Patents Assigned to University of Saskatchewan
  • Patent number: 8734811
    Abstract: Compositions and methods for stimulating an immune response against Shiga toxin-producing Escherichia coli (STEC) antigens are disclosed. The compositions include a multiple epitope fusion protein comprising more than one epitope of an immunogenic STEC protein from more than one STEC serotype. Additional compositions include at least two purified STEC proteins, wherein the STEC proteins are selected from a full-length STEC protein, an immunogenic fragment or variant thereof, wherein at least one of the STEC proteins generates antibodies that react with STEC O157 and at least one other STEC serotype.
    Type: Grant
    Filed: April 6, 2010
    Date of Patent: May 27, 2014
    Assignee: University of Saskatchewan
    Inventors: Andrew Potter, David Asper, Dragan Rogan
  • Publication number: 20140113977
    Abstract: This disclosure relates to cyclodextrin-based drug delivery agents that comprise a cyclodextrin moiety covalently linked to a moiety of a gemini surfactant. Pharmaceutical compositions comprising the drug delivery agent and a therapeutic agent are also disclosed.
    Type: Application
    Filed: May 18, 2012
    Publication date: April 24, 2014
    Applicant: University of Saskatchewan
    Inventors: Ildiko Badea, Ronald Verrall, Peng Yang, Marianna Foldvari, Jackson Chitanda, Deborah Michel
  • Publication number: 20140065188
    Abstract: Compositions and methods for stimulating an immune response against a secreted enterohemorragic Escherichia coli (EHEC) antigen are disclosed. The compositions comprise EHEC cell culture supernatants.
    Type: Application
    Filed: November 12, 2013
    Publication date: March 6, 2014
    Applicants: University of Saskatchewan, The University of British Columbia
    Inventors: B. Brett Finlay, Andrew A. Potter
  • Patent number: 8598083
    Abstract: A novel strain of Trichoderma harzianum called TSTh20-1 is described. TSTh20-1 is useful in promoting plant growth, increasing water use efficiency of plants and in remediation of soil or water.
    Type: Grant
    Filed: September 16, 2010
    Date of Patent: December 3, 2013
    Assignees: University of Washington, University of Saskatchewan
    Inventors: Susan Gail Willets Kaminskyj, James Frederick Basinger, Xiaohui Bao, Russell John Rodriguez, Regina Soon Redman
  • Publication number: 20130316417
    Abstract: The present application includes a process and a microorganism of the genus Lactobacillus that converts glycerol to 1,3-propanediol. The conversion is accomplished by a proprietary microorganism that is easily cultured in glycerol rich waste products of ethanol production, such as thin stillage.
    Type: Application
    Filed: October 7, 2011
    Publication date: November 28, 2013
    Applicant: University of Saskatchewan
    Inventors: Martin J.T. Reaney, Monique Haakensen, Darren Korber, Takuji Tanaka, Kornsulee Ratanapariyanuch
  • Patent number: 8586057
    Abstract: Compositions and methods for stimulating an immune response against a secreted enterohemorragic Escherichia coli (EHEC) antigen are disclosed. The compositions comprise EHEC cell culture supernatants.
    Type: Grant
    Filed: October 22, 2007
    Date of Patent: November 19, 2013
    Assignees: The University of British Columbia, University of Saskatchewan
    Inventors: B. Brett Finlay, Andrew A. Potter
  • Publication number: 20130305419
    Abstract: A Coleus plant particularly distinguished by triangular leaves with many deep lobes and yellow-green leaves with purple margins, is disclosed.
    Type: Application
    Filed: May 10, 2012
    Publication date: November 14, 2013
    Applicant: University of Saskatchewan
    Inventor: Robert H. Bors
  • Publication number: 20130305420
    Abstract: A Coleus plant particularly distinguished by unique elongated, bronze and orange-colored secondary leaflets resembling a lobster claw and attached to the main leaf by single narrow veins, is disclosed.
    Type: Application
    Filed: May 10, 2012
    Publication date: November 14, 2013
    Applicant: University of Saskatchewan
    Inventor: Robert H. Bors
  • Patent number: 8546087
    Abstract: The present invention relates to compounds, compositions, methods and/or kits for determining and/or predicting and/or diagnosing and/or treating restenosis in a patient.
