Abstract: A scapholunate stabilisation implant includes a central part having an elastic deformation capacity enabling the traction movements of the implant, and two end parts having an elastic deformation capacity enabling the torsional movements of the implant, the end parts being provided with at least one hole through which the fixing screw is passed, the central part and the end parts being connected by rods that can withstand the torsional deformations of the implant.

Abstract: The invention relates to BTLA antibodies that block BTLA-HVEM interaction and uses thereof.

Abstract: The present invention relates to a method of using a TAFA4 protein or an agonist thereof for preventing, alleviating or treating pain in a subject. In one embodiment, the invention provides a method of treating pain in a subject by administering a TAFA4 protein or an agonist thereof to the subject. The TAFA4 can have the amino acid sequence of SEQ ID NO: 1 or 2 or a sequence having at least 90% sequence identity to SEQ ID NO: 1 or 2. The TAFA4 agonist can also be a peptide comprising 10 to 60 consecutive amino acid residues of SEQ ID NO: 1 or 2. Also described herein are pharmaceutical compositions, their preparation and uses as well as methods for preventing, alleviating or treating pain using such compounds and compositions.

Abstract: The present invention relates to a method of assessing proprioceptive status by calculating a proprioceptive score Sp from absolute and variable errors between target angles and angles estimated and joint motion detection by the person tested, and/or between measured time of perceived movement of the joint of the tested person these proprioceptive scores of a person being associated with an assessment date and then stored with a date so as to serve as a reference when said person is monitored or when there is a comparison of said person with at least another person. The present invention also concerns an apparatus for the proprioceptive assessment of at least one joint, this apparatus having two movable parts (8, 9) with drive means (12, 15) particular for the pivoting of the movable parts (8, 9), means of determining the pivot angle for each of the first and second parts (8, 9) also being provided. Applications are in the field of proprioceptive assessment by movement of a limb of a person.

Abstract: According to one aspect, the invention concerns a device for transporting and controlling light pulses for lensless endo-microscopic imaging and comprises: a bundle of N monomode optical fibers (F1) arranged in a given pattern, each monomode optical fiber being characterized by a relative group delay value (Ax) defined relative to the travel time of a pulse propagating in a reference monomode optical fiber (F0) of the bundle of fibers (40), an optical device for controlling group velocity (50) comprising a given number M of waveplates (Pj) characterized by a given delay (8tj); a first spatial light modulator (51) suitable for forming from an incident light beam a number N of elementary light beams (Bi) each of which is intended to enter into one of said optical fibers, each elementary beam being intended to pass into a given waveplate such that the sum of the delay introduced by said waveplate and the relative group delay of the optical fiber intended to receive said elementary light beam is minimal in abs

Abstract: A method of assisting visual exploration for individuals suffering from a retinal condition resulting in a scotoma and, more particularly, a method S for assisting visual exploration by such an individual of a digital image on a display device, the method including: —recognizing, using shape recognition software, at least one object contained in an object area of the digital image, —determining a blind area in the image, corresponding to a position of the scotoma in the field of vision of the user looking at the image, —if the blind area and the object area are detected to be in close proximity to each other, applying image processing to the image consisting in highlighting the object area for the user.

Abstract: A method for producing a device for detecting flux of neutrons with parameters in predetermined ranges, including: one phase of determining parameters, including: simulating penetration of a flux of incident neutrons with parameters in the predetermined ranges through a modelled stack including in succession and in order at least: one first electrode; one substrate including: a first layer; and a second layer; and one second electrode; and simulating at least one defect peak created in the first layer by vacancies and/or ionization of the particles generated by collisions between neutrons of the flux of incident neutrons and atoms of the second dopant species; and identifying depth of the defect peak closest the interface between the first and second layers of the modelled stack.

Abstract: The present invention relates to a method for estimating the thermophysical properties of a material (?) that incorporates at least one temperature sensor (1, 2, 3) and one point heat source (4), the distance between the at least one temperature sensor (1, 2, 3) and the point heat source (4) being known. The method includes the steps of: expression of the theoretical temperature as a function of time at the at least one temperature sensor (1, 2, 3) when the point heat source (4) is activated, said expression depending on the thermophysical parameters of the material (?); acquisition of a plurality of temperature measurements by the at least one temperature sensor (1, 2, 3) over a time period during which the point heat source (4) is activated; and determining of the values of the thermophysical parameters of the material (?), such that the difference between the theoretical temperatures obtained via said expression and the temperatures that are actually measured is minimal.

Abstract: The present invention relates to piperazine phenothiazine derivatives useful as therapeutic agents for treating spasticity, particularly following an ischemia or traumatic injury, or compression syndrome. The invention further relates to a pharmaceutical composition comprising a compound of the invention for treating spasticity.

