Patents Assigned to Universite Paul Sabatier (Toulouse III)
  • Publication number: 20150133290
    Abstract: A method for preparing a novel hydrogel including silico-metallic mineral particles of the formula (Six(Si-A)1-x)4M3O11.n?H2O, in which: x is a real number in the range [0.75; 1], A denotes a group selected from methyl and hydrocarbon groups including at least one heteroatom, and M is a metal selected from the group consisting of magnesium, cobalt, zinc, copper, manganese, iron, nickel and chromium, wherein a coprecipitation reaction is carried out in an aqueous medium between: at least one metal salt of the metal M, sodium metasilicate, Na2OSiO2, and at least one water-soluble oxysilane of formula (I): in which R1, R2 and R3 are selected from hydrogen and linear alkyl groups including 1 to 3 carbon atoms.
    Type: Application
    Filed: December 19, 2012
    Publication date: May 14, 2015
    Applicants: CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (C.N. R.S.), UNIVERSITE PAUL SABATIER TOULOUSE III
    Inventors: Christophe Le Roux, Francois Martin, Pierre Micoud, Angela Dumas
  • Publication number: 20150037819
    Abstract: A method for determining the quantity of anti-HLA antibodies of a liquid medium containing antibodies.
    Type: Application
    Filed: February 15, 2013
    Publication date: February 5, 2015
    Applicants: UNIVERSITE PAUL SABATIER TOULOUSE III, INVIVOGEN, CENTRE HOSPITALIER UNIVERSITAIRE DE TOULOUSE
    Inventors: Antoine Blancher, Nicolas Congy, Jean-Gerard Tiraby, Daniel Drocourt
  • Publication number: 20150008356
    Abstract: A process for preparing a magnetic talcous composition including mineral particles, referred to as magnetic talcous particles, having a non-zero magnetic susceptibility, in which, during an oxidative contacting step, talcous particles chosen from the group formed from 2:1 lamellar silicates having a zero electric charge are brought into contact with particles including at least one magnetic iron oxide chosen from the group formed from magnetite and maghemite, the magnetic particles having a mean equivalent diameter of between 1 nm and 50 nm. A magnetic talcous composition including mineral particles, referred to as magnetic talcous particles, having a non-zero magnetic susceptibility, at least 20% by weight of talcous particles and at least 0.5% by weight of magnetic particles is also described.
    Type: Application
    Filed: December 21, 2012
    Publication date: January 8, 2015
    Applicants: UNIVERSITE PAUL SABATIER TOULOUSE III, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (C.N.R.S.)
    Inventors: Francois Martin, Pierre Micoud, Angela Dumas, Christophe Le Roux, Emmanuel Gardes
  • Publication number: 20140374343
    Abstract: A device for purifying liquid wastewater, includes: a container suitable for retaining a granulate consisting of solid particles, and for enabling the contact between the solid particles of the granulate and the liquid wastewater flowing in the container between: an inlet for the liquid wastewater to flow into the container, and an outlet for substantially decontaminated water to flow out of the container; a community of microorganisms extending so as to be in contact with the solid particles of the granulate; at least one live benthic invertebrate whose mean size is greater than 250 ?m and which is distributed in the granulate; and at least one live benthic invertebrate whose mean size is from 50 ?m to 250 ?m and which is distributed in the granulate, characterized in that the community of macrobenthic organism and meiobenthic organism species includes a proportion of 60% to 80% of invertebrate detrivorous organisms.
    Type: Application
    Filed: January 8, 2013
    Publication date: December 25, 2014
    Applicants: INSTITUT NATIONAL POLYTECHNIQUE DE TOULOUSE, UNIVERSITE PAUL SABATIER (TOULOUSE III), CENTRE NATIONAL DE LA RECHERCHE SCIENTIQUE (C.N.R.S.)
    Inventors: Magali Gerino, Philippe Vervier, Jose Miguel Sanchez Perez, Laury Gauthier
  • Patent number: 8895518
    Abstract: The present invention relates to an intermolecular association complex of an amphiphilic carrier and an active principle G, having the following general formula (I), as well as to the compositions containing same, to the uses thereof, particularly as a drug, and to the method for preparing same.
