Patents Assigned to Universite Paul Sabatier (Toulouse III)
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Publication number: 20100247751Abstract: A process for manufacturing a thermally and/or electrically conducting solid, in which: at least one doped aqueous dispersion is prepared, the dispersion including a mica powder and at least one dopant powder, these being dispersed in a non-ionic aqueous liquid, each dopant being chosen from graphites, with the exception of unexpanded expandable graphites, the mica representing at least 5% by weight of the solid matter of the dispersion, the dopant(s) representing 1 to 95% by weight of the solid matter of the dispersion and a proportion of each dopant being chosen depending on the desired thermal and electrical conductivities; each doped aqueous dispersion undergoes a forming operation, the proportion by weight of solid matter in the dispersion having been chosen so as to obtain, in the case of the doped aqueous dispersion, a viscosity compatible with the forming technique used; and the doped aqueous dispersion is left to undergo form consolidation, by at least the evaporation of the aqueous phase of the dispType: ApplicationFiled: November 20, 2008Publication date: September 30, 2010Applicants: UNIVERSITE PAUL SABATIER TOULOUSE III, INSTITUT NATIONAL POLYTECHNIQUE DE TOULOUSEInventors: Pierre Gros, Jacques Prosdocimi
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Publication number: 20100092829Abstract: A gas electrode includes a plurality of stacked layers (2, 3, 4), wherein the first layer (2) is in contact with a solid substrate (1) while the last layer (4) has a free outer surface to be contacted with a gas, each layer being made of at least one mixed oxide selected from the group including perovskites and Ruddlesden-Popper phases, the micro-structure of the first layer (2) being different from that of the last layer (4), the porosity of the different layers (2, 3, 4) increasing from the first layer (2) towards the last layer (4), and the different layers stacked on each other defining a network of a solid interconnected material between the free outer surface of the last layer (4) and the solid substrate with a total thickness higher than 1 ?m. A method for making such an electrode and its use in an electrochemical cell are disclosed.Type: ApplicationFiled: December 19, 2007Publication date: April 15, 2010Applicants: UNIVERSITE PAUL SABATIER TOULOUSE III, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (C.N.R.S.)Inventors: Marie-Laure Fontaine, Fabrice Mauvy, Pascal Lenormand, Jean-Marc Bassat, Florence Ansart, Jean-Claude Grenier
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Publication number: 20100065743Abstract: The invention relates to the use of a material having a spinel ferrite/iron monoxide structure as a sensitive material in the form of a thin film for the bolometric detection of infrared radiation, the chemical composition of said structure, excluding doping agents that may be present, having empirical formula (I): (Fe1?zMz)xO, where x is strictly less than 1 and strictly greater than 0.75. The invention also relates to a bolometric device for infrared radiation detection and infrared imaging, comprising at least one sensor provided with a sensitive element in the form of a thin film as defined above.Type: ApplicationFiled: June 11, 2009Publication date: March 18, 2010Applicants: COMMISSARIAT A L'ENERGIE ATOMIQUE, UNIVERSITE PAUL SABATIER TOULOUSE III, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUEInventors: Philippe TAILHADES, Lionel PRESMANES, Corinne BONNINGUE, Bruno MAUVERNAY, Jean-Louis OUVRIER-BUFFET, Agnes ARNAUD, Wilfried RABAUD
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Patent number: 7662270Abstract: The invention relates to an electrochemical method and reactor in which at least one electrochemical reaction compartment (5, 6) comprises a plurality of microchannels whose grooves have a cross section of at least partially curved contour with a radius of curvature greater than 30 ?m and an area of between 2500 ?m2 and 20000 ?m2. Application to the synthesis of diastereoisomers by continuous regeneration of NADH or NADPH.Type: GrantFiled: November 18, 2005Date of Patent: February 16, 2010Assignees: Universite Paul Sabatier Toulouse III, Centre National de la Recherche Scientifique (C.N.R.S.)Inventors: Theodore Tzedakis, Cheikhou Kane, Anne Launay
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Publication number: 20090170142Abstract: The present invention pertains to the use of a PptT protein, as a target for screening compounds for identifying those having an antibiotic activity, especially against a pathogenic bacterium containing mycolic acids. The invention also concerns an in vitro screening process for identifying compounds having an antibiotic activity, by measuring the activity of a PptT protein in the presence or absence of said compounds.Type: ApplicationFiled: December 8, 2006Publication date: July 2, 2009Applicants: CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE, UNIVERSITE PAUL SABATIER-TOULOUSE IIIInventors: Christian Chalut, Christophe Guilhot
