Abstract: A support structure for supporting an object during the manufacture of same by means of an additive manufacturing method; method for generating such a structure.
Type:
Application
Filed:
June 2, 2015
Publication date:
March 8, 2018
Applicants:
INRIA INSTITUT NATIONAL DE RECHERCHE EN INFORMATIQUE ET EN AUTOMATIQUE, UNIVERSITE DE LORRAINE
Inventors:
SYLVAIN LEFEBVRE, JEREMIE DUMAS, JEAN HERGEL
Abstract: The present invention relates to polypeptides fragments derived from the protein TLT-1 and their uses for the treatment of inflammatory conditions and more particularly for the treatment of sepsis.
Type:
Grant
Filed:
April 29, 2015
Date of Patent:
November 14, 2017
Assignees:
Institut National de la Sante et de la Recherche Medicale (INSERM), UNIVERSITE DE LORRAINE
Abstract: For passive sensor with resonator having a natural frequency, a method comprises: a first phase emission of an electromagnetic signal toward the passive sensor at an emission frequency, the resonator oscillating in a forced regime at the emission frequency and then oscillating at its natural frequency when the emission is cut off; a first phase reception of the damped signal oscillating at natural frequency emitted by passive sensor, a measurement of the frequency being performed; a second phase emission of an electromagnetic signal at the measured frequency toward the passive sensor, the resonator oscillating in a forced regime at the measured frequency and then oscillating at its natural frequency when the emission is cut off; a second phase reception of the damped signal oscillating at natural frequency, a measurement of the frequency being performed, determination of the natural frequency being stopped due to measurement performed in this second reception phase.
Type:
Grant
Filed:
October 19, 2012
Date of Patent:
October 10, 2017
Assignees:
Universite de Lorraine, Centre National de la Recherche Scientifique
Inventors:
Mohamed M'Jahed, Gerard Prieur, Omar El Mazria
Abstract: A method for transcribing an odor or an aroma into a colorimetric description comprises: physico-chemical analysis of said odor or of said aroma in order to associate with it a physico-chemical description comprising a physico-chemical vector, comprising proportions associated with a predetermined set of respective volatile molecules; physico-chemical analysis of a set of so-called test odors and/or aromas in order to assign to each test odor or aroma of said set a so-called test physico-chemical description comprising a so-called test physico-chemical vector comprising test proportions associated with said predetermined set of respective volatile molecules; assigning to the test odors and/or aromas respective test colorimetric descriptions comprising so-called test proportions associated with a set of respective colors; assigning to the odor or to the aroma a colorimetric description comprising proportions associated with said respective colors.
Abstract: A flotation process for recovering feldspar from a feldspar containing feed material is disclosed. The process includes forming an aqueous suspension of a feldspar containing feed material, in the absence of hydrofluoric acid, wherein the suspension includes from 0.004 to 0.3% wt. of a flotation reagent including: (a) one or more amines, containing at least one aliphatic hydrocarbon chain, linear or branched, saturated or unsaturated, including 8 to 50 carbon atoms, or a salt thereof; and (b) one or more primary, secondary or tertiary alcohols, containing at least one aliphatic hydrocarbon chain, linear or branched, saturated or unsaturated, including 8 to 50 carbon atoms; the ratio of (a) to (b) ranging from 500:1 to 1:40 by weight. The process further includes agitating the obtained suspension to produce a feldspar containing fraction, and separating the feldspar containing fraction.
Type:
Grant
Filed:
January 6, 2011
Date of Patent:
June 13, 2017
Assignees:
Imerys Ceramics France, Universite de Lorraine, Center National de la Recherche Scientific (C.N.R.S.)
Abstract: The invention concerns a multilayer material comprising at least: a support having a reflectance R higher than 80% for radiations of wavelengths higher than 5 ?m, a selective layer comprising a combination of Vanadium oxides VO2 and VO2O2n+/?1, with n>1, said selective layer having an absorbance higher than 75% for radiations of wavelengths comprised between 0.4 and 2.5 ?m, regardless of the temperature T, and having, for radiations of wavelengths comprised between 6 and 10 ?m, a transmittance Tr such that: Tr>85% for T<Tc, a critical temperature, 20%?Tr?50% for T>Tc. Application to the production of thermal solar panels having a low stagnation temperature and high performance.
Type:
Grant
Filed:
March 13, 2014
Date of Patent:
June 6, 2017
Assignees:
VIESSMANN FAULQUEMONT, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE, UNIVERSITE DE LORRAINE
Inventors:
David Mercs, Fabien Capon, Alan Corvisier
Abstract: The present invention relates to a peptide comprising at least 6 consecutive amino acid selected from the amino acid sequence SEQ ID NO: 2 and a function-conservative variant. The invention also relates to a peptide comprising at least 6 consecutive amino acid selected from the amino acid sequence SEQ ID NO: 1 or SEQ ID NO: 2 and a function-conservative variant for use in the treatment of a cardiovascular disease.
