Patents Assigned to UNIVERSITE DE LILLE
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Patent number: 11099205Abstract: A device for measuring an acceleration includes a vibrating accelerometer including: a semiconductor substrate forming a fixed frame of the accelerometer; a test weight of the same material as the substrate and connected to the fixed frame, movable translationally along at least one sensing axis of the vibrating accelerometer; a guide of the same material as the substrate, connected to the fixed frame and test weight, guiding the test weight in the direction of the sensing axis; a layer made of a piezoelectric semiconductor deposited on the substrate, the layer being tensilely prestrained; a resonator in the layer connected to the fixed frame, the resonator subjected to tension or compression in the direction of the sensing axis; and at least one transducer connected to the resonator, able to actuate the resonator, to keep the resonator oscillating and/or to detect an electrical signal generated by the resonator.Type: GrantFiled: May 9, 2017Date of Patent: August 24, 2021Assignees: CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE, UNIVERSITE DE LILLEInventors: Marc Faucher, Christophe Morelle
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Publication number: 20210257908Abstract: A continuous time digital signal processing (CT DSP) token includes a first signal indicating a change has occurred and a second signal indicating a direction of the change. An amplitude generation circuit operates to generate an amplitude value x in response to the token. A power estimation circuit processes the amplitude value x to generate a digital power signal in accordance with the formula: x2±2x+1.Type: ApplicationFiled: February 13, 2020Publication date: August 19, 2021Applicants: Universite de Lille, Centre National De La Recherche Scientifique, ISEN Yncrea Hauts-de-France, STMicroelectronics SAInventors: Angel de Dios GONZALEZ SANTOS, Andreas KAISER, Antoine FRAPPE, Philippe CATHELIN, Benoit LARRAS
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Patent number: 11090698Abstract: Method for increasing the ability of at least one droplet to slide over a medium. An ultrasonic surface wave is generated in the medium with a sufficient amplitude to cause the droplet to deform in an inertio-capillary eigen-vibration mode, thus decreasing the attachment of the droplet to the medium, so as to make it easier for the droplet to move under the effect of an external force, the amplitude of the ultrasonic surface wave being insufficient to cause the droplet to deform asymmetrically to the point that it moves in the absence of the external force in the direction of propagation of the ultrasonic surface wave.Type: GrantFiled: December 6, 2016Date of Patent: August 17, 2021Assignees: UNIVERSITÉ DE LILLE, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE, ECOLE CENTRALE DE LILLEInventors: Adrien Bussonniere, Olivier Bou Matar-Lacaze, Michaël Baudoin, Philippe Brunet
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Publication number: 20210214215Abstract: A nanostructure transfer method is provided. The method includes providing a first substrate (10) having thereon a plurality of nanostructures (12), the nanostructures (12) extending away from the first substrate (10). A solder material (14) is deposited on distal ends of the nanostructures (12). A second substrate (18) having thereon a first metal layer (20) is provided. The solder material (14) is bonded to the first metal layer (20), thereby attaching the nanostructures (12) to the second substrate (18). The attached nanostructures (12) are then released from the first substrate (10).Type: ApplicationFiled: August 29, 2019Publication date: July 15, 2021Applicants: THALES SOLUTIONS ASIA PTE LTD, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE, NANYANG TECHNOLOGICAL UNIVERSITY, UNIVERSITÉ DE LILLEInventors: Jianxiong Wang, Philippe Coquet, Beng Kang Tay
