Patents Assigned to University of Toronto
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Publication number: 20250145835Abstract: The present disclosure provides a textile coating composition comprising a primer bonding to at least one surface of a textile and a polymer brush bonding to the primer. The primer is of general formula (I) and the polymer brush is of general formula (II). A coated textile comprising a textile coated with the textile coating composition and a method of forming the coated textile are also provided.Type: ApplicationFiled: November 1, 2024Publication date: May 8, 2025Applicant: The Governing Council of the University of TorontoInventors: Kevin Bram GOLOVIN, Sudip Kumar LAHIRI, Zahra AZIMI DIJVEJIN, Weiming LI
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Patent number: 12291794Abstract: Electrosynthesis of oxirane can include contacting a halide electrolyte with an anode and cathode respectively located in anodic and cathodic compartments; supplying olefin reactants into the electrolyte in the anodic compartment, such that the anode generates ethylene chlorohydrin; withdrawing a loaded anodic solution comprising ethylene halohydrin from the anodic compartment, and a loaded cathodic solution comprising OH? ions from the cathodic compartment; and mixing the loaded anodic solution with the loaded cathodic solution under conditions to react ethylene halohydrin with OH— to produce oxirane. The electrocatalyst can include iridium oxide on a titanium substrate, with the iridium oxide provided as nanoparticles on a titanium mesh, and the electrolyte can be aqueous KCl.Type: GrantFiled: March 18, 2021Date of Patent: May 6, 2025Assignee: THE GOVERNING COUNCIL OF THE UNIVERSITY OF TORONTOInventors: Wan Ru Leow, Yanwei Lum, Edward Sargent
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Patent number: 12284654Abstract: Some embodiments of the present disclosure provide a deep-learning-based framework for designing components of a downlink precoding system. The components of such a system include downlink training pilots and channel estimation based on receipt of the downlink training pilots. Another component involves channel measurement and feedback strategy at the user equipment. The components include a precoding scheme designed at the base station based on the feedback from the user equipment.Type: GrantFiled: November 9, 2023Date of Patent: April 22, 2025Assignees: THE GOVERNING COUNCIL OF THE UNIVERSITY OF TORONTO, HUAWEI TECHNOLOGIES CANADA CO., LTD.Inventors: Wei Yu, Foad Sohrabi, Kareem Attiah Alboraie, Mohammadhadi Baligh
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Patent number: 12282668Abstract: Methods and devices for analyzing and updating intermediate representations containing pointers includes compiling one or more source files into intermediate representations (IRs) having pointers, analyzing the IRs, producing transformed IRs comprising updated pointers, and producing object code from the transformed IRs. The device may include one or more non-transitory computer-readable storage devices having computer-executable instructions, when executed, cause a processing structure to perform the actions described relating to pointers. The analysis and updating of pointers may relate to types of bounds to enhance security of the systems in question by preventing erroneous references to memory space by pointers.Type: GrantFiled: January 13, 2023Date of Patent: April 22, 2025Assignees: Huawei Technologies Canada Co., Ltd., The Governing Council of the University of TorontoInventors: Yifei Wang, David Juen Fung Lie, Shengjie Xu
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Patent number: 12272971Abstract: There is described a wireless power transfer system utilizing a new excitation-quadrature-quadrature transmitter pad which includes one excitation coil and at least two decoupled quadrature auxiliary coils. A described resonant tank design method is proposed for constant-current charging and zero phase angle conditions. When there is a lateral misalignment in the receiver pad, the auxiliary coil that is better coupled with the receiver pad conducts more current than the more distant auxiliary coil does, reducing the leakage magnetic field in the surrounding area and/or improving transmission efficiency.Type: GrantFiled: February 9, 2022Date of Patent: April 8, 2025Assignees: INNOVATIONS & PARTNERSHIPS OFFICE UNIVERSITY OF TORONTO, ELEAPPOWER LTD.Inventors: Zhichao Luo, Shuang Nie, Mehanathan Pathmanathan, Peter Waldemar Lehn
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Publication number: 20250108149Abstract: The present application relates to hyaluronic acid (HA) hydrogels comprising divalent cations and hyaluronic acid molecules cross-lined with the divalent cations, and uses thereof. The present application also relates to methods of preparing the HA hydrogels of the present application.Type: ApplicationFiled: September 30, 2024Publication date: April 3, 2025Applicant: The Governing Council of the University of TorontoInventors: Gayatri Prakash, Frank Gu, Shengyan Liu
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Patent number: 12258670Abstract: Electrosynthesis of oxirane can include contacting a halide electrolyte with an anode that includes an electrocatalyst comprising iridium oxide loaded with a period-6 metal oxide and provided on a metal substrate. The cathode can be operated under ORR conditions. The electrochemical system can also be provided as an integrated system that includes CO2 electroreduction to produce ethylene and formation of hypochlorous acid using the electrocatalyst, followed by contact of the ethylene and the hypochlorous acid to form ethylene chlorohydrin which is, in turn, contacted with OH? ions to produce oxirane.Type: GrantFiled: December 21, 2022Date of Patent: March 25, 2025Assignee: THE GOVERNING COUNCIL OF THE UNIVERSITY OF TORONTOInventors: Yuhang Li, Adnan Ozden, Wan Ru Leow, Pengfei Ou, Edward Sargent
