Patents Assigned to Universite de Liege
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Publication number: 20100137240Abstract: The present invention relates to the use of N-phosphonylmethoxyethyl nucleoside analogs for manufacturing a medicament for the treatment or prevention of Koi Herpes virus infections in fish, especially in carps.Type: ApplicationFiled: May 16, 2008Publication date: June 3, 2010Applicants: Katholieke Universiteit Leuven, Universite de LiegeInventors: Berenice Costes, Johan Neyts, Alain Vanderplasschen
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Patent number: 7728112Abstract: A method for improving the diagnostic assessment of cartilage degenerative processes, and to provide means of monitoring the effects of therapeutical measures taken towards arthritic diseases in most mammals utilizes an immunoassay to detect fragments of collagen type II resulting from collagenase activity comprising an antibody directed against an epitope comprised in the amino acid sequence HRGYPGLDG (SEQ ID NO:1), located in the helical region of collagen type II.Type: GrantFiled: August 7, 2008Date of Patent: June 1, 2010Assignee: Universite de LiegeInventors: Jean-Yves Reginster, Michelle Deberg, Yves Henrotin, Stephan Christgau
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Patent number: 7655626Abstract: The present invention refers to a pharmaceutical composition comprising an isolated antiangiogenic peptide or a recombinant protein comprising the antiangiogenic peptide, wherein the peptide is between 11 and 40 amino acids in length and having antiangiogenic activity, the peptide comprising the amino acid sequence: X1-X2-X3-X4-X5-X6-X7-X8-X9-X10-X11-X12-X13-X14, wherein X1 is any amino acid residue compatible with forming a helix; X2 is an amino acid residue of: Leu, Ile, Val; X3 is an amino acid residue of: Arg, Lys, His, Ser, Thr; X4 is an amino acid residue of: Ile, Leu, Val; X5 is any amino acid residue compatible with forming a helix; X6 is an amino acid residue of: Leu, Ile, Val; X7 is an amino acid residue of: Leu, Ile, Val, Ser, Thr; X8 is any amino acid residue compatible with forming a helix; X9 is any amino acid residue compatible with forming a helix; X10 is an amino acid residue of: Gln, Glu, Asp, Arg, His, Lys, Asn; X11 is an amino acid residue of: Ser, Thr; X12 is an amino acid residue of: TrpType: GrantFiled: August 11, 2005Date of Patent: February 2, 2010Assignees: Universite de Liege, Faculte Universitaire des Sciences Agronomiques de GemblouxInventors: Joseph Martial, Ingrid Struman, Ngoc-Quynh-Nhu Nguyen, Robert Brasseur, Laurence Lins
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Publication number: 20090306459Abstract: A new, quick, simple, efficient, safe, and reproducible surgical technique for the treatment of female urinary incontinence, in which the posterior urethra is suspended using a tape passed through the obturator orifices from inside (underneath the urethra) to outside (thigh folds). A variety of specifically designed surgical instruments are utilized to perform this operative procedure.Type: ApplicationFiled: August 12, 2009Publication date: December 10, 2009Applicant: Universite de Liege and centre Hospitalier Universitaire de LiegeInventor: Jean De Leval
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Patent number: 7611454Abstract: A new, quick, simple, efficient, safe, and reproducible surgical technique for the treatment of female urinary incontinence, in which the posterior urethra is suspended using a tape passed through the obturator orifices from inside (underneath the urethra) to outside (thigh folds). A variety of specifically designed surgical instruments are utilized to perform this operative procedure.Type: GrantFiled: May 27, 2004Date of Patent: November 3, 2009Assignees: Universite De Liege, Centre Hospitalier Universitaire De LiegeInventor: Jean De Leval
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Patent number: 7507761Abstract: The invention relates to novel benzopyran derivatives of formula I, to their method of production, to composition comprising the derivatives and use thereof.Type: GrantFiled: January 21, 2005Date of Patent: March 24, 2009Assignees: Universite de Liege, Universite Libre de BruxellesInventors: Sophie Sebille, Bernard Pirotte, Stéphane Boverie, Pascal De Tullio, Philippe Lebrun, Marie-Hélène Antoine
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Publication number: 20090042220Abstract: A method for improving the diagnostic assessment of cartilage degenerative processes, and to provide means of monitoring the effects of therapeutical measures taken towards arthritic diseases in most mammals utilizes an immunoassay to detect fragments of collagen type II resulting from collagenase activity comprising an antibody directed against an epitope comprised in the amino acid sequence HRGYPGLDG (SEQ ID NO:1), located in the helical region of collagen type II.Type: ApplicationFiled: August 7, 2008Publication date: February 12, 2009Applicant: Universite de LiegeInventors: Jean-Yves Reginster, Michelle Deberg, Yves Henrotin, Stephan Christgau