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Patent number: 11052025Abstract: Disclosed is a microemulsion of oil-in-water type including, preferably consisting of, by weight relative to the total weight of microemulsion: •70% to 94% of water, •1% to 15% of at least one hydrophobic fragrancing substance, •4% to 20% of at least one preferably volatile solvo-surfactant, and •0.1% to 15%, preferably 1% to 13%, of at least one hydrotropic agent or at least one surfactant selected from anionic surfactants, cationic surfactants, amphoteric surfactants and non-ionic surfactants. The solvo-surfactant is selected from monoalkylated glycerol derivatives of following formula (I): wherein the “alkyl” group is a linear or branched alkyl group including from 1 to 8 carbon atoms, and R and R? are each independently H or a linear or branched alkyl group including from 1 to 5 carbon atoms, with the proviso that R is different from R?, and mixtures thereof.Type: GrantFiled: June 1, 2017Date of Patent: July 6, 2021Assignees: CHANEL PARFUMS BEAUTE, UNIVERSITE DE LILLEInventors: Oriana Boucenna Verdier, Christian Mahe, Véronique Rataj-Nardello, Jean-Marie Aubry, Maxime Nollet, Raphaël Lebeuf
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Patent number: 11008217Abstract: The invention relates to an installation and a method for treating hydrogen sulphide. In particular, the invention relates to an installation and a method comprising at least one system for oxidizing hydrogen sulfide to sulfur (S) and water (H2O) with a solid reagent and at least one oxidizing system with an agent for oxidizing the solid reagent present in the reduced state, wherein the system of oxidizing the hydrogen sulfide to sulfur and the system for oxidizing the solid reagent, are so arranged that the hydrogen sulfide is not brought into contact with the agent oxidizing the solid reagent.Type: GrantFiled: May 19, 2017Date of Patent: May 18, 2021Assignees: CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE, UNIVERSITÉ DE LILLEInventors: Axel Lofberg, Jesus Guerrero
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Publication number: 20210107984Abstract: The disclosure relates to an antibody which is directed against galectin-9 and is an inhibitor of the suppressor activity of regulatory T lymphocytes, and also to the use of this antibody for the treatment of diseases associated with the suppressor activity of regulatory T lymphocytes, in particular the treatment of cancer.Type: ApplicationFiled: December 23, 2020Publication date: April 15, 2021Applicants: Universite de Lille, Centre National de la Recherche Scientifique, Institut Gustave Roussy, Cellvax, Universite Paris SaclayInventors: Nadira Delhem, Pierre Busson, Olivier Morales, Clement Barjon, Dhafer Mrizak, Claire Lhuillier, Rami Mustapha
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Patent number: 10961212Abstract: A method is for the preparation of furoic acid or of one of its derivatives of formula (I): in which R1, R2, R3 and R4 represent, independently of each other, a hydrogen atom, a linear or branched C1-C6 alkyl group, a —C(?O)—H group or a —COOH group, by heterogeneous catalytic oxidation of furfural or a derivative thereof of formula (II). The oxidation is carried out in the presence of a supported catalyst based on gold nanoparticles, and in a non-alkaline aqueous medium. A composition useful in the method includes at least furfural and supported gold nanoparticles.Type: GrantFiled: March 16, 2017Date of Patent: March 30, 2021Assignees: UNIVERSITÉ DE LILLE, ECOLE CENTRALE DE LILLE, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE, ALMA MATER STUDIORUM—UNIVERSITA' DI BOLOGNAInventors: Sébastien Paul, Francesco Santarelli, Robert Wojcieszak, Franck Dumeignil, Fabrizio Cavani
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Patent number: 10899838Abstract: The invention relates to an antibody which is directed against galectin-9 and is an inhibitor of the suppressor activity of regulatory T lymphocytes, and also to the use of this antibody for the treatment of diseases associated with the suppressor activity of regulatory T lymphocytes, in particular the treatment of cancer.Type: GrantFiled: June 5, 2015Date of Patent: January 26, 2021Assignees: Universite de Lille, Centre National de la Recherche Scientifique, Institut Gustave Roussy, Cellvax, Universite Paris-SaclayInventors: Nadira Delhem, Pierre Busson, Olivier Morales, Clement Barjon, Dhafer Mrizak, Claire Lhuillier, Rami Mustapha