    Type: Grant
    Filed: June 2, 2010
    Date of Patent: October 1, 2013
    Assignee: University of Saskatchewan
    Inventor: Kailash Prasad
  • Patent number: 8524249
    Abstract: A composition comprising an isolated fowl adenovirus (FAdV), wherein the FAdV is a strain selected from FAdV-2, FAdV-7, FAdv-8a, FAdV-8b, FAdV-8a/8b or FAdV-11 serotype strains; and a suitable carrier and methods for inducing protective immunity in a subject and/or its progeny.
    Type: Grant
    Filed: December 15, 2010
    Date of Patent: September 3, 2013
    Assignees: University of Saskatchewan, University of Guelph
    Inventors: Susantha Gomis, Suresh Kumar Tikoo, Davor Ojkic
  • Patent number: 8518128
    Abstract: The present disclosure relates to fuel additive compositions comprising one or more hydrogen bonding compounds derived from a long chain fatty acid, and one or more esters of a second long chain fatty acid. Such fuel additives improve the lubricity of the fuel.
    Type: Grant
    Filed: November 3, 2008
    Date of Patent: August 27, 2013
    Assignee: University of Saskatchewan
    Inventors: Martin Reaney, Sunmin Wang, Yunhua Jia
  • Patent number: 8501401
    Abstract: An isolated steroidogenesis modified cell comprising one or more steroid biosynthesis knock down nucleic acid operatively linked to a promoter, wherein the steroid biosynthesis knock down nucleic acid reduces the expression of a gene selected from the group CYP21A2, CYP11A1, CYP17A1, CYP19A1, 3-?HSD1, 3-?HSD2, 17-?HSD1, StAR, HMGR, CYP11B2, CYP11B1, 5?-Reductase 2, SULT1E1, CYP3A4 and UTG1A1, wherein the cell comprises reduced expression of one or more of said genes. The cells are useful for identifying endocrine disruptors. Accordingly, the disclosure includes in a further aspect a screening assay for identifying an endocrine disruptor comprising: a) contacting a cell described herein with a test substance; b) determining a level of at least one steroid or steroidogenic gene mRNA or enzyme activity; wherein a modulation in the level of the at least one steroid or steroidogenic gene mRNA or enzyme activity compared to a control is indicative that the test substance is an endocrine disruptor.
    Type: Grant
    Filed: September 14, 2012
    Date of Patent: August 6, 2013
    Assignee: University of Saskatchewan
    Inventors: Xiaowei Zhang, Markus Hecker, John P. Giesy
  • Patent number: 8451028
    Abstract: Methods and devices for detecting single-event transients in combinational logic circuits and other circuits. A sensing circuit detects a voltage or current deviation at a bulk contact node of a transistor. Output of the sensing circuit is amplified and used to flip a latch. Output of the latch may be evaluated and used in possible error correction measures.
    Type: Grant
    Filed: March 22, 2011
    Date of Patent: May 28, 2013
    Assignee: University of Saskatchewan
    Inventors: Li Chen, Zhichao Zhang, Tao Wang
  • Patent number: 8440802
    Abstract: The present invention provides for selection of bovine animals that will display phenotypes associated with increased rates of growth. These phenotypes include hot carcass weight, average daily gain, shipping weight, end of test rib eye area, and adjusted weaning weight which is a measure of post-natal growth, based on the knowledge of their CRH, POMC and MC4R genotypes. The predictive value comes from the discovery that certain single nucleotide polymorphisms (SNPs) in these genes are linked to higher growth rate phenotypes. Specifically, the phenotypes that correlated with specific SNP's are end-of-test rib-eye area, adjusted weaning weight, average daily gain, shipping weight and hot carcass weight. The invention also provides novel kits that can be used in making the determination of these genotypes.
    Type: Grant
    Filed: July 12, 2011
    Date of Patent: May 14, 2013
    Assignee: University of Saskatchewan
    Inventors: Fiona Buchanan, Tracy D. Thue, Dianne Winkelman-Sim
  • Publication number: 20130116177
    Abstract: Described herein are methods for synchronizing ovulation in a herd, inducing superovulation in a single animal, and improving frequency of successful implantation and development of fertilized ova.
