Abstract: Methods for producing lactams from oximes by performing a Beckmann rearrangement using a silicoaluminophosphate catalyst are provided. These catalysts may be used in gas phase or liquid phase reactions to convert oximes into lactams. High conversion of oxime and high selectivity for the desired lactams are produced using the disclosed methods, including high conversion and selectivity for ?-caprolactam produced from cyclohexanone oxime and high conversion and selectivity for ?-laurolactam produced from cyclododecanone oxime.
Type:
Application
Filed:
May 9, 2014
Publication date:
May 7, 2015
Applicants:
Honeywell International Inc., University of Southampton
Inventors:
Alan B. Levy, Robert Raja, Matthew E. Potter
Abstract: An absorption cell for microfluidic chemical analysis made from tinted or colored polymers, for example polymethylmethacrylate (PMMA), in which microfluidic channels are cut. Light is coupled into the absorption cell via two windows (typically 200 um thick) that are retained at either end of the channel. Absorption is measured using a light source, such as a light emitting diode (LED) and a photodiode butted against the windows. Spurious scattered and/or reflected light is absorbed by the colored polymer over the length of the measurement cell, while very little light loss occurs at the coupling windows.
Type:
Grant
Filed:
February 4, 2011
Date of Patent:
May 5, 2015
Assignee:
University of Southampton
Inventors:
Cedric Florian Aymeric Floquet, Hywel Morgan, Vincent Joseph Sieben, Iain Rodney George Ogilvie, Matthew Charles Mowlem
Abstract: An imaging apparatus is disclosed which uses a super-oscillatory lens to obtain sub-diffraction limit resolution. The super-oscillatory lens is arranged to receive a light beam from a light source, the lens having a pre-defined pattern to spatially modulate the light beam in amplitude and/or phase so that it focuses the light beam to a focus at a first focal point having a full width half maximum of less than half the wavelength. Collection optical elements are arranged to focus the first focal point to a second focal point conjugate to the first focal point. An object for imaging is scanned over the first focal point and a detector is arranged to collect light from a collection region centered on the second focal point.
Type:
Grant
Filed:
March 8, 2012
Date of Patent:
April 14, 2015
Assignee:
University of Southampton
Inventors:
Edward Thomas Foss Rogers, Nikolay Ivanovich Zheludev, John E Chad
Abstract: Polymer blends of polypropylene homopolymer and propylene-?-olefin interpolymer. Processes for producing polymeric compositions comprising control-cooling heated blends of polypropylene and propylene-?-olefin interpolymer. Such polymeric compositions can be employed in forming coated wires and cables.
Type:
Application
Filed:
February 22, 2013
Publication date:
March 26, 2015
Applicants:
Dow Global Technologies LLC, GnoSys Global Ltd., University of Southampton
Abstract: An electro-optic device, comprising an insulating layer and a layer of light-carrying material adjacent the insulating layer. The layer of light-carrying material, such as silicon, comprises a first doped region of a first type and a second doped region of a second, different type abutting the first doped region to form a pn junction. The first doped region has a first thickness at the junction, and the second doped region has a second thickness at the junction, the first thickness being greater than the second thickness, defining a waveguide rib in the first doped region for propagating optical signals. Since the position of the junction coincides with the sidewall of the waveguide rib a self-aligned process can be used in order to simplify the fabrication process and increase yield.
Type:
Grant
Filed:
January 20, 2011
Date of Patent:
February 17, 2015
Assignee:
University of Southampton
Inventors:
David Thomson, Frederic Gardes, Graham Reed
Abstract: This invention relates to methods for variant cytosine detection, and kits and probes for variant cytosine detection. In particular the variant cytosine detection is related to detection of methylated cytosine, hydroxymethylated cytosine, carboxycytosine and/or formylcytosine in nucleic acid.
Type:
Application
Filed:
July 7, 2014
Publication date:
February 5, 2015
Applicant:
The University of Southampton
Inventors:
Keith R. Fox, Tom Brown, Scott T. Kimber
Abstract: The present invention relates to a method of labelling biological molecules with 18F, via attachment to fluorine to a macrocyclic metal complex of a non-radioactive metal, where the metal complex is conjugated to the biological molecule. Also provided are pharmaceutical compositions, kits and methods of in vivo imaging.
