Abstract: The present invention relates to a method and an apparatus for establishing residual stresses in objects, in particular in coated objects, and to a method and an apparatus for coating objects. The method comprises: impinging a surface (8) of the object (5) with laser light and generating a hole or a pattern of holes and/or locally heated points in the object (5); establishing the surface deformations by an optical deforming measuring method after the object (5) is impinged by laser light; establishing the residual stresses present in the object (5) from the measured surface deformations, wherein the generation of the hole pattern is carried out by an optical scanning apparatus which comprises an optical deflection and/or modulation arrangement for controllable deflection and/or modulation of the laser light, and/or a focusing arrangement for controllable focusing of the laser light.

Abstract: The present invention relates to a polypeptide comprising a component A with at least three tumor necrosis factor (TNF) homology domains of TNF-ligand family members (THD) in which C-terminal and N-terminal reference points are defined by consensus sequences and which are connected through short stretches of additional C-terminal and/or N-terminal amino acids of the THD or variants thereof, and a component B comprising a dimerization domain. Further, the present invention relates to a polypeptide comprising at least three THDs in which C-terminal and N-terminal reference points are defined by consensus sequences and which are connected through short stretches of additional C-terminal and/or N-terminal amino acids of the THD or variants thereof. Further, the invention relates to a nucleic acid comprising said polypeptides, a vector comprising said nucleic acid and a pharmaceutical composition comprising said polypeptides, or said nucleic acids or said vector.

Abstract: The present invention relates to complexes comprising (i) an immunoglobulin (Ig) binding moiety and (ii) a pharmaceutically active moiety, wherein the Ig binding moiety specifically binds to the constant domain 1 of the heavy chain (CH1) of an Ig molecule and their use for therapy and prophylaxis.

Abstract: The present invention relates to a method and a computer program product for generating a high-resolution three-dimensional (3D) voxel data set of an object. The high-resolution three-dimensional (3D) voxel data set is generated with the aid of a computed tomography scanner. In some aspects of the present disclosure a 3D image data set is generated by acquiring computed tomography images of the object. In other aspects of the present disclosure the 3D voxel data set of the object is generated with the aid of an image data reconstruction algorithm.

Abstract: The present invention relates to cytokine fusion proteins and to nucleic acid molecules encoding such cytokine fusion proteins. The present invention further relates to cells, non-human organisms. pharmaceutical compositions and kits comprising the cytokine fusion proteins or the nucleic acid molecules encoding them, as well as to their use as medicaments.

Abstract: The present invention relates to a method and a computer program product for generating an artifact-reduced voxel data record of an object. The artifact-reduced voxel data record of the object is generated with the aid of a computed tomography scanner. In some aspects of the present disclosure, a first image data record and a second image data record is generated by acquiring computed tomography images of the object. In still other aspects of the present disclosure, the artifact-reduced voxel data record of the object is generated with the aid of an image data reconstruction algorithm.

Abstract: The present invention provides a flexible high-density fiberboard which is essentially free of formaldehyde and isocyanates and comprises 70 to 90% by weight of straw fibers, and 30 to 10% by weight of a thermoplastic elastomer and one or more optional additive(s). Furthermore, the present invention provides a method for manufacturing such a flexible high-density fiberboard comprising the steps of providing straw fibers, providing a thermoplastic elastomer in powder form, optionally providing one or more additive(s), dry mixing the straw fibers, the thermoplastic elastomer powder and optionally the one or more additive(s), such that a mixture comprising 70 to 90% by weight of the straw fibers, and 30 to 10% by weight of the thermoplastic elastomer and one or more of the optional additive(s) is obtained, extruding the obtained mixture at a temperature such that the thermoplastic elastomer powder is in a molten state, and pressing the extruded mixture.

