Abstract: The present invention provides a scoliosis correction device comprising a pair of distraction rods (2, 3) and a member (4) for linking the distraction rods provided with means (8) for guiding each of the rods relative to each other inside said linking member. This device further comprises at least one member (6) for suspension of the distraction rods (2, 3) that can provide flexibility and exert a longitudinal pre-load on the rods in order to augment comfort and prevent vertebral arthrodesis of the spine of a patient instrumented with the correction device. Finally, it comprises a structure for cushioning and locking the distraction rods in translation in the linking member, said structure being active only when compressive forces are applied by the spine of a patient to the distraction rods (2, 3) so as to absorb and oppose said compressive forces and augment patient comfort, thereby preventing vertebral arthrodesis of the patient's spine.

Abstract: The present invention relates to a method for improving the production of an influenza virus, and in particular influenza vaccine seeds, or a vaccine directed against an influenza virus, characterized in that the production is carried out in the presence of an inhibitor of the interaction between the Mdm2 protein and the p53 protein.

Abstract: The present invention relates to a device for characterizing mechanical properties of a material (S) with a low modulus of elasticity, comprising an application surface (3) and a mechanical stressing mechanism (5), said mechanical stressing mechanism comprising: a mobile indenter (6) that can move at least in vertical translation so as to bear substantially normally on said material and on said application surface (3), at least one means (14) for translating said indenter along a vertical axis Z-Z? from a reference position in which the indenter is not in contact with the material (S) and at least one sensor (11) for measuring the load applied by the indenter on the material (S) along a direction normal to the application surface on the material, and at least one position sensor (20) able to determine the vertical position of said indenter (6) with respect to said reference position.

Abstract: A method and device for optical teledetection of compounds in a medium includes a detection measurement carried out by emitting into the medium, short pulses of light at least 3 nm wide, and detecting a part of the light back-scattered by the medium by means of a detection unit with temporal resolution. A reference measurement in which the light emitted or the light back-scattered is filtered by virtue of addressable filters, simulating the optical spectrum of the light at the working wavelengths of at least one given compound to be searched for. A comparison of the detection and reference measurements is made to deduce therefrom the possible presence of the compound or compound(s) searched for in the medium. The addressable filters are modified dynamically, and a series of reference measurements and corresponding comparisons are performed for a series of various compounds liable to be present in the medium.

Abstract: The present invention relates to a method for preparing carboxylic acids, in particular mono- and dicarboxylic acids, by oxidative cleavage of a vicinal diol. According to the invention, said method consists of reacting a vicinal diol of formula I: where: p is an integer comprised between 1 and 6; R1 and R2 are, separately: an alkyl or hydroxyl group having 1 to 12 carbon atoms; a —(CH2)n—C02M group where n, which can be identical or different in R1 and R2, is an integer comprised between 1 and 11 and M is a hydrogen atom or an alkyl group having 1 to 4 carbon atoms or an alkaline cation; or R1 and R2 jointly form an alkylene —(CH2)m- group where m is an integer comprised between 2 and 10, preferably between 2 and 6; with industrial-grade sodium hypochlorite (or bleach), in the absence of an organic solvent and without adding a catalyst, preferably at room temperature. The invention can be used for recycling natural vegetable oils.

Abstract: The present invention relates to a monoclonal antibody binding to the LG4/5 domain of chain alpha3 of human protein laminin-5, wherein said monoclonal antibody inhibits the binding of syndecan-1 to said laminin-5 alpha3 chain LG4/5 domain, in particular 1H12 monoclonal antibody produced by the hybridoma cell line named 1H12 deposited on Jan. 8, 2008 at the C. N. C. M. under number 1-3890, as well as chimerized, humanized derivatives and fragments thereof, and nucleic acid sequences encoding them, as well as vectors and host cells expressing them. The invention further relates to the medical application of such antibodies, in particular for treating cancer.

Abstract: An interconnected array of reconfigurable logic cells which carry out at least one logic function, externally connected to peripheral connection network equipped with switch boxes and connected to programmable input/output blocks. The logic cells are distributed in a first dimension in rows i with i=1 to d and a second dimension in columns j with j=1 to w, with d?2 and w=2 or d=2 and w?2, each logic cell including a second input, a second input, a first output and a second output, the first input of each logic cell and the first output of each logic cell being connected to the connection network, the second input and the second output of each logic cell being connected to other different column and row logic cells except for the first and last rows or columns for d>2 or w>2 respectively.

Abstract: The invention relates to a recombinant human factor IX (FIX) characterized in that said factor is obtained by a preparation method comprising, or even consisting of, the steps which consist in causing the genetic material encoding the FIX to be expressed in vitro in a human hepatocyte cell line Huh7, recovering the cellular supernatant in which the FIX was secreted and, optionally, purifying the synthesized FIX.

