Patents Assigned to Universite de Rennes 1
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Patent number: 9019019Abstract: The invention concerns an oscillator generating a wave composed of a frequency of on the order of terahertz from a beat of two optical waves generated by a dual-frequency optical source. The oscillator includes a modulator the transfer function of which is non-linear for generating harmonics with a frequency of less than one terahertz for each of the optical waves generated by the dual-frequency optical source, an optical detector able to detect at least one harmonic for each of the optical waves generated by the dual-frequency optical source and transforming the harmonics detected into an electrical signal, a phase comparator for comparing the electrical signal with a reference electrical signal, and a module for controlling at least one element of the dual-frequency optical source with a signal obtained from the signal resulting from the comparison.Type: GrantFiled: May 24, 2011Date of Patent: April 28, 2015Assignees: Universite de Rennes 1, Centre National de la Recherche ScientifiqueInventors: Mehdi Alouini, Goulc'hen Loas, François Bondu, Marc Vallet, Marc-Olivier Brunel, Marco Romanelli
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Patent number: 8907671Abstract: Method to extract a diffusion direction from DW-MR signals, in which a magnetic field gradient qi is applied to a body part, a magnetic resonance signal Si is measured and a diffusion direction ?j is determined, wherein for a predetermined positive number m of diffusion direction(s) ?j, the signals Si are linked to the probability density function of the random vector X of water molecules displacements represented as a mixture of m probability density functions pXj of random vectors Xj characterizing the diffusion along ?j, the Xj being decomposed into a first component modelling directional variability of the water molecules displacements with ?j as mean direction, and into a second component modelling the length variability of the water molecules displacements along ?j.Type: GrantFiled: November 17, 2011Date of Patent: December 9, 2014Assignees: Universite de Rennes 1, Centre National de la Recherche Scientifique (CNRS), Institut National de Recherche en Informatique et en AutomatiqueInventors: Aymeric Stamm, Christian Barillot, Patrick Perez
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Publication number: 20140285803Abstract: An analysis system comprises a transmitting device (1.1) and a receiving device (1.2). The transmitting devices comprises means for illuminating an object (1.3), or a part of the object, by a first light beam (1.8) consisting of signals with two distinct frequencies and first orthogonal polarisation states. The receiving device comprises means (1.6) for detecting, in a second light beam with second polarisation states and resulting from the illumination of the object to be analysed by the first light beam, a signal at a beat frequency equal to a difference between the two frequencies of the first light beam; and means (1.7) for obtaining information relating to the depolarising or dichroic character of the object, or of the part of the object, according to the detection or not of a signal at the beat frequency.Type: ApplicationFiled: June 18, 2012Publication date: September 25, 2014Applicants: CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS), UNIVERSITE DE RENNES 1Inventors: Mehdi Alouini, Julien Fade
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Patent number: 8816101Abstract: The invention relates to a mixture comprising protolichesterinic acid or a salt thereof or a diastereoisomer thereof or a derivative thereof, and lichesterinic acid or a salt thereof or an enantiomer thereof or a derivative thereof, for use for stimulating pigmentation of the skin and/or of its appendages. The invention also relates to derivatives of lichesterinic acid of formula (A).Type: GrantFiled: March 4, 2011Date of Patent: August 26, 2014Assignees: Centre National de la Recherche Scientifique—CNRS, Universite de Rennes 1, Centre Hospitalier Universitaire PontchaillouInventors: Joel Boustie, Marie-Dominique Galibert-Anne, Francoise Lohezic-le-Devehat, Marylene Chollet-Krugler, Sophie Tomasi
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Patent number: 8798161Abstract: An encoding device for a flow of digital images comprises: a working memory (42) for already decoded image blocks data, a pilot (40), mounted to analyze an incidental flow of data of digital images, and arranged to determine data to be decoded of a current block, said data to be decoded being of the complete data type or of the parameters-data type, to store the complete data in the working memory (42) as already decoded image blocks data, and to call a decoding unit (48) with the parameters-data, the decoding unit (48) reacting to the reception of parameters-data by: selecting some already decoded image blocks, forming an approximation base, which borders the current block according to a selected rule, calculating an approximation of the current block, based on a linear algebraic function of the approximation base data, and storing in the working memory (42), for the current block, already decoded image blocks data derived from this approximation.Type: GrantFiled: December 1, 2009Date of Patent: August 5, 2014Assignees: INRIA Institut National de Recherche en Informatique et en Automatique, Universite de Rennes 1, Centre National de la Recherche Scientifique (C.N.R.S)Inventors: Christine Guillemot, Jean-Jacques Fuchs, Laurent Guillo
