Abstract: The process according to the invention for the microbial production of a specific product and methane comprises the following steps: a) the production in a bioreactor (2, 10) of a specific product from a specific substrate using a specific organism, the producer, wherein during the production of this product metabolites such as e.g. low-molecular alcohols, aldehydes and acids, hydrogen and CO2, which may inhibit the production of the product, are obtained; and b) the production of methane by means of a methanogen, wherein in the production of the methane at least one metabolite is decomposed and by this means removed from the bioreactor (2, 10) and its energy is made usable.

Abstract: The invention concerns image data processing, through noise reduction comprising the following steps: associating a learning zone (ZA) with a reference point (Pref) of the image (IM); for each variable point (PC, PC?) of the learning zone, evaluating a distance (d,d?,) between: values of points in a first window (f1) of the image, centered on the reference point, and values of points in a second window (f2, f2,), of similar format as the format of the first window and centered on the variable point; repeating said distance calculation for all the points of the learning zone as successive variable points and estimating an average value to assign to the reference point, said average being weighted on the basis of the distances evaluated for each variable point.

Abstract: The invention relates, inter alia, to an arrangement (10) for generating electromagnetic radiation, wherein the arrangement comprises inorganic semiconductor material and organic material (130), characterized by a semiconductor cylinder (30, 40) composed of inorganic semiconductor material and a charge carrier injection zone (50) situated in the semiconductor cylinder, wherein the charge carrier injection zone adjoins the lateral surface (110) of the semiconductor cylinder, the organic material (130) is suitable for emitting electromagnetic radiation in the case of a charge carrier recombination, and the organic material bears indirectly or directly on that section of the lateral surface of the semiconductor cylinder which is adjoined by the charge carrier injection zone and electron-hole pairs from the charge carrier injection zone of the semiconductor cylinder can enter into the organic material, and excite there the emission of electromagnetic radiation by recombination.

Abstract: The present subject matter can include a two-dimensional electrochemical writing assembly and uses thereof. The writing assembly can enable for time-dependently displaying of a physical parameter, such as a time-dependent display or recording of the temperature. The writing assembly comprises two different types of electrochemical processors, of which one type is used for controlling the time-dependent switching of the second type of electrochemical processors used in the writing assembly.

Abstract: In the current invention peptides, which are derived from GLP-1 (glucagon-like peptide-1) and exendin-3 and/or exendin-4, are provided which bond to the GLP-1 receptor and can be used, labeled or unlabeled, for the production of an agent for diagnostic and therapy of benign and malignant diseases, in which GLP-1 receptor expression plays a role.

Abstract: The present invention provides methods for treating interstitial lung diseases, comprising administering to an individual an effective amount of an inhibitor of coagulation factor XII. The invention further provides uses and pharmaceutical kits for that treatment.

Abstract: The invention relates to a method for the fabrication of structures from an ion gel. In particular, the invention relates to a method, wherein the structures are fabricated by way of ink jet printing technology, which comprises the following steps of mixing at least one monomer with at least one ionic liquid to a printable liquid; generating the structure by printing the printable liquid using ink jet printing technique; and forming the polymer by means of polymerization, polyaddition or polycondensation of the structure; wherein common solvents are omitted.

Abstract: A functional PET imaging method is disclosed for differentiation between bilateral hyperplasia and unilateral adenoma comprising (1) introducing a radioactively labelled CYP11 B2 (aldosterone synthase) inhibitor which binds selectively to CYP11 B2 (aldosterone synthase) relative to CYP11 B1 (11?-hydroxylase) into a mammal with adrenal glands and (2) conducting positron emission tomography (PET) in the region of the adrenal glands to obtain a functional PET image of the adrenal glands. Also disclosed are radioactive tracer compounds suitable for use in this method, precursors for making the same, and a process for making the radioactive tracer compounds capable of being conducted as a rapid one-pot reaction.

Abstract: The invention relates to an optical security mark that can be applied to an object, said mark comprising a structure made of a metamaterial that generates a magnetic response to incident radiation having a wavelength (?) corresponding to a specific code of formula ?r(?) where ?r is the relative magnetic permeability of the metamaterial and ? is a wavelength of the incident radiation having a value of between 15 nm and 1100 nm, or a specific code of formula ?(?r) or combinations of said codes. Said mark has a first tranverse dimension bx in a first transverse extension of the metamaterial and a second transverse dimension by in a second transverse extension of the metamaterial, different from the first transversal dimension, the first transverse dimension and the second transverse dimension each being at least equal to the wavelength (?) of the incident radiation.

