Abstract: The invention relates to a method for preparing an aqueous suspension of nanocapsules comprising an oily core surrounded by a polymeric shell, in which method the following phases are mixed: a) a first phase, called an oily phase, comprising: a hydrophobic polymer, an oil or a mixture of oils, at least one active ingredient, and a surfactant TA1, this oily phase being brought to a temperature T1 higher than the melting point of the hydrophobic polymer, the hydrophobic polymer being miscible, at this temperature T1, with the mixture of the surfactant TA1 and the oil or mixture of oils, and the active ingredient being miscible, soluble or solubilized in the mixture of the surfactant TA1 and the oil or mixture of oils; b) a second phase, called a polar phase, comprising a hydrophilic polymer in the form of a hydrogel in an aqueous solution containing a surfactant TA2, in such a way as to obtain the formation of the nanocapsules in an aqueous suspension.

Abstract: The present invention relates to a method and a device for determining the spatial configuration of molecules in particles or macromolecules or the shape of nanometric metallic particles. This method provides for the excitation of said particles or macromolecules placed in solution by way of two pulsed laser beams (E1, E2) that are identical but of different incidence I1, I2 with respect to the tested particles and then the detection of the photons of second-harmonic light (SHG) and the establishment of diagrams of polarization-resolved Hyper-Rayleigh scattering (HRS) intensity for each of the excitation beams. On the basis of each HRS diagram thus determined, a parameter ?E1, ?E2 is calculated for each beam, said parameter being characteristic of the spatial configuration of the molecules within the particles tested, which is determined by transferring the parameters calculated into a previously constructed diagram ?E2=f(?E1).

Abstract: A method for manufacturing a field sensor including a series of n probes, in which n>=3, each formed of a core of magnetic alloys associated with a coil. According to the invention, the method includes the steps of ensuring the deposit of cores of magnetic alloys onto a non-magnetic substrate, on at least part or the entirety of a surface corresponding to a series of n strips extending along axes (x, y, z) concurrent at an intersection and connected by an intersection region (z), before or after this deposit, cutting out the n strips in the substrate leaving them connected to the substrate by at least one attachment, assembling each strip with a coil, and folding at least one strip along a fold line perpendicular to the axis thereof.

Abstract: The invention concerns an installation for the high-speed acquisition of acquisition data via an Ethernet network (2) with several nodes (N), where at least one of the nodes of the Ethernet network constitutes a client/server detection unit (3) with at least one detector (4) delivering acquisition data. According to the invention each detection unit (3) includes: self-triggering resources for reading the acquisition data so that the said detection unit (3) is able to operate independently, reading and processing resources that are independent of the other nodes, resources for transmission of the acquisition data via the network (2), to at least one other node (N). and a clock unit allowing correlation between the clocks of the detection units, where each clock unit has resources for receiving a clock synchronisation signal, resources for transmission to the transmitting clock unit, and resources for processing the encoded instructions.

Abstract: The present invention relates to a method for preparing by wet spinning a continuous filament based on hyaluronic acid in free acid form, notably soluble in water. The preparation method according to the invention comprises the following steps: a) preparing a spinnable aqueous solution of hyaluronic acid or of a hyaluronic acid salt, preferably a sodium hyaluronate solution; b) extruding said solution to an extrusion die; c) forming the filament by passing the extruded solution into a bath of acetic acid, concentrated to more than 80%, drawing and drying. The invention also relates to a filament based on hyaluronic acid in free acid form, said filament having swelling properties in water and physiological liquids and moreover being solubilizable in water under certain conditions.

Abstract: A device for in vivo dosimetry, the device comprising: a miniature probe (1) comprising at least: a radioluminescent material (3) that emits a radioluminescence signal of intensity that is a function of the high-energy radiation irradiating said material; and an optical fiber (4, 16) receiving the luminescence signal and conveying it to a luminescence detector system (14); and a luminescence detector system (14); the device being characterized in that the radioluminescent material (3) is gallium nitride (GaN) that emits a luminescence signal at least in a narrow band BE, and in that the luminescence detector system (14) includes an optical device (18) enabling the narrow emission band of gallium nitride to be selected.

Abstract: The invention relates to a process for modifying the properties of a thin layer (1) formed on the surface of a support (2) forming a substrate (3) utilised in the field of microelectronics, nanoelectronics or microtechnology, nanotechnology, characterised in that it consists of: forming at least one thin layer (1) on a nanostructured support with specific upper surface (2), and treating the nanostructured support with specific upper surface (2) to generate internal strains in the support causing its deformation at least in the plane of the thin layer so as to ensure corresponding deformation of the thin layer to modify its properties.

Abstract: The invention relates to a process for the preparation of dispersible colloidal systems in the form of nanocapsules whose wall consists of a polymer obtained by the polycondensation of two monomers, ? and ?, and whose core consists of a substance B, characterized in that: (1) a first liquid phase is prepared which consists of a solution of monomer ? in a solvent or solvent mixture and contains one or more surfactants and the substance B in solution or suspension; (2) a second liquid phase is prepared which consists of a non-solvent or non-solvent mixture for the monomer ? and contains the monomer ? and one or more surfactants, the solvent or solvent mixture of the first phase being miscible in all proportions with the non-solvent or non-solvent mixture of the second phase; (3) the first phase is added to the second, with moderate agitation, to give a colloidal suspension of nanocapsules, agitation being maintained until the monomers ? and ? have completely polymerized; and (4) if desired, all or part of th

Abstract: The method of the invention for extracting electrons in a vacuum consists in: making a cathode presenting at least one junction (9) between a metal (7) acting as an electron reservoir and an n-type semiconductor (8) possessing a surface potential barrier with a height of a few tenths of an electron volt, and presenting thickness lying in the range 1 nm to 20 nm; injecting electrons through the metal/semiconductor junction (9) to create a space charge in the semiconductor (8) sufficient to lower the surface potential barrier of the semiconductor to a value that is less than or equal to 1 eV relative to the Fermi level of the metal (7); and using the bias source creating an electric field in the vacuum to control the height of the surface potential barrier (Vp) of the n-type semiconductor in order to control the emission of the electron flux towards the anode.

Abstract: The invention pertains to the field of structural biology and relates to a process to compare various three-dimensional (3D) structures and to identify functional similarities among them. The process of comparison of 3D atomic structures of the invention is based on the comparisons of defined chemical groups onto the 3D atomic structures and allows the detection of local similarities even when neither the fold nor sequence for example aminoacid sequences for polypeptides sequences or nucleotide sequences for nucleic acid sequences are conserved. This process requires the attribution of selected physico-chemical parameters to each atom of a 3D atomic structure, then the representation of each 3D atomic structure by a graph of chemical groups.

Abstract: A process for the preparation of nanoparticles for the encapsulation of active constituents, the nanocapsules prepared being dispersible in aqueous phase in colloidal form, non-toxic, biocompatible, stable in colloidal suspension and economical. In the process, two non-oily solvents as used, together with a third, oily solvent.