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Patent number: 7410770Abstract: A method for improving the diagnostic assessment of cartilage degenerative processes, and to provide means of monitoring the effects of therapeutical measures taken towards arthritic diseases in most mammals utilizes an immunoassay to detect fragments of collagen type II resulting from collagenase activity comprising an antibody directed against an epitope comprised in the amino acid sequence HRGYPGLDG, located in the helical region of collagen type II.Type: GrantFiled: March 12, 2003Date of Patent: August 12, 2008Assignee: Universite De LiegeInventors: Jean-Yves Reginster, Michelle Deberg, Yves Henrotin, Stephan Christgau
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Patent number: 7393649Abstract: Methods are described for improving the diagnostic possibilities of diseases where oxidative NO-modifications occur, for example inflammatory conditions, cancer, Parkinson's or Alzheimer's disease, and to provide means of monitoring the effects of therapeutical measures taken towards such diseases. The invention enables the detection of disease specific catabolic markers related to oxidative NO-modifications, utilizing an immunoassay comprising antibodies directed against nitrated and non-nitrated epitopes characteristic of a specific protein.Type: GrantFiled: March 12, 2003Date of Patent: July 1, 2008Assignee: Universite de LiegeInventors: Jean-Yves Reginster, Michelle Deberg, Yves Henrotin, Stephan Christgau
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Publication number: 20080086272Abstract: A method and a computer-based system for determining a classifier for a biological condition of a specific disease, an essay and a kit for assessing whether a subject is afflicted with such specific disease.Type: ApplicationFiled: August 29, 2005Publication date: April 10, 2008Applicant: Universite de Liege Quai Van Beneden, 25Inventor: Marianne Fillet
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Patent number: 7319189Abstract: A space solar concentrator based on deployable reflectors attached to a panel base is described. Each of the reflectors includes sides coated with reflective coating on surfaces facing away from the base. In one embodiment, the sides of the reflector have thicker portion to provide stiffness for deployment absent compressive force, and thinner portion to reduce weight and storage energy. In another embodiment, both reflective sides are unfolded when the reflectors are in stowed position. During deployment, a stop side will limit the deployment of both reflective sides and ensure the proper reflecting position. In addition, these embodiments reduce the storage energy.Type: GrantFiled: October 27, 2004Date of Patent: January 15, 2008Assignee: Universite de LiegeInventors: Vincent Ruelle, Serge Habraken, Jean-Paul Collette
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Patent number: 7204802Abstract: A new, quick, simple, efficient, safe, and reproducible surgical technique for the treatment of female urinary incontinence, in which the posterior urethra is suspended using a tape passed through the obturator orifices from inside (underneath the urethra) to outside (thigh folds). A variety of specifically designed surgical instruments are utilized to perform this operative procedure.Type: GrantFiled: July 29, 2003Date of Patent: April 17, 2007Assignees: Universite de Liege, Centre Hospitalier Universitaire de LiegeInventor: Jean De Leval
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Patent number: 7132825Abstract: A device for detecting the displacement of an object comprising a ferromagnetic material, comprises a magnetic circuit generator provided with first and a second cores made of ferromagnetic material and an excitation coil and a measurement coil. The magnetic circuit generator is connected to a detecting unit designed to detect a reluctance variation brought about in the circuit by the displacement of the object and to deduce therefrom its position. In the device, the magnetic circuit generator comprises first and second transformers with open magnetic circuit, the transformers being juxtaposed and comprise each an axis extending across their respective core, the axes extending substantially perpendicular to the path. The excitation coil comprises two coils connected in series which form the primary windings of the first and second transformers.Type: GrantFiled: August 6, 2002Date of Patent: November 7, 2006Assignee: Universite de LiegeInventor: Nicolas Martin
