Patents Assigned to Universite dé Lorraine
  • Publication number: 20220338784
    Abstract: Systems and methods are disclosed for visualizing reentrant circuits in the heart via pseudo-activation maps. Techniques disclosed comprise receiving sets of ECG data and respective pacing sites. Each of the sets is generated by pacing heart tissue at a respective site of the pacing sites. Techniques disclosed further comprise computing correlation gradients representative of morphological changes across sets, of the sets of the ECG data, of respective neighboring sites of the pacing sites. Based on the computed correlation gradients, a core zone associated with a reentrant circuit is identified. Then, relative to the identified core zone, one or more pseudo-activation maps are generated.
    Type: Application
    Filed: April 19, 2022
    Publication date: October 27, 2022
    Applicants: Johnson & Johnson Medical SAS, L'Université de Lorraine, The Centre Hospitalier Regional Universitaire de Nancy
    Inventors: Philip Hoyland, Freddy Odille, Christian de CHILLOU de CHURET
  • Patent number: 11404761
    Abstract: A method for depositing an electrically conductive metal onto at least one portion of the inner surface (3) of an internal cavity (2) of a waveguide (1) includes: preparing a suspension containing at least one liquid and at least one precursor of the electrically conductive metal in suspension in said at least one liquid; coating at least one portion of the inner surface (3) of the internal cavity (2) of the waveguide (1) with the suspension, and heat-treating at least said portion of the inner surface (3) of the internal cavity (2) of the waveguide (1) coated with the suspension. A method for manufacturing a metallized waveguide can implement this deposition method.
    Type: Grant
    Filed: July 31, 2020
    Date of Patent: August 2, 2022
    Assignees: AML FINANCES, UNIVERSITE DE LORRAINE
    Inventors: Jean-Yves Milojevic, Régis Limbach, Léo Portebois, Nicolas Ramenatte, Thierry Mazet
  • Publication number: 20220236432
    Abstract: A device for radioactivity counting and characterization for a solution. The device includes a container having at least two recesses, a first recess for receiving a vial and a second recess for receiving a radioactivity sensor, a radioactivity sensor having a semiconductor sensor presenting a cone of detection directed to the first recess of the container for receiving a vial, a removable closure element, an armored cover around the container and its upper face, the upper face of the armored cover having an opening for introducing the vial into the container and a plate for supporting the device.
    Type: Application
    Filed: June 18, 2020
    Publication date: July 28, 2022
    Applicant: UNIVERSITÉ DE LORRAINE
    Inventors: Guénolé MATHIAS-LAOT, Quentin THOMAS
  • Publication number: 20220162537
    Abstract: A fluidic system for loading a therapeutic or imaging agent into the lumen of extracellular vesicles from producer cells, including at least one container, a liquid medium contained in the container, producer cells, a liquid medium stirrer and a device for controlling the speed of the stirrer suitable for the growth of the producer cells, wherein it also includes a device for controlling the speed of the stirrer and the stirrer, of which the shape and dimensions of the container are suitable for generating a turbulent flow of the liquid medium in the container for exerting shear stresses on the producer cells in order to carry out the loading of a therapeutic or imaging agent into the lumen of the extracellular vesicles produced simultaneously by the fluidic system.
    Type: Application
    Filed: December 27, 2019
    Publication date: May 26, 2022
    Applicants: CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE, UNIVERSITÉ DE LORRAINE, UNIVERSITE DE PARIS
    Inventors: Iris MARANGON, Marie MILLARD, Lina BOLOTINE, Amanda SILVA, Alice GRANGIER, Florence GAZEAU, Claire WILHELM, Max PIFFOUX
  • Publication number: 20220064076
    Abstract: The present invention relates to the field of crop fertilization, and particularly to a biofertilizing bacterial strain. In particular, the present invention relates to the bacterial strain deposited on Oct. 24, 2018, at the Collection Nationale de Culture de Microorganismes (CNCM), 28 rue du Dr. Roux, 75724 PARIS CEDEX 15, under the Budapest Treaty under number CNCM I-5372, and to the uses of this strain. The invention also relates to a composition comprising the above-mentioned bacterial strain and to a fertilization process comprising the application of this composition to a plant or to a soil.
