Abstract: The present application relates to a RNA molecule comprising a RNA-polymerase binding aptamer, wherein said RNA-polymerase binding aptamer has a length of 15 to 60 nt, wherein said RNA-Polymerase binding aptamer binds to a RNA-polymerase with a KD of 50 nM or lower. Furthermore, the application discloses a DNA molecule comprising a sequence encoding an RNA-polymerase binding aptamer of the invention, and a method of producing a protein or RNA of interest comprising providing a vector according to the invention, said vector comprising an expression, introducing said vector into a host cell, and culturing said host cell in culture medium under conditions inducing transcription from the promoter of the expression vector, and optionally recovering the protein of interest from the host cell or culture medium. Furthermore, the application pertains methods for in vitro transcription and expression employing the RNA-polymerase binding apatamers.

Abstract: A spindle arrangement for a machine tool, comprising a spindle for driving a tool and at least one actuator for exciting vibration of the tool, characterized in that the spindle arrangement is provided with a compensation device for at least partly compensating the inertia forces produced by the vibration excitation in the spindle region.

Abstract: Provided are methods for suppressing IgE and IgG-mediated allergic reactions through monoclonal antibody applications. More specifically, methods are herein provided for safe induction of rapid desensitization. Specific embodiments are herein provided for suppressing allergic reactions in a subject, including specific methods of providing a monoclonal antibody selected from the group consisting of anti-Fc?RIa and anti-Fc?RIIb / RIII; administering the antibody to a subject at a dose that is lower than the level required to induce shock; and administering sequentially escalating doses of the monoclonal antibody so as to induce rapid desensitization to an allergen, thereby suppressing allergic reaction in the subject.

Abstract: The invention discloses a method for producing a single bacterial strain culture of Histomonas meleagridis (H. meleagridis), the method being characterized by the following steps: (a) providing a xenic culture of H. meleagridis comprising H. meleagridis cells with a wild type bacterial flora, (b) treating the xenic culture with a mixture of antibiotics thereby killing the wild type bacterial flora, (c) centrifuging and washing the H. meleagridis cells, (d) controlling effectiveness of step (b), (e) resuspending the washed H. meleagridis cells, (f) adding one or more single bacterial strain (s) to the resuspended H. meleagridis cells, and (g) culturing the one or more single bacterial strain (s) with the resuspended H. meleagridis cells so as to obtain a single bacterial strain culture of H. meleagridis.

Abstract: A method and a device for processing a light-polymerizable material (5, 55) for building up an object (27) in layers, using a lithography based generative manufacture having a construction platform (12) for building up the object (27), a projecting exposure unit (10, 60) that can be controlled for locally selected exposing of a surface on the construction platform (12, 62) to an intensity pattern having a prescribed shape, and a control unit (11, 61) prepared for polymerizing overlapping layers (28) on the construction platform (12, 62) in successive exposure steps, each having a prescribed geometry, by controlling the projecting exposure unit (10, 60), in order to thus successively build up the object (27) in the desired shape, said shape resulting from the sequence of layer geometries.

Abstract: A heat storage system using sand as a solid heat storage medium has a fluidized bed heat exchanger (3) arranged between and separated from a storage tank (1) for cold sand and a storage tank (2) for hot sand by weirs (4, 5). The heat exchanger (3) is divided into a plurality of chambers (7) by weirs (6). The weirs (4, 5, 6) are arranged as a combination of overflow and underflow weirs. Fluidized sand is produced in the chambers (7) by a blower (14) positioned underneath the heat exchanger (3). Heat is transferred from a heat source to the sand fluidized and from the fluidized sand to a heat transport medium by transferring mechanisms (8, 9) in the chambers (7). The sand is redirected in a horizontal direction by horizontally acting blowers and/or installations (12) projecting into a respective chamber from a side.

