Patents Assigned to University of South Florida
  • Patent number: 11828726
    Abstract: Disclose herein is a portable platform based on a direct digital synthesizer (DDS) is investigated for the orthogonal SAW sensor, integrating signal synthesis, gain control, phase/amplitude measurement, and data processing in a small, portable electronic system. The disclosed platform allows for simultaneous removal of non-specific binding proteins, and mixing, as well as improved incubation time.
    Type: Grant
    Filed: November 14, 2022
    Date of Patent: November 28, 2023
    Assignee: UNIVERSITY OF SOUTH FLORIDA
    Inventors: Venkat R. Bhethanabotla, Shuangming Li
  • Patent number: 11815779
    Abstract: In one embodiment, an electrochromic device includes a single active layer configured to be alternately placed in a light-transmitting state in which relatively large amounts of light can be transmitted through the active layer and a light-blocking state in which relatively small amounts of light can be transmitted through the active layer, wherein the device comprises no other layers of material that contribute to transitioning between the two states.
    Type: Grant
    Filed: June 13, 2022
    Date of Patent: November 14, 2023
    Assignee: UNIVERSITY OF SOUTH FLORIDA
    Inventors: Manoj Kumar Ram, Elias K. Stefanakos
  • Patent number: 11814385
    Abstract: Disclosed herein are compounds that can prevent and treat C. difficile by inhibiting sporulation. Also disclosed herein are compositions and formulations comprising the compound disclosed herein. Methods of preventing and treating C. difficile comprising administering the compounds described herein are also disclosed.
    Type: Grant
    Filed: June 27, 2022
    Date of Patent: November 14, 2023
    Assignee: University of South Florida
    Inventors: Yu Chen, Michael Sacco, James Leahy, Elena Bray, Xingmin Sun, Xiujun Zhang
  • Patent number: 11809475
    Abstract: In accordance with some embodiments, systems, methods, and media for processing and representing multivariate sensor information gathered from multiple sources are provided. In some embodiments, the method comprises: receiving a data sequences from respective sources; identifying a shortest data sequence that corresponds to a first interval; calculating, for pairs of data sequences, a similarity value over the first interval; forming a first segment of a representative data sequence that is a weighted combination of the data sequences over the first interval based on similarity values associated with the data sequences; truncating at least a subset of data sequences to exclude elements corresponding to the first interval; identifying a shortest data sequence corresponding to a second interval; forming a second segment of the representative data sequence based on similarity values associated with the data sequences; and concatenating the first segment and the second segment of the representative data sequence.
    Type: Grant
    Filed: December 14, 2021
    Date of Patent: November 7, 2023
    Assignee: UNIVERSITY OF SOUTH FLORIDA
    Inventors: Ismail Uysal, Alla Abdella
  • Patent number: 11806328
    Abstract: Ketone supplementation, such as through use of precursors of beta-hydroxybutyrate (BHB) and acetoacetate (AcAc), increased blood levels of ketone bodies, increases blood flow and wound closure in ischemic young and aged fisher rats significantly earlier compared to standard diet in aged rats. In vitro experiments with ketone bodies demonstrate decreased mitochondrial and cytosolic ROS in young and aged primary human dermal fibroblasts (PHDF). Ketone bodies increased migration in young and aged PHDFs.
    Type: Grant
    Filed: December 15, 2020
    Date of Patent: November 7, 2023
    Assignee: UNIVERSITY OF SOUTH FLORIDA
    Inventors: Dominic Paul D'Agostino, Shannon Kesl
  • Patent number: 11806312
    Abstract: A medication adherence system and corresponding medication box for improving medication adherence. The system includes the medication box, which is transparent and has a machine-readable marker, such as a QR code, on or beneath the floor thereof. The marker is capable of being scanned and read through the transparent bottoms of individual chambers. Data embedded in the marker includes, but is not limited to, the user's medication plan, the date and time when the medication is to be ingested, and instructions for recording the date and time when the marker is scanned and read. The underlying software program/application processes this information and provides an indication as to the user's compliance with the medication plan.
    Type: Grant
    Filed: February 14, 2022
    Date of Patent: November 7, 2023
    Assignees: UNIVERSITY OF SOUTH FLORIDA, THE UNITED STATES GOVERNMENT AS REPRESENTED BY THE DEPARTMENT OF VETERANS AFFAIRS
    Inventors: William Diehl Kearns, Kimberly Ann Crosland, Jeffrey D. Craighead, James Leonard Fozard
  • Patent number: 11806356
    Abstract: Disclosed are compositions and methods for delaying or preventing idiopathic preterm birth.