    Type: Grant
    Filed: October 4, 2010
    Date of Patent: November 25, 2014
    Assignees: Centre National de la Recherche Scientifique, Universite Paul Sabatier Toulouse III
    Inventors: Cécile Bize, Muriel Blanzat, Emile Perez, Isabelle Rico-Lattes
  • Patent number: 8877085
    Abstract: A piezoelectric and/or pyroelectric composite solid hybrid material, includes: a solid dielectric matrix, a filler of at least one inorganic piezoelectric and/or pyroelectric material, wherein the filler includes filiform nanoparticles distributed throughout the volume of the solid dielectric matrix with an amount by volume of less than 50%, and in that the main directions of elongation of the filiform nanoparticles of the inorganic filler distributed in the dielectric matrix have a substantially isotropic distribution in the solid dielectric matrix.
    Type: Grant
    Filed: December 3, 2010
    Date of Patent: November 4, 2014
    Assignee: Universite Paul Sabatier Toulouse III
    Inventors: Jean-Fabien Capsal, Charlotte David, Eric Dantras, Colette Lacabanne
  • Patent number: 8865408
    Abstract: The present invention relates to a method for diagnosing aggressiveness and/or genetic instability of a cancer in a patient from a cancer sample of the patient. The method includes measuring in vitro the expression level of the POLQ gene and the expression level of a control gene in the patient cancer sample, calculating an expression level ratio of the expression level of POLQ to the expression of the control gene in the patient cancer sample, comparing the expression level ratio to a corresponding threshold value, and diagnosing cancer aggressiveness and genetic instability if the POLQ expression level ratio is superior to a corresponding threshold value. Dedicated microarrays and kits are also described, as well as a method of selecting a suitable treatment.
    Type: Grant
    Filed: May 18, 2011
    Date of Patent: October 21, 2014
    Assignees: Centre National de la Recherche Scientifique (CNRS), Universite Paul Sabatier Toulouse III, Institut Claudius Regaud
    Inventors: Christophe Cazaux, Jean-Sébastien Hoffmann, Jean-Christophe Bourdon, Alice Machado Da Silva, Henri Roche
  • Publication number: 20140205528
    Abstract: A process for preparing a composition including synthetic mineral particles, in which a hydrogel which is a precursor of the synthetic mineral particles is prepared via a coprecipitation reaction between at least one compound including silicon, and at least one compound including at least one metal element, characterized in that the coprecipitation reaction takes place in the presence of at least one carboxylate salt of formula R2—COOM? in which: —M? denotes a metal chosen from the group made up of Na and K, and —R2 is chosen from H and alkyl groups including fewer than 5 carbon atoms. A composition including synthetic mineral particles which is obtained by such a process is also described.
    Type: Application
    Filed: July 6, 2012
    Publication date: July 24, 2014
    Applicants: UNIVERSITE PAUL SABATIER (TOULOUSE III), CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (C.N.R.S.)
    Inventors: Christophe Le Roux, Francois Martin, Pierre Micoud, Angela Dumas
  • Patent number: 8778273
    Abstract: Device for emitting a plasma jet at ambient pressure and temperature, includes an electric-field generator for generating discharges between an anode assembly and a cathode assembly. The cathode assembly defines an inter-cathode dielectric space that extends inside the cathode assembly and is opposite at least one cathode surface of the cathode assembly, and has at least one cathode opening extending outside the inter-cathode space, the cathode opening being defined by at least one active edge of the cathode surface, the active edge(s) extending in a cathode opening plane. The anode assembly includes at least one pointed portion that is oriented toward the outside of the inter-cathode space and is laterally and deeply placed relative to the cathode opening. The pointed portion extends up to the cathode opening plane, for causing a plasma jet emission that is spontaneously sprayed in a predetermined direction toward the outside of the inter-cathode space.
    Type: Grant
    Filed: June 23, 2010
    Date of Patent: July 15, 2014
    Assignees: Universite Paul Sabatier Toulouse III, Centre National de la Recherche Scientifique
    Inventors: Nofel Merbahi, Mohammed Yousfi, Olivier Eichwald
  • Publication number: 20140186845
    Abstract: The present invention relates to methods for determining the expression level of a gene of interest in a nucleic acid sample by RT-qPCR. More specifically, procedures for determining the impact of a gDNA contamination on the measured total signal have been developed allowing the correction of the signal originating from the above said gDNA. A further aspect of the invention refers to a mean by which the sensitivity qPCR primers toward gDNA can be determined.