Abstract: The invention relates to a method for the construction of a shaped body from photopolymerizable material by using lithography-based generative production, in which a layer of liquid photopolymerizable material is defined on a production platform, and is polymerized in an exposure region having a predetermined contour, a further layer of photopolymerizable material is defined, the layer defined last is polymerized in an exposure region having a predetermined contour for the layer defined last, and the latter two steps are repeated until a shaped body having a predetermined shape has been formed by the sequence of cured layers with contours predetermined layer by layer, each exposure in an exposure region having a predetermined contour being carried out by controlled activation of individual exposure elements in a two-dimensional array of exposure elements, each exposure element being assigned an image element, wherein the exposure of the exposure region is carried out by a common light source and by a two-dime

Abstract: A device for processing of highly viscous photopolymerizable material for layer-by-layer generation of a shaped body comprises a vat including a bottom which is at least in certain areas thereof transparent, a build platform, an exposure unit for exposing a material layer formed between the lower side of the build platform and the vat bottom in a locally selective manner, a control unit in order to adapt the relative position of the build platform to the vat bottom after each exposure step for a layer, in order to successively build up the shaped body in the desired shape, and a moveably guided doctor blade arrangement including a drive unit for moving the doctor blade arrangement back and forth underneath the build platform. The doctor blade arrangement comprises two doctor blades spaced apart in movement direction, which doctor blades are moveable at a constant distance to the vat bottom along the bottom.

Abstract: The present invention relates to a method for assessing whether a patient suffers from cancer, such as hepatocellular carcinoma, or is prone to suffering from cancer, such as hepatocellular carcinoma, wherein said method comprises determining the amount of soluble AXL in a sample from the patient. The patient is assessed to suffer from cancer or to be prone to suffering from cancer when the amount of soluble AXL is increased in comparison to a control. The present invention relates to the use of soluble AXL for assessing whether a patient suffers from cancer, such as hepatocellular carcinoma, or is prone to suffering from cancer, such as hepatocellular carcinoma. Also a kit for use in the methods of the present invention is provided.

Abstract: The invention relates to a method for producing a tower construction (1) from reinforced concrete. A tower has at least one cavity (35) that extends in the longitudinal direction within the tower. Double-wall elements (2) are arranged along a periphery of the tower, each comprising an external plate (3) as well as an internal plate (4) in vertical or inclined position, forming vertical external joints (5) as well as vertical internal joints (6) between the external plates (3) and the internal plates (4). A reinforcement (9) is installed in the area of the vertical external joints (5) in-between the external plates (3) as well as the vertical internal joints (6) in-between the internal plates (4). The vertical external joints (5) and the vertical internal joints (6) in-between the double-wall elements (2) are closed and the double-wall elements (2) are filled with concrete (23).

Abstract: The invention relates to a method for the construction of a shaped body from photopolymerizable material by using lithography-based generative production (rapid prototyping), in which a layer of liquid photopolymerizable material is defined on a production platform (1, 2, 3, 4), the layer is polymerized in an exposure region having a predetermined contour by exposure, a further layer of photopolymerizable material is defined on the polymerized layer, the layer defined last is polymerized by exposure in an exposure region having a predetermined contour for the layer defined last, and the latter two steps are repeated until a shaped body having a predetermined shape has been formed by the sequence of cured layers with contours predetermined layer by layer, wherein ink is applied onto at least one layer inside the predetermined contour, wherein the production platform is suspended moveably and wherein the production platform is brought, after the polymerization of a layer in a processing station for polymerizing

Abstract: The invention relates to a method and a device (1) for the online-detection of a deterioration in the state of an insulation in an electric machine (2). A stepped voltage is applied to the winding(s) (3) of the machine (2) with the aid of a converter (41), and the current (i) induced in this manner, and/or the time derivative (di/dt) thereof, is acquired as a measurement signal with the aid of at least one sensor (6, 7, 8) and is then oversampled with a frequency higher than the frequencies characteristic for settling. The signal obtained by said oversampling is then evaluated with regard to parameters of the settling process such as overshooting (Ah) and/or natural frequency (1/?T) and/or a damping constant, in order to detect any deterioration in the insulation.