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Patent number: 6903261Abstract: A solar concentrator module comprising a front lens on its front face, a receiver cell on its rear face and a reflector between the front lens and the receiver cell, said reflector having inclined sidewalls along at least two opposite sides of the receiver cell characterised in that the reflectors are truncated and in that the sidewalls of the reflectors are inclined in such a way that, for a 0[deg] off-pointing, solar rays are reflected on the inclined side walls of the reflectors before impinging on the receiver cell, to produce a relatively uniform illumination on the receiver cell for a range of off pointing acceptance angle superior to zero degree.Type: GrantFiled: May 17, 2002Date of Patent: June 7, 2005Assignee: Universite de LiegeInventors: Serge Habraken, Jean-Marc Defise, Jean-Paul Collette
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Patent number: 6860163Abstract: The present invention is related to a device for the measurement of the photosynthesis of a whole small plant, which comprises: a rigid base of very low thickness that fits between the plant and its substrate in order to isolate it from the inside of a chamber, a central unit containing all the electronic and mechanical equipment required for the functioning of the chamber, a chamber that is a container whose size and volume are adapted at the same time to the central unit, to its base, and to the size of the plant to be studied.Type: GrantFiled: June 18, 2003Date of Patent: March 1, 2005Assignee: Universite de LiegeInventors: Pierre Tocquin, Claire Perilleux
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Patent number: 6852799Abstract: Product, method and use of a copolymer AB as a compatibilizing agent between a polar thermoplastic polymer C and a polyolefine D. The method of making AB comprise the steps of: a) melting a copolymer (A) comprising a larger amount of methylmethacrylate units and a smaller amount of functional vinyl or (meth)acrylate units wherein functional moiety is selected in the group consisting of (a hydroxyl, a carboxylic, a glycidyl or an amine functional group); together with maleic anhydride grafted polypropylene (B) allowing condensation reaction to occur between the functions under “A” and the anhydride under “B”; b) the condensation copolymer obtained under a) is further melt together with the two polymers C and D to be homogenized, or melt processed as an interlayer between the two molten polymers.Type: GrantFiled: September 10, 2001Date of Patent: February 8, 2005Assignee: Universite de LiegeInventors: Alexandre Baidak, Christine Brassine, Jean-Marie Liegeois, Trazollah Ouhadi
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Patent number: 6818765Abstract: Benzene-sulphonamide derivatives complying with the general formula (I): in which the different symbols have different meanings, their optical isomers and the salts pharmacologically acceptable of these derivatives, as well as their uses for drug manufacture and as radiolabelled pharmacological tools of the thromboxan A2 receptors.Type: GrantFiled: October 16, 2001Date of Patent: November 16, 2004Assignee: Universite de LiegeInventors: Jacques Delarge, Jean-Michel Dogne, Bernard Masereel
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Patent number: 6727084Abstract: A purified cold-active beta galactosidase enzyme, specific for lactose, having a stable enzymatic activity at a temperature below 8° C. In the presence of lactose, a purified cold-active beta galactosidase enzyme, specific for lactose, having a stable enzymatic activity at a temperature ranging between 0° C. and 50° C.Type: GrantFiled: February 9, 2000Date of Patent: April 27, 2004Assignee: Universite de LiegeInventors: Anne Hoyoux, Jean-Marie François, Phillip Dubois, Etienne Baise, Isabell Jennes, Sabine Genicot, Charles Gerday
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Patent number: 6667037Abstract: The invention relates to peptides which bind to HLA-B35 molecules, leading to recognition and lysis of the resulting complexes by cytolytic T cells. Also a part of the invention are nucleic acid molecules which encode these peptides, and uses of each of these. The molecules are derived, in some cases, from tyrosinase, and portions of the tyrosinase molecule and portions of nucleic acid molecules which encode tyrosinase are also a part of the invention.Type: GrantFiled: October 9, 1998Date of Patent: December 23, 2003Assignees: Ludwig Institute for Cancer Research, Universite de LiegeInventors: Annie Ooms, Gérard De Giiovanni, Sandra Morel, Benoît Van Den Eynde, Thierry Boon-Falleur
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Patent number: 6575584Abstract: An illumination device comprising a plate provided for guiding light there through, having an input for receiving an input light beam to be injected into said plate and an array of N micro-prisms for receiving the input light beam and producing an output light beam from the input light beam. The array of micro-prisms is located inside the plate.Type: GrantFiled: April 14, 2000Date of Patent: June 10, 2003Assignee: Universite De LiegeInventor: Serge Habraken