Patents Assigned to UNIVERSITE DE LILLE
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Patent number: 12060301Abstract: The invention relates to a composite material based on boron nitride (BN(C)) in the form of a continuous structure; and a phase change material (PCM) incorporated within said continuous BN(C) structure and is embedded within a polymer layer, a process for manufacturing same, and the components that comprise same.Type: GrantFiled: December 21, 2018Date of Patent: August 13, 2024Assignees: THALES, UNIVERSITÉ DE LILLE, NANYANG TECHNOLOGICAL UNIVERSITY, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUEInventors: Matthieu Pawlik, Edwin Hang Tong Teo, Philippe Coquet
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Patent number: 12044620Abstract: A method for determining a set of physical parameters of a sample, comprising the steps of: —A Retrieving a measured sample temporal trace Es(t), —B retrieving a measured reference temporal trace Eref(t), —C determining an widened reference temporal trace, called Eref0(t), and determining a discrete Fourier transform {hacek over (E)}ref0(?) of the widened reference temporal trace—D determining a modeling of an impulse response of the sample in the frequency domain, depending on the set of physical parameters (pi), called sample frequency model {hacek over (E)}model{Pi}(?), from the Fourier Transform of the widened reference temporal trace {hacek over (E)}ref0(?) and a physical behavior model of the sample, —E applying an optimization algorithm on the set of physical parameters (pi) comprising the sub steps of: —E1 initializing physical parameters (pi), —realizing iteratively the sub steps of: —E2 calculating an inverse discrete Fourier transform of the sample frequency model {hacek over (E)}model{Pi}(?), callType: GrantFiled: February 11, 2021Date of Patent: July 23, 2024Assignees: CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE, CENTRALE LILLE INSTITUT, UNIVERSITE DE LILLE, UNIVERSITE POLYTECHNIQUE HAUTE-DE-FRANCE, JUNIAInventor: Romain Peretti
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Publication number: 20240181995Abstract: The invention relates to a device (5) comprising an optical surface (10) and a cleaning device (15) for cleaning the optical surface comprising:— a wave transducer (25) acoustically coupled with the optical surface and configured to synthesize an ultrasound wave (W) propagating within the optical surface, and— a spraying unit (20) for dispensing a washing liquid (L) onto the optical surface, the device being shaped so that the ultrasound wave displaces the washing liquid on the optical surface.Type: ApplicationFiled: March 29, 2022Publication date: June 6, 2024Applicants: UNIVERSITE DE LILLE, CENTRALE LILLE INSTITUT, UNIVERSITE POLYTECHNIQUE HAUTS-DE-FRANCE, Centre National de la Recherche Scientifique, Valeo Systèmes d'EssuyageInventors: Michaël Baudoin, Ravinder Chutani, Olivier Bou Matar-Lacaze, Frederic Bretagnol, Vincent Izabel, Gérald Caillot, Alexandre Filloux
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Publication number: 20240148778Abstract: A composition of yeast polysaccharides including ?(1,6)-glucans, preferably also mannans and ?-glucans. The yeast polysaccharides are extracted from yeast cell wall fragments. Typically, the ?-glucans are ?(1,6)-glucans. Also, a method for obtaining such a composition, including at least one step of fractionating a composition of yeast cell walls and extracting an insoluble fraction, and at least one step of extracting a soluble fraction from the insoluble fraction obtained in step a). Further, a composition with a human or veterinary therapeutic objective, for the treatment of gastrointestinal pathologies associated with pathogenic microorganisms, as well as to its non-therapeutic use for improving intestinal comfort.Type: ApplicationFiled: March 15, 2022Publication date: May 9, 2024Applicants: LESAFFRE ET COMPAGNIE, UNIVERSITÉ CLERMONT AUVERGNE, UNIVERSITE DE LILLE, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE - CNRSInventors: Nathalie BALLET, Pascal VANDEKERCKOVE, Yann GUERARDEL, Shin-Yi YU, Adeline SIVIGNON, Nicolas BARNICH
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Publication number: 20240142457Abstract: The use of CASD1 as a biomarker of a cancer expressing the O-acetylated-GD2 ganglioside. Also, a method of diagnosing a cancer expressing the O-acetylated-GD2 ganglioside, a method of selecting a subject suffering from a cancer expressing the O-acetylated-GD2 ganglioside for treatment targeting the cancer, or a method of monitoring the response of a subject suffering from a cancer expressing the O-acetylated-GD2 ganglioside to a treatment targeting the cancer.Type: ApplicationFiled: June 10, 2022Publication date: May 2, 2024Applicants: OGD2 PHARMA, UNIVERSITE DE LILLE, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUEInventors: Sophie GROUX-DEGROOTE, Philippe DELANNOY, Sumeyye CAVDARLI, Jean-Marc LE DOUSSAL, Angélina KASPROWICZ