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Publication number: 20090137532Abstract: The invention relates to novel aldolase-inhibiting compounds that can be advantageously used as medicaments (in therapeutic doses), especially for treating certain cancers, due to the inhibition efficacy thereof. An inventive compound corresponds to general formula (I) wherein the aldehyde group (—CHO) and the phenol group (—OH) are linked to two carbon atoms adjacent to the same aromatic chain, i.e., the first aromatic chain, and R is a phosphate group or a phosphate group mimetic linked to a carbon atom of the second aromatic chain.Type: ApplicationFiled: November 6, 2008Publication date: May 28, 2009Applicants: VALORISATION-RECHERCHE, LIMITED PARTNERSHIP, UNIVERSITE PAUL SABATIER TOULOUSE IIIInventors: Chantal Dax, Casimir Blonski, Laurent Azema, Jurgen Sygusch
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Patent number: 7528211Abstract: The invention concerns a method for preparing poly(-hydroxy acids), the polymerization reaction being performed in controlled manner in the presence of a catalytic system including a base, said base being a 5- or 6-membered aromatic heterocycle comprising at least one endocyclic nitrogen atom, provided that when the base is used alone in the catalytic system, it does not represent pyridine, 2-methylpyridine, 2,6-dimethylpyridine or 2-methoxypyridine. The invention also concerns poly(-hydroxy acids) of formula (IV). Finally, the invention concerns the use of a poly(-hydroxy acid), obtainable by the inventive method, for vectoring active principles or for making biomaterials.Type: GrantFiled: April 6, 2007Date of Patent: May 5, 2009Assignees: Isochem, Centre de la Recherche Scientifique (CNRS), Universite Paul Sabatier Toulouse IIIInventors: Didier Bourissou, Olivier Thillaye Du Boullay, Emmanuel Marchal, Bianca Martin-Vaca
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Patent number: 7470821Abstract: The invention relates to novel aldolase-inhibiting compounds that can be advantageously used as medicaments (in therapeutic doses), especially for treating certain cancers, due to the inhibition efficacy thereof. An inventive compound corresponds to general formula (I) wherein the aldehyde group (—CHO) and the phenol group (—OH) are linked to two carbon atoms adjacent to the same aromatic chain, i.e., the first aromatic chain, and R is a phosphate group or a phosphate group mimetic linked to a carbon atom of the second aromatic chain.Type: GrantFiled: June 29, 2004Date of Patent: December 30, 2008Assignees: Valorisation-Recherche, Limited Partnership, Universite Paul Sabatier Toulouse IIIInventors: Chantal Dax, Casimir Blonski, Laurent Azema, Jurgen Sygusch
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Publication number: 20080248071Abstract: The invention concerns particles consisting essentially of fibers of an organogelling substance in the form of xerogel (dry gel), the fibers being essentially oriented in a common direction and randomly aligned around the longest fiber. The organogelling substance is preferably 1,3:2,4-di-O-benzylidene-D-sorbitol. Said particles, which are in the form of spindles, have interesting optical properties; they have a total light transmittance higher than 0.80, with a diffuse transmittance higher than the specular transmittance. The invention also concerns a method for preparing said particles by solvent evaporation process, by solvent diffusion/evaporation process or by shearing process. The invention finally concerns active particles consisting of said particles whereon is immobilized a dermocosmetically active principle, a dermocosmetic composition comprising said particles or said active particles and a cosmetic treatment method which consists in applying on the skin said dermocosmetic composition.Type: ApplicationFiled: September 29, 2006Publication date: October 9, 2008Applicants: Pierre Fabre dermo-Cosmetique, Universite Paul Sabatier Toulouse III, Centre National De La Recheche ScientifiqueInventors: Anne Doat, Emile Perez, Isabelle Rico-Lattes, Pascal Bordat
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Publication number: 20080090786Abstract: The invention relates to a process for the specific fluorination of the phosphorus atom of a phosphonocinnamic compound of the general formula (II) or (II?): X being selected from: an oxygen atom, a sulfur atom, R1, R2, R3, R4, R5 and R6 being selected from: H, an alkyl group, an aryl group, OH, O-alkyl, S-alkyl, NH2, NH-alkyl, N-(alkyl)2; R7, being selected from: H, an alkyl group, an aryl group, a silyl group; R8 being selected from: H, an alkyl group, an aryl group, TBDPS representing a tert-butyldiphenylsilyl group; in said process said compound is reacted with a fluorinating agent comprising a complex formed between a tertiary amine and hydrogen fluoride. The invention extends also to novel fluorinated compounds so prepared and to therapeutic compositions comprising such fluorinated compounds.Type: ApplicationFiled: September 26, 2005Publication date: April 17, 2008Applicants: CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (C. N, UNIVERSITE PAUL SABATIER TOULOUSE IIIInventors: Michel Baltas, Florence Bedos-Belval, Hubert Duran, Caroline Lapeyre, Anne-Elisabeth Negre-Salvayre
