Patents Assigned to Universite de Liege
  • Publication number: 20100137240
    Abstract: The present invention relates to the use of N-phosphonylmethoxyethyl nucleoside analogs for manufacturing a medicament for the treatment or prevention of Koi Herpes virus infections in fish, especially in carps.
    Type: Application
    Filed: May 16, 2008
    Publication date: June 3, 2010
    Applicants: Katholieke Universiteit Leuven, Universite de Liege
    Inventors: Berenice Costes, Johan Neyts, Alain Vanderplasschen
  • Patent number: 7728112
    Abstract: A method for improving the diagnostic assessment of cartilage degenerative processes, and to provide means of monitoring the effects of therapeutical measures taken towards arthritic diseases in most mammals utilizes an immunoassay to detect fragments of collagen type II resulting from collagenase activity comprising an antibody directed against an epitope comprised in the amino acid sequence HRGYPGLDG (SEQ ID NO:1), located in the helical region of collagen type II.
    Type: Grant
    Filed: August 7, 2008
    Date of Patent: June 1, 2010
    Assignee: Universite de Liege
    Inventors: Jean-Yves Reginster, Michelle Deberg, Yves Henrotin, Stephan Christgau
  • Patent number: 7655626
    Abstract: The present invention refers to a pharmaceutical composition comprising an isolated antiangiogenic peptide or a recombinant protein comprising the antiangiogenic peptide, wherein the peptide is between 11 and 40 amino acids in length and having antiangiogenic activity, the peptide comprising the amino acid sequence: X1-X2-X3-X4-X5-X6-X7-X8-X9-X10-X11-X12-X13-X14, wherein X1 is any amino acid residue compatible with forming a helix; X2 is an amino acid residue of: Leu, Ile, Val; X3 is an amino acid residue of: Arg, Lys, His, Ser, Thr; X4 is an amino acid residue of: Ile, Leu, Val; X5 is any amino acid residue compatible with forming a helix; X6 is an amino acid residue of: Leu, Ile, Val; X7 is an amino acid residue of: Leu, Ile, Val, Ser, Thr; X8 is any amino acid residue compatible with forming a helix; X9 is any amino acid residue compatible with forming a helix; X10 is an amino acid residue of: Gln, Glu, Asp, Arg, His, Lys, Asn; X11 is an amino acid residue of: Ser, Thr; X12 is an amino acid residue of: Trp
    Type: Grant
    Filed: August 11, 2005
    Date of Patent: February 2, 2010
    Assignees: Universite de Liege, Faculte Universitaire des Sciences Agronomiques de Gembloux
    Inventors: Joseph Martial, Ingrid Struman, Ngoc-Quynh-Nhu Nguyen, Robert Brasseur, Laurence Lins
  • Publication number: 20090306459
    Abstract: A new, quick, simple, efficient, safe, and reproducible surgical technique for the treatment of female urinary incontinence, in which the posterior urethra is suspended using a tape passed through the obturator orifices from inside (underneath the urethra) to outside (thigh folds). A variety of specifically designed surgical instruments are utilized to perform this operative procedure.
    Type: Application
    Filed: August 12, 2009
    Publication date: December 10, 2009
    Applicant: Universite de Liege and centre Hospitalier Universitaire de Liege
    Inventor: Jean De Leval
  • Patent number: 7611454
    Abstract: A new, quick, simple, efficient, safe, and reproducible surgical technique for the treatment of female urinary incontinence, in which the posterior urethra is suspended using a tape passed through the obturator orifices from inside (underneath the urethra) to outside (thigh folds). A variety of specifically designed surgical instruments are utilized to perform this operative procedure.
    Type: Grant
    Filed: May 27, 2004
    Date of Patent: November 3, 2009
    Assignees: Universite De Liege, Centre Hospitalier Universitaire De Liege
    Inventor: Jean De Leval
  • Patent number: 7507761
    Abstract: The invention relates to novel benzopyran derivatives of formula I, to their method of production, to composition comprising the derivatives and use thereof.
    Type: Grant
    Filed: January 21, 2005
    Date of Patent: March 24, 2009
    Assignees: Universite de Liege, Universite Libre de Bruxelles
    Inventors: Sophie Sebille, Bernard Pirotte, Stéphane Boverie, Pascal De Tullio, Philippe Lebrun, Marie-Hélène Antoine
  • Publication number: 20090042220
    Abstract: A method for improving the diagnostic assessment of cartilage degenerative processes, and to provide means of monitoring the effects of therapeutical measures taken towards arthritic diseases in most mammals utilizes an immunoassay to detect fragments of collagen type II resulting from collagenase activity comprising an antibody directed against an epitope comprised in the amino acid sequence HRGYPGLDG (SEQ ID NO:1), located in the helical region of collagen type II.