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Publication number: 20240146065Abstract: A method for controlling an electric microgrid comprising an electrical energy consuming element, an electrical energy production element and an electrical energy storage element, the method comprising the steps of extracting parameter values from a source model, the extraction phase being implemented by computer, initializing parameters of a target model with parameter values extracted from the source model, so as to obtain an initialized target model, the initialization phase being implemented by computer, and optimizing, according to a target domain and a target set of tasks, of the parameters of the initialized target model, so as to obtain a target model trained for the control of a target microgrid, the optimization phase being implemented by computer.Type: ApplicationFiled: December 23, 2021Publication date: May 2, 2024Applicants: Centre national de la recherche scientifique, Université de Lille, ECOLE POLYTECHNIQUE, TotalEnergies OneTechInventors: Gonzague HENRI, Philippe CORDIER, Tanguy LEVENT, Philippe PREUX, Yves BONNASSIEUX
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Patent number: 11971310Abstract: An optical fibre, for use in the field of distributed measurement of temperature or deformation by optical reflectometry in the frequency domain using the Rayleigh backscattered signal in the fibre, includes a core doped with nanoparticles for example formed from gold particles covered with zirconium oxide, and can be subjected to high temperatures during the measurement. A method for producing the optical fibre includes a step of heat treatment during which the optical fibre is subjected, for a duration of at least one hour, to a heat treatment temperature higher than a maximum temperature to which it will be subjected during a measurement.Type: GrantFiled: June 21, 2019Date of Patent: April 30, 2024Assignees: COMMISSARIAT A L'ENERGIE ATOMIQUE ET ENERGIES ALTERNATIVES, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE, UNIVERSITE DE LILLEInventors: Patrick Bulot, Remy Bernard, Odile Cristini, Monika Bouet, Guillaume Laffont, Marc Douay
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Patent number: 11947101Abstract: According to one aspect, the invention relates to a device (200) for transporting and controlling light beams comprising a light guide (40) comprising a bundle (50) of uncoupled single-mode optical fibers (Fi), each single-mode optical fiber (Fi) being intended to receive an elementary light beam (B1i) at a proximal end and to emit a light beam (B2i) at a distal end, said bundle of single-mode optical fibers comprising, in operation, a minimum radius of curvature corresponding to a maximum curvature of the bundle of fibers.Type: GrantFiled: September 10, 2019Date of Patent: April 2, 2024Assignees: Centre National de la Recherche Scientifique, Université d'Aix-Marseille, Université de Lille, Ecole Centrale de MarseilleInventors: Hervé Rigneault, Géraud Bouwmans, Esben Andresen, Siddarth Sivankutty, Viktor Tsvirkun, Olivier Vanvincq
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Patent number: 11948548Abstract: A phonon parametric oscillator is provided. The phonon parametric oscillator comprises a laser for periodically emitting brief optical pulses (IL), an assembly for generating acoustic pulses (IA) and a medium for coupling the acoustic pulses to an object (O), the assembly for generating acoustic pulses comprising an entrance face, an exit face, a conversion medium for converting the brief optical pulses into acoustic pulses and a propagation medium for propagating said acoustic pulses, the entrance and exit faces being reflective to the acoustic pulses, the propagation medium having a defined thickness, the exit face making contact with the coupling medium. In the phonon parametric oscillator according to the invention, the round-trip time of an acoustic pulse due to reflection from the entrance and exit faces, is equal to the emission period (?) of the laser, so that the reflected acoustic pulse is in phase with the following acoustic pulse.Type: GrantFiled: February 8, 2019Date of Patent: April 2, 2024Assignees: CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE, JUNIA, UNIVERSITE DE LILLE, CENTRALE LILLE INSTITUTInventor: Arnaud Devos