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Patent number: 8778911Abstract: A polyamine-depleted food compositions is provided for preparing foods, intended for humans or animals, for preventing or treating heart rate anomalies.Type: GrantFiled: January 10, 2007Date of Patent: July 15, 2014Assignee: Universite De Rennes 1Inventors: Jacques Moulinoux, Jean-Pie'rre Estebe
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Publication number: 20140154213Abstract: The present invention relates to a recombinant vector for expressing and secreting, by a propionibacterium, at least one eukaryotic peptide or protein of interest, comprising at least: under the control of at least one suitable promoter, at least one nucleic acid sequence encoding a propionibacterial signal peptide and, at least one nucleic acid sequence encoding said eukaryotic peptide or protein of interest; wherein said at least one nucleic acid sequence encoding a propionibacterial signal peptide is translationally fused to said at least one nucleic acid sequence encoding said eukaryotic peptide or protein of interest. The invention further relates to the uses of such a vector in the pharmaceutical field or for the large-scale production of peptides or proteins of interest.Type: ApplicationFiled: November 16, 2012Publication date: June 5, 2014Applicants: UNIVERSITE DE RENNES 1, INSTITUT NATIONAL DE LA RECHERCHE AGRONOMIQUE, INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM)Inventors: Gwenael JAN, Marie-Thérése DIMANCHE-BOITREL, Héléne FALENTIN, Charles HALOUZE
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Patent number: 8709747Abstract: The invention relates to compounds of formula (I) wherein the groups A and B represent independently from each other —CH?CH—, or —C?C—, the terms t, u, v, w represent, independently from each other, values ranging from 0 to 9, the groups Y1 and Y2 can represent independently from each other an alkyl group (linear, branched or substituted) carrying from 1 to 9 carbon atoms, the groups Z1, Z2, Z3, and Z4 can represent independently from each other a chemically reactive group W, such as OH, NH2, SH, the groups Z5 and Z6 represent independently from each other a hydrogen atom, silica nanoparticles functionalized by these compounds, and their use as drugs.Type: GrantFiled: December 7, 2010Date of Patent: April 29, 2014Assignees: Centre National de la Recherche Scientifique, Universite de Rennes 1, I.N.S.E.R.M. (Institut National de la Sante et de la Recherche Medicale), Universite Montpellier 2 Sciences et TechniquesInventors: David Brevet, Laurence Raehm, Mireille Blanchard-Desce, Olivier Mongin, Magali Gary-Bobo-Sable-Teychene, Marcel Garcia, Alain Morere, Jean-Olivier Durand
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Publication number: 20140046342Abstract: A system for aiding in the positioning of a medical instrument on the head of a patient, characterized in that it includes a means for predicting the location of a target intracranial area of the medical instrument, comprising a generic three-dimensional model of a head comprising a scalp and a generic target intracranial area, a three-dimensional working image of the scalp of the head of the patient, surface registration means suitable for establishing a registration transform from the scalp of the generic model toward the working image of the scalp of the head of the patient, a means for resampling the generic target intracranial area into a converted target area using with the registration transform, and a means for locating the target intracranial area of the patient from the locating of the converted target area, thereby enabling the positioning of the medical instrument on the head of the patient.Type: ApplicationFiled: January 25, 2012Publication date: February 13, 2014Applicants: INRIA INSTITUT NATIONAL DE RECHERCHE EN INFORMATIQUE ET EN AUTOMATIQUE, CENTRE HOSPITALIER UNIVERSITAIRE DE RENNES, UNIVERSITE DE RENNES 1Inventors: Pierre Hellier, Xavier Morandi, Benoît Combes, Charles Garraud, Sylvain Prima