Type:
Grant
Filed:
September 9, 2013
Date of Patent:
May 23, 2017
Assignees:
INSERM (INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE), UNIVERSITE DE LORRAINE
Inventors:
Sebastien Gibot, Amir Boufenzer, Hafid Ait-Oufella, Marc Derive
Abstract: A process for separating a gaseous or liquid mixture by means of a separating device including a first volume and a second volume which are separated by a membrane which has selective permeability with respect to at least two components of the mixture, comprising the following steps: a) fill up the first volume of the device with the mixture to be separated; b) wait for a period of time which is in excess of the permeation lag time, but is insufficient to reach a state of equilibrium, during which time a fraction of each component of the mixture passes from the first to the second volume of the device through the membrane; and c) evacuate the first and the second volume of the device, as a result of which at least one first and one second cut of the mixture is obtained, having different molar compositions.
Type:
Grant
Filed:
November 20, 2012
Date of Patent:
April 18, 2017
Assignees:
Centre National de la Recherche Scientifique, Universite de Lorraine
Inventors:
Eric Favre, Jean-Pierre Corriou, Christophe Castel, Lei Wang
Abstract: The present invention relates to methods and pharmaceutical compositions for the treatment of cardiovascular fibrosis. In particular, the present invention relates to an inhibitor of Neutrophil Gelatinase-Associated Lipocalin (NGAL) activity or expression for use in a method for treating or preventing cardiovascular fibrosis in a subject in need thereof.
Type:
Grant
Filed:
September 27, 2013
Date of Patent:
March 14, 2017
Assignees:
INSERM (Institut National de la Sante et de la Recherche Medicale), Universite de Lorraine, Cantre Hospitalier et Universitaire de Nancy (CHU), Universite Paris Diderot-Paris 7, Universite Paris Descartes
Inventors:
Frederic Jaisser, Nicolette Farman, Antoine Tarjus, Patrick Rossignol, Faiez Zannad
Abstract: A reversible matrix converter circuit is provided with n levels per phase including n conversion arms exhibiting on one side n ends for generating or receiving respectively n intermediate DC voltage levels, and exhibiting on another side n ends linked at a common point of AC signal input or output. The circuit includes: —two external arms linked respectively to the highest level of positive voltage and to the lowest level of negative voltage, these two external arms each having a single IGBT transistor or two power transistors, linked by their emitter, —two IGBT power transistors, linked in series by their emitter on each of the n?1 internal arms, —filtering capacitors disposed respectively between the n intermediate voltage levels.
Abstract: The present invention relates to thiazolidinedione derivatives, to the processes for preparing same and to the therapeutic use thereof for preventing or treating cancer, and more specifically breast cancer. These compounds are of formula (I) and exhibit, at a concentration of 100 ?M, a hepatocyte viability preferably greater than 60%, preferably greater than 80% and more preferentially greater than 85%.
Type:
Grant
Filed:
January 25, 2013
Date of Patent:
December 20, 2016
Assignees:
UNIVERSITE DE LORRAINE, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE—CNRS
Inventors:
Michel Boisbrun, Yves Chapleur, Andrea Bordessa, Stephane Flament, Isabelle Grillier-Vuissoz, Sandra Kuntz
Abstract: According to a thermomechanical treatment process for a titanium alloy including between 23 and 27% niobium in atomic proportion, between 0 and 10% zirconium, and between 0 and 1% oxygen, nitrogen and/or silicon, the following steps are performed: a) an increase of a sample of the alloy to a temperature higher than 900° C., b) a fast quench, c) a severe cold strain, d) an ageing treatment at a temperature included between 200 and 600° C., the time of the ageing treatment being included between 10 seconds and 10 minutes. Alloy obtained by this process and prostheses made from such an alloy.
Type:
Grant
Filed:
November 7, 2012
Date of Patent:
October 11, 2016
Assignees:
UNIVERSITE DE LORRAINE, ECOLE NATIONALE D INGENIEURS DE METZ (ENIM), ARTS, INSTITUT NATIONAL DES SCIENCES APPLIQUEES DE RENNES (INSA DE RENNES), NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CRNS)
Abstract: Process for depositing a corrosion-protection coating on at least one portion of the surfaces of a metallic substrate having at least one cavity with an equivalent diameter emm<2 mm and a length/width ratio of greater than 150, using an aqueous suspension comprising powder of the metal to be deposited on the substrate combined with an agent for protecting the surface of the metal powder, a diluent, and at least one additive, the particles of the suspension each having an equivalent diameter d such that d?emm/10.
Type:
Application
Filed:
September 17, 2014
Publication date:
August 18, 2016
Applicants:
L'Air Liquide, Societe Anonyme pour l'Etude et l'Exploitation des Procedes Georges Claude, Centre National de la Recherche Scientifique, Universite de Limoges, Universite de Lorraine
Inventors:
Thierry CHARTIER, Pascal DEL-GALLO, Sebastien DOUBLET, Thierry MAZET, Laurent PROST, Nicolas RAMENATTE, Fabrice ROSSIGNOL, Michel VILASI
Abstract: A composition for manufacturing a foam material based on flavonoid tannins, includes a flavonoid tannin powder mainly of the prorobineditinidin and/or the profisetinidin type, according to an amount in weight in the range between 40% and 45% of the composition, furfuryl alcohol, a blowing agent, and a catalyst. The composition is totally formaldehyde-free, and contains an amount of furfuryl alcohol greater than 20% in weight of the composition. The composition makes possible to obtain foam materials of high characteristics and low cost, that can typically be used in the fields of building and in the automotive industry and in the vehicles in general.