Abstract: In a method for impregnating semi-finished fibrous products using resin as the impregnating means, winding or laying the semi-finished fibrous products in a plurality of layers on top of one another onto a receiving carrier is initially performed. Here, lower layers lie close to the receiving carrier, and upper layers lie more remote therefrom. The receiving carrier is configured so as to be permeable to the impregnating means. The impregnating means is then introduced through the receiving carrier into the semi-finished fibrous products, wherein the impregnating means initially permeates the lower layers and then permeates the upper layers of the semi-finished fibrous products.

Abstract: The invention relates to an N-heterocyclic carbene complex of general formulas I to IV (I) (II) (III) (IV), according to which A1 stands for NR2 or PR2, A2 stands for CR2 R2?, NR2, PR2, 0 or S, A3 stands for N or P, and C stands for a carbene carbon atom, ring B is an unsubstituted or a mono or poly-substituted 5 to 7-membered ring, substituents R2 and R2? stand, inter alia, for a linear or branched C1-Cw-alkyl group and, if N and N each stand for NR2 or PR2, are the same or different, M in formulas I, II, III or IV stands for Cr, Mo or W, X 1 or X2 in formulas I to IV are the same or different and represent, inter alia, C1-C1s carboxylates and C1-C1s-alkoxides, Y is inter alia oxygen or sulphur, Z is inter alia a linear or branched C1-Cw-alkylenoxy group, and R 1 and R1? in formulas I to IV are, inter alia, an aliphatic or aromatic group.

Abstract: The invention relates to methods and to devices for generating multispectral illuminating light having an addressable spectrum, for adaptive multispectral imaging and for capturing structural and/or topographical information of an object or of the distance to an object. The illuminating device comprises a multispectral light source and a modulator for temporal modulation of the individual spectral components of the multispectral light source having modulation frequencies. The multispectral light source comprises at least one light source having a continuous, quasi-continuous, or frequency comb spectrum and wavelength-dispersive means, or an assembly or array of monochromatic or quasi-monochromatic light sources having emission wavelengths or emission wavelength bands which are different from one another in each case.

Abstract: The invention relates to a method for compressing an input data set, which comprises one or more input values, comprising the following steps: determining, for each input value, a tolerance range; generating encoded lossy values by a lossy encoding of the input values; generating output values associated with the input values, in particular by decoding the encoded lossy values; generating difference values by subtracting each decoded lossy value from the respectively associated input value; comparing each difference value with the respectively associated determined tolerance range; generating encoded correction values associated with the encoded lossy values on the basis of the difference values, wherein the encoded correction values are offset values, which can be added to the associated encoded lossy values; and providing an output data record as a function of a comparison of the difference values with the tolerance ranges and on the basis of the encoded lossy values and/or the encoded correction values.

Abstract: The present invention relates to a method and an apparatus for establishing residual stresses in objects, in particular in coated objects, and to a method and an apparatus for coating objects. The method comprises: impinging a surface (8) of the object (5) with laser light and generating a hole or a pattern of holes and/or locally heated points in the object (5); establishing the surface deformations by an optical deforming measuring method after the object (5) is impinged by laser light; establishing the residual stresses present in the object (5) from the measured surface deformations, wherein the generation of the hole pattern is carried out by an optical scanning apparatus which comprises an optical deflection and/or modulation arrangement for controllable deflection and/or modulation of the laser light, and/or a focusing arrangement for controllable focusing of the laser light.

Abstract: The present invention relates in general to the field of TNF ligand family members. In more detail the present invention relates to polypeptides comprising at least three components A, each of which comprises the sequence of a TNF homology domain (THD) of a TNF ligand family member, or a functional derivative thereof, and comprising at least one component B consisting of a VL region and a VH region linked directly to each other with a linker sequence L which has a length of <12 amino acids. Furthermore, the present invention also relates to nucleic acids encoding such polypeptides and pharmaceutical compositions thereof.

Abstract: The present invention provides a polypeptides comprising a heavy chain domain 2 (HD2) from IgM or IgE and at least one pharmaceutically active moiety, complexes thereof and their use for therapy and prophylaxis.

