ternary compound In4Sn3O12 as the gas-sensitive material. In order to produce the gas-sensitive zone, a flame spray pyrolysis (FSP) is carried out, organometallic compounds of indium and tin being used as the reactants. The gas sensor is especially suitable for online gas detection.