    Type: Application
    Filed: June 14, 2012
    Publication date: July 3, 2014
    Applicants: UNIVERSITE PAUL SABATIER - TOULOUSE III, INSERM (Institut National de la Sante et de la Recherche Medicale)
    Inventors: Henrik Laurell, Mikael Kubista, Jason Iacovoni
  • Publication number: 20140186366
    Abstract: The present invention relates to an in vitro method for determining whether a patient having hyperplastic polyps is at risk of developing a colonic neoplasia after resection of said hyperplastic polyps, said method comprising the step of determining the level of progastrin expression in a tissue sample of a hyperplastic polyp obtained from said patient.
    Type: Application
    Filed: May 31, 2012
    Publication date: July 3, 2014
    Applicants: INSERM (INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE), UNIVERSITE PAUL SABATIER - TOULOUSE III
    Inventors: Catherine Seva, Catherine Do, Audrey Ferrand, Julien Palasse, Marie-Bernadette Delisle
  • Patent number: 8710073
    Abstract: The present invention relates to bi-substrate inhibitor molecules combining (i) a pyridine, pyridinium or dihydropyridine-type structure allied to active metabolites of isoniazide, or related structures, and (ii) a hydrophobic substituent. The invention also relates to the method for preparing said molecules, to the pharmaceutical compositions containing said molecules, and to the use thereof as inhibitors of enoyl reductase for the preparation of a drug, especially an anti-infective drug for the treatment of tuberculosis.
    Type: Grant
    Filed: February 6, 2009
    Date of Patent: April 29, 2014
    Assignees: Centre National de la Recherche Scientifique (C.N.R.S.), Universite Paul Sabatier Toulouse III
    Inventors: Jean Bernadou, Vania Bernardes-Genisson, Tamara Delaine, Annaïck Quemard
  • Patent number: 8652703
    Abstract: The present invention relates to a method for manufacturing a metal-oxide-based ceramic, including, in order, the step of inserting, into a flash sintering device, a nanocrystalline powder comprising crystallites and crystallite agglomerates of a ceramic of formula, Zr1-xMxO2, where M is chosen from yttrium, scandium and cerium, or Ce1-xM?xO2, where M? is chosen from gadolinium, scandium, samarium and yttrium, where x lies between 0 and 0.2, the powder having an average crystallite size of between 5 and 50 nm, an average crystallite agglomerate size of between 0.5 and 20 ?m, and a specific surface area of between 20 and 100 m2/g. The invention further includes the step of flash sintering the powder by applying a pressure of between 50 and 150 MPa, at a temperature of between 850° C. and 1400° C., for a time of between 5 and 30 minutes.
    Type: Grant
    Filed: June 16, 2010
    Date of Patent: February 18, 2014
    Assignees: Electricite de France, Universite Paul Sabatier Toulouse III
    Inventors: Mohsine Zahid, Mathilde Rieu, Claude Estournes, Pascal Lenormand, Florence Ansart
  • Publication number: 20140044969
    Abstract: A colloidal dispersion of a metal chalcogenide material in divided state in an aqueous liquid phase selected from the group consisting of aqueous solutions and solutions including a mixture of water and at least one solvent that is miscible with water, wherein the carbon element of the material is present in a proportion of less than 2.5 wt. % as determined by elemental analysis, the concentration of the material in the colloidal dispersion is more than 40 g/l, and the colloidal dispersion has a charge potential value which is negative and the absolute value of which is higher than 20 mV.
    Type: Application
    Filed: March 7, 2012
    Publication date: February 13, 2014
    Applicants: UNIVERSITE PAUL SABATIER (TOULOUSE III ), ECOLE SUPERIEURE DES BEAUX-ARTS DE LA REUNION, INSTITUT NATIONAL DES SCIENCES APPLIQUEES DE TOULOUS, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE ( C.N.R.S.)
    Inventors: Jean-Yves Chane-Ching, Oana Zaberca, Azmach Tolesa, Andrea Balocchi
  • Publication number: 20130343980
    Abstract: A method for preparing a composition including synthetic mineral particles, in which: a hydrogel that is a precursor of the synthetic mineral particles is prepared, and the hydrogel is subjected to a hydrothermal treatment, characterized in that at least one step of the hydrothermal treatment is carried out with the addition of at least one carboxylate salt to the treatment medium, the carboxylate salt having the formula R—COOM?, where M? denotes a metal selected from the group consisting of Na and K, and R is selected from H and the alkyl groups that include fewer than 10 carbon atoms.