Abstract: The present invention relates generally to methods and compositions for reducing Interleukin-4 or Interleukin-13 signaling, in particular to treat asthma and atopic dermatitis. The inventors have found that Rac/PAK mediated endocytosis of the ligand bound type I (IL-4R with the chains IL-4Ra and IL-2-Rg) and/or type II receptor (IL-13R with the chains IL-4Ra and IL-13Ra1) is needed for the IL-4 and/or IL-13 mediated activation of downstream signalling events including phosphorylation of Stat family transcrition factors. These discoveries enable new methods of screening compounds that modulate Interleukin-4 and Interleukin-13 signalling, as well as new methods for treating conditions characterized by increased Interleukin-4 and Interleukin-13 levels. These conditions include inflammatory conditions, asthma bronchiale, atopic dermatitis, allergies, atopic syndromes, allergic rhinitis, and th2-induced conditions.

Abstract: Novel amino acids derivatives, in particular some amino acid amides derivatives, their process of preparation and their use for inhibiting Met-triggered disorders, in particular cancer.

Abstract: The present disclosure is directed, in part, to a curable composition, a method for augmenting a structure in a patient with a resorbable biocompatible polymer, and a biodegradable, resorbable implant comprising a biocompatible copolymer. An exemplary embodiment of the curable composition comprises (a) 60 wt. % to 95 wt. % of one or more vinyl ester monomers and/or vinylcarbonate monomers, wherein said one or more vinyl ester monomers and/or vinylcarbonate monomers are respectively selected from compounds of the general formulas (I) and (II) below: wherein n, m R1 and R2 have the meaning defined herein; (b) 0.1 to 40 wt. % of one or more multifunctional thiols; and (c) 0 to 10 wt. % of a biocompatible polymerization initiator.

Abstract: Described are compounds having a thiazolhydrazide scaffold, pharmaceutically acceptable salts of these compounds and pharmaceutical compositions containing at least one of these compounds together with pharmaceutically acceptable carrier, excipient and/or diluents. Said thiazolhydrazide compounds can be used for prophylaxis and/or treatment of neurodegenerative diseases and conditions.

Abstract: The present invention is related to a method of determining a test compound's ability to modify the biological activity of a GPR17. Said method comprises, among others, the step of contacting the test compound with a GPR17, or a functional GPR17 fragment in the presence of a suitable amount of a GPR17 agonist of formula I.

Abstract: The invention relates to an emergency release system for one or more pieces of winter sports equipment, such as skis, ski poles, snowboards, bindings and/or boots for skis or snowboards. It is equipped with a connection mechanism for detachably connecting at least two elements of one or more pieces of winter sports equipment, wherein the connection mechanism is supported substantially radially in or on one of the two elements, and a drive mechanism, which can be activated from outside and is suited for cancelling the radial support of the connection mechanism, accordingly causing the two elements to separate. The invention also relates to a release method and a manufacturing process for such an emergency release system.

Abstract: An implantable system for determining the accommodation requirement in an artificial accommodation system by optical measurement of the pupil diameter and the surrounding luminance, including at least one optical system, at least one data acquisition system that does not contact the ciliary muscle and measures a diameter of the pupil and luminance around at least one eye as a physical control signal for the accommodation requirement, at least one data processing system for generating an actuating signal for the optical system from the detected physical control signals or for the purpose of switching to the standby mode, at least one energy supply system, and at least one fixing system. The system has one sensor or a plurality of sensors with sensor elements for measuring the pupil diameter and the surrounding luminance.

Abstract: The present invention refers to pharmaceutical compositions comprising the soluble CD5 ectodomain and its use for the prevention and/or treatment of fungal infections and/or fungal sepsis, as well as inflammatory disorders of fungal origin.

Abstract: A membrane, especially for application in a sensor, which membrane includes a biocidal effect. The membrane comprises one or more components of the group consisting of: silver nano particles encapsulated in amphiphilic, core, shell structures, antimicrobial silanes, polymers with an antimicrobial end group, polyquads with modified end groups, and biocidally acting block copolymers. The membrane is resistant against aggressive agents, for example, corrosive or oxidizing cleaning agents, in the case of sterilizing, in the case of autoclaving, in the case of thermal loading and/or in the case of mechanical loading.

Abstract: A Fabry-Pérot tuneable filter device is described with reflecting elements separated by an optical path length to form an optical resonator cavity. A first actuator means is directly or indirectly coupled with a first reflecting element. And the first actuator means is configured to modulate the optical path length between first and second reflecting elements by a modulation amplitude to thereby sweep the optical resonator cavity through a band of optical resonance frequencies with a sweep frequency of 70 kHz or more. And the mechanical coupling between selected elements of the arrangement is sufficiently low such that when operated at the sweep frequency, the selected elements act as a system of coupled oscillating elements. In addition or alternatively, the first actuator means is directly or indirectly coupled with the first reflecting element so as to substantially drive the first reflecting element only.

Abstract: The present invention is directed to a animal feed for calves comprising calf-specific bacteria, optionally lipids, proteins, vitamins and/or mineral materials for conditioning of the intestinal flora in calves, and thus, for prophylaxis and/or treatment of diarrhea in calves.