    Type: Application
    Filed: December 19, 2019
    Publication date: March 3, 2022
    Applicants: Université de Lorraine, Institut National de la Recherche Agronomique
    Inventors: Sophie SLEZACK - DESCHAUMES, Séverine PIUTTI, Pierre L'YVONNET, Sandro ROSELLI
  • Publication number: 20220055960
    Abstract: The present invention relates to the field of crop fertilization, and particularly to a biofertilizing bacterial strain. In particular, the present invention relates to the bacterial strain deposited on Oct. 24, 2018, at the Collection Nationale de Culture de Microorganismes (CNCM), 28 rue du Dr. Roux, 75724 PARIS CEDEX 15, under the Budapest Treaty under number CNCM I-5373, and to the uses of this strain. The invention also relates to a composition comprising the above-mentioned bacterial strain and to a fertilization process comprising the application of this composition to a plant or to a soil.
    Type: Application
    Filed: December 19, 2019
    Publication date: February 24, 2022
    Applicants: Université de Lorraine, Institut National de la Recherche Agronomique
    Inventors: Sophie SLEZACK - DESCHAUMES, Séverine PIUTTI, Pierre L'YVONNET, Sandro ROSELLI
  • Publication number: 20220044834
    Abstract: The present invention relates to a process for treating aqueous effluents from the primary circuit of a nuclear power plant implementing a separation of boric acid using a reverse osmosis membrane, characterized by the fact that it comprises steps consisting of treating the effluents using a multi-stage assembly composed of reverse osmosis modules comprising a membrane with a high boron rejection rate, arranged in parallel and in series, and recycling of the intermediate products to different points in the assembly.
    Type: Application
    Filed: December 4, 2019
    Publication date: February 10, 2022
    Applicants: Electricite de France, Centre National de la Recherche Scientifique (CNRS), Universite de Lorraine
    Inventors: Thibaut Neveux, Eve Bailleul, Christophe Castel, Eric Favre
  • Publication number: 20210117883
    Abstract: A method for process analysis, where the process includes at least one succession of steps associated to objectives to be achieved to obtain the target objective. The steps include receiving a process map, receiving a progression value of each node of the process map and the state of each node of the process map, updating the process map for each node.
    Type: Application
    Filed: October 17, 2019
    Publication date: April 22, 2021
    Applicant: UNIVERSITÉ DE LORRAINE
    Inventors: Corentin KERBIRIOU, Henri REYDON, Jeffrey HONION, Laurie PACINI
  • Patent number: 10951119
    Abstract: To this end, the invention relates to a method for controlling a switched electronic circuit connecting an electrical voltage source u to a load R and forming a system having an output y and a plurality of operating modes i, at least some of which thus can be activated by following a switching rule o. According to the invention, the following steps are provided: —measuring state variables x of the system having equilibrium values xr; —introducing at least one parameter p into the system, representing a measuring error of an electrical unknown of the operation of the circuit; —estimating the parameter from a state monitor and applying a Lyapunov function thereto; —deducing therefrom the equilibrium values of the system in order to obtain the control rule.
    Type: Grant
    Filed: May 22, 2018
    Date of Patent: March 16, 2021
    Assignees: SAFRAN ELECTRONICS & DEFENSE, UNIVERSITE DE LORRAINE
    Inventors: Gaetan Beneux, Jamal Daafouz, Louis Grimaud, Pierre Riedinger
  • Patent number: 10948498
    Abstract: A cardiovascular event or disease is prevented or treated in a subject by measuring the expression level of soluble Triggering Receptors Expressed on Myeloid cells-1 (sTREM-1) level in a sample from the subject and comparing it to a reference level. Based on this comparison, subjects that are at risk of having or developing a cardiovascular event or disease are identified, and administered a suitable therapy.