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Patent number: 10842635Abstract: A temporo-mandibular prosthesis including a glenoid part and a condylar part intended to be articulated relative to the glenoid part. The glenoid part including a glenoid support made in a metallic material; and a glenoid insert made in a non-metal lie material, and defining a seat for a head of said condylar part to define said articulation, wherein the glenoid support defines a housing having an opening through which said glenoid insert is insertable into said housing, said opening opening on an external side (E) of said glenoid support, the glenoid support comprising a tab configurable in a passive position and in an active position in which said tab allows and forbids, respectively, the insertion and the extraction, respectively, of said glenoid insert into and out of said housing, respectively.Type: GrantFiled: February 14, 2018Date of Patent: November 24, 2020Assignees: Institut National De La Sante Et De La Recherche Medicale (INSERM), Centre Hospitalier Regional Universitaire De Lille, Universite De LilleInventor: Joel Ferri
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Patent number: 10844008Abstract: The present invention is directed to novel compounds of Formula (I), pharmaceutically acceptable salts or solvates thereof, and their use.Type: GrantFiled: November 30, 2018Date of Patent: November 24, 2020Assignees: UNIVERSITE DE LILLE 2 DROIT ET SANTE, CENTRE HOSPITALIER REGIONAL ET UNIVERSITAIRE DE LILLE (CHRU)Inventors: Patricia Melnyk, Patrick Vermersch, Pascal Carato, Bénédicte Oxombre-Vanteghem, Héléne Zephir, Marion Donnier-Marechal
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Patent number: 10807958Abstract: The present invention relates to the compound having Formula (I) or pharmaceutically acceptable salts or solvates thereof, and its use in treating and/or preventing a Tauopathy.Type: GrantFiled: June 15, 2018Date of Patent: October 20, 2020Assignees: INSERM (Institut National de la Sante et de la Recherche Medicale), UNIVERSITE DE LILLE 2 DROIT ET SANTEInventors: Nicolas Sergeant, Luc Buee, Patricia Melnyk, Marion Gay, Nicolas Le Fur
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Patent number: 10772884Abstract: The present invention relates to sulphate salts of N-(3-(4-(3-(diisobutylamino)propyl)piperazin-1-yl)propyl)-1H-benzo[d]imidazol-2-amine and pharmaceutically acceptable solvates thereof, preparation thereof, pharmaceutical compositions containing them and use of the same in the treatment and/or prevention of neurodegenerative diseases.Type: GrantFiled: August 27, 2019Date of Patent: September 15, 2020Assignees: Alzprotect, Universite De Lille 2 Droit Et Sante, INSERM (Institut National De La Sante Et De La Recherche)Inventors: Stéphane Burlet, Cécilia Estrella, Mathieu Barrier, Patricia Melnyk, Nicolas Sergeant, Luc Buee, Philippe Verwaerde
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Patent number: 10736937Abstract: The present invention relates to methods and pharmaceutical compositions for the treatment of bacterial superinfections post-influenza. In particular, the present invention relates to a method of treating a bacterial superinfection post-influenza in a subject in need thereof comprising administering the subject with a therapeutically effective amount of a flagellin polypeptide optionally in combination with at least one antibiotic.Type: GrantFiled: December 22, 2015Date of Patent: August 11, 2020Assignees: INSERM (INSTITUT NATIONAL DE LA SANTÉ ET DE LA RECHERCHE MÉDICALE), CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS), UNIVERSITÉ DE LILLE, INSTITUT PASTEUR DE LILLEInventors: Jean-Claude Sirard, Christophe Carnoy, François Trottein, Rémi Porte
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Patent number: 10712865Abstract: A computerized device having a man-machine input interface, a controller and a display. The controller being arranged to control the display according to a control value measured on the man-machine input interface at a first measuring frequency.Type: GrantFiled: September 19, 2017Date of Patent: July 14, 2020Assignees: Université De Lille, Inria Institut National De Recherche En Informatique Et En AutomatiqueInventors: Géry Casiez, Denis Efimov, Rosane Ushirobira, Stanislav Aranovskiy, Nicolas Roussel