Abstract: Method and systems for locating objects, in particular RFID tags, employ one or more RFID reading devices. The methods and/or systems make it possible to determine a distance between an RFID reading device and a deliberately selected RFID tag in a simple, robust manner. The RFID reading device determines a propagation time of a broadband signal by comparing the broadband signal with the scattered broadband signal. The RFID reading device determines a distance between the RFID reading device and the RFID tag from the propagation time difference.

Abstract: The present invention relates to a pharmaceutical composition comprising a cyclotide for use in immune suppression as well as to a method for immune suppression comprising the step of administering an effective amount of a pharmaceutical composition comprising such a cyclotide to a subject in need thereof. The present invention also relates to a pharmaceutical composition comprising a cyclotide for use in treating or preventing a disorder selected from the group consisting of (i) an autoimmune disorder; (ii) a hypersensitivity disorder; and (iii) a lymphocyte-mediated inflammation. Likewise, the present invention also relates to a method for treating or preventing a disorder selected from the group consisting of (i) an autoimmune disorder; (ii) a hypersensitivity disorder; and (iii) a lymphocyte-mediated inflammation.

Abstract: A method for producing substantially dendritic snow includes: a) supplying a flow of humid air (1) and a flow of cold air (9) into a substantially closed space (15, 16, 17) to mix the two air flows and create an atmosphere oversaturated with water within the space; b) forming ice crystals and allowing snowflakes to grow from the oversaturated atmosphere, keeping the ice crystals and growing snowflakes floating within the space and allowing them to grow over a predetermined period of time sufficiently long to obtain snowflakes having a predefined size, the floating condition being achieved by moving the ice crystals and growing snowflakes, on average, along a substantially helical trajectory by the air flow, which results in the snowflakes being distributed according to their size along the substantially helical trajectory; and c) thereafter releasing the predefined size snowflakes via a release opening (7) of the space by a carrier air flow (3).

Abstract: Disclosed is a vaccine comprising a fiber protein, selected from fiber-2 protein of Fowl Adenovirus C (FAdV-C), fiber-2 protein of Fowl Adenovirus A (FAdV-A), fiber protein of Fowl Adenovirus B, D and E (FAdV-B, FAdV-D and FAdV-E), or an immunogenic fragment thereof for use in preventing hepatitis-hydropericardium Syndrome (HHS) or inclusion body hepatitis (IBH) or Gizzard Erosion (GE) in birds, preferably in poultry, especially in broilers.

Abstract: The invention relates to the use of a composite resin composition comprising (a) at least one polyreactive binder, (b) a first photopolymerization initiator having an absorption maximum at a wavelength of less than 400 nm, (c) a second photopolymerization initiator having an absorption maximum at a wavelength of at least 400 nm and (d) an absorber having an absorption maximum at a wavelength of less than 400 nm, for the stereolithographic production of a dental shaped part based on composite resin. The invention also relates to a process for the stereolithographic production of a dental shaped part and the use of the composite resin composition in this process.

Abstract: Disclosed is a vaccine comprising fiber (2) protein of Fowl Adeno-virus C (FAdV-C) or an immunogenic fragment thereof for use in preventing hepatitis-hydropericardium Syndrome (HHS) in birds, preferably in poultry, especially in broilers.

Abstract: A floating platform is provided including the following: a covering element; at least three buoyant bodies, which are separated from each other, are fixedly mounted to the lower face of the covering element, are open toward the bottom, and are made of a gas-tight, pressure- and corrosion-resistant flexible material. The buoyant bodies enclose a closed hollow space when coming into contact with a liquid surface. At least one compressed-air generating device is also provided for generating an overpressure in the individual hollow spaces.

Abstract: An iron-carbon master alloy is described, with a C content of 0.3 to 8 wt % and an upper limit of alloying metals Ni<10 wt %, P<4 wt %, Cr<5 wt %, preferably<1 wt %, Mn<5 wt %, preferably<1 wt %, Mo<3 wt %, W<3 wt %, Cu<1 wt %, a particle size of >20 ?m and a hardness of <350 HV 0.01, and a method for the manufacture of said master alloy.