Patents Assigned to Universite dé Lorraine
  • Patent number: 10603357
    Abstract: A polypeptide comprising one or more sequences derived from CDR2 or CDR3 of a TREM-1 protein, characterised by the ability to treat, ameliorate, or lessen the symptoms of conditions including sepsis, septic shock or sepsis-like conditions and IBD.
    Type: Grant
    Filed: December 14, 2015
    Date of Patent: March 31, 2020
    Assignees: Bristol-Myers Squibb Company, Universite de Lorraine
    Inventors: Gilbert Faure, Sebastien Gibot, Paola Panina, Nadia Passini
  • Patent number: 10548494
    Abstract: A method is provided for determining a personalized cardiac model, including steps of (i) computing a velocity time profile of a blood flow across a selected area of the heart or the aorta during at least one cardiac cycle, using data acquired with a Magnetic Resonance Imaging (MRI) device; (ii) performing a segmentation of the velocity time profile so as to identify cardiac phases according to a predefined generic cardiac model; and (iii) computing normalized time location and/or duration of the cardiac phases within cardiac cycles so as to define a personalized cardiac model.
    Type: Grant
    Filed: January 7, 2014
    Date of Patent: February 4, 2020
    Assignees: UNIVERSITE DE LORRAINE, CENTRE HOSPITALIER REGIONAL DE NANCY
    Inventors: Christophe Meyer, Pierre-André Vuissoz, Laurent Bonnemains, Jacques Felblinger
  • Publication number: 20200011572
    Abstract: Thermoregulated multilayer material characterized in that it comprises at least one substrate and one thermoregulated layer, said thermoregulated multilayer material having: for ? radiation of between 0.25 and 2 ?m, an absorption coefficient ?m?0.8; and, for incident ? radiation of between 7.5 and 10 ?m, a reflection coefficient ?m: ?m?0.85, when the temperature T of said multilayer material 1 is ?100° C.; ?m between 0.3 and 0.85, when the temperature T of said multilayer material is between 0 and 400° C.
    Type: Application
    Filed: March 12, 2018
    Publication date: January 9, 2020
    Applicants: VIESSMANN FAULQUEMONT, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE, UNIVERSITÉ DE LORRAINE
    Inventors: David Mercs, Fabien Capon, Nicolas Portha, Alexis Boileau
  • Publication number: 20200000856
    Abstract: The disclosure relates to human mesenchymal stem cells from Wharton's jelly, a method for preparing them, and the therapeutic uses thereof, in particular for the treatment of sepsis and specifically septic shock. The treatment may involve the administration to a subject in need thereof a pharmaceutical composition including the human mesenchymal stem cells from Wharton's jelly and a pharmaceutically acceptable excipient.
    Type: Application
    Filed: February 28, 2018
    Publication date: January 2, 2020
    Applicants: UNIVERSITÉ DE LORRAINE, CENTRE HOSPITALIER RÉGIONAL UNIVERSITAIRE DE NANCY
    Inventors: Danièle BENSOUSSAN, Sébastien GIBOT, Loïc REPPEL, Caroline LAROYE, Amir BOUFENZER, Léonore AVERCENC, Céline HUSELSTEIN
  • Patent number: 10510177
    Abstract: A data processing device applies pattern data to surface data on the basis of projection data, subdividing the surface data into voxels and determining the optimum projection data for each voxel according to its surroundings.
    Type: Grant
    Filed: June 28, 2016
    Date of Patent: December 17, 2019
    Assignees: Inria Institute National De Recherche En Informatique Et En Automatique, Universite De Lorraine
    Inventors: Sylvain Lefebvre, Jeremie Dumas, An Lu
  • Patent number: 10351945
    Abstract: The method for obtaining a nano-capsule structure includes at least one layer of resin deposited on a layer of substrate. The capsule nanometric in size is capable of enabling the encapsulation of a compound. The layer of resin is structured, by low voltage electron lithography, or by optical lithography or by nanoimprinting in such a way as to obtain at least one cavity in the thickness of the layer of resin. The cavity has a depth smaller than the thickness of the layer of resin. At least one layer of an encapsulating material is isotropically deposited by sputtering the material under vacuum. The cavity is sealed with a sealing material. The layer of resin is dissolved by soaking in a suitable solvent.
