Patents Assigned to University of South Florida
  • Patent number: 10688080
    Abstract: The present disclosure provides compositions including a beta-lactamase inhibitor, pharmaceutical compositions including a beta-lactamase inhibitor, methods of treatment of a condition (e.g., infection) or disease, methods of treatment using compositions or pharmaceutical compositions, and the like.
    Type: Grant
    Filed: July 30, 2018
    Date of Patent: June 23, 2020
    Assignees: UNIVERSITY OF SOUTH FLORIDA, The Regents of the University of California
    Inventors: Yu Chen, Nicholas Joseph Torelli, Orville Antonio Pemberton, Xiujun Zhang, Adam Renslo, Kyle Defrees, Priyadarshini Jaishankar
  • Patent number: 10690121
    Abstract: In one embodiment, a thermodynamic system includes multiple types of thermodynamic cycles and multiple types of solar thermal fields that provide thermal energy to the thermodynamic cycles.
    Type: Grant
    Filed: October 31, 2012
    Date of Patent: June 23, 2020
    Assignee: University of South Florida
    Inventors: Dharendra Yogi Goswami, Elias K. Stefanakos, Nitin Goel
  • Patent number: 10688063
    Abstract: Provided herein are methods of preventing or reducing weight gain in a subject in need thereof by administering 2-acetylcyclopentane-1,3-dione (ACPD).
    Type: Grant
    Filed: October 11, 2017
    Date of Patent: June 23, 2020
    Assignees: University of South Florida, The United States Government as Represented by the Department of Veterans Affairs of General Counsel- PSG IV (024)
    Inventors: Robert Vito Farese, Mini Paliyath Sajan
  • Patent number: 10691836
    Abstract: Methods and systems are provided for a charge withholding converter reshuffling technique that decorrelates input power of a multi-phase switched capacitor (SC) voltage converter relative to the output power provided to a load. The load may be a cryptographic device. The technique provides a countermeasure against power analysis attacks. A controller including a first random number generator coupled to the stages of the SC voltage converter controls gating for charging a first subset of the stages. A controller including a second random number generator coupled the stages of the SC voltage converter controls gating for discharging a second subset the stages. A number of the switched capacitor stages maintain their charge beyond the switch period in which they are charged. The SC voltage converter withholds a random portion of input charge and delivers this charge to the load after a random time period.
    Type: Grant
    Filed: April 30, 2018
    Date of Patent: June 23, 2020
    Assignee: University of South Florida
    Inventors: Selcuk Kose, Weize Yu
  • Patent number: 10687876
    Abstract: A method and system for performing bone fusion and/or securing one or more bones, such as adjacent vertebra, are disclosed. The screws include a threaded tip connected to a main shaft and a threaded outer sleeve that rotates relative to the outer shaft until locked down. Independent rotation of the threaded outer sleeve relative to the threaded distal tip allows compression or distraction to modify the gap between the vertebral bodies. The screws are passed from the inferior to superior vertebra or superior to inferior, for example, through a trans-pedicular route to avoid neurological compromise. At the same time, the path of screw insertion is oriented to reach superior or inferior vertebra. An intervertebral cage of the system is configured for lateral expansion from a nearly straight configuration to form a large footprint in the disc space. The screws and cage may be combined for improved fixation with minimal invasiveness.
    Type: Grant
    Filed: May 3, 2018
    Date of Patent: June 23, 2020
    Assignees: H. Lee Moffitt Cancer Center and Research Institute, Inc., University of South Florida
    Inventors: Frank D. Vrionis, Kamran Aghayev, Sabrina A Gonzalez Blohm, James J. Doulgeris
  • Publication number: 20200192174
    Abstract: In one embodiment, an electrochromic device includes a single active layer configured to be alternately placed in a light-transmitting state in which relatively large amounts of light can be transmitted through the active layer and a light-blocking state in which relatively small amounts of light can be transmitted through the active layer, wherein the device comprises no other layers of material that contribute to transitioning between the two states.
    Type: Application
    Filed: May 16, 2018
    Publication date: June 18, 2020
    Applicant: University of South Florida
    Inventors: Manoj Kumar Ram, Elias K. Stefanakos
  • Publication number: 20200181784
    Abstract: Photoelectrochemical cells including a cathode including alpha-hematite and a metal dichalcogenide, an anode including a conducting polymer, and an electrolyte.