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Publication number: 20250082782Abstract: This technology relates to polynucleotides comprising optimized FMR1 open reading frame (ORF) sequences, viral vectors comprising the same, and methods of using the same for delivery of the ORF to a cell or a subject and to treat disorders associated with aberrant expression of FMR1, such as Fragile X syndrome (“FXS”).Type: ApplicationFiled: January 27, 2023Publication date: March 13, 2025Applicants: THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM, THE GOVERNING COUNCIL OF THE UNIVERSITY OF TORONTOInventors: Steven J. GRAY, David R. HAMPSON, Hye Ri KANG, Hayes Ga-Hei WONG, Alexander W.M. HOOPER
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Publication number: 20250075241Abstract: A linear double stranded deoxyribonucleic acid (dsDNA) molecule comprising operatively linked in 5? to 3? direction: a) one or more Ter sites at 5? terminus (“5? Ter”); b) a segment comprising a DNA sequence of interest; and c) one or more Ter sites at 3? terminus (“3? Ter). Also methods of protecting DNA sequences of interest from exonuclease degradation using the DNA constructs of the present disclosure, cells transformed with the DNA construct of the present disclosure and cell-free synthetic biology system comprising a linear dsDNA molecule of the present disclosure.Type: ApplicationFiled: January 27, 2022Publication date: March 6, 2025Applicant: The Governing Council of the University of TorontoInventors: Keith Ian PARDEE, Masoud NOROUZI
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Patent number: 12240909Abstract: Provided are antibodies or fragments thereof having binding specificity to anti-IL-18 receptor alpha or beta. Methods of using the antibodies or fragments thereof for treating and diagnosing diseases such as cancer and inflammatory and autoimmune diseases are also provided.Type: GrantFiled: June 19, 2019Date of Patent: March 4, 2025Assignees: ShanghaiTech University, The Governing Council of the University of TorontoInventors: Sachedv S. Sidhu, Donghui Wu, Guohua James Pan, Shusu Liu, Shane Miersch, Haiming Huang
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Patent number: 12239758Abstract: An adhesive device for biomedical applications is provided comprising a support and one or more water insoluble compounds of structure 1 wherein B is an oligomer derived from a polyester, polyether, polyalkylene glycol, polysilicone or polycarbonate with a MW<10,000 g/mol, Linker L is a urethane, urea bond, or amide bond; Linker L? is a urethane or urea bond, A is a chain extender of Mw?3000 g/mol comprising substituted or unsubstituted alkyl, cycloalkyl and/or aromatic groups, W is a terminal adhesive benzene-1,2-diol derivative or a terminal adhesive benzene-1,2,3-triol derivative, m is 0 or 1; and n is 0, 1, 2, 3 or 4 or a cross-linked polymer formed from said compounds. The compound(s) have a Tg lower than 25° C.Type: GrantFiled: December 21, 2020Date of Patent: March 4, 2025Assignees: THE GOVERNING COUNCIL OF THE UNIVERSITY OF TORONTO, SUNNYBROOK HEALTH SCIENCES CENTREInventors: Paul Santerre, Eli Sone, Michael Floros, Jeffrey Fialkov, Cari Whyne
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Patent number: 12234157Abstract: The present description relates to metal alloy electrocatalysts, preferably composed of Ni and Co as transition metals and Se as a chalcogen. The electrocatalysts can take the form of nanochalcogenides that can be made using cryogenic milling followed by surfactant-assistant milling. The electrocatalysts can be used in the context of water electrolysis or electroreduction of CO2 gas into carbon based products.Type: GrantFiled: December 2, 2020Date of Patent: February 25, 2025Assignees: THE GOVERNING COUNCIL OF THE UNIVERSITY OF TORONTO, TOTALENERGIES ONETECHInventors: Jehad Abed, Steven Thorpe, Edward Sargent
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Publication number: 20250045350Abstract: A storage unit stores one of flow and distance matrices for an assignment problem having an evaluation function represented by a matrix operation of the flow and distance matrices, and a processing unit selects first and second entities from entities to be assigned to destinations, reads at least one first matrix element corresponding to the first and second entities from the stored flow or distance matrix, generates at least one second matrix element for the other of the flow and distance matrices, which is a patterned matrix, based on the first and second entities, calculates a change in the value of the evaluation function resulting from an assignment change of changing the destination of the first or second entity, using the first and second matrix elements, determines based on the change whether to allow the assignment change, and updates an assignment state when determining to allow the assignment change.Type: ApplicationFiled: August 2, 2024Publication date: February 6, 2025Applicants: Fujitsu Limited, THE GOVERNING COUNCIL OF THE UNIVERSITY OF TORONTOInventors: Mohammad BAGHERBEIK, Ali SHEIKHOLESLAMI
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Patent number: 12215370Abstract: Described are methods for generating a reporter molecule in response to a target analyte in a cell-free system. A synthetic biological circuit is used to modify the level of the reporter molecule in response to the presence of the target analyte. The reporter molecule may be glucose or another molecule readily detected using a device such as glucose monitor or other portable sensor. Also provided are kits comprising a cell-free system with a synthetic biological circuit that generates or consumes a reporter molecule in response to a target analyte.Type: GrantFiled: December 21, 2018Date of Patent: February 4, 2025Assignee: The Governing Council of the University of TorontoInventors: Keith Pardee, Evan Amalfitano, Margot Karlikow