    Type: Grant
    Filed: June 13, 2013
    Date of Patent: July 16, 2019
    Assignees: UNIVERSITE DE LORRAINE, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE
    Inventors: Stefan McMurtry, Omar Elmazria
  • Patent number: 10339698
    Abstract: A method for discriminating and identifying, by 3D imaging, an object in a complex scene comprises the following steps: generating a sequence of 2D MIP images of the object, from a 3D voxel volume of the complex scene, this volume visualized by an operator by using an iterative process of MIP type from a projection plane and an intensity threshold determined by the operator on each iteration, automatically extracting, from the sequence of images, coordinates of a reduced volume corresponding to the sequence of images, choosing one of the intensity thresholds used during the iterations, automatically extracting, from the 3D volume of the complex scene, from the coordinates and chosen intensity threshold, a reduced 3D volume containing the object, automatically generating, from the reduced volume, by intensity threshold optimization, an optimized intensity threshold and an optimized voxel volume, a color being associated with each intensity, identifying the object by visualization.
    Type: Grant
    Filed: December 17, 2015
    Date of Patent: July 2, 2019
    Assignees: THALES, UNIVERSITE DE LORRAINE, SISPIA
    Inventors: Stefan Berechet, Ion Berechet, Jean-Baptiste Bellet, Gérard Berginc
  • Patent number: 10316224
    Abstract: A composition based on phenolic resin comprising at least one phenolic resin, a vegetable protein hydrolysate, preferentially a wheat gluten hydrolysate, and an agent for accelerating curing, and also to the process for the production thereof.
    Type: Grant
    Filed: October 7, 2014
    Date of Patent: June 11, 2019
    Assignees: TEREOS STARCH AND SWEETENERS BELGIUM, UNIVERSITE DE LORRAINE
    Inventors: Antonio Pizzi, Marie-Christine Lagel, Andreas Redl
  • Patent number: 10290138
    Abstract: Device comprising a memory (2) storing sound data, three-dimensional surface data, and a plurality of control data sets which represent control points defined by data of coordinates which are associated with sound data, and a processor (4) which, on the basis of first and second successive sound data, and of first three-dimensional surface data, selects the control data sets associated with the first and second sound data, and defines second three-dimensional surface data by applying a displacement to each point. The displacement of a given point is calculated as the sum of displacement vectors calculated for each control point on the basis of the sum of first and second vectors, weighted by the ratio between the result of a function with two variables exhibiting a zero limit at infinity applied to the given point and to the control point and the sum of the result of this function applied to the point on the one hand and to each of the control points on the other hand.
    Type: Grant
    Filed: March 10, 2016
    Date of Patent: May 14, 2019
    Assignee: UNIVERSITE DE LORRAINE
    Inventors: Slim Ouni, Guillaume Gris
  • Patent number: 10227684
    Abstract: Process for depositing a coating on a substrate having at least one cavity, comprising a step of mixing ground powders of an activating agent and a powder of the metal or of the alloy to be deposited on the substrate that were ground in step a) and a liquid so as to form a suspension, and a step of applying the suspension to the portion of the substrate to be coated.
    Type: Grant
    Filed: February 4, 2014
    Date of Patent: March 12, 2019
    Assignees: L'Air Liquide Societe Anonyme Pour L'Etude Et L'Exploitation Des Procedes Georges Claude, Centre National De La Recherche Scientifique, Universite De Lorraine
    Inventors: Nicolas Richet, Thierry Mazet, Michel Vilasi, Stephane Mathieu
  • Patent number: 10211618
    Abstract: A method and a circuit for detecting an electric arc in an electric circuit supplied with AC current during a supply period includes measuring at least one input signal (S) among a current (I) and an input voltage (U) of the electric circuit, supplying a warning signal (A1) to indicate that an electric arc occurs when the input signal (S) is constant over at least one portion of the supply period, digitally sampling the input signal (S) during the measurement thereof according to predetermined levels and, to identify that the input signal (S) is constant, determining the frequency at which each level is reached by the input signal (S) over a predetermined time window, comparing the frequency of each level with a predetermined warning threshold, and issuing the warning signal if the frequency of at least one of the levels is higher than the warning threshold.