Abstract: A method for detecting at least one target molecule in a sample by mass spectrometry, comprising ionizing the molecules of the sample and then conducting the following steps (i) and (ii) n times, n being equal to 0, 1, 2, 3 or 4: (i) at least one ion obtained in the preceding step is selected, according to the target molecule, in a mass analyser, and (ii) the ion thus selected is fragmented in a fragmentation cell; trapping at least two different sampled ions, when n is zero, or when n is other than zero, in a mass analyser, the at least two ions thus trapped having a mass-to-charge ratio m/z characteristic of the target molecule; ejecting the trapped ions from the mass analyser; and detecting the ejected ions ejected by means of a detection device. The method is characterized in that the characteristic ions are ejected simultaneously and detected simultaneously.

Abstract: The present invention relates to a method for the quantitative detection of a target protein in a sample, in which the second-generation fragment ions are detected for providing a series of quantitative measurements, at least one of which is correlated to the amount of proteotypic peptide generated and to the amount of target protein in the sample, characterized in that the selected first-generation fragment ion having a mass (m/z)2 is a doubly-charged peptide having a proline and/or a histidine in position 1.

Abstract: The present invention relates to a method for preparing nanoparticles at least partially consisting of rare earth fluoride, characterized in that said fluoride is produced, in a solution, from a salt of the corresponding rare earth element and from a charge-transfer complex of formula (I), where Ra, Rb, and Rc are as defined in claim 1.

Abstract: Antibodies which specifically bind to a peptide having the sequence Ala-Ala-Ala-Pro-Ala-Lys-Ala-Ala-Ala-Ala-Pro-Ala-Lys-Thr-Ala-Ala-Ala-Pro-Val (SEQ ID No1), and which are not induced in a host following an infection of the host with T. cruzi.

Abstract: Synthetic peptide including the sequence KKLRIKSKEK (SEQ ID 1) or a sequence of identical size, in which the K residue (in position 1) and the R residue (in position 4) are conserved, the sequence being able to bind to the syndecan-1 receptor.

Abstract: The invention relates to a method for biologically combating the proliferation of Legionella pneumophila, with the exception of the treatment methods applied to the human or animal body, characterized in that it uses amoebic protozoa of the species Willaerita magna, corresponding to the strain deposited with the ATCC under number PTA-7824 or the strain deposited with the ATCC under number PTA-7825.

Abstract: The present invention relates to a drug comprising separately or together (i) a TLR3 ligand and (ii) a chemotherapeutic agent that acts on the intrinsic apoptotic pathway, for simultaneous or sequential administration in the treatment of cancer, wherein the chemotherapeutic agent is selected from topoisomerase II inhibitors, platinum-derived alkylating agents and PI3 kinase inhibitors.

Abstract: The present invention relates to a method for preparing fibers, notably of polysaccharide or collagen, by wet spinning under coagulation, said method notably comprising: a step for extruding a coagulable macromolecular assembly solution through a normal die; at least one partial coagulation cycle comprising a coagulation step on the one hand and a step for interrupting the coagulation on the other hand; and a step for receiving, notably by winding up, the obtained hollow fiber. The invention also relates to multi-membrane hollow fibers consisting of a same macromolecular assembly which may be spun by coagulation, notably a natural or modified natural polysaccharide in the physical hydrogel or partly dehydrated state. Said fibers including at least over their length two superposed coaxial membranes separated from each other by an inter-membrane space. The invention also relates to the spinning device for applying said method.

Abstract: The present invention relates to compounds of azapeptide or azapeptidomimetic type of formula (I): in which R1, R2, R3, X1, X2, X3, X4 and Y are as defined in claim 1, to pharmaceutical compositions containing them and to such compounds as adjuvant for an anticancer or anti-infectious medicament.

Abstract: A photon detecting device including a sensor including a vacuum chamber, a photocathode arranged therein to convert photons to primary electrons, a converter converting at least part of the energy of accelerated primary electrons to secondary charges collected by a plurality of detection cells, an acquisition circuit adapted to read the charges collected by the detection cells with an integration time allowing an impact density to be obtained per unit of time and per unit surface of a cell of the order of a single electron, a system identifying a cluster of adjacent detection cells of which at least one so-called main cell includes a quantity of collected charges higher than a threshold value, a system determining at least one characteristic of the cluster, a system memorizing at least one characteristic of a reference cluster resulting from conversion of a primary electron, and a system comparing the determined characteristic(s) of the cluster with the memorized characteristic(s) of the reference cluster to

Abstract: The present invention relates to a process for producing a structured porous material comprising a structured inorganic framework made up of metal-oxide based walls in which nanoparticles of metal 0 are incorporated, which comprises the following steps: a) formation of a suspension of hydrophilic nanoparticles of metal 0 stabilized by non-exchangeable ligands that give the nanoparticles their hydrophilic character; b) growth of the inorganic framework from an inorganic precursor around the nanoparticles of metal 0 stabilized by the non-exchangeable hydrophilic ligands, in the presence of a pore-forming agent; and c) elimination of the pore-forming agent and at least partially of the non-exchangeable ligands that give the nanoparticles their hydrophilic character.

Abstract: The invention relates to the use of a Myrica gale plant for producing a herbicidal agent or for preparing a herbicidal composition, and also to the corresponding herbicidal compositions and the herbicidal compositions containing a newly demonstrated herbicidal agent.