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Patent number: 12214052Abstract: A fusion protein comprises a nanocage monomer; and an antibody or fragment thereof linked to the nanocage monomer, the antibody or fragment thereof comprising a first member of a binding pair; wherein a plurality of the fusion proteins self-assemble to form a nanocage in which a plurality of the antibodies or fragments thereof decorate the exterior surface of the nanocage, whereby the first member of the binding pair is exposed for interacting with a second member of a binding pair.Type: GrantFiled: August 3, 2018Date of Patent: February 4, 2025Assignees: The Hospital for Sick Children, The Governing Council of the University of TorontoInventors: Jean-Philippe Julien, Taylor Sicard, Anthony Semesi, Bebhinn Treanor, Tiantian Zhao, Edurne Rujas Diez
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Patent number: 12204452Abstract: A method to obtain a cache miss ratio curve where a memory blocks of a cache have variable block sizes. By stacking sets of counters, each set being for a different block size, a stack distance for variable block sizes can be obtained and used to determine a miss ratio curve. Such curve can then be used to select a cache size that is appropriate for an application without requiring excessive memory. Methods can be used for batches of request, can apply limits to block sizes, and rounding for intermediary block sizes, they can be used with pruning, and their space complexity can be held constant.Type: GrantFiled: November 7, 2022Date of Patent: January 21, 2025Assignees: HUAWEI TECHNOLOGIES CANADA CO., LTD., THE GOVERNING COUNCIL OF THE UNIVERSITY OF TORONTOInventors: Sari Sultan, Kia Shakiba, Albert Lee, Michael Stumm, Ming Chen, Chung-Man Abelard Chow
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Publication number: 20250017856Abstract: A co-formulation comprising: (i) an ionizable colloid forming active substance; (ii) a nucleic acid molecule; and (iii) an amphiphilic molecule. Also, a method of treating a disease or disorder comprising administering the co-formulation to a subject in need, wherein the ionizable colloid-forming active substance and the nucleic acid molecule included in the co-formulation act together in the treatment of the disease or disorder; and a method of manufacturing the co-formulation.Type: ApplicationFiled: July 15, 2024Publication date: January 16, 2025Applicant: THE GOVERNING COUNCIL OF THE UNIVERSITY OF TORONTOInventors: Kai Vincent Slaughter, Molly Sandra Shoichet, Eric Niel Rummens Donders
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Patent number: 12190722Abstract: There is provided a system and method for traffic signal control of a traffic network with a learned model. The method including: receiving sensor readings from the traffic network, the sensor readings including positions and speeds of vehicles approaching each intersection; using a learned dynamics model that takes the sensor readings as input, predicting a plurality of possibilities for position and velocity of the vehicles approaching each intersection in a future timestep; determining a action for the one or more intersections by performing a tree search on the plurality of possibilities and selecting the possibility with a highest action value; and outputting the action to the traffic network for implementation as a traffic control action at the one or more intersections.Type: GrantFiled: June 13, 2022Date of Patent: January 7, 2025Assignee: THE GOVERNING COUNCIL OF THE UNIVERSITY OF TORONTOInventors: Parth Jaggi, Scott Sanner, Baher Abdulhai
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Patent number: 12182621Abstract: A system and method for using sparsity to accelerate deep learning networks. The method includes: communicating a bit vector to a scheduler identifying which values in an input tensor are non-zero; for each lane of the input tensor, determining which values are to be communicated for multiply-accumulate (MAC) operations, the determination including directing performance of one of: communicating the current value in the lane; communicating the next value in the same lane where such value is non-zero; communicating a value from a step ahead in time where such value is non-zero; and communicating a value from a neighboring lane where such value is non-zero; and outputting the values of the MAC operations.Type: GrantFiled: July 16, 2021Date of Patent: December 31, 2024Assignee: THE GOVERNING COUNCIL OF THE UNIVERSITY OF TORONTOInventors: Mostafa Mahmoud, Andreas Moshovos
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Patent number: 12170493Abstract: An innovative power electronic control system suitable for various applications, such as for electric vehicles is provided. The system, in some embodiments, is configured for the purposes of on-board AC fast charging (e.g., single phase or multi-phase) when an object is not in use (e.g., a vehicle is stationary) and use as a drive (e.g., for a vehicle, an EV drivetrain) when in motion. The innovative power electronic control system enables, among others, the ability to obtain fast-charging from existing grid infrastructure.Type: GrantFiled: October 24, 2022Date of Patent: December 17, 2024Assignees: THE GOVERNINING COUNCI OF THE UNIVERSITY OF TORONTO, ELEAPPOWER LTD.Inventors: Peter Lehn, Ruoyun Shi, Theodore Soong