    Type: Grant
    Filed: February 3, 2015
    Date of Patent: February 19, 2019
    Assignees: LEACH INTERNATIONAL EUROPE SA, UNIVERSITE DE LORRAINE
    Inventors: Jonathan Andrea, Patrick Schweitzer, Serge Weber, Etienne Tisserand, Marc Bournat
  • Patent number: 10167468
    Abstract: The present invention relates to methods and pharmaceutical compositions for the treatment of cardiovascular fibrosis. In particular, the present invention relates to an inhibitor of Neutrophil Gelatinase-Associated Lipocalin (NGAL) activity or expression for use in a method for treating or preventing cardiovascular fibrosis in a subject in need thereof.
    Type: Grant
    Filed: January 31, 2017
    Date of Patent: January 1, 2019
    Assignees: INSERM (INSTITUT NATIONAL DE LA SANTÉ ET DE LA RECHERCHE MÉDICALE), UNIVERSITE DE LORRAINE, CENTRE HOSPITALIER ET UNIVERSITAIRE DE NANCY (CHU), UNIVERSITE PARIS DIDEROT-PARIS 7, UNIVERSITE PARIS DESCARTES
    Inventors: Frederic Jaisser, Nicolette Farman, Antoine Tarjus, Patrick Rossignol, Faiez Zannad
  • Patent number: 10128652
    Abstract: A method of stabilizing a DC electricity network, the network including a DC voltage source powering electrical loads that are connected in parallel to terminals of the voltage source and each of which is to receive a current or voltage setpoint. The method stabilizes the network by regulating setpoints applied to the loads by a virtual stabilization impedance generated at terminals of each load, the virtual impedances being dimensioned to stabilize the network in desired operating points and in given configurations of the network including a state in which at least one load is inactive or has failed and a state in which the stabilization of a load is inactive. Each virtual impedance is generated by a non-linear regulation loop acting on the setpoint for the corresponding load.
    Type: Grant
    Filed: September 12, 2012
    Date of Patent: November 13, 2018
    Assignees: LABINAL POWER SYSTEMS, UNIVERSITE DE LORRAINE
    Inventors: Sebastien Vieillard, Pierre Magne, Farid Meibody-Tabar, Babak Nahid-Mobarakeh, Serge Pierfederici
  • Patent number: 10053780
    Abstract: Process for depositing a corrosion-protection coating on at least one portion of the surfaces of a metallic substrate having at least one cavity with an equivalent diameter emm<2 mm and a length/width ratio of greater than 150, using an aqueous suspension comprising powder of the metal to be deposited on the substrate combined with an agent for protecting the surface of the metal powder, a diluent, and at least one additive, the particles of the suspension each having an equivalent diameter d such that d?emm/10.
    Type: Grant
    Filed: September 17, 2014
    Date of Patent: August 21, 2018
    Assignees: L'Air Liquide, Société Anonyme pour l'Etude et l'Exploitation des Procédés Georges Claude, Centre National de la Recherche Scientifique, Université de Lorraine, Université de Limoges
    Inventors: Thierry Chartier, Pascal Del-Gallo, Sebastien Doublet, Thierry Mazet, Laurent Prost, Nicolas Ramenatte, Fabrice Rossignol, Michel Vilasi
  • Patent number: 10035122
    Abstract: A heat insulation material is provided that is produced by drying a fibrous matrix impregnated with a solution of pseudo-peptides of formula (I), wherein: R is a side-chain of a natural or synthetic amino acid, R1 is either a linear or branched (C1-C3)alkyl group, or a linear or branched (C1-C3)alcoxy group, or an aryl group, or an aryl(C1-C3)alkyl group, or an aryloxy group, or a saturated or unsaturated heterocycle, n=1 or 2, and A is an aromatic or heteroaromatic group with at least one cycle.
    Type: Grant
    Filed: August 28, 2015
    Date of Patent: July 31, 2018
    Assignees: UNIVERSITE DE LORRAINE, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE
    Inventors: Brigitte Jamart, Alain Degiovanni, Sébastien Son, Yves Jannot, Guillaume Pickaert
  • Publication number: 20180162058
    Abstract: A method for determining a set of points to be supported for an object to be manufactured by means of an additive manufacturing method, characterised in that it comprises a step consisting of subdividing the object into successive layers, each layer corresponding to a thickness of material deposited during the manufacture of the object; and, for each layer, adding, to a set of points to be supported, points to be supported (PS) on the surface of the object that make it possible to ensure the stability of all of the sub-objects (2n), a sub-object being defined as a solid resulting from the manufacture of the i first layers (Ci) of the object.