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Patent number: 8621903Abstract: The invention relates to a continuous or instrumented indentation device for a material. The indentation device includes an indenter, a bearing means for the material to be indented, a means for moving the indenter and/or the bearing means for contacting the indenter with the material to be indented, and for pressing the indenter into the material, and a means for measuring the force and movement of the indenter when the indenter is pressed into the material. The bearing means includes a convex surface for receiving the material to be indented and is oriented towards the indenter so that the material is capable of bearing on the convex surface. The indenter may comprise a one-piece structure. The means for measuring the movement of the indenter when the indenter is pressed into the material includes at least three movement sensors angularly arranged at an equal distance about the indenter.Type: GrantFiled: September 15, 2009Date of Patent: January 7, 2014Assignee: Universite de Rennes 1Inventor: Gérard Mauvoisin
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Publication number: 20140000315Abstract: A process is provided for obtaining a glassy material that is optically transparent to infrared radiation. The process includes: a step of amorphization, by mechanosynthesis, of an assembly of starting elements including at least one metallic element and at least one chalcogenide element, making it possible to form an amorphous powder; a step of hot densification, in a mould of predetermined dimensions, of the amorphous powder, making it possible to obtain a glass; and heat treatment, carried out during or after the hot densification step, in which the glass is heated to a temperature at which a portion of the glass is converted from an amorphous state to a crystalline state, making it possible to obtain, after cooling, a glass-ceramic.Type: ApplicationFiled: December 6, 2011Publication date: January 2, 2014Applicants: UNIVERSITE DE RENNES 1, CNRSInventors: Laurent Calvez, Xiang Hua Zhang, Mathieu Hubert, Gaëlle Delaizir
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Publication number: 20130333519Abstract: The invention relates to a method for preparing a powder of an alloy based on uranium and molybdenum in a metastable ? phase, which comprises: a) putting at least one first reagent selected from uranium oxides and mixtures thereof, uranium fluorides and mixtures thereof, into contact with a second reagent consisting in molybdenum and a third reagent consisting in a reducing metal, the first, second and third reagents being in a divided form; b) reacting the reagents at a temperature?the melting temperature of the third reagent and under an inert atmosphere, whereby this reaction leads to the formation of the alloy comprising uranium and molybdenum in the form of a powder, for which the particles are covered with a reducing metal oxide or fluoride layer; c) cooling the so formed powder at a rate at least equal to 450° C./hour; and d) removing the reducing metal oxide or fluoride layer which covers the particles of the powder of the alloy comprising uranium and molybdenum.Type: ApplicationFiled: December 23, 2011Publication date: December 19, 2013Applicant: UNIVERSITE DE RENNES 1Inventors: Jerome Allenou, Meryl Brothier, Francois Charollais, Xaviere Iltis, Olivier Tougait, Mathieu Pasturel, Henri Noel
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Publication number: 20130336833Abstract: The invention relates to a powder of an alloy based on uranium and molybdenum in a metastable ? phase, which is formed of particles which have an elongation index at least equal to 1.1, a non-zero closed porosity value and which are composed of grains having a molybdenum content, for which the variations within the same grain are of at most 1% by mass. It also relates to a method allowing preparation of this alloy powder as well as to the use of said powder for manufacturing nuclear fuels and targets for producing radioisotopes. Applications: Manufacturing of nuclear fuels, notably for experimental nuclear reactors; manufacturing of targets for producing radioisotopes, notably for the medical industry.Type: ApplicationFiled: December 23, 2011Publication date: December 19, 2013Applicants: COMMISSARIAT A L'ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES, UNIVERSITE DE RENNES 1Inventors: Jerome Allenou, Francois Charollais, Meryl Brothier, Xaviere Iltis, Olivier Tougait, Mathieu Pasturel, Henri Noel
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Patent number: 8592616Abstract: Embodiments of the present disclosure include compounds including a M6 based cluster core with luminescent properties, methods for producing these compounds, as well as to luminescent materials with liquid crystalline properties including these compounds.Type: GrantFiled: November 23, 2010Date of Patent: November 26, 2013Assignees: Université de Rennes 1, C.N.R.S.Inventors: Yann Molard, Stéphane Cordier, Maria de los Angeles Amela Cortes, Frédérick Dorson
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Patent number: 8563588Abstract: Imidazolone derivatives, as medicaments, of formula wherein: R1?H, C1 to C5 alkyl, aryl or a 5- or 6-membered heterocyclic group; Ar1=optionally substituted aryl or an aromatic heterocycle; R?R2—S—, R3—HN—, R4COHN or Ar2, with R2=a C1-C5 alkyl, vinyl or vinyl(C1-C5)alkyl, nitrile or nitrile(C1-C5)alkyl, aryl or benzyl radical, which are optionally substituted; R3=the meanings given above and H; Ar2=substituted or unsubstituted aryl.Type: GrantFiled: August 1, 2008Date of Patent: October 22, 2013Assignees: Universite de Rennes 1, Centre National de la Recherche Scientifique (C.N.R.S.)Inventors: Francois Carreaux, Jean-Pierre Bazureau, Steven Renault, Laurent Meijer, Olivier Lozach
