Patents Assigned to Universite d'Aix-Marseille
  • Polymers containing grafted bis(sulfonyl)imide sodium or lithium salts, methods for production thereof and uses of same as electrolytes for batteries
    Patent number: 10141603
    Abstract: The invention relates to novel polymers containing grafted sodium or lithium bis(sulfonyl)imides, to the methods for the production thereof, and to the uses of same as electrolytes in batteries.
    Type: Grant
    Filed: July 20, 2015
    Date of Patent: November 27, 2018
    Assignees: CPD INNOVATION, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE, UNIVERSITE D'AIX MARSEILLE
    Inventors: Jean-Roger Desmurs, Elisabet Dunach Clinet, Philippe Knauth, Vincent Morizur, Sandra Olivero
  • NON-VOLATILE MEMORY ALLOWING A HIGH INTEGRATION DENSITY
    Publication number: 20180331115
    Abstract: The invention relates to a non-volatile memory that comprises selection transistors. Each selection transistor includes a layer of semiconductor material with a channel region and conduction electrodes, a gate stack including a gate electrode and a gate insulator, an isolation trench between the transistors, a storage structure of the RRAM type comprising a control electrode, and a dielectric layer formed under the control electrode and in the same material as the gate insulator, comprising a central part directly above the isolation trench and ends extending directly above conduction electrodes, and configured so as to form conducting filaments. The said storage structure and the said selection transistors are formed in the same pre-metallization layer.
    Type: Application
    Filed: May 11, 2018
    Publication date: November 15, 2018
    Applicants: Commissariat a l'energie atomique et aux energies alternatives, Universite d'Aix-Marseille
    Inventors: Jean-Michel Portal, Marios Barlas, Laurent Grenouillet, Elisa Vianello
  • ANTI- NKG2D SINGLE DOMAIN ANTIBODIES AND USES THEREOF
    Publication number: 20180327499
    Abstract: The present invention relates to anti-Natural Killer Group 2 member D (NKG2D) single domain antibodies and uses thereof in particular in the therapeutic field.
    Type: Application
    Filed: November 10, 2016
    Publication date: November 15, 2018
    Applicants: INSERM (INSTITUT NATIONAL DE LA SANTÉ ET DE LA RECHERCHE MÉDICALE), UNIVERSITÉ D'AIX MARSEILLE, INSTITUT JEAN PAOLI & IRENE CALMETTES, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS (CNRS)
    Inventors: Daniel BATY, Patrick CHAMES, Brigitte KERFELEC, Elise TERMINE
  • Polymers containing sulfonamide sodium or lithium salts, methods for production thereof and uses of same as electrolytes for batteries
    Patent number: 10109883
    Abstract: The invention relates to novel polymers containing grafted sodium or lithium sulphonamides, production methods thereof and uses of same as electrolytes in batteries.
    Type: Grant
    Filed: July 20, 2015
    Date of Patent: October 23, 2018
    Assignees: CPD INNOVATION, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE, UNIVERSITE D'AIX MARSEILLE
    Inventors: Jean-Roger Desmurs, Elisabet Dunach Clinet, Philippe Knauth, Vincent Morizur, Sandra Olivero
  • Method for identifying the anisotropy of the texture of a digital image
    Patent number: 10089748
    Abstract: A method for determining an extent of anistropy of texture of an image in a manner that avoids inaccuracies arising from interpolation.
    Type: Grant
    Filed: September 17, 2015
    Date of Patent: October 2, 2018
    Assignees: UNIVERSITÉ D'AIX-MARSEILLE, Centre National de la Recherche Scientifique
    Inventor: Frédéric Joseph Pierre Richard
  • Chimeric peptide that interacts with cell membrane gangliosides
    Patent number: 10087226
    Abstract: The invention relates to a chimeric peptide displaying the ganglioside-binding properties of both ?-synuclein and ?-amyloid peptide. Such peptide is useful in preventing or treating any condition which involves gangliosides as cell surface receptor sites, including neurodegenerative disorders, infectious diseases, or tumors.