    Type: Application
    Filed: May 19, 2011
    Publication date: May 9, 2013
    Applicant: University of Saskatchewan
    Inventors: Roger Pierson, Gregg Adams
  • Patent number: 8410010
    Abstract: The present disclosure relates to a process for the production of a base complex catalyst comprising reacting a hydroxide base with a polyalcohol, under vacuum pressure, at a temperature in the range of about 60° C. to about 220° C., wherein the mole ratio of the hydroxide base to the polyalcohol is greater than about 2:1.
    Type: Grant
    Filed: December 1, 2008
    Date of Patent: April 2, 2013
    Assignee: University of Saskatchewan
    Inventors: Martin J. T. Reaney, Jianheng Shen, Douglas W. Soveran
  • Patent number: 8404884
    Abstract: A process for the extraction of macromolecules from a biomass material comprising: a) contacting the biomass material with a solution comprising thin stillage to provide a slurry comprising undissolved solids, dissolved solids and suspended solids; and b) separating undissolved solids from the slurry to provide a solid fraction and a liquid fraction; and wherein the macromolecules are comprised in the dissolved solids.
    Type: Grant
    Filed: March 28, 2011
    Date of Patent: March 26, 2013
    Assignee: University of Saskatchewan
    Inventors: Martin J. Reaney, Kornsulee Ratanapariyanuch
  • Patent number: 8383172
    Abstract: Methods for separation and recovery of individual cyclic peptides from plant materials, said method comprising the steps of: (a) extracting an oil from a plant material; (b) separating the extracted oil into a non-polar fraction and a polar fraction; (c) separation and recovery of cyclic peptides from the non-polar fraction, and (d) separation and recovery of cyclic peptides from the polar fraction. The methods are suitable for separation and recovery of individual cyclolinopeptides from flax seed oil. Individual cyclolinopeptides are useful for modulation physiological disorders associated with apoptosis. Modified flaxseed oils may be produced by commingling flaxseed oils absent cyclolinopeptides, with at least one cyclolinopeptide separated and recovered with the methods disclosed herein.
    Type: Grant
    Filed: December 22, 2008
    Date of Patent: February 26, 2013
    Assignee: University of Saskatchewan
    Inventors: Martin J. Reaney, Yunhua Jia, Jianheng Shen, Cynthia Schock, Nancy Tyler, Jim Elder, Sarabjeet Singh
  • Patent number: 8299238
    Abstract: An isolated steroidogenesis modified cell comprising one or more steroid biosynthesis knock down nucleic acid operatively linked to a promoter, wherein the steroid biosynthesis knock down nucleic acid reduces the expression of a gene selected from the group CYP21A2, CYP11A1, CYP17A1, CYP19A1, 3-?HSD1, 3-?HSD2, 17-?HSD1, StAR, HMGR, CYP11B2, CYP11B1, 5?-Reductase 2, SULT1E1, CYP3A4 and UTG1A1, wherein the cell comprises reduced expression of one or more of said genes. The cells are useful for identifying endocrine disruptors. Accordingly, the disclosure includes in a further aspect a screening assay for identifying an endocrine disruptor comprising: a) contacting a cell described herein with a test substance; b) determining a level of at least one steroid or steroidogenic gene mRNA or enzyme activity; wherein a modulation in the level of the at least one steroid or steroidogenic gene mRNA or enzyme activity compared to a control is indicative that the test substance is an endocrine disruptor.
    Type: Grant
    Filed: September 16, 2010
    Date of Patent: October 30, 2012
    Assignee: University of Saskatchewan
    Inventors: Xiaowei Zhang, Markus Hecker, John P. Giesy
  • Patent number: PP24309
    Abstract: A Coleus plant particularly distinguished by unique elongated, bronze and orange-colored secondary leaflets resembling a lobster claw and attached to the main leaf by single narrow veins, is disclosed.
    Type: Grant
    Filed: May 10, 2012
    Date of Patent: March 11, 2014
    Assignee: University of Saskatchewan
    Inventor: Robert H. Bors