Abstract: The invention relates to the technical field of measuring electric and magnetic properties, and specifically relates to a sample holder (1) to be connected to a device (2) for supporting a sample holder in order to measure the dielectric and/or magnetic properties of a sample (3), said supporting device (2) comprising: first and second connectors (4, 5) suitable for allowing an electromagnetic wave to pass therethrough, and for being connected to a means (6) for transmitting the electromagnetic wave and to a means (7) for circulating the electromagnetic wave after passing through the supporting device (2) and the sample holder (1), respectively, which is suitable for transmitting all or part of the electromagnetic wave from the first connector (4) to the second connector (5) according to a reference axis (x) and for being removably arranged therebetween, the sample holder (1) comprising an outer tubular body (11) that is coaxial to said reference axis (x), and a cavity (8) in which the sample (3) is to be hou

Abstract: A motion sensor assembly is adapted to determine an angular velocity of a moving contrast in its field of view. The motion sensor assembly includes: a motion sensor with a first and a second analog photoreceptor each adapted for observing the moving contrast, the first and the second photoreceptors being separated by a predetermined interreceptor angle; and an angular velocity calculating unit connected to the first and second photoreceptors for calculating the angular velocity of the moving contrast based on a first and a second analog signal delivered by the first and the second photoreceptors, respectively. The first and the second analog signals delivered by the first and the second photoreceptors at are sampled a given sampling frequency to obtain a first and a second digital signal, respectively. An interpolator is configured to interpolate the first and the second digital signals upon their crossing a predetermined threshold between successive samples.

Abstract: A device for the imaging of an object to be studied, combines: a prism made from a material with no losses (non-absorbent) for radiation in the microwave range; a sample holder on a front face of the prism for receiving the object to be studied; and a mobile emitting antenna on a rear face of the prism in order to emit radiation in the microwave range.

Abstract: The present invention relates to a method of interpreting different antibiogram images in which it is possible to recognize a phenotype of bacterial resistance relative to antibiotics by comparing photographs using a photographic image bank of the reference antibiogram without any need to interpret them using the EUCAST or CA-SFM interpretation data; providing that for a given phenotype, there is available a collection of photographs of a plurality of bacteria of the same species and of the same phenotype.

Abstract: An attenuation device for attenuating sound waves, and a corresponding system and method, generated by a source emitting sound waves having frequencies between f1 and f2 and wherein the pressure levels are between n1 and n2. The attenuation device comprising at least one acoustic absorber comprising at least one non-linear membrane; the attenuation device being configured in such a way that the first face of the absorber is in acoustic communication with the source. The attenuation device also comprises at least one coupling element for coupling the second face with the source, the coupling element being configured to transmit to the second face sound waves according to the sound waves emitted by the source, and of which the phase and/or the amplitude leads to a pressure differential of the sound waves arriving respectively on the first and second face at the same time.

Abstract: A method for detecting the presence of an analyte (1) in a solution (2) comprising: providing at least a first and a second probes (A, B) different from each other, each probe (A,B) comprising a nanoparticle conjugated with a receptor specific to the analyte (1); contacting the solution (2) suspected of including the analyte (1) with the first and the second probes (A, B) to form a sample solution (3), wherein the sample solution (3) comprises aggregates (4) comprising the analyte (1) combined with the first and the second probes (A, B); illuminating the sample solution (3) with a light source having at least a first and a second exciting wavelengths (?eA, ?eB) different from each other wherein the first and the second wavelength are chosen to get specific optical responses from the first probe (A) and the second probe (B) respectively when illuminated; detecting as a function of time the light scattered by the first probe (A) at a first detection wavelength (?dA) and the light scattered by the second probe (

Abstract: The present invention concerns a composition comprising at least three peptides derived from Mycobacterium tuberculosis antigen Rv2626c, its use in the diagnostic of latently infected Mycobacterium tuberculosis (LTBI) subjects, corresponding methods of use and kits.

Abstract: The invention provides a novel method of preparing a capture phase for detecting and/or quantifying a target biological entity, said capture phase including a biological ligand for the biological entity, said biological ligand being covalently bonded to an amphiphilic polymer and being immobilized on a solid support, the method being characterized in that the biological ligand is immobilized on the solid support by bringing the solid support into contact with a dispersion of micelles formed by a plurality of chains of the amphiphilic polymer, said micelles carrying a plurality of molecules of the biological ligand on the surface thereof. The invention also provides corresponding capture phases and associated detection methods and kits.

Abstract: The present invention concerns an oligonucleotide modified by substitution at the 3? or the 5? end by a moiety comprising at least three saturated or unsaturated, linear or branched hydrocarbon chains comprising from 2 to 30 carbon atoms, and the use therefore as a medicament, in particular for use for treating cancer.

Abstract: The present invention concerns an oligonucleotide modified by substitution at the 3? or the 5? end by a moiety comprising at least one ketal functional group, wherein the ketal carbon of said ketal functional group bears two saturated or unsaturated, linear or branched, hydrocarbon chains comprising from 1 to 22 carbon atoms, and the use therefore as a medicament, in particular for use for treating cancer.

Abstract: The present invention relates to the use of a compound chosen from squalamine and a squalamine-analog aminosteroid compound as agent for disinfecting an inert material object, in particular for the pre-disinfection of medical, dental, diagnostic or surgical equipment. The present invention also provides an aqueous or water-soluble disinfecting composition beneficial for a use according to the invention, characterized in that as disinfecting active compound it comprises a said antibacterial and antifungal compound selected from squalamine and a said squalamine-analog aminosteroid compound and suitable excipients for a water-soluble or aqueous formulation.