Type:
Application
Filed:
January 22, 2013
Publication date:
December 25, 2014
Applicants:
UNIVERSITY OF SOUTHAMPTON, GE HEALTHCARE LIMITED
Inventors:
Rajiv Bhalla, Sajinder Kaur Luthra, Gill Reid, I, William Levason
Abstract: The invention relates to the generation of electricity from flowing fluid and in the preferred embodiment to a horizontal axis turbine and generator assembly. The present invention is applicable to water turbines and the invention is described in relation to this application. It is however to be appreciated that it is applicable to wind turbines.
Type:
Application
Filed:
August 9, 2012
Publication date:
September 25, 2014
Applicant:
University of Southampton
Inventors:
Suleiman Mahmoud Sharkh, Alan Fraser, Michael Andrew Yuratich, Stephen Richard Turnock
Abstract: A system for analyzing social media content and for determining the influence types of different social media members is disclosed. The system categorizes users according to their influence on the social media conversation and displays information related to this categorization in schematic form. The popularity of a particular topic can be analyzed to determine when the topic resonates and becomes more popular within the social network. In some embodiments, the categorization of the users and schematic display of information can be conducted in real-time.
Type:
Application
Filed:
November 11, 2013
Publication date:
September 18, 2014
Applicants:
UNIVERSITY OF SOUTHAMPTON, EDELMAN , INC.
Abstract: A redox ammoximation process in which a ketone or aldehyde is reacted with ammonia and oxygen in the presence of a catalyst, wherein: the catalyst is an aluminophosphate based redox catalyst having the qualitative general formula (I) M1M2AlPO-5 (I) in which M1 is at least one transition metal atom having redox catalytic capability; M2 is at least one metal atom in the (IV) oxidation state; M1 and M2 are different from each other; and a proportion of the phosphorous atoms in the M1M2AlPO-5 type structure are replaced by M2 atoms.
Abstract: A metallic ring is made of two metals, wherein one metal forms a major arcuate portion and the other a minor arcuate portion of the ring, thereby forming a thermocouple-type structure as a result of the two inter-metallic junctions. The metallic ring supports a surface plasmon whose energy is matched to the energy, i.e. wavelength, of an incident light beam so that the oscillating electromagnetic field of the light resonates with the plasmon. The resonating plasmon causes a temperature difference to arise between the two inter-metallic junctions in the ring. The different Seebeck coefficients of the two metals results in the temperature difference causing a net current to flow around the ring, which in turn generates a magnetic field. Such a thermoelectric metamaterial ring transforms high frequency optical energy into long duration magnetic radiation pulses in the terahertz range.
Type:
Grant
Filed:
January 3, 2013
Date of Patent:
July 15, 2014
Assignee:
University of Southampton
Inventors:
Nikolay Ivanovich Zheludev, Vassili A Fedotov, Anagnostis Tsiatmas, Francisco Javier Garcia De Abajo, William James Stewart
Abstract: A redox ammoximation process in which a ketone or aldehyde is reacted with ammonia and oxygen in the presence of a catalyst; wherein the catalyst is an aluminophosphate based redox catalyst having at least two different redox catalytic sites comprising different transition metal atoms.
Abstract: A new class of phase change materials has been discovered based on compounds of: Ga; lanthanide; and chalcogenide. This includes compounds of Ga, La, and S (GLS) as well as related compounds in which there is substitution of S with O, Se and/or Te. Moreover, La can be substituted with other lanthanide series elements. It has been demonstrated that this class of materials exhibit low energy switching. For example, the GLS material can provide an optical recording medium with erasability 3-5 dB greater than the erasability of GeSbTe (GST) material which is the standard material for phase change memories.
Type:
Application
Filed:
December 3, 2013
Publication date:
May 15, 2014
Applicant:
University of Southampton
Inventors:
Daniel William HEWAK, Richard J. CURRY, Arshad Khawar MAIRAJ, Robert E. SIMPSON
Abstract: A tunable metamaterial comprising a membrane on which is arranged a two-dimensional array of elements to form a metamaterial, wherein the array is subdivided into blocks of multiple elements, each block being separated from adjacent blocks by a gap to allow each block to be moveable relative to its adjacent blocks. The lattice of the metamaterial and hence its properties are tuned by inducing adjacent blocks to move away from each other or towards each other either in-plane or out-of-plane in a controllable manner in response to an electrical, thermal or optical control signal.