Abstract: The present invention relates to a method for connecting a solid core optical fiber (2) with another optical fiber (20), wherein the solid core optical fiber (2) comprises a joining device (10), which is created on one axial end of the solid core optical fiber (2) using a 3D printer and wherein the other optical fiber (20) is incorporated in the joining device (10) via an axial end of the other optical fiber (20), which is thus connected with the solid core optical fiber (2). In addition, the invention relates to a solid core optical fiber (2) with a joining device (10) created by a 3D-printer, and the relevant use of a 3D printer.

Abstract: Disclosed herein is a measuring probe and an arrangement for measuring spectral absorption, preferably in the infrared. Furthermore, the invention relates to a method for spectroscopically measuring absorption. The measuring probe may comprise a cutting apparatus configured to cut a slice or respectively flap off of a sample to be measured; a measuring gap configured to accommodate the sample slice; an optical window element for coupling measuring light into, or respectively out of the measuring gap; and an end reflector designed and arranged to reflect the measuring light propagated through the measuring gap back into the measuring gap. The arrangement for measuring spectral absorption may comprise the measuring probe, a light source and an apparatus for the spectral analysis of the measuring light coupled out of the measuring gap.

Abstract: Disclosed are methods and an assembly for robust one-shot interferometry, in particular for optical coherence tomography according to the spatial domain approach (SD-OCT) and/or according to the light-field approach. In one embodiment, the method and the assembly may be used for measurements on material and living tissue, for distance measurement, for 2D or 3D measurement with a finely structured light source imaged onto the object in a diffraction-limited way, or with spots thereof. The assembly may comprise an interferometer having object and reference arms and a detector for electromagnetic radiation. In other embodiments, during a detection process, a plurality of spatial interferograms may be formed by making an inclined and/or curved reference wavefront interfere with an object wavefront for each measurement point. The resulting spatial interferograms may be detected in a single detector frame and may be further evaluated via a computer program.

Abstract: The invention relates to an N-heterocyclic carbene complex of general formulas I to IV (I) (II) (III) (IV), according to which A1 stands for NR2 or PR2, A2 stands for CR2 R2?, NR2, PR2, 0 or S, A3 stands for N or P, and C stands for a carbene carbon atom, ring B is an unsubstituted or a mono or poly-substituted 5 to 7-membered ring, substituents R2 and R2? stand, inter alia, for a linear or branched C1-Cw-alkyl group and, if N and N each stand for NR2 or PR2, are the same or different, M in formulas I, II, III or IV stands for Cr, Mo or W, X 1 or X2 in formulas I to IV are the same or different and represent, inter alia, C1-C1s carboxylates and C1-C1s-alkoxides, Y is inter alia oxygen or sulphur, Z is inter alia a linear or branched C1-Cw-alkylenoxy group, and R 1 and R1? in formulas I to IV are, inter alia, an aliphatic or aromatic group.

Abstract: A method for producing a porous nanocrystalline semiconductor layer (100) is provided, including: a) providing a substrate (10) having a substrate surface; b) coating a semiconductor layer (12) on the substrate surface; c) coating a metal containing layer (14) on the semiconductor layer; d) heat treating the semiconductor layer and the metal containing layer at a temperature and for a time period such that the semiconductor and the metal partially interdiffuse and the semiconductor is at least partially crystallized; and e) least partially removing the metal. Further, a porous nanocrystalline semiconductor layer, a use thereof, an anode, and a secondary lithium-ion battery are provided.

Abstract: Disclosed herein is an apparatus for spectroscopic ellipsometry, preferably for infrared spectroscopic ellipsometry, and a method for spectroscopic ellipsometry employing the apparatus. In some embodiments, the apparatus may comprise a light source (12), a detector (30), a polarizer (40), an analyzer (41), and a measuring probe (10). In one embodiment, the measuring probe may comprise an ATR prism (50) having at least one first surface having at least one measuring portion (M) configured to be brought in optical contact with a measured object (72), and at least one second surface having at least one reflective portion (RX).