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Publication number: 20200179247Abstract: An oil-in-water microemulsion including, in weight percentages: between 70% and 94% of water; between 1% and 15% of at least one perfumed hydrophobic substance; between 4% and 20% of at least one preferably volatile solvo-surfactant, which is a monoalkylated glycerol derivative of formula (I); and between 0.1% and 15% of at least one anionic surfactant and at least one alkyl glucoside as a hydrotropic agent. The microemulsion can therefore be used to produce a fine fragrance composition or a cosmetic or personal hygiene composition.Type: ApplicationFiled: May 31, 2018Publication date: June 11, 2020Applicants: CHANEL PARFUMS BEAUTE, UNIVERSITE DE LILLEInventors: Oriana BOUCENNA VERDIER, Véronique RATAJ-NARDELLO, Jean-Marie AUBRY, Grégory DOUYERE, Corentine MAINGUY
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Patent number: 10584383Abstract: The present invention relates to a method for predicting mortality of a test patient with chronic heart failure comprising based on detecting the expression level of one or more long non-coding RNAs (lncRNAs) selected from SEQ ID NOs 1 to 8. The present invention also relates to a method for predicting cardiac remodeling after myocardial infarction in a test patient based on detecting the expression level of one or more lncRNAs selected from SEQ ID NOs 1 to 8.Type: GrantFiled: March 18, 2015Date of Patent: March 10, 2020Assignees: MEDIZINISCHE HOCHSCHULE HANNOVER, INSTITUT NATIONAL DE LA SANTÉ ET DE LA RECHERCHE MÉDICALE (INSERM), UNIVERSITÉ DE LILLE 2 (LILLE 2)—UNIVERSITY OF LAW AND HEALTH, CENTRE HOSPITALIER UNIVERSITAIRE LILLE (CHU), INSTITUT PASTEUR DE LILLE (IPL)Inventors: Thomas Thum, Regalla Kumarswamy, Florence Pinet, Christophe Bauters, Pascal De Groote
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Patent number: 10561856Abstract: The system comprises: —a bundle of light fibers (11) connected to a light-emitting source (8), and both transmitting light inside the light fiber and emitting light toward a treatment volume (V), —a temperature-modifying system attached to the bundle of light fibers (11) to modify temperature in the treatment volume (V).Type: GrantFiled: November 25, 2014Date of Patent: February 18, 2020Assignees: INSERM (Institut National de la Santé et de la Recherche Médicale), Université de Lille 2 Droit et Santé, Centre Hospitalier Regional et Universitaire de Lille (CHRU)Inventors: Serge Mordon, Nacim Betrouni, Laurent Mortier
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Patent number: 10537569Abstract: The present invention relates to sulphate salts of N-(3-(4-(3-(diisobutylamino)propyl)piperazin-1-yl)propyl)-1H-benzo[d]imidazol-2-amine and pharmaceutically acceptable solvates thereof, preparation thereof, pharmaceutical compositions containing them and use of the same in the treatment and/or prevention of neurodegenerative diseases.Type: GrantFiled: December 22, 2016Date of Patent: January 21, 2020Assignees: ALZPROTECT, Universite de Lille 2 Droit et Saute, Inserm (Institut National De La Saute et de la Recherche MedicaleInventors: Stéphane Burlet, Cécilia Estrella, Mathieu Barrier, Patricia Melnyk, Nicolas Sergeant, Luc Buee, Philippe Verwaerde
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Patent number: 10519945Abstract: A method for generating a flow of fluid, implemented in a device including a membrane (2) provided with at least one hole (20) and elements (4) generating back-and-forth movements, wherein a flow is generated through the membrane by actuating the membrane, at least in the region of the at least one hole (20), according to a mode of deformation of the at least one hole, causing the at least one hole to open and close and disturbing the fluid in order to generate the flow. The device suitable for implementing the method is also described.Type: GrantFiled: October 24, 2014Date of Patent: December 31, 2019Assignees: UNIVERSITÉ DE LILLE, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE-CNRS, ECOLE CENTRALE DE LILLEInventors: Alain Merlen, Farzam Zoueshtiagh, Abdelkrim Talbi, Philippe Pernod, Christophe Frankiewicz