Type:
Grant
Filed:
June 24, 2011
Date of Patent:
May 6, 2014
Assignee:
University of Southampton
Inventors:
Nikolay Ivanovich Zheludev, Eric Plum, Jun-Yu Ou
Abstract: A new class of phase change materials has been discovered based on compounds of: Ga; lanthanide; and chalcogenide. This includes compounds of Ga, La, and S (GLS) as well as related compounds in which there is substitution of S with O, Se and/or Te. Moreover, La can be substituted with other lanthanide series elements. It has been demonstrated that this class of materials exhibit low energy switching. For example, the GLS material can provide an optical recording medium with erasability 3-5 dB greater than the erasability of GeSbTe (GST) material which is the standard material for phase change memories.
Type:
Grant
Filed:
December 20, 2006
Date of Patent:
January 7, 2014
Assignee:
University of Southampton
Inventors:
Daniel William Hewak, Richard J. Curry, Arshad Khawar Mairaj, Robert E. Simpson
Abstract: A sample of nonlinear optical material for use in a nonlinear optical device contains a grating comprising alternating regions of inverted and non-inverted nonlinear coefficient of the material, with the regions separated by boundaries positioned such that the grating can provide quasi-phase matching of a selected nonlinear optical interaction, and compensate for phase mismatch arising from the Gouy phase shift of one or more focused optical beams involved in the interaction. The boundary positions can be calculated for second harmonic generation or optical parametric generation and oscillation.
Type:
Grant
Filed:
January 16, 2009
Date of Patent:
January 7, 2014
Assignee:
University of Southampton
Inventors:
Corin Barry Edmund Gawith, Peter George Robin Smith, Huw Edward Major
Abstract: The invention provides a method of treating a patient having target cells that express FcyRIIb, the method comprising administering (i) an antibody molecule that specifically binds a surface antigen of the target cell, which antibody molecule has an Fc domain capable of binding FcyRIIb; in combination with (ii) an agent that prevents or reduces binding between the Fc domain of the antibody molecule and FcyRIIb; characterized in that the patient is selected on the basis that their target cells express an elevated level of FcyRIIb.
Type:
Application
Filed:
August 19, 2011
Publication date:
September 26, 2013
Applicant:
UNIVERSITY OF SOUTHAMPTON
Inventors:
Mark Cragg, Martin Glennie, Ali Roghanian, Stephen Beers, Peter Johnson, Sean Lim, Bjorn Frendeus, Ingrid Teige
Abstract: A redox ammoximation process in which a ketone or aldehyde is reacted with ammonia and oxygen in the presence of a catalyst, wherein: the catalyst is an aluminophosphate based redox catalyst having the qualitative general formula (I) M1M2AlPO-5 (I) in which M1 is at least one transition metal atom having redox catalytic capability; M2 is at least one metal atom in the (IV) oxidation state; M1 and M2 are different from each other; and a proportion of the phosphorous atoms in the M1M2AlPO-5 type structure are replaced by M2 atoms.
Abstract: A redox ammoximation process in which a ketone or aldehyde is reacted with ammonia and oxygen in the presence of a catalyst; wherein the catalyst is an aluminophosphate based redox catalyst having at least two different redox catalytic sites comprising different transition metal atoms.
Abstract: An optical waveguide device (10) comprises a planar substrate with a lower cladding layer (14), a core layer (16) and an upper cladding layer (18), a groove (20) in the substrate that extends at least into the core layer (16), and a waveguiding channel (22) in the core layer (16), wherein at least a part of the waveguiding channel (22), which may contain a Bragg grating, is sufficiently proximate to the groove (20) in the plane of the substrate for an evanescent field of light propagating in the waveguiding channel (22) to extend laterally into the groove (20). Material contained in the groove modifies the properties of the waveguiding channel, so that a sample of material can be analysed or an active material can be used to modulate the propagating light. The groove (20) can be made before the waveguide (22). The groove (20) can be made by cutting into the substrate with a saw and the waveguide (22) can be made by direct writing in the core layer (16) with an ultraviolet beam.
Type:
Grant
Filed:
March 20, 2008
Date of Patent:
September 17, 2013
Assignee:
University of Southampton
Inventors:
James Christopher Gates, Corin Barry Edmund Gawith, Peter George Robin Smith