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Patent number: 8535643Abstract: Fluorescent chemical compound composed of an n-generation dendrimer, n being a non-zero integer, exhibiting: —at least one central nucleus (N) with a valency of m, selected from the group consisting of—at least one first, non-chromophoric unit (X) with a valency of m?, and—at least one second unit (Y) which exhibits two-photon absorption properties, with a valency of m?.Type: GrantFiled: January 10, 2007Date of Patent: September 17, 2013Assignees: Universite de Rennes 1, CNRSInventors: Mireille Blanchard-Desce, Martinus Werts, Olivier Mongin, Jean-Pierre Majoral, Anne-Marie Caminade, Rama Krishna Thatavarthy
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Publication number: 20130141174Abstract: The invention concerns an oscillator generating a wave composed of a frequency of on the order of terahertz from a beat of two optical waves generated by a dual-frequency optical source (10). The oscillator comprises: a modulator (12) the transfer function of which is non-linear for generating harmonics with a frequency of less than one terahertz for each of the optical waves generated by the dual-frequency optical source, an optical detector (14) able to detect at least one harmonic for each of the optical waves generated by the dual-frequency optical source and transforming the harmonics detected into an electrical signal, a phase comparator (15) for comparing the electrical signal with a reference electrical signal, means (16) for controlling at least one element of the dual-frequency optical source with a signal obtained from the signal resulting from the comparison.Type: ApplicationFiled: May 24, 2011Publication date: June 6, 2013Applicants: CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE, UNIVERSITE DE RENNES 1Inventors: Mehdi Alouini, Goulc'hen Loas, François Bondu, Marc Vallet, Marc-Olivier Brunel, Marco Romanelli
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Patent number: 8450342Abstract: The invention relates to trisubstituted or tetrasubstituted imidazo[4,5b]pyridines, to their uses as well as to a process for manufacturing them. The compounds of the invention are imidazo[4,5b]pyridines. The first general synthesis of 3,5,7 imidazo[4,5b]pyridines is disclosed in the description. The invention founds application, in particular, in the pharmaceutical field.Type: GrantFiled: February 19, 2010Date of Patent: May 28, 2013Assignees: Centre Nationale de la Recherche Scientifique, Universite de Rennes 1, Universite Paris DescartesInventors: Laurent Meijer, Karima Bettayeb, Herve Galons, Luc Demange, Nassima Oumata
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Publication number: 20130116458Abstract: The subject matter of the invention is a process for synthesizing a saturated long-chain o.,0)-amino ester (acid) obtained in a first step by cross-metathesis between an acrylic first compound and a monounsaturated second compound comprising at least one nitrile, acid or ester trivalent function, one of these compounds comprising a nitrile function and the other an acid or ester function, in the presence of a ruthenium carbene metathesis catalyst, and in a second step by hydrogenation of the monounsaturated nitrile ester (acid) obtained in the presence of the metathesis catalyst of the preceding stop, acting as a hydrogenation catalyst.Type: ApplicationFiled: May 9, 2011Publication date: May 9, 2013Applicants: ARKEMA FRANCE, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE, UNIVERSITE DE RENNES 1Inventors: Jean Luc Couturier, Jean Luc Dubois, Xiaowei Miao, Cedric Fischmeister, Christian Bruneau, Pierre Dixneuf
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Publication number: 20130108584Abstract: The present invention relates to a recombinant vector for expressing and secreting, by a propionibacterium, one or more amino acid sequences of interest, wherein said vector comprises at least: under the control of at least one suitable promoter, at least one nucleotide sequence coding for a propionibacteria signal peptide and, in translational fusion with said nucleotide sequence, one or more nucleotide sequences coding for said amino acid sequence or sequences of interest. The invention further relates to the uses of such a vector in the pharmaceutical field or for the large-scale production of peptides or proteins of interest.Type: ApplicationFiled: May 12, 2011Publication date: May 2, 2013Applicants: UNIVERSITE DE RENNES 1, INSTITUT NATIONAL DE LA RECHERCHE AGRONOMIQUE, INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM)Inventors: Gwenael Jan, Marie-Thérèse Dimanche-Boitrel, Hélène Falentin