Abstract: A device for the imaging of an object to be studied, combines: a prism made from a material with no losses (non-absorbent) for radiation in the microwave range; a sample holder on a front face of the prism for receiving the object to be studied; and a mobile emitting antenna on a rear face of the prism in order to emit radiation in the microwave range.

Abstract: The invention relates to antigen peptide derived from the Nectin4 and its use for preventing and treating cancer.

Abstract: The subject matter of the invention is a pipe (2) forming part of a heat exchanger. The pipe (2) is delimited by at least one wall (4, 7) for separating a fluid (3) circulating in the pipe (2) and an external medium (6). The wall (4, 7) is equipped with means (8) of deforming the wall (4, 7). These arrangements are such that at least one of the walls (4, 7) of the pipe (2) is actively deformed, in a precise and controlled manner, by the deformation means (8) in order to precisely conform and configure said, wall (4, 7), the use of the deformation means (8) being in particular placed under the influence of control means in relationship with the deformation means (8).

Abstract: The present invention relates to a method of assessing proprioceptive status by calculating a proprioceptive score Sp from absolute and variable errors between target angles and angles estimated and joint motion detection by the person tested, and/or between measured time of perceived movement of the joint of the tested person these proprioceptive scores of a person being associated with an assessment date and then stored with a date so as to serve as a reference when said person is monitored or when there is a comparison of said person with at least another person. The present invention also concerns an apparatus for the proprioceptive assessment of at least one joint, this apparatus having two movable parts (8, 9) with drive means (12, 15) particular for the pivoting of the movable parts (8, 9), means of determining the pivot angle for each of the first and second parts (8, 9) also being provided. Applications are in the field of proprioceptive assessment by movement of a limb of a person.

Abstract: Provided are compounds of formula (I): wherein R1, R2, R3, R4 and R5 are independently selected from the group comprising, inter aliae, H, optionally substituted, branched or linear C1-C12 alkyl, halogen atom and C1-C12 haloalkyl, and wherein A represents a single bond or an optionally substituted C1-C6 alkylene radical, notably useful for the treatment of human cancers.

Abstract: The invention relates to a method and a system for estimating the resemblance between two images of optionally different modalities. More particularly, the invention makes it possible to characterize a similarity between two binary images according to a formula that allows registration of images acquired in the fields of teledetection, medical imaging, and industrial vision.

Abstract: The invention concerns an in-vitro method for introducing a targeted genome modification into an oocyte or an egg and a method for performing a random insertion in the genome of a host cell.

Abstract: The present invention relates to compound of formula (I), their method of preparation and use thereof in particular in the fields of optoelectronic, photonic, photovoltaics and biology.

Abstract: A resistive device which includes at least one strain gauge (12, 14) comprising silicon nanowires, a power supply (16) that has at least one current source (22, 24) able to generate a current (Ibias) for biasing the strain gauge; and acquisition means (18) able to deliver a measurement signal which can be used to determine the variation in the electrical resistance of the gauge is provided. The power supply includes a chopper (26) allowing the biasing current generated by each current source to flow through each gauge only during a fraction of an operating cycle of the device.

Abstract: The invention relates to a device (1) for connecting/disconnecting a submersible connector (100) provided with a male portion (101) and a female portion (102), to a related connection/disconnection method, as well as to the various possible uses of said device. The device includes means (11, 12) for moving said male and/or female portions of the connector (100) between a connection position and a disconnection position, and vice versa, and is characterized in that the device further includes a system (16) for injecting a fluid (20) around said male (101) and female (102) portions of the connector (100) when the latter is moved from the connection position to the disconnection position and vice versa, in order to insulate the male and female portion from the water surrounding the connector (100), the injection system (16) being located outside the connector (100).

Abstract: The present invention relates to compound of formula (I), their method of preparation and use thereof in particular in the fields of optoelectronic, photonic, photovoltaics and biology.

Abstract: The invention relates to the use of a hydroxymethylglutaryl-coenzyme A (HMG-CoA) reductase inhibitor and of a farnesyl-pyrophosphate synthase inhibitor, or of one of their associated physiologically acceptable salts, in the preparation of a composition, particularly a pharmaceutical composition, for use in the treatment of human or animal, pathological or nonpathological situations related to the accumulation and/or the persistence of prenylated proteins in cells, such as during progeria (Hutchinson-Gilford syndrome), restrictive dermopathy or physiological ageing.

Abstract: The present invention relates to a method for measuring the angular position of a contrasting edge of an object having a luminance transition zone which is substantially rectilinear in a given direction and separates two regions of different luminances. This method comprises the functional steps of: —carrying out, in a transverse direction different from the given direction, an amplitude modulation of the signals delivered by a first and a second optical sensor; and —calculating an output signal (Yout(t)) starting from the signals delivered by the first and the second optical sensors (D1, D2) as a function of the angular position of the luminance transition zone. Device and set of devices for measuring the angular position of a contrasting edge and steering aid system for fixation and tracking a target comprising at least one such contrasting edge.

Abstract: Cyclic beta glucan compounds function as an immunoadjuvant when administered prior to, concommitantly with, or subsequent to the administration of one or more antigens to a subject. These adjuvant compounds may be effectively used as dendritic cell activating molecules.

Abstract: The invention relates to novel functional amphiphilic molecule or macromolecule formulations with multiple compartments for transporting or targeting at least one therapeutic agent, in particular an antitumor agent, as well as to a method for preparing such formulations and to the use thereof.

Abstract: The disclosure relates to a method for generating UWB waveforms, each comprising a sequence of pulses, the method comprising: generating consecutive elementary pulses having durations corresponding to setpoint durations and a constant amplitude, amplifying each elementary pulse separately as a function of a respective setpoint amplitude, and combining the amplified elementary pulses to obtain a waveform successively comprising each of the amplified alternately positive and negative, elementary pulses.

Abstract: The invention relates to Gram-negative bacteria carrying an inactivated gene encoding a glycosyltransferase involved in the synthesis of the core of the LPS of said Gram-negative bacteria, wherein said inactivated gene results in the synthesis of a LPS having a modified core. These strains have an attenuated virulence but induce a humoral immunity sufficient for ensuring vaccination of the host.

Abstract: The present invention relates to the field of organic chemistry and in particular to organic free radicals used as polarizing agents in the technique of Dynamic Nuclear Polarization (DNP), which involves transferring the polarization of electron spins to the nuclei of a compound whose Nuclear Magnetic Resonance (NMR) is being observed. It concerns Dinitroxide-type Biradical polarizing agents characterized by a rigid linkage between the aminoxyl groups of said nitroxide units. This particular structure enables, at low temperatures and high fields, optimal transfer of polarization and optimal enhancement of NMR/MAS signals of the polarized nuclei of the compound studied.

Abstract: The invention relates to antibodies binding to the proteins forming adrenomedullin receptors, and to the uses thereof as a drug.

Abstract: The present invention relates to the general field of the treatment and prevention of diseases involving an inflammatory condition, namely sepsis or infectious or viral diseases as well as diseases requiring for the of treatment an immunosuppressive activity namely autoimmune diseases and graft rejection. In particular, the invention relates to an inhibitor of the activity or the formation of the PP1/GADD34 complex for the treatment of a condition requiring an immunosuppressive activity or an anti-inflammatory activity.