    Type: Application
    Filed: February 18, 2020
    Publication date: June 11, 2020
    Applicant: University of South Florida
    Inventors: Hussein Alrobei, Manoj Kumar Ram
  • Patent number: 10680797
    Abstract: Methods and systems are provided for a security adaptive (SA) voltage converter that receives input power from a power source and provides power to a cryptographic system. The SA voltage converter triggers countermeasures against leakage power analysis (LPA) attacks that slow down an operating frequency of the cryptographic circuit. When an LPA attack is detected, a discharging resistor sinks redundant current to alter the signature of load power dissipation of at the input to the SA voltage converter system. The SA voltage converter includes a converter reshuffling converter. The power dissipation induced by the discharging resistor, as measured at the input received from the power source, is scrambled by the SA voltage converter to increase noise inserted into the input power and to alter the power profile that is measured for the cryptographic circuit.
    Type: Grant
    Filed: April 30, 2018
    Date of Patent: June 9, 2020
    Assignee: University of South Florida
    Inventors: Selcuk Kose, Weize Yu
  • Patent number: 10677914
    Abstract: In one embodiment, a method for detecting buried objects includes receiving ground penetrating radar (GPR) signals captured at discrete locations along a surface of a medium in which an object may be buried, computing parameters based on the received GPR signals that are indicative of the proximity of a buried object, plotting the computed parameters as a function of location, determining an apex of a hyperbola that results from the plotting of the computed parameters, and designating a location at which the apex occurs as an estimated location of the buried object.
    Type: Grant
    Filed: December 5, 2018
    Date of Patent: June 9, 2020
    Assignees: University of South Florida, University of the Sciences in Philadelphia
    Inventors: Chris P. Tsokos, Abolfazl Saghafi, Sajad Jazayeri, Sanaz Esmaeili
  • Patent number: 10675301
    Abstract: A broad-based remediation mechanism against MRFs and alternative fecal indicators such as multidrug resistant Pseudomonas aeruginosa, including nanotechnology formulations and methodologies that may be used to develop novel mitigation strategies against certain drug resistant bacterial strains. The current invention relates to mitigation of drug resistant bacteria, for example in hospitals and in food animals, and to the identification. The invention uses hybrid nanomaterials comprising oligo-chitosan and zinc oxide formulated as nanoparticles and micelles. The invention also relates to the treatment of multi-drug resistant biofilms which mimic in vivo conditions. The inventors unexpectedly found unique properties of very small oligomers of chitosan that effectively mitigate MRF and alternative resistant strain-induced illnesses without compromising the balance of the beneficial flora in the physiological and ecological microenvironments.
    Type: Grant
    Filed: January 14, 2019
    Date of Patent: June 9, 2020
    Assignee: University of South Florida
    Inventors: Shyam S. Mohapatra, Alya Limayem
  • Patent number: 10678907
    Abstract: A runtime attack can be detected on a big data system while processes are executed on various computing devices. A behavior profile can be maintained for tasks or processes running on different computing devices. The existence of a call variance in one of the traces for one of the behavior profiles can be determined. A memory variance can also be detected in one of the behavior profiles. A runtime attack has occurred when both the memory variance and the call variance are determined to exist.
    Type: Grant
    Filed: January 26, 2018
    Date of Patent: June 9, 2020
    Assignee: University of South Florida
    Inventors: Santosh K. Aditham, Nagarajan Ranganathan
  • Patent number: 10675283
    Abstract: Disclosed herein are compositions and methods for transitioning or converting a white adipocyte to a beige adipocyte. The compositions and methods may be used in the treatment of obesity. In some embodiments, the compositions include a compound selected from DC677 and DC761.
    Type: Grant
    Filed: March 26, 2018
    Date of Patent: June 9, 2020
    Assignees: University of South Florida, The United States Government as Represented by the Department Of Veterans Affairs
    Inventors: Denise Ratzlaff Cooper, Ryan Adam Kirchoffer, Robert Pleasants Sparks, Wayne Charles Guida
  • Publication number: 20200172784
    Abstract: In one embodiment, a metal-plated polymer object includes a polymer surface, a first metal layer that has been applied to the polymer surface to render it electrically conductive, and a second metal layer that has been deposited on the first metal layer.