    Type: Grant
    Filed: March 10, 2015
    Date of Patent: October 2, 2018
    Assignee: Universite D'Aix-Marseille
    Inventors: Jacques Fantini, Nouara Yahi
  • Method for labeling specifically living and bacteria comprising the use of modified monosaccharide compounds
    Patent number: 10082509
    Abstract: The invention relates to a method for labeling specifically living bacteria of a given category of Gram negative bacteria in a sample comprising bacteria, the method including the steps of: a) incubating the bacteria of the sample with at least one modified monosaccharide compound having a first reactive chemical group capable of reacting with a second reactive group, so that a monosaccharide residue bearing the first reactive group is incorporated into the polysaccharides of the outer membrane of such bacteria, and b) contacting the modified monosaccharide residue incorporated within the outer membrane of the bacteria, with a labeling molecule having a second reactive group.
    Type: Grant
    Filed: October 29, 2014
    Date of Patent: September 25, 2018
    Assignees: CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE, UNIVERSITE D'AIX-MARSEILLE
    Inventors: Sam Dukan, Boris Vauzeilles, Aurelie Baron, Jordi Mas Pons
  • Sulfolobal phosphotriesterase-like (PLL) lactonases activity having enhanced properties and the uses thereof
    Patent number: 10072252
    Abstract: Mutated hyperthermophilic PTE having a lactonase activity derived from a hyperthermophilic phosphotriesterase corresponding to the consensus sequence of SEQ ID NO: 1, the mutated PTE including the at least one mutation chosen amongst 53 putative positions and the mutated PTE having enhanced properties. Also provided are compositions including the mutated hyperthermophilic PTE and the uses thereof, notably as bioscavenger of organophosphate compounds or as quorum quencher of the bacteria using lactones to communicate.
    Type: Grant
    Filed: April 14, 2014
    Date of Patent: September 11, 2018
    Assignees: CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE, UNIVERSITE D'AIX-MARSEILLE
    Inventors: Eric Chabriere, Mikael Elias, Julien Hiblot, Didier Raoult
  • Compositions useful in the diagnostic of latently infected
    Patent number: 10067147
    Abstract: The present invention concerns a composition comprising at least three peptides derived from Mycobacterium tuberculosis antigen Rv2626c, its use in the diagnostic of latently infected Mycobacterium tuberculosis (LTBI) subjects, corresponding methods of use and kits.
    Type: Grant
    Filed: August 28, 2015
    Date of Patent: September 4, 2018
    Assignees: Centre National de la Recherche Scientifique (C.N.R.S.), Conicet (Consejo Nacional de Investigaciones Cientificas y Tecnicas, Institut Jean Paoli & Irene Calmettes, Universite d'Aix-Marseille, Institut National de la Sante et de la Recherche Medicale (INSERM)
    Inventors: Juan Iovanna, Virginia Pasquinelli, Maria Madgalena Gherardi, Hector Eduardo Chuluyan, Ana Inès Rovetta, Delfina Pena, Véronica Edith Garcia
  • Method and device for in-flight terrain identification for microdrone
    Patent number: 10061319
    Abstract: The invention relates to a surface identification device for the movement of a vehicle at a distance from that surface, the device comprising a detection head, the head including at least one sensor of a property depending on the distance of the center of the head from the surface, each sensor covering a detection zone centered on a line of sight, an orientation system for the detection zone of each sensor, and a controller processing the signals from each sensor and controlling the system based on said signals. The controller estimates the direction of the perpendicular to the surface, and uses said system to rotate the line of sight of each sensor in a separate direction by a reorientation angle of the direction of said perpendicular.
    Type: Grant
    Filed: October 16, 2014
    Date of Patent: August 28, 2018
    Assignees: UNIVERSITE D'AIX-MARSEILLE, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE
    Inventors: Franck Ruffier, Fabien Expert
  • Method and pharmaceutical composition for use in the treatment of epilepsy
    Patent number: 10016424
    Abstract: The present invention relates to a compound which is an antagonist of the GluK2/GluK5 receptor or an inhibitor of the GluK2/GluK5 receptor expression for use in the treatment or the prevention of epilepsy.