    Type: Grant
    Filed: August 8, 2014
    Date of Patent: March 16, 2021
    Assignees: INOTREM, APHP (Assistance Publique-Hôpitaux de Paris), INSERM (Institut National de la Santé et de la Recherche Médicale), Université de Lorraine
    Inventors: Marc Derive, Sebastien Gibot, Hafid Ait-Oufella, Amir Boufenzer, Tabasomme Simon, Nicolas Danchin
  • Publication number: 20210036397
    Abstract: A method for depositing an electrically conductive metal onto at least one portion of the inner surface (3) of an internal cavity (2) of a waveguide (1) includes: preparing a suspension containing at least one liquid and at least one precursor of the electrically conductive metal in suspension in said at least one liquid; coating at least one portion of the inner surface (3) of the internal cavity (2) of the waveguide (1) with the suspension, and heat-treating at least said portion of the inner surface (3) of the internal cavity (2) of the waveguide (1) coated with the suspension. A method for manufacturing a metallized waveguide can implement this deposition method.
    Type: Application
    Filed: July 31, 2020
    Publication date: February 4, 2021
    Applicants: AML FINANCES, UNIVERSITE DE LORRAINE
    Inventors: Jean-Yves Milojevic, Régis Limbach, Léo Portebois, Nicolas Ramenatte, Thierry Mazet
  • Patent number: 10895503
    Abstract: A bimodal optical spectroscopy device for producing spectra of autofluorescence and diffuse reflectance signals from a biological sample such as skin.
    Type: Grant
    Filed: November 30, 2016
    Date of Patent: January 19, 2021
    Assignees: UNIVERSITE DE LORRAINE, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE
    Inventors: Marine Amouroux, Walter Blondel, Alain Delconte
  • Patent number: 10891728
    Abstract: A method is provided for identifying an isthmus in a three-dimensional map of a cardiac cavity by means of a processing unit configured to perform the following steps: a) correlation between a set of stimulated points of the cardiac cavity, each stimulated point being represented by a set of signals that are obtained following surface electrocardiography (ECG), excluding ventricular tachycardia; b) identification of a watershed line on the basis of the above correlation results and of the 3D coordinates of the stimulated points in the 3D map; and c) determination of the isthmus based on a 3D corridor substantially transverse to the watershed line.
    Type: Grant
    Filed: April 1, 2016
    Date of Patent: January 12, 2021
    Assignees: UNIVERSITE DE LORRAINE, CENTRE HOSPITALIER REGIONAL DE NANCY
    Inventor: Christian De Chillou
  • Publication number: 20200397018
    Abstract: A process for producing a protein isolate from an oilseed meal, and the isolate thus obtained, said isolate comprising proteins and an amount of 4 wt. % or less of phytic acid, said amount of phytic acid being by weight of proteins in said isolate. The process may comprise the following steps: a) providing an oilseed meal; b) mixing the oilseed meal with a first aqueous solvent to form a slurry at a pH ranging from 6 to 7.8, said slurry having a solid phase; c) separating said solid phase from said slurry, d) mixing said separated solid phase with a second aqueous solvent at a pH ranging from 1 to 3.
    Type: Application
    Filed: November 14, 2018
    Publication date: December 24, 2020
    Applicants: Avril, Universite de Lorraine, Centre National de la Recherche Scientifique
    Inventors: Claire DEFAIX, Romain KAPEL, Olivier GALET
  • Patent number: 10854807
    Abstract: Some embodiments are directed to a piezoelectric sensor, including a body with a central cavity; and a membrane extending over the cavity, which membrane is fastened to the body via its periphery and includes a carrier layer made of polymer and a sensitive layer made of piezoelectric polymer, the membrane being able to deform or vibrate. The sensitive layer is made of a material including a polymer filled with inorganic nanomaterials. Instrument including such a sensor.
    Type: Grant
    Filed: March 24, 2016
    Date of Patent: December 1, 2020
    Assignee: UNIVERSITÉ DE LORRAINE
    Inventors: Didier Rouxel, Brice Vincent, Laurent Badie
  • Patent number: 10844459
    Abstract: A method for extracting the tantalum from an acid aqueous phase A1 comprising at least one step comprising the bringing of the aqueous phase A1 into contact with a phase A2 not miscible with water, and then the separation of the aqueous phase A1 from the phase A2, the phase A2 consisting of one ionic liquid or a mixture of ionic liquids as an extractant. A method for recovering the tantalum that implements this extraction method and to a use of an ionic liquid or of a mixture of ionic liquids as an extractant, in order to extract the tantalum from such an aqueous phase A1.