    Type: Grant
    Filed: September 20, 2021
    Date of Patent: November 7, 2023
    Assignee: University of South Florida
    Inventors: Charles Lockwood, Ozlem Guzeloglu-Kayisli, Umit Ali Kayisli, Frederick Schatz
  • Patent number: 11809597
    Abstract: A public key generated by each user of a plurality of users is used to encrypt the contacts for that user. The results are sent to a server by each user. The key generated by each user is then distributed to every other user in the system, and each recipient encrypts their contacts with the keys. The result of these encryptions for all contacts for all recipients is then received by the server, and the server computes an encrypted computation of equality of two contacts and sends all computations back to the original user. The user can use the homomorphic property of the crypto protocol (e.g., a private key) to determine a set of users that are matched as contacts with the other users. The binary results are returned to the server, and the server computes a graph using the results.
    Type: Grant
    Filed: March 26, 2021
    Date of Patent: November 7, 2023
    Assignee: University of South Florida
    Inventors: Jean-Francois Biasse, William Youmans, Sriram Chellappan, Nathan Fisk, Noyem Khan
  • Patent number: 11809563
    Abstract: A system and method of protecting against control-flow attacks provides two complementary, transparent, and strong security policies for the RTL design at a hardware level. The approach performs static analysis of controller, followed by lightweight instrumentation, such that CFI is enforced in-place and at runtime. The modified controller follows conservative CFG with the help of a monitor.
    Type: Grant
    Filed: July 7, 2021
    Date of Patent: November 7, 2023
    Assignee: University of South Florida
    Inventors: Srinivas Katkoori, Sheikh Ariful Islam
  • Patent number: 11808710
    Abstract: Disclosed herein are methods for measuring the ionic strengths of the natural water sources. Also disclosed herein are systems used to measure an ionic strength of the natural water sources. More specifically disclosed herein are methods and systems utilizing spectroscopic pH measurements and calculations of the ionic strength as a function of the measured pH.
    Type: Grant
    Filed: June 24, 2021
    Date of Patent: November 7, 2023
    Assignee: University of South Florida
    Inventor: Robert H. Byrne
  • Patent number: 11808290
    Abstract: A fluid flow conditioning apparatus having self-adjusting tab members that reduce flow losses within a conduit. A plurality of tabular members is affixed to an insertion plate-type flow conditioner. Tabular members are cojoined in pairs at their leading edges. When the cojoined pair of the first tabular member and the second tabular member are placed into a fluid flow, an angle between the first tabular member and the second tabular member is configured to decrease in response to static and dynamic pressure exerted onto the outer surfaces of the tabular members by the fluid flow. The tabular members may be made of a hyperplastic material configured to undergo an elastic deformation and exhibit flapping due to the dynamic pressure of the fluid flow. Tabular members maybe cojoined by a hinge configured to partially close in response to pressure exerted by the fluid flow, decreasing the angle between the tabular members.
    Type: Grant
    Filed: December 20, 2021
    Date of Patent: November 7, 2023
    Assignee: University of South Florida
    Inventors: Rajat Mittal, Dharendra Yogi Goswami
  • Patent number: 11810475
    Abstract: Education curricula materials include encoded indicia such as a QR code that contains information related to identifying requested augmented reality image data from a server over a network. By scanning the QR code, a computer uses its decoding software to create a data set for transmitting to the server. The data set may include an identifier for selected augmented reality image data associated with the user's curriculum, information about the curriculum at issue, the academic level of the user, and any other data necessary to ensure that the most appropriate augmented reality image data is transmitted back to the computer. The server transmits comprehensive augmented reality image data back to the computer for viewing on a computerized display accessible by a student. Part of the content may include an interactive pedagogical agent that helps the student with a part of the instruction related to a portion of the curriculum.
    Type: Grant
    Filed: December 12, 2022
    Date of Patent: November 7, 2023
    Assignee: UNIVERSITY OF SOUTH FLORIDA
    Inventors: Sara Ashley Smith, Maria Soledad Carlo, Sanghoon Park, Howard Kaplan
  • Patent number: 11803968
    Abstract: Systems and methods for automated stereology are provided. A method can include providing an imager for capturing a Z-stack of images of a three-dimensional (3D) object; constructing extended depth of field (EDF) images from the Z-stack of images; performing a segmentation method on the EDF images including estimating a Gaussian Mixture Model (GMM), performing morphological operations, performing watershed segmentation, constructing Voronoi diagrams and performing boundary smoothing; and determining one or more stereology parameters such as number of cells in a region.
    Type: Grant
    Filed: May 5, 2021
    Date of Patent: October 31, 2023
    Assignees: UNIVERSITY OF SOUTH FLORIDA, STEREOLOGY RESOURCE CENTER, INC.
    Inventors: Peter Randolph Mouton, Hady Ahmady Phoulady, Dmitry Goldgof, Lawrence O. Hall
  • Patent number: 11802267
    Abstract: Described herein are compositions and methods to cryopreserve sporozoites. In some aspects, the method can include the step of placing harvested salivary glands containing sporozoites into an insect-based medium.