    Type: Grant
    Filed: September 16, 2014
    Date of Patent: July 10, 2018
    Assignees: INSERM (INSTITUT NATIONAL DE LA SANTÉ ET DE LA RECHERCHE MÉDICALE, UNIVERSITÉ D'AIX MARSEILLE, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS), UNIVERSITE DE BORDEAUX
    Inventors: Valerie Crepel, Christophe Mulle, Angelique Peret
  • Method for producing methane by means of aerobic co-culture of anaerobic micro-organisms
    Patent number: 10011852
    Abstract: The present invention relates to the biological production of methane (Biogas) by co-culture in an aerobic atmosphere of a methanogenic bacterium and of an anaerobic bacterium capable of producing hydrogen, in a culture medium comprising or being supplemented with carbohydrate compound(s), notably starch and/or sugars, and supplemented with antioxidant compound(s).
    Type: Grant
    Filed: April 20, 2015
    Date of Patent: July 3, 2018
    Assignees: FONDATION MEDITERRANEE INFECTION, UNIVERSITE D'AIX MARSEILLE, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS), INSERM (INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE)
    Inventors: Didier Raoult, Saber Khelaifia, Michel Drancourt
  • Antagonist of the BTLA/HVEM interaction for use in therapy
    Patent number: 10005839
    Abstract: Antagonist of the BTLA/HVEM interaction for use in therapy The present invention relates to an antagonist of the BTLA/HVEM interaction for use in therapy, wherein said antagonist increases the proliferation of V?9V?2 T cells.
    Type: Grant
    Filed: February 21, 2014
    Date of Patent: June 26, 2018
    Assignees: INSERM (INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE), INSTITUT JEAN PAOLI & IRENE CALMETTES, UNIVERSITE D'AIX-MARSEILLE, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE—CNRS
    Inventors: Daniel Olive, Christine Pasero, Julie Gertner-Dardenne
  • IDENTIFICATION OF BACTERIA THAT ARE RESISTANT TO CARBAPENEMS BY MEMBRANE IMPERVIOUSNESS
    Publication number: 20180155757
    Abstract: A method for discriminating carbapenem-resistant bacteria according to whether or not they develop resistance by membrane impermeability, the method including the following steps: providing a bacterial strain that is resistant to at least one carbapenem, evaluating the sensitivity of the bacterial strain with regard to at least one indicator carbapenem, on the one hand in the absence of polymyxin B nonapeptide (PMBN) and, on the other hand, in the presence of PMBN in a non-inhibitory concentration, establishing a prognosis of resistance by membrane impermeability in the case where the presence of PMBN makes it possible to significantly increase the sensitivity of the bacterial strain with regard to at least one indicator carbapenem used.
    Type: Application
    Filed: May 19, 2016
    Publication date: June 7, 2018
    Applicants: BIOMÉRIEUX, INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM), UNIVERSITE D'AIX MARSEILLE, SERVICE DE SANTÉ DES ARMÉES (SSA)
    Inventors: Christine FRANCESCHI, Elisabeth PINET, Jean-Marie PAGES, Gilles ZAMBARDI
  • Non-destructive detection method of charged particles without mass limitation
    Patent number: 9989464
    Abstract: A non-destructive method for detecting charged particles, includes measuring a reference value of at least one physical parameter of an ion cloud confined in an ion trap; performing an injection of a sample in the ion cloud confined in the ion trap, the sample crossing the ion cloud and getting out the ion cloud without being trapped inside the ion trap; measuring a first experimental value of the at least one physical parameter of the ion cloud; and comparing the first experimental value with the reference value in order to determine the presence of at least one charged particle in the sample, or the absence of any charged particle in the sample.
    Type: Grant
    Filed: September 25, 2015
    Date of Patent: June 5, 2018
    Assignees: CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS), UNIVERSITE D'AIX-MARSEILLE
    Inventors: Caroline Antoinette Madeleine Champenois, Laurent Hilico, Christophe Michel René Jouvet, Jofre Pedregosa Gutierrez, Martina Knoop, Claude Dedonder-Lardeux
  • Reactor usable for decontamination of fluids and method of use
    Patent number: 9981862
    Abstract: The invention relates to a method for the decontamination of contaminated liquid, as well as a reactor for implementing a decontamination method. The method comprises a step of mixing the contaminated liquid under stirring with at least one persulphate ion with the exception of ammonium persulphate, and at least iron, an iron atom or an iron ion in its ferrous or ferric form at a concentration between 50 ?M and 600 ?M, preferably between 100 ?M and 400 ?M, a second step in which the mixture obtained is subjected for a sufficient time to at least one UV/visible irradiation having a narrow wavelength spectrum comprised between 153 nm and 560 nm.
