Abstract: A method is disclosed for creating an IP right valuation index for an IP portfolio related to an IP right comprising: capturing a quality indicator signal relating to quality indicator data of the IP right; generating a technology field signal relating to a technology field of the IP right; measuring individual IP technology relevance comprising a ratio of the generated technology field signal and the captured quality indicator signal; capturing a total number signal relating to a total number of IP rights in the technology field; determining an IP portfolio signal relating to the number of IP rights within the captured total number signal having ownership of the IP right; measuring IP portfolio strength comprising a ratio of the determined IP portfolio signal and the captured total number signal; and creating an IP right valuation index comprising a product of the individual IP technology relevance and the IP portfolio strength.

Abstract: The present invention refers to a recombinant malaria vaccine and a method for its manufacture.

Abstract: The present invention relates to an isolated nucleic acid molecule, comprising a nucleotide sequence, which encodes a polypeptide with chalcone 3-hydroxylase activity, wherein the nucleotide sequence comprises SEQ ID NO. 1 or has at least a 60% identity with SEQ ID NO. 1 or is able to hybridize with a molecule comprising the sequence of SEQ ID NO. 1, wherein the nucleotide sequence encodes a polypeptide, which comprises the motif FASRPLSX1X2G(X3)m(GSAGGD)n (SEQ ID NO. 3), wherein X1 is threonine or serine, X2 is alanine or glycine, X3 is any amino acid, m is an integer between 50 and 200, and n is 0 or 1.

Abstract: A stimulation system, an implantable electrode device and a method for operating an implantable electrode device are proposed. A simplified implantation, a simple construction and reliable control are made possible by the electrode device being supplied with energy, and controlled, in an exclusively wireless manner via a time-variable magnetic field. The magnetic field is generated by an implanted control device.

Abstract: Device (5) and method or removing suspended-material particles, more particularly fine and ultra-fine particles from a water flow containing suspended-material particles in a pressurised water line (3) of a hydroelectric power plant (2), whereby a tubular element (6) forming a flow channel (7) is provided in the pressurised water line (3), whereby the flow channel (7) essentially extends in the axial direction of the pressurised water line (3), and in the flow channel (7) a stationary swirl-generating device (11) is arranged for stimulating a flow component of the water flow which runs perpendicularly to the main flow direction (9), and in the flow direction after swirl-generating device (11) a separating device (13) is provided for removing the suspended-material particles carried radially outwards due to the effect of centrifugal force.

Abstract: The present invention is concerned with compounds inhibiting CD95 signaling in pancreatic cancer cells. Furthermore, contemplated by the current invention are medicaments comprising such a compound for the prevention and/or treatment of pancreatic cancer as well as the use of such a compound for the manufacture of a medicament for the prevention and/or treatment of pancreatic cancer, the prevention of migration of cancer cells, and/or the prevention and/or treatment of an inflammatory reaction. The present invention also refers to a method for the identification of a compound inhibiting CD95 signaling, as we to a method for the manufacture of a medicament comprising the steps of the method for the identification of a compound inhibiting CD95 signaling and the further step of formulating the inhibiting compound as a medicament.

Abstract: The invention relates to a method of modifying a yeast cell for the production of ethanol. According to the invention, the activity of the Gpd1 protein and/or the Gpd2 protein is reduced.

Abstract: Embodiments of the present invention provide for novel peptides of use for detection and/or inhibition of anti-?1-adrenergic receptor antibodies. Certain embodiments concern uses of cyclic and/or linear peptides. In other embodiments, the present invention relates to novel peptides of use in diagnostic and/or pharmaceutical compositions. Some embodiments concern diagnosing and/or treating cardiac conditions. Cardiac conditions of the instant invention can concern infectious heart disease, non-infectious heart disease, ischemic heart disease, non-ischemic heart disease, inflammatory heart disease, myocarditis, cardiac dilatation, idiopathic cardiomyopathy, idiopathic dilated cardiomyopathy, immune-cardiomyopathy, heart failure, and any cardiac arrhythmia condition.

Abstract: The invention concerns a semiconductor device comprising a structure, wherein the structure comprising a substrate, a first layer onto the substrate comprising GaN and a second layer comprising AlGaN.

Abstract: Embodiments of the present invention provide for novel peptides of use for detection and/or inhibition of anti-?1-adrenergic receptor antibodies. Certain embodiments concern uses of cyclic and/or linear peptides. In other embodiments, the present invention relates to novel peptides of use in diagnostic and/or pharmaceutical compositions. Some embodiments concern diagnosing and/or treating cardiac conditions. Cardiac conditions of the instant invention can concern infectious heart disease, non-infectious heart disease, ischemic heart disease, non-ischemic heart disease, inflammatory heart disease, myocarditis, cardiac dilatation, idiopathic cardiomyopathy, idiopathic dilated cardiomyopathy, immune-cardiomyopathy, heart failure, and any cardiac arrhythmia condition.

Abstract: The present invention relates to the field of diagnostic methods. Specifically, the present invention contemplates a method for diagnosing heart failure in a subject, a method for identifying whether a subject is in need for a therapy of heart failure or a method for determining whether a heart failure therapy is successful. The invention also relates to tools for carrying out the aforementioned methods, such as diagnostic devices.