    Type: Application
    Filed: August 7, 2008
    Publication date: February 12, 2009
    Applicant: Universite de Liege
    Inventors: Jean-Yves Reginster, Michelle Deberg, Yves Henrotin, Stephan Christgau
  • Patent number: 7410770
    Abstract: A method for improving the diagnostic assessment of cartilage degenerative processes, and to provide means of monitoring the effects of therapeutical measures taken towards arthritic diseases in most mammals utilizes an immunoassay to detect fragments of collagen type II resulting from collagenase activity comprising an antibody directed against an epitope comprised in the amino acid sequence HRGYPGLDG, located in the helical region of collagen type II.
    Type: Grant
    Filed: March 12, 2003
    Date of Patent: August 12, 2008
    Assignee: Universite De Liege
    Inventors: Jean-Yves Reginster, Michelle Deberg, Yves Henrotin, Stephan Christgau
  • Patent number: 7393649
    Abstract: Methods are described for improving the diagnostic possibilities of diseases where oxidative NO-modifications occur, for example inflammatory conditions, cancer, Parkinson's or Alzheimer's disease, and to provide means of monitoring the effects of therapeutical measures taken towards such diseases. The invention enables the detection of disease specific catabolic markers related to oxidative NO-modifications, utilizing an immunoassay comprising antibodies directed against nitrated and non-nitrated epitopes characteristic of a specific protein.
    Type: Grant
    Filed: March 12, 2003
    Date of Patent: July 1, 2008
    Assignee: Universite de Liege
    Inventors: Jean-Yves Reginster, Michelle Deberg, Yves Henrotin, Stephan Christgau
  • Publication number: 20080086272
    Abstract: A method and a computer-based system for determining a classifier for a biological condition of a specific disease, an essay and a kit for assessing whether a subject is afflicted with such specific disease.
    Type: Application
    Filed: August 29, 2005
    Publication date: April 10, 2008
    Applicant: Universite de Liege Quai Van Beneden, 25
    Inventor: Marianne Fillet
  • Patent number: 7319189
    Abstract: A space solar concentrator based on deployable reflectors attached to a panel base is described. Each of the reflectors includes sides coated with reflective coating on surfaces facing away from the base. In one embodiment, the sides of the reflector have thicker portion to provide stiffness for deployment absent compressive force, and thinner portion to reduce weight and storage energy. In another embodiment, both reflective sides are unfolded when the reflectors are in stowed position. During deployment, a stop side will limit the deployment of both reflective sides and ensure the proper reflecting position. In addition, these embodiments reduce the storage energy.
    Type: Grant
    Filed: October 27, 2004
    Date of Patent: January 15, 2008
    Assignee: Universite de Liege
    Inventors: Vincent Ruelle, Serge Habraken, Jean-Paul Collette
  • Patent number: 7204802
    Abstract: A new, quick, simple, efficient, safe, and reproducible surgical technique for the treatment of female urinary incontinence, in which the posterior urethra is suspended using a tape passed through the obturator orifices from inside (underneath the urethra) to outside (thigh folds). A variety of specifically designed surgical instruments are utilized to perform this operative procedure.
    Type: Grant
    Filed: July 29, 2003
    Date of Patent: April 17, 2007
    Assignees: Universite de Liege, Centre Hospitalier Universitaire de Liege
    Inventor: Jean De Leval
  • Patent number: 7132825
    Abstract: A device for detecting the displacement of an object comprising a ferromagnetic material, comprises a magnetic circuit generator provided with first and a second cores made of ferromagnetic material and an excitation coil and a measurement coil. The magnetic circuit generator is connected to a detecting unit designed to detect a reluctance variation brought about in the circuit by the displacement of the object and to deduce therefrom its position. In the device, the magnetic circuit generator comprises first and second transformers with open magnetic circuit, the transformers being juxtaposed and comprise each an axis extending across their respective core, the axes extending substantially perpendicular to the path. The excitation coil comprises two coils connected in series which form the primary windings of the first and second transformers.