Type:
Grant
Filed:
July 18, 2012
Date of Patent:
April 5, 2016
Assignees:
SILVACHIMICA S.R.L., UNIVERSITE DE LORRAINE
Inventors:
Antonio Pizzi, Maria Cecilia Basso, Alain Celzard, Vanessa Fierro, Samuele Giovando
Abstract: Process for producing an element comprising a multilayer architecture, the layers of which comprise primary channels on their upper faces, said process comprising the following successive steps: (a) producing secondary channels on the lower faces of each layer, each secondary channel being intended to be facing a primary channel of the neighboring lower layer within the architecture, (b) depositing a coating that protects against oxidation at a temperature of between 500° C. and 1000° C. and against corrosion over all of the lower and upper surfaces of the layers, (c) sanding or mechanical cleaning of the surfaces intended to be assembled, and (d) assembling via superposition of the various layers so that each secondary channel of a lower face of an upper layer is facing and is centered on a primary channel of the neighboring lower layer, the width of each secondary channel being greater than the width of the primary channel which it is facing within the architecture.
Type:
Application
Filed:
March 17, 2014
Publication date:
March 3, 2016
Applicants:
L'AIR LIQUIDE, SOCIETE ANONYME POUR L'ETUDE ET L'EXPLOITATION DES PROCEDES GEORGES CLAUDE, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE, UNIVERSITE DE LORRAINE
Abstract: A polypeptide comprising one or more sequences derived from CDR2 or CDR3 of a TREM-1 protein, characterized by the ability to treat, ameliorate, or lessen the symptoms of conditions including sepsis, septic shock or sepsis-like conditions and IBD.
Type:
Grant
Filed:
July 12, 2011
Date of Patent:
March 1, 2016
Assignees:
Universite de Lorraine, Bristol-Myers Squibb
Abstract: A method is provided of reconstructing imaging signals in a biological medium on the basis of experimental measurements perturbed by movements, implementing measurements representative of the movements, at least one model of movement including movement parameters, and an imaging sampling grid, which method furthermore includes steps of (i) constructing a movement sampling grid by selecting a restricted set of points on the basis of the imaging sampling grid, and (ii) calculation of movement parameters by inverting a linear system at the points of the movement sampling grid. Devices implementing the method are also disclosed.
Type:
Grant
Filed:
December 11, 2012
Date of Patent:
March 1, 2016
Assignees:
UNIVERSITE DE LORRAINE, CENTRE HOSPITALIER REGIONAL DE NANCY
Inventors:
Anne Menini, Jacques Felblinger, Freddy Odille, Pierre-Andre Vuissoz
Abstract: Polypeptide The present invention relates to polypeptides fragments derived from the protein TLT-1 have been isolated and are useful in pharmaceutical preparations used for the treatment of inflammatory conditions such as sepsis.
Type:
Grant
Filed:
April 8, 2011
Date of Patent:
February 9, 2016
Assignees:
Institut National de la Sante et de la Recherche Medicale (INSERM), Universite de Lorraine
Abstract: The invention concerns a multilayer material comprising at least: a support having a reflectance R higher than 80% for radiations of wavelengths higher than 5 ?m, a selective layer comprising a combination of Vanadium oxides VO2 and VO2O2n+/?1, with n>1, said selective layer having an absorbance higher than 75% for radiations of wavelengths comprised between 0.4 and 2.5 ?m, regardless of the temperature T, and having, for radiations of wavelengths comprised between 6 and 10 ?m, a transmittance Tr such that: Tr>85% for T<Tc, a critical temperature, 20%?Tr?50% for T>Tc. Application to the production of thermal solar panels having a low stagnation temperature and high performance.
Type:
Application
Filed:
March 13, 2014
Publication date:
February 4, 2016
Applicants:
VIESSMANN FAULQUEMONT, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE, UNIVERSITE DE LORRAINE
Inventors:
David Mercs, Fabien Capon, Alan Corvisier
Abstract: The present invention relates to glycoside-derived compounds, to the processes for preparing same and to the use thereof as prosthetic groups for radiolabelling biomolecules. These compounds are co-azido-alkyl 6-deoxy-6-[18F]-fluoroglycosides of formula (I), in which: k is equal to 2 or 3; n is an integer between 1 and 5; R is independently H or a C1-C5 alkyl group, m being an integer between 0 and 2 if k=2 and m between 0 and 3 if k=3; and X is chosen from the group comprising O, S, CH2 and NR?, in which R? is independently a C1-C5 alkyl group or an aryl group, including all the stereoisomers thereof.
Type:
Application
Filed:
July 2, 2013
Publication date:
February 4, 2016
Applicants:
UNIVERSITE DE LORRAINE, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE - CNRS
Inventors:
YVES CHAPLEUR, Sandrine LAMANDE, Charlotte COLLET, Françoise CHRETIEN