Abstract: Bioactive molecules are entrapped within a matrix for the controlled delivery of these compounds for therapeutic healing applications. The matrix may be formed of natural or synthetic compounds. The primary method of entrapment of the bioactive molecule is through precipitation of the bioactive molecule during gelation of the matrix, either in vitro or in vivo. The bioactive molecule may be modified to reduce its effective solubility in the matrix to retain it more effectively within the matrix, such as through the deglycosylation of members within the cystine knot growth factor superfamily and particularly within the TGF? superfamily. The matrix may be modified to include sites with binding affinity for different bioactive molecules, for example, for heparin binding.

Abstract: A method for sensing a microwave magnetic field polarization component of a microwave field generated by a microwave device, comprises the steps of generating a static magnetic field having a predetermined amplitude and a predetermined direction relative to the microwave magnetic field polarization component to be sensed, preparing an atom cloud of ultracold probe atoms in defined hyperfine levels, wherein the hyperfine levels of the probe atoms are split in transition frequencies by the static magnetic field, applying a microwave pulse including the microwave magnetic field polarization component to be sensed to the atom cloud, wherein a spatial state distribution of the probe atoms is created by Rabi oscillations during the microwave pulse between the hyperfine levels of the probe atoms being resonant with the microwave magnetic field polarization component, and collecting a state image of the probe atoms, said state image depending on the spatial state distribution of the probe atoms and representing the m

Abstract: The method of the present invention allows obtaining location associated information (3) through the use of a telecommunications device (2) and a two-dimensional code (1) in which the information is stored. The information obtained relates to the geographical position of the two-dimensional code (1), i.e., the location (3), as well as to additional data such as a description thereof, a contact telephone number or its opening hours. The information may be presented according to the language preferences of the user, the two-dimensional code (1) having at least three languages, and it being possible to access a repository with a great number of alternatives or to also translate the content if the repository does not contain the translation in any of the selected languages. The translation will be obtained by accessing the repository with a unique key which includes data relating to the geographical position of the location (3).

Abstract: The present invention establishes a process for creating a set of structures that allows efficient storage and subsequent handling. The multigraph is represented using bitmaps with element counters and mappings between values and organized bitmaps to faciliate the handling of the multigraphs. The bits in the bitmaps represent two aspects of the multigraph: 1) indexing of all the objects of the multigraph as a function of their identifiers and 2) connectivity between objects of the multigraph, whether they are vertices or edges. Mappings allow, given a value, accessing the objects of the multigraph which contain such value. Multigraph operations are solved by accessing the mappings and applying logical operations on the bitmaps. This way of representing a graph allows efficiently performing graph operations such as: inserting a vertex or an edge, inserting an attribute, acquiring the incoming and outgoing edges of an attribute, etc.

Abstract: The present invention relates to the preparation of compounds of the general formula II which can be obtained by 1,4 addition of 2-oxoalkanoates or 2-oxocarboxylic acids onto the appropriate ketones. The present invention also relates to the use of the PigD protein for catalysis of 1,4 additions of 2-oxoalkanoates/-carboxylic acids, for example pyruvate/pyruvic acid or 2-oxobutyrate/2-oxobutyric acid, onto aliphatic, aromatic and heterocyclic ?,?-unsaturated ketones. The 1,4 additions are effected here with CO2 elimination. The use of the PigD protein as a catalyst in the aforementioned 1,4 additions enables the synthesis of addition products with stereoactive centers these addition products being preparable with an enantiomeric excess of more than 80% ee.

Abstract: In a method for manufacturing internally and/or externally profiled rings from pipe material or solid material, machine-cutting processes and forming processes are combined with one another sequentially, parallel, or sequentially and parallel, wherein one of the forming processes is roll forming. During roll forming a counterforce is generated relative to a flow direction of the starting material so that a material flow in at least one of an axial direction and a radial direction of the starting material is controlled such that flowing material is integrated into a profile to be shaped on the ring.

Abstract: The present invention relates to a fixed bed, for example for the isolation and/or purification of components originating from a biological system, which fixed bed comprises magnetic beads and a magnetizable fabric arranged at least in part in the fixed bed, a fluidized bed-fixed bed, which comprises the fixed bed of the invention after application of an alternating magnetic field, and also to a process for the isolation and/or purification of components originating from a biological system.

Abstract: A laying device simultaneous lays at least two substantially parallel and axially spaced apart groups of flexible media lines in at least one flat layer in the soil, wherein each group of flexible media lines has at least one flexible media line. The laying device has a cutting device for generating at least one slot in the ground. The cutting device has one or more substantially vertical blades and a substantially horizontal blade connected to a lower end of the one or more vertical blades, or the cutting device, viewed in the cutting direction, has a round, semi-circular, oval, polygonal or Y-shaped configuration. At least two devices for dispensing the groups of media lines are arranged on the side of the laying device that is facing away from the cutting direction.

Abstract: A receiver including a fiber optic first input element, through which a signal carrying information circulates, a local laser block, a photo-detection block, and a block of differential demodulation is disclosed. The information-carrying signal of the optical fiber input and the beam of light generated by the local laser block provided in the receiver are coupled and detected in a block of optical detection, which converts the optical signal that carries information into an electrical signal that carries information, which is processed in a block of electrical demodulation, which performs a differential demodulation of its in-phase and quadrature components, combining them later. An optical receiver is obtained, featuring optical homodyne detection, being coincident the wavelengths of the input signal and the tuned beam of light, with a high tolerance to the phase noise, generated by the optical communications lasers, and with no need to use an optical phase-locked loop.