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Patent number: 11926664Abstract: Monocytopoiesis is a hematological process that supplies the periphery with monocytes and subsequently with macrophages and monocyte-derived dendritic cells. Typically, monocytes circulate in the bloodstream for a very short time before undergoing apoptosis, however, stimulatory signals can trigger monocyte survival by inhibiting the apoptotic pathway, and thus contribute to the maintenance of the inflammatory response. Accordingly, there is a need for methods and pharmaceutical compositions for modulating monocytopoiesis. Now, the inventors show that type I interferons signaling promote the differentiation of monocyte-derived phagocytes at the level of their progenitors. Importantly, IFN-alpha and -beta were found to efficiently generate the development of monocyte-derived antigen-presenting cells while having no impact on the precursor activity of conventional dendritic cells. Accordingly, modulators of type I interferon (e.g.Type: GrantFiled: July 24, 2018Date of Patent: March 12, 2024Assignees: INSERM (INSTITUT NATIONAL DE LA SANTÉ ET DE LA RECHERCHE MÉDICALE), INSTITUT PASTEUR DE LILLE, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS), UNIVERSITÉ DE LILLEInventors: Lionel Poulin, Corentin Lasseaux, Mathias Chamaillard
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Patent number: 11919854Abstract: The present invention relates to compounds of formula (I), their enantiomers and their pharmaceutically acceptable salts, and their use in therapy, particularly for the treatment of cancer or inflammatory diseases.Type: GrantFiled: March 29, 2019Date of Patent: March 5, 2024Assignees: CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE, CHRU DE LILLE, UNIVERSITE COTE D'AZUR, INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM), UNIVERSITE DE LILLE, JUNIAInventors: Valérie Vouret, Laetitia Douguet, Alina Ghinet, Germain Homerin, Benoît Guy Marie Rigo, Davy Jérémy Baudelet, Xavier Dezitter, Régis Millet, Christophe Furman
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Publication number: 20240043626Abstract: A method for the selective cleavage of a compound comprising an aromatic ring and a C—O—C linkage in the presence of a heterogeneous catalyst is provided. The heterogenous catalyst may be a supported noble metal catalyst doped with a halogen selected from the group consisting of chlorine and bromine. By using this method, it is possible to increase the selectivity and/or yield (preferably both) of aromatic compounds.Type: ApplicationFiled: December 14, 2020Publication date: February 8, 2024Applicants: RHODIA OPERATIONS, LE CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE, UNIVERSITE DE LILLE, CENTRALE LILLE INSTITUTInventors: Dan Wu, Vitaly Ordomsky, Andrei Khodakov, Stephane Streiff, Jianxia Zheng
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Patent number: 11894830Abstract: A surface acoustic wave device includes at least one transducer; two acoustic reflectors disposed on either side of the at least one transducer so as to form a cavity, each acoustic reflector comprising an array of electrodes in the form of lines parallel with each other, each array comprising a subset of electrodes connected to a reference potential denoted mass defining a first connection type, and a subset of electrodes that are not connected to any potential, i.e. that have a floating connection defining a second connection type; at least one switching circuit configured to modify the distribution of the connections of at least one part of the electrodes of each array between the different connection types.Type: GrantFiled: December 27, 2019Date of Patent: February 6, 2024Assignees: THALES, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE, SOITEC SA, YNCREA HAUTS DE FRANCE ISEN LILLE, UNIVERSITE DE LILLE, ECOLE CENTRALE DE LILLE, UNIVERSITE POLYTECHNIQUE HAUTS-DE-FRANCEInventors: Thi Mai Pham Colomban, Claude Prévot, Paolo Martins, Anne-Christine Hladky-Hennion, Bertrand Dubus, Marianne Sagnard, Thierry Laroche, Sylvain Ballandras, Charles Croenne
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Patent number: 11802836Abstract: A process for detecting the sensitivity of one or more polymers and/or of one or more, mixtures of polymers to a compound, including the steps of exposing at least one lens-shaped micro-deposit, including the polymer(s) and/or the mixture(s) of polymers, to the compound, and detecting, by illuminating the surface of this micro-deposit, a change in the spatial distribution of the intensity of the light reflected or transmitted by this micro-deposit, linked to a variation in the dimensions and/or refractive index of this micro-deposit, under the effect of an interaction between the polymer(s) and/or the mixture(s) of polymers and the compound.Type: GrantFiled: June 1, 2018Date of Patent: October 31, 2023Assignees: Universite De Lille, Centre National De La Recherche ScientifiqueInventors: Alexis Vlandas, Julien Wengler, Sebastien Lamant, Vincent Senez