    Type: Grant
    Filed: August 10, 2016
    Date of Patent: November 24, 2020
    Assignees: CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE, UNIVERSITE DE MONTPELLIER, UNIVERSITE DE CHAMBERY, ECOLE NATIONALE SUPERIEURE DE CHIMIE DE MONTPELLIER, TND, UNIVERSITE DE LORRAINE
    Inventors: Raphael Turgis, Guilhem Arrachart, Stéphane Pellet-Rostaing, Micheline Draye, Sophie Legeai, David Virieux, Christian Thomas
  • Patent number: 10751947
    Abstract: An additive manufacturing device processes voxels representing an object to be additively manufactured by determining two graphs depending on whether the voxels indicate full or empty spaces, and redefines some of the voxels indicating an empty space as full spaces in order to ensure mechanical stability.
    Type: Grant
    Filed: June 28, 2016
    Date of Patent: August 25, 2020
    Assignees: Inria Institut National De Recherche En Informatique et en automatique, Universite De Lorraine
    Inventors: Sylvain Lefebvre, Jeremie Dumas, An Lu
  • Patent number: 10755828
    Abstract: A device for preparing radioactive solutions, in particular radiopharmaceutical solutions, including: a movable support block with at least two cells capable of accommodating a vial; and a shielded covering, including a side wall surrounding the periphery of the support block and an upper wall covering the upper face of the support block, an opening being provided in the upper wall of the covering. A means for driving the support block is configured to selectively displace the support block into positions, referred to as working positions, in which a given cell is aligned with the opening to allow access to the cell from the outside of the covering. The support block is configured such that it can be further brought to a position, referred to as closing position, in which the opening is sealed by a shielded element carried by the support block.
    Type: Grant
    Filed: December 5, 2017
    Date of Patent: August 25, 2020
    Assignee: UNIVERSITE DE LORRAINE
    Inventors: Guénolé Mathias-Laot, Quentin Thomas
  • Patent number: 10658561
    Abstract: A thermoelectric element, particularly for a thermoelectric converter, includes an assembly of constituent layers comprising a central layer made of p- or n-type thermoelectric material, then, in an assembly direction, and on each side of said central layer, an intermediate layer forming a diffusion barrier followed by a buffer layer made of composite metal material. The buffer layers are intended to be secured to metal electrodes, characterized in that the cumulative thickness of the two buffer layers is greater than or equal to 50% of the thickness of the central layer, and preferably greater than or equal to 100% of the thickness of the central layer and very preferably greater than or equal to 200% of the thickness of the central layer, and in that the constituent material of the buffer layers is an alloy of two metals chosen from the family: TixAg1-x, VxFe1-x, VxAg1-x, TixFe1-x, where 0<x<1.
    Type: Grant
    Filed: August 18, 2016
    Date of Patent: May 19, 2020
    Assignees: UNIVERSITE DE LORRAINE, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS)
    Inventors: Alexandre Jacquot, Bertrand Lenoir, Eugen Geczi, Iurii Kogut, Driss Kenfaui, Philippe Masschelein
  • Patent number: 10619494
    Abstract: A part include a refractory alloy including a niobium matrix having metal silicide inclusions present therein, the surface of the part being coated by a protective coating, the protective coating including a phase having the following stoichiometry: (NbxTi1-x)3M?Cr?Si?X? where M designates Fe, Co, or Ni, X designates one or more other elements that might be present, x lies in the range 0 to 1, x lies in the range 5 to 8.5, and the sum ?+? lies in the range 3 to 7; or Nb4M??Si?X??? where M? designates Fe, Co, or Ni, X? designates one or more other elements that might be present, ? lies in the range 3.2 to 4.8, and ? lies in the range 6 to 8.
    Type: Grant
    Filed: May 21, 2018
    Date of Patent: April 14, 2020
    Assignees: SAFRAN AIRCRAFT ENGINES, UNIVERSITE DE LORRAINE
    Inventors: Stéphane Knittel, Stéphane Mathieu, Michel Vilasi