    Type: Application
    Filed: December 22, 2011
    Publication date: December 26, 2013
    Applicants: CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (C.N.R.S.), UNIVERSITE PAUL SABATIER TOULOUSE III
    Inventors: Christophe Le Roux, Francois Martin, Pierre Micoud, Angela Dumas
  • Patent number: 8574538
    Abstract: The invention relates to a solid material with the following formula (A): (Cu+1a-u; Ag+1u; Zn+2b-v-(y/2); Cd+2v; Sn+4c-w-(y/2); 1X+4w; 2X+3y; S?2x)(A), in which the solid material: is in divided state in the form of particles having a mean equivalent diameter of 15 nm to 400 nm; has, according to X-ray diffraction analysis of the solid material, a unique crystalline structure; is suitable for forming a stable dispersion of at least one solid material with formula (A) in a liquid, referred to as dispersion liquid, made up of at least one compound with a value of ?p higher than 8 and a value of ?H higher than 5.
    Type: Grant
    Filed: September 8, 2010
    Date of Patent: November 5, 2013
    Assignees: Universite Paul Sabatier Toulouse III, Centre National de la Recherche Scientifique (C.N.R.S.), Institut National des Sciences Appliquees de Toulouse, Ecole Superieure des Beaux-Arts de la Reunion
    Inventors: Jean-Yves Chane-Ching, Arnaud Gillorin, Xavier Marie, Pascal Dufour, Oana Zaberca
  • Publication number: 20130274210
    Abstract: The present invention relates to dendrimers with a monosaccharide, oligosaccharide or polysaccharide terminal group, to their preparation method and their therapeutic uses, notably anti-inflammatory uses.
    Type: Application
    Filed: August 31, 2011
    Publication date: October 17, 2013
    Applicant: UNIVERSITE PAUL SABATIER TOULOUSE III
    Inventors: Jacques Prandi, Germain Puzo, Cédric-Olivier Turrin, Emilyne Blattes, Alain Vercellone, Jérôme Nigou, Jean-Pierre Majoral, Anne-Marie Caminade
  • Publication number: 20130243719
    Abstract: The present invention relates to novel conjugates of active principles grafted to a polymer, to the nanoparticles comprising them, to their preparation and to their polymeric intermediates.
    Type: Application
    Filed: November 18, 2011
    Publication date: September 19, 2013
    Applicants: SANOFI, UNIVERSITE PAUL SABATIER TOULOUSE III, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (C.N.R.S.)
    Inventors: Abderrhamane Amgoune, Didier Bazile, Fethi Bensaid, Didier Bourissou, Eric Didier, Stephanie Greco, Harivardhan Reddy Lakkireddy, Serge Sable, Michel Veillard
  • Patent number: 8466095
    Abstract: The invention relates to a composite material including a metal matrix in which synthetic lamellar phyllosilicated mineral particles are distributed, characterized in that the lamellar phyllosilicated mineral particles are particles also called synthetic phyllosilicated nanoparticles (6) that are mineral, silico/germano-metal, lamellar, synthetic and hydrophilic, and have an average size of between 10 nm and 1 nm. The invention also relates to a substrate that comprises a lubricating coating consisting of such a material, and to an electrolytic deposition preparation method.
    Type: Grant
    Filed: December 18, 2008
    Date of Patent: June 18, 2013
    Assignees: Centre National de la Recherche Scientifique (C.N.R.S.), Luzenac Europe SAS, Universite Paul Sabatier Toulouse III
    Inventors: François Martin, Jean-Pierre Bonino, Pierre Micoud, Jocelyne Ferret, Cédric Lebre, Vincent Baylac
  • Publication number: 20130130052
    Abstract: The invention relates to a method for manufacturing a thermal barrier protection covering a superalloy metal substrate and comprising at least one metal sublayer (13) and a ceramic layer (14) based on zirconia stabilized with yttrium having a column structure defining pores. The following steps are applied: impregnation of a portion of the pores of the ceramic layer (14) with a sol based on zirconia is achieved via a sol-gel route and this in order to form an anchoring sublayer (22), on said ceramic layer topped with said anchoring sub-layer (22), a continuous protective layer (20) based on oxide, is formed via a sol-gel route, and a heat treatment is carried out, whereby an outer protection layer is formed against the attack of the thermal barrier (11) by CMASes. Application to the protection of aeronautical protection parts.
    Type: Application
    Filed: March 11, 2011
    Publication date: May 23, 2013
    Applicants: SNECMA, UNIVERSITE PAUL SABATIER-TOULOUSE III, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE
    Inventors: Justine Menuey, Florence Ansart, Jean-Pierre Bonino, Justine Fenech, Celine Viazzi