    Type: Application
    Filed: June 2, 2015
    Publication date: June 14, 2018
    Applicants: INRIA INSTITUT NATIONAL DE RECHERCHE EN INFORMATIQUE ET EN AUTOMATIQUE, UNIVERSITE DE LORRAINE
    Inventors: SYLVAIN LEFEBVRE, JEREMIE DUMAS, JEAN HERGEL
  • Patent number: 9994690
    Abstract: A method for producing polyHIPE porous monoliths, of the polyHIPE type or in the form of a rigid foam, by hardening solutions of condensed tannins in the presence of oil and/or air or in the presence of a non-water-miscible volatile solvent and/or air. Also disclosed is the use of these materials in the areas of catalysis, chromatography, heat and sound insulation, tissue engineering and medication release and as a floral foam.
    Type: Grant
    Filed: August 27, 2013
    Date of Patent: June 12, 2018
    Assignees: UNIVERSITE DE LORRAINE, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE
    Inventors: Alain Celzard, Andrzej Szczurek, Vanessa Fierro, Antonio Pizzi
  • Patent number: 9995153
    Abstract: A method for manufacturing a part coated with a protective coating includes: forming a protective coating across all or part of the surface of a part, wherein the part includes a refractory alloy including a niobium matrix containing metal silicide inclusions, wherein the protective coating is formed by a pack carburization method from a cement including: i. a mixture A of (NbxTi1-x)3M3CrSi6 and M0.6Cr0.4Si where M denotes Fe, Co or Ni and x is between 0 and 1, or ii. a mixture B of M?Si, NbSi2 and Nb4M?4Si7 where M? denotes Fe, Co or Ni.
    Type: Grant
    Filed: December 1, 2015
    Date of Patent: June 12, 2018
    Assignees: SAFRAN AIRCRAFT ENGINES, UNIVERSITE DE LORRAINE
    Inventors: Stéphane Knittel, Stéphane Mathieu, Michel Vilasi
  • Patent number: 9925495
    Abstract: An electrolyte-separating membrane includes a carrier made of a porous and permeable synthetic thermoplastic material that is larger than 0.8 mm in thickness and an active layer made of a material able to induce insertion and deinsertion reactions for selective transfer of cations through the membrane. The active layer is deposited on the carrier and is hermetic. The material of the active layer may in particular be a molybdenum cluster chalcogenide. The invention aims to provide an electrolyte-separating membrane that is able to transfer cations selectively and that may be manufactured with large dimensions. The invention also relates to a cation transfer method employing this membrane and to a process for manufacturing said membrane, in particular by selective laser sintering of a powdered polymer.
    Type: Grant
    Filed: February 5, 2014
    Date of Patent: March 27, 2018
    Assignees: CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE, UNIVERSITE DE LORRAINE
    Inventors: Jean-Marie Lecuire, Samuel Philippe Claude Kenzari, Elodie Guyot, Sébastien Diliberto
  • Patent number: 9915484
    Abstract: Process for producing an element comprising a multilayer architecture, the layers of which comprise primary channels on their upper faces, said process comprising the following successive steps: (a) producing secondary channels on the lower faces of each layer, each secondary channel being intended to be facing a primary channel of the neighboring lower layer within the architecture, (b) depositing a coating that protects against oxidation at a temperature of between 500° C. and 1000° C. and against corrosion over all of the lower and upper surfaces of the layers, (c) sanding or mechanical cleaning of the surfaces intended to be assembled, and (d) assembling via superposition of the various layers so that each secondary channel of a lower face of an upper layer is facing and is centered on a primary channel of the neighboring lower layer, the width of each secondary channel being greater than the width of the primary channel which it is facing within the architecture.
    Type: Grant
    Filed: March 17, 2014
    Date of Patent: March 13, 2018
    Assignees: L'AIR LIQUIDE SOCIÉTÉ ANONYME POUR L'ÉTUDE ET L'EXPLOITATION DES PROCEDES GEORGES CLAUDE, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE, UNIVERSITE DE LORRAINE
    Inventors: Damien Sallais, Laurent Prost, Pascal Del-Gallo, Marc Wagner, Michel Vilasi, Thierry Mazet, Stephane Mathieu