    Type: Grant
    Filed: October 26, 2012
    Date of Patent: May 29, 2018
    Assignees: UNIVERSITE D'AIX MARSEILLE, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS)
    Inventors: Stephane Barbati, Serge Chiron, Moussa Mahdi Ahmed, Hichem Bouzidi
  • Antibodies directed against ICOS and uses thereof
    Patent number: 9975950
    Abstract: The present invention provides antibodies directed against ICOS or a derivative thereof which neutralize ICOS engagement on Treg by inhibiting the fixation between ICOS and ICOS-L and abrogate proliferation of Treg induced by plasmacytoid dendritic cells. The present invention further provides antibodies directed against ICOS or a derivative thereof which induce IL-10 and IFN? production, induce CD4+ T cells proliferation, reduce Tconv proliferation, and increase the immunosuppressive function of Treg.
    Type: Grant
    Filed: April 20, 2017
    Date of Patent: May 22, 2018
    Assignees: INSERM (INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE), INSTITUT JEAN PAOLI & IRENE CALMETTES, UNIVERSITE D'AIX-MARSEILLE, Universite Claude Bernard—Lyon 1, Centre Leon Berard
    Inventors: Julien Faget, Christophe Caux, Christine Menetrier-Caux, Jacques Nunes, Daniel Olive
  • Method for randomly texturing a semiconductor substrate
    Patent number: 9941445
    Abstract: The invention relates to a method for texturing a semiconductor substrate (1), comprising steps consisting in forming a plurality of cavities of random shapes, depths and distribution, in an etch mask (2), by means of non-homogeneous reactive-ion etching, forming a first rough random design, and etching the substrate using the etch mask, by means of reactive-ion etching, in such a way as to transfer the first rough random design into the substrate and to produce a second rough random design (200), comprising cavities (20) of random shapes, depths (d2r) and distribution, on the surface of the substrate.
    Type: Grant
    Filed: June 2, 2015
    Date of Patent: April 10, 2018
    Assignees: UNIVERSITÉ D'AIX-MARSEILLE, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE, THALES
    Inventors: Ludovic Escoubas, Gerard Jean Louis Berginc, Jean-Jacques Simon, Vincent Brissonneau
  • BLOOD FLOW REDUCER AND METHOD USING THE SAME
    Publication number: 20180085127
    Abstract: A blood flow reducer (20) for insertion in a blood vessel, the reducer (20) being adapted to be deformed from a first configuration to an expanded configuration, wherein, in the expanded configuration, the reducer (20) defines an axial lumen (40) for allowing blood flow therethrough, the axial lumen (40) having a smallest cross-section, the reducer (20) has a largest cross-section, and the smallest cross-section is comprised between 20% and 90% of the largest cross-section. In particular, the smallest cross-section is strictly comprised between 70% and 90% of the largest cross-section. A method for preconditioning a liver of a living being before partial hepatectomy, wherein a 10 to 30% stenosis is created in a branch of a portal vein conducting blood to a first liver lobe.
    Type: Application
    Filed: March 20, 2015
    Publication date: March 29, 2018
    Applicants: Université d'Aix-Marseille, ASSISTANCE PUBLIQUE - HÔPITAUX DE MARSEILLE, INSTITUT NATIONAL DE LA SANTÉ ET DE LA RECHERCHE MÉDICALE
    Inventors: Pierre Henri Rolland, Vincent Vidal, Emilie Hélène Marie Grégoire
  • Device and method for detecting radiation particles
    Patent number: 9921317
    Abstract: A device for detecting radiation particles comprising at least one sensor for sensing radiation particles, capable of supplying an electrical pulse when it is traversed by at least one radiation particle, and at least one detection circuit comprising a voltage-controlled oscillator to which said electrical pulse originating from the sensor is supplied as the control voltage. The voltage-controlled oscillator is a ring oscillator.
    Type: Grant
    Filed: March 11, 2015
    Date of Patent: March 20, 2018
    Assignees: UNIVERSITÉ D'AIX MARSEILLE, CENTRE NAITONAL DE LA RECHERCHE SCIENTIFIQUE, UNIVERSITÉ D'AVIGNON
    Inventors: Wenceslas Rahajandraibe, Hassen Aziza, Karine Castellani-Coulie, Gilles Micolau