    Type: Application
    Filed: December 10, 2019
    Publication date: June 4, 2020
    Applicant: University of South Florida
    Inventors: Jaspreet Dhau, D. Yogi Goswami, Chand K. Jotshi, Elias K. Stefanakos
  • Publication number: 20200174126
    Abstract: A system and method of adjusting a field of view in an imaging system includes transmitting light across a transmission optical path and defining a field of view encompassing both uniform and spatially tenuous target objects within the transmitted light. A sensor within a return optical path of reflected light from at least a portion of one of the target objects allows a data processing computer to compile an image from a series of data outputs from the sensor. The image is analyzed to determine a region of interest within the image and by dynamically adjusting the light source, the computer is configured to change the field of view of the light source such that the image includes a higher resolution and/or signal intensity for the region of interest. The region of interest may include at least one spatially tenuous target object.
    Type: Application
    Filed: November 22, 2019
    Publication date: June 4, 2020
    Applicant: University of South Florida
    Inventor: Dennis Karl Killinger
  • Patent number: 10667701
    Abstract: In one embodiment, a system for determining physiological parameters from blood flow dynamics includes a catheter configured for insertion into a blood vessel of a subject through which blood flows, a flexible barrier associated with the catheter configured to oscillate in response to changes in pressure of the blood within the catheter, and a pressure field microphone configured to measure a pressure field induced by the oscillation of the flexible barrier and to generate a measured acoustic pressure signal that can be processed to determine the physiological parameters.
    Type: Grant
    Filed: February 5, 2018
    Date of Patent: June 2, 2020
    Assignee: University of South Florida
    Inventors: Prashanth Chetlur Adithya, Ravi Sankar, Wilfrido Alejandro Moreno, Stuart Hart
  • Patent number: 10668027
    Abstract: Described herein are methods of treating an Acanthamoeba infection in a subject in need thereof by administering an amount of allopurinol.
    Type: Grant
    Filed: August 20, 2018
    Date of Patent: June 2, 2020
    Assignee: UNIVERSITY OF SOUTH FLORIDA
    Inventors: Andreas Seyfang, Timothy J. Locksmith, Adarsh Bellur, Deandre Wells, Matthew Doenges
  • Patent number: 10669241
    Abstract: Described herein are compounds and formulations thereof that can bind PTEN. Also described herein are methods of using the compounds and formulations thereof that can bind PTEN. In some embodiments, the method can include administering an amount of a compound or formulation described herein to a subject in need thereof.
    Type: Grant
    Filed: February 1, 2019
    Date of Patent: June 2, 2020
    Assignee: UNIVERSITY OF SOUTH FLORIDA
    Inventors: Vrushank G. Davé, Jianfeng Cai
  • Patent number: 10673625
    Abstract: Disclosed are various embodiments for certificate-free cryptosystems that achieve significant computational and communication efficiency as compared to prior systems. A private key generator (PKG) generates a master public key and a master private key unique to the PKG; receives identifying information for at least one client device; generates a public key for the at least one client device; generates a private key for the at least one client device by: performing a hash of the identifying information using the public key generated for the at least one client device to generate a plurality of indices; identifying values corresponding to the indices from the master private key; and deriving the private key based at least in part on a summation of the values corresponding to the indices; and sends the public key and the private key to the at least one client device.
    Type: Grant
    Filed: June 15, 2019
    Date of Patent: June 2, 2020
    Assignee: University of South Florida
    Inventors: Rouzbeh Behnia, Muslum Ozgur Ozmen, Attila Altay Yavuz
  • Patent number: 10660873
    Abstract: Methods of treating or preventing allergic or pulmonary diseases characterized by endothelial dysfunction with Alda-1 are presented. Treatment of pulmonary endothelial cells subjected to hyperoxia with Alda-1 showed an increase in ALDH2 activity and expression. Treatment with Alda-1 also illustrated a decrease in oxidative stress, a decrease in reactive oxygen species (ROS), a decrease in apoptosis, a decrease in inflammation and an enhancement of mitochondrial membrane potential.
    Type: Grant
    Filed: February 22, 2019
    Date of Patent: May 26, 2020
    Assignee: University of South Florida
    Inventors: Narasaiah Kolliputi, Richard F. Lockey, Lakshmi Galam
  • Patent number: 10660315
    Abstract: A catalytic reactor using catalyst-coated optical fiber technology that will allow the control of light and its emission mode to quantitatively optimize catalytic degradation of off-flavor compounds. This degradation can be greatly enhanced by increasing the surface area of the catalyst. Coating individual transparent optical fibers and aligning them in a canister configuration allows the treatment of large volumes of water in portable and scalable reactors.
    Type: Grant
    Filed: November 20, 2017
    Date of Patent: May 26, 2020
    Assignee: University of South Florida
    Inventors: Norma A. Alcantar, Daniela Miranda de Lima Stebbins, Kevan Main