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Publication number: 20080008712Abstract: The present invention relates to a peptide sequence characterized in that it comprises or is constituted by a fragment of at least approximately 10 amino acids originating from the following sequence SEQ ID NO: 1: TPVQNKRRRSpVTPPEEQQE SEQ ID NO: 1 in which the serine residue in position 10 is phosphorylated, said above-mentioned fragment containing said phosphorylated serine residue. The present invention also relates to a polyclonal or monoclonal antibody capable of recognizing a peptide sequence as defined above.Type: ApplicationFiled: June 8, 2004Publication date: January 10, 2008Applicants: CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE, UNIVERSITE DE RENNES 1, UNIVERSITE PAUL SABATIER TOULOUSE IIIInventors: Bernard Ducommun, Bernard Monsarrat, Claude Prigent
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Publication number: 20070009507Abstract: The invention concerns citrulline polypeptide derived from fibrin useful for diagnosing or treating rheumatoid arthritis.Type: ApplicationFiled: January 26, 2006Publication date: January 11, 2007Applicant: UNIVERSITE PAUL SABATIER-TOULOUSE IIIInventors: Guy Serre, Mireille Sebbag
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Patent number: 5324821Abstract: Method of preparing a lipoprotein modified by incorporation of at least one lipophilic active substance other than a triglyceride, characterized by incorporation of said active substance into an emulsion of a lipid phase in a continuous aqueous phase, by adding to the emulsion, with stirring, an original lipoprotein and at least one lipid transfer protein, allowing the mixture to incubate, and, using known methods, isolating the lipoprotein into which the active substance is incorporated; a lipoprotein thus obtained, and pharmaceutical or cosmetic composition containing such a modified lipoprotein.Type: GrantFiled: May 6, 1992Date of Patent: June 28, 1994Assignees: Universite Droit et Sante Lille II, Universite Paul Sabatier Toulouse IIIInventors: Gilles Favre, Patrick Duriez, Francoise Monard, Samadi-Baboli Medhi, Georges Soula, Jean-Charles Fruchart
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Patent number: 4840925Abstract: A manganite type composition of the formulaMn.sub.3-x-y-z Ni.sub.x Co.sub.y M.sub.z O.sub.4 (I)wherein M is at least one metal selected from Cu, Zn and Cd, y and z range from 0 to 1, and (x+y+z) is lower than 2. This composition can also contain a doping agent. The composition is either a particulate composition wherein at least 90% of the particles have a regular form and a size lower than 5 .mu.M or a ceramic material having a density greater than 94% of the theoretical density. The composition is useful in the production of thermistors.Type: GrantFiled: June 4, 1986Date of Patent: June 20, 1989Assignee: Universite Paul Sabatier (Toulouse III)Inventors: Abel C. Rousset, Guy Boissier, El Hadj Jabry, Jean-Pierre Caffin
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Patent number: 4808327Abstract: Particulate magnetic oxide compositions based on iron oxide (III) and oxide of at least one bivalent metal selected among cobalt, iron, copper, zinc, magnesium, nickel, manganese and cadmium, characterized in that said compositions contain additionally in the form of an oxide from 0.2 to 5% by weight calculated on the total weight at least one additive or substituent selected among alkali metals, alkaline-earth metals, boron, the elements of columns 3, 4 and 5 of the periodical classification of elements having a molecular mass higher than 26, the transition metals 3d and 4d other than those already mentioned, and the rare earths, with the proviso that when an alkali metal or tin is present, at least another additive or substituent is also present, and in that said compositions have a structure of the lanucar spinel type; the preparation and application thereof are also disclosed.Type: GrantFiled: June 1, 1987Date of Patent: February 28, 1989Assignees: Centre National de la Recherche Scientifique (CNRS), Universite Paul Sabatier (Toulouse III)Inventors: Abel Rousset, Christiane B. Salvaing, Paul Mollard, Michel Gougeon, Philippe Tailhades
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Patent number: 4738267Abstract: The invention relates to a pressure sensor implanted into the skull to emit an electrical signal representing the intra-cranial pressure; this sensor is of the type which includes on one hand a test body (1) comprising a deforming diaphragm (3) and of an undeforming guard ring (2), and on the other hand a deformation detector (5) associated with the diaphragm; the test body (1) is made of an integral piece, in particular plastic, and has a continuous front side (1a) which preferably is planar; the mechanical and dimensional properties of the constituent plastic are matched in such a manner that under the maximum pressure of 30 kilopascals, the diaphragm deflection is within a predetermined range; within this range, the dura mater pressed by the sensor transmits faithfully the intracranial pressure with adequate sensitivity to employ a resistive type transducer which simultaneously is simple, rugged compact and economical.Type: GrantFiled: March 24, 1986Date of Patent: April 19, 1988Assignee: Universite Paul Sabatier (Toulouse III)Inventors: Yves Lazorthes, Gil Clemente, Bernard Aragon