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Patent number: 11744863Abstract: Process for preparing a heat-treated pooled human platelet lysate, said process comprising the steps of: a) Providing a pooled human platelet lysate (p HPL), b) Heat-treating the pooled human platelet lysate at a temperature of 50° C. to 70° C. during 20 to 40 minutes, c) Purifying the heat-treated pooled human platelet lysate of step b).Type: GrantFiled: June 15, 2018Date of Patent: September 5, 2023Assignees: Centre Hospitalier Regional et Universitaire De Lille (CHRU), UNIVERSITE DE LILLE 2 DROIT ET SANTE, UNIVERSITE DU LITTORAL COTE D'OPALE, INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM), TAIPEI MEDICAL UNIVERSITYInventors: David Devos, Thierry Burnouf, Jean-christophe Devedjian, Ming-Li Chou, Flore Gouel
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Patent number: 11731127Abstract: Electroacoustic device having a transducer including a piezoelectric substrate, first and second electrodes of inverse polarity having respective first and second tracks provided on said substrate, the first and second tracks spiraling around a same center (C), the transducer being configured for generating a swirling ultrasonic surface wave in the substrate.Type: GrantFiled: March 15, 2016Date of Patent: August 22, 2023Assignees: CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE, UNIVERSITÉ DE LILLE, ECOLE CENTRALE DE LILLE, SORBONNE UNIVERSITEInventors: Michaël Aymeric Baudoin, Olivier Khalil Bou Matar-Lacaze, Antoine Jean-Pierre Riaud, Jean-Louis Pierre Thomas
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Publication number: 20230233483Abstract: The disclosure relates to the use of clofoctol in the prevention or treatment of a disease caused by a coronavirus, in particular Covid-19.Type: ApplicationFiled: June 8, 2021Publication date: July 27, 2023Applicants: Apteeus, Universite De Lille, Centre National De La Recherche Scientifique, Institut National De La Sante Et De La Recherche Medicale, Centre Hospitalier Universitaire De LilleInventors: Terence Beghyn, Benoît Deprez, Sandrine Belouzard, Priscille Brodin
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Publication number: 20230207300Abstract: A system and method for analyzing volatile organic compounds (VOCs) adsorbed on an adsorbent membrane, by low-temperature plasma and mass spectrometry (LTP-MS). The system includes a receptacle for receiving the adsorbent membrane, a low-temperature plasma ionizer configured to emit a plasma stream in a plasma emission direction, thereby ionizing the VOCs adsorbed by the membrane and forming a VOC-laden ionized gas, and a mass spectrometer for analyzing the ionized VOCs.Type: ApplicationFiled: May 20, 2021Publication date: June 29, 2023Applicants: UNIVERSITE DE LILLE, INSERM (INSTITUT NATIONAL DE LA SANTÉ ET DE LA RECHERCHE MÉDICALE), CENTRE HOSPITALIER REGIONAL ET UNIVERSITAIRE DE LILLE (CHRU)Inventors: Isabelle SALZET, Julien FRANCK, Michel SALZET, Flore HERVE
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Publication number: 20230157994Abstract: A method of treating COVID-19 in a patient. The patient may be in moderate to advanced stages of COVID-19 infection. The method includes administering to the patient a therapeutically effective amount of at least one antagonist or inhibitor of chemokine receptor CXCR4. The at least one antagonist or inhibitor of chemokine receptor CXCR4 is distinct from hydroxychloroquine.Type: ApplicationFiled: May 5, 2021Publication date: May 25, 2023Applicants: 4LIVING BIOTECH, UNIVERSITE DE BORDEAUX, CENTRE HOSPITALIER DE BORDEAUX, INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE - INSERM, INSTITUT PASTEUR DE LILLE, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE, UNIVERSITÉ DE LILLEInventors: Patrick BERGER, Isabelle DUPIN, Renaud PREVEL, Chloé JAMES, Pierre-Olivier GIRODET, Keren BISMUTH, Revital RATTENBACH, Jérôme BRETON, Francois TROTTEIN, Valentin SENCIO
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Publication number: 20230148181Abstract: A protein capable of converting chlorogenic acid into isochlorogenic acid. The protein includes or is an amino acid sequence SEQ ID No. 1, a sequence having at least 80% identity with this sequence or a fragment of this sequence. Also, a process for producing isochlorogenic acid from chlorogenic acid, which includes producing the protein and bringing it into contact with chlorogenic acid.Type: ApplicationFiled: March 12, 2021Publication date: May 11, 2023Applicants: UNIVERSITE DE LORRAINE, UNIVERSITE DE LILLE, CELLENGOInventors: Frédéric Jean BOURGAUD, Sissi MIGUEL, Aleksander SALWINSKI, Cindy SIGNE, Alain HEHN, Jean-Louis HILBERT, David GAGNEUL, Guillaume LEGRAND