    Type: Grant
    Filed: May 17, 2022
    Date of Patent: October 31, 2023
    Assignee: UNIVERSITY OF SOUTH FLORIDA
    Inventors: John H. Adams, Alison Elizabeth Roth
  • Patent number: 11800988
    Abstract: In one embodiment, a system for monitoring heart rate variability including an electrode configured to be placed against a user’s chest and generate heart beat data and a data collection and processing device that receives the heart beat data from the electrode, the data collection and processing device being configured to execute a heart rate variability program configured to continually determine the user’s heart rate variability in real time based upon the heart beat data and to determine whether or not the user is in physiological distress based upon the determined heart rate variability.
    Type: Grant
    Filed: March 8, 2018
    Date of Patent: October 31, 2023
    Assignee: University of South Florida
    Inventor: Joseph Dituri
  • Patent number: 11801312
    Abstract: A method of treating cancerous tumors is presented herein. The method includes injecting an effective dose of a plasmid encoded for IL-12, B7-1 or IL-15 into a cancerous tumor and subsequently administering at least one high voltage, short duration pulse to the tumor. The electroporation pulses may be administered at least 700V/cm for a duration of less than 1 millisecond. The intratumor treatments with electroporation may be administered in at least a two-treatment protocol with the time between treatments being about 7 days. The intratumor treatments with electroporation may be administered in a three-treatment protocol with a time of four days between the first and second treatments and a time of three days between the second and third treatments. It was found that the intratumor treatments using electroporation not only resulted in tumor regression but also induced an immune memory response which prevented the formation of new tumors.
    Type: Grant
    Filed: October 5, 2020
    Date of Patent: October 31, 2023
    Assignee: University of South Florida
    Inventors: Richard Heller, Melinda Lee Lucas
  • Patent number: 11794166
    Abstract: Perovskite oxides and catalysts containing the perovskite oxides are provided for the thermochemical conversion of carbon dioxide to carbon monoxide. The perovskite oxides can exhibit large carbon monoxide production rates and/or low carbon monoxide production onset temperatures as compared to existing materials. Reactors are provided containing the perovskite oxides and catalysts, as well as methods of use thereof for the thermochemical conversion of carbon dioxide to carbon monoxide.
    Type: Grant
    Filed: February 26, 2021
    Date of Patent: October 24, 2023
    Assignee: UNIVERSITY OF SOUTH FLORIDA
    Inventors: John N. Kuhn, Debtanu Maiti, Yolanda A. Daza, Bryan J. Hare, Adela E. Ramos, Venkat R. Bhethanabotla
  • Patent number: 11793177
    Abstract: The present invention concerns non-human animals with cells having a genome that is lacking the entire E3 ubiquitin ligase (Ube3a) gene (including all isoforms and alternative promoters). These animals are useful for modeling Angelman Syndrome. The invention also includes methods for assessing the effect of an agent, such as potential therapeutics, on an animal model by exposing the animal or cells, tissues, or organs isolated therefrom, to an agent of interest.
    Type: Grant
    Filed: October 3, 2017
    Date of Patent: October 24, 2023
    Assignees: UNIVERSITY OF SOUTH FLORIDA, THE REGENTS OF THE UNIVERSITY OF CALIFORNIA, THE TEXAS A&M UNIVERSITY SYSTEM
    Inventors: Edwin John Weeber, David J. Segal, Henriette O'Geen, Benjamin Pyles, Scott V. Dindot
  • Patent number: 11787845
    Abstract: Provided herein are synthetic P. vivax antigens, antibodies and pharmaceutical formulations and vaccines thereof. Also provided herein are methods of treating and/or preventing Plasmodium infection and/or disease by administering the synthetic P. vivax antigens, antibodies and pharmaceutical formulations and vaccines thereof.
    Type: Grant
    Filed: November 24, 2020
    Date of Patent: October 17, 2023
    Assignees: UNIVERSITY OF SOUTH FLORIDA, WASHINGTON UNIVERSITY, CASE WESTERN RESERVE UNIVERSITY
    Inventors: John H. Adams, Christopher L. King, Niraj H. Tolia, Edwin Chen, Nichole Diane Salinas, Miriam Thankam George, Francis B. Ntumngia, Samantha Jones Barnes
  • Patent number: 11788155
    Abstract: Disclosed herein is a method to isolate and cultivate the lung microbiome obtained from bronchoalveolar lavage. The disclosed method involves lung microbiome culturomics based on three different media for both aerobic and fastidious anaerobic bacteria. The disclosed method allows for amplification of the lung microbiome, which can be used, for example, for subsequent testing of antibiotic sensitivity, drug resistance, or for lung microbiome transplantation.
    Type: Grant
    Filed: June 5, 2020
    Date of Patent: October 17, 2023
    Assignee: UNIVERSITY OF SOUTH FLORIDA
    Inventors: Andreas Seyfang, Nirmal S. Sharma