    Type: Grant
    Filed: August 6, 2002
    Date of Patent: November 7, 2006
    Assignee: Universite de Liege
    Inventor: Nicolas Martin
  • Patent number: 6903261
    Abstract: A solar concentrator module comprising a front lens on its front face, a receiver cell on its rear face and a reflector between the front lens and the receiver cell, said reflector having inclined sidewalls along at least two opposite sides of the receiver cell characterised in that the reflectors are truncated and in that the sidewalls of the reflectors are inclined in such a way that, for a 0[deg] off-pointing, solar rays are reflected on the inclined side walls of the reflectors before impinging on the receiver cell, to produce a relatively uniform illumination on the receiver cell for a range of off pointing acceptance angle superior to zero degree.
    Type: Grant
    Filed: May 17, 2002
    Date of Patent: June 7, 2005
    Assignee: Universite de Liege
    Inventors: Serge Habraken, Jean-Marc Defise, Jean-Paul Collette
  • Patent number: 6860163
    Abstract: The present invention is related to a device for the measurement of the photosynthesis of a whole small plant, which comprises: a rigid base of very low thickness that fits between the plant and its substrate in order to isolate it from the inside of a chamber, a central unit containing all the electronic and mechanical equipment required for the functioning of the chamber, a chamber that is a container whose size and volume are adapted at the same time to the central unit, to its base, and to the size of the plant to be studied.
    Type: Grant
    Filed: June 18, 2003
    Date of Patent: March 1, 2005
    Assignee: Universite de Liege
    Inventors: Pierre Tocquin, Claire Perilleux
  • Patent number: 6852799
    Abstract: Product, method and use of a copolymer AB as a compatibilizing agent between a polar thermoplastic polymer C and a polyolefine D. The method of making AB comprise the steps of: a) melting a copolymer (A) comprising a larger amount of methylmethacrylate units and a smaller amount of functional vinyl or (meth)acrylate units wherein functional moiety is selected in the group consisting of (a hydroxyl, a carboxylic, a glycidyl or an amine functional group); together with maleic anhydride grafted polypropylene (B) allowing condensation reaction to occur between the functions under “A” and the anhydride under “B”; b) the condensation copolymer obtained under a) is further melt together with the two polymers C and D to be homogenized, or melt processed as an interlayer between the two molten polymers.
    Type: Grant
    Filed: September 10, 2001
    Date of Patent: February 8, 2005
    Assignee: Universite de Liege
    Inventors: Alexandre Baidak, Christine Brassine, Jean-Marie Liegeois, Trazollah Ouhadi
  • Patent number: 6818765
    Abstract: Benzene-sulphonamide derivatives complying with the general formula (I): in which the different symbols have different meanings, their optical isomers and the salts pharmacologically acceptable of these derivatives, as well as their uses for drug manufacture and as radiolabelled pharmacological tools of the thromboxan A2 receptors.
    Type: Grant
    Filed: October 16, 2001
    Date of Patent: November 16, 2004
    Assignee: Universite de Liege
    Inventors: Jacques Delarge, Jean-Michel Dogne, Bernard Masereel
  • Patent number: 6727084
    Abstract: A purified cold-active beta galactosidase enzyme, specific for lactose, having a stable enzymatic activity at a temperature below 8° C. In the presence of lactose, a purified cold-active beta galactosidase enzyme, specific for lactose, having a stable enzymatic activity at a temperature ranging between 0° C. and 50° C.
    Type: Grant
    Filed: February 9, 2000
    Date of Patent: April 27, 2004
    Assignee: Universite de Liege
    Inventors: Anne Hoyoux, Jean-Marie François, Phillip Dubois, Etienne Baise, Isabell Jennes, Sabine Genicot, Charles Gerday
  • Patent number: 6667037
    Abstract: The invention relates to peptides which bind to HLA-B35 molecules, leading to recognition and lysis of the resulting complexes by cytolytic T cells. Also a part of the invention are nucleic acid molecules which encode these peptides, and uses of each of these. The molecules are derived, in some cases, from tyrosinase, and portions of the tyrosinase molecule and portions of nucleic acid molecules which encode tyrosinase are also a part of the invention.
    Type: Grant
    Filed: October 9, 1998
    Date of Patent: December 23, 2003
    Assignees: Ludwig Institute for Cancer Research, Universite de Liege
    Inventors: Annie Ooms, Gérard De Giiovanni, Sandra Morel, Benoît Van Den Eynde, Thierry Boon-Falleur
  • Patent number: 6575584
    Abstract: An illumination device comprising a plate provided for guiding light there through, having an input for receiving an input light beam to be injected into said plate and an array of N micro-prisms for receiving the input light beam and producing an output light beam from the input light beam. The array of micro-prisms is located inside the plate.
    Type: Grant
    Filed: April 14, 2000
    Date of Patent: June 10, 2003
    Assignee: Universite De Liege
    Inventor: Serge Habraken