Abstract: There is described novel organo-platinum luminophores comprising a complex of formula I: The luminophores have application as the emissive component in organic light emitting diodes.

Abstract: In one example of the invention a patient display is provided on which a fixation graphic or video is shown in substantially the centre of the display, and then target graphics or video are shown at different positions on the display about the centre. A test subject is positioned in front of the patient display a known distance therefrom, and a camera captures an image of the test subject's eyes, to allow gaze direction determination to be performed. The captured images are displayed to a clinician user by a controlling test application, the clinician making a determination based on the images as to whether the test subject saw a target graphic or video when it was displayed. The clinician user then makes an appropriate input into the controlling test application, which also logs the position at which the target image was displayed.

Abstract: An NMR method is presented having enhanced sensitivity on a compound comprising hyperpolarizable nuclei, in particular applying enhanced PHIP. Polarization is thereby transferred from a prepared fluid, which is enriched with symmetric molecules of a particular spin state (e.g. para-hydrogen enriched), directly to the hyperpolarizable nuclei of a compound, without altering the chemical identity of the compound in this process. Spin transfer is achieved using a template having sites of ordered environment, and the fluid and the compound are brought together in the presence of the template. Polarization transfer to the hyperpolarizable nuclei of the compound is thereby easier to perform and can be applied to a broader scope of compounds.

Abstract: We describe a plant lipase polypeptide and nucleic acids that encode said polypeptide which has homology to a patatin and which has phospholipase and/or triacylglycerol lipase activity.

Abstract: Urothelium is the specialized endothelium that lines much of the mammalian urinary tract. This invention relates to the field of in vitro urothelial culture. Previous methods produce tissue lacking much of the functionality of native urothelium. In this invention, stratified, differentiated mammalian urothelium is produced by passaging urothelial cells through a nutrient medium containing serum, and redispersed, before going on in a like medium to form said urothelium.

Abstract: There is described novel organo-platinum luminophores comprising a complex of formula (I). The luminophores have application as the emissive component in organic light emitting diodes.

Abstract: A method and apparatus are disclosed for simulating wave propagation in an environment. The method includes the steps of, via a first model of the environment generated with a first modelling method, simulating a first response of the environment in a time and/or frequency domain over a first portion of the domain, and via a further model of the environment generated with a further modelling method, simulating a further response of the environment in the time and/or frequency domain over at least one further portion of the domain.

Abstract: We describe a plant lipase polypeptide and nucleic acids that encode said polypeptide which has homology to a patatin and which has phospholipase and/or triacylglycerol lipase activity.

Abstract: The invention relates to a hybrid interfering RNA molecule comprising a duplex RNA and a single stranded DNA molecule and its use in the ablation of mRNA and in polymerase chain reactions.

Abstract: There is described a method of selective observation of non-hydrogenative para-hydrogen induced polarisation (NH-PHIP) as enhanced magnetic resonance signals which comprises separating the thermal and longitudinal spin order states. There is also described a template comprising [Ir(COD)(NHC)(Py)]+, and analogues thereof, for use in a PHIP magnetic resonance technique and a method for its preparation.

Abstract: The present invention relates to an ionic liquid comprising an anion and a cation, wherein the cation is a primary, secondary or tertiary ammonium ion containing a protonated nitrogen atom.

Abstract: There is described a processor for use in the microwave torrefaction of biomass material which comprises, a micronised biomass char material and a method of producing a biomass char material, and a method of producing L-glucosan.

Abstract: We describe transgenic cells transformed with nucleic acid molecules which encode enzymes with desaturase activity and the use of these cells and enzymes in biocatalysis.

Abstract: We describe a plant and plant cell which is modified to enhance the production of plant-derived oil in particular in non-seed tissue and including methods for the processing of plant derived biomass materials.

Abstract: This disclosure relates to a SIRT1 polypeptide and a treatment regime that inhibits the activity of SIRT1 and including a method of diagnosis.

Abstract: There is described a structural material comprising a substrate and a binder characterised in that the binder comprises a bio-silicate and a process for the manufacture thereof.

Abstract: The invention relates to the induction of apoptosis by inhibition of the sirtuin SIRT1 expression, in particular the induction of apoptosis in tumour cells. Materials and methods for inhibiting SIRT1 expression are provided, including RNA interference methods. In particular, the invention provides a method of treating a proliferative disease comprising administering to an individual in need thereof an effective amount of a SIRT1 inhibitor.

Abstract: There is described novel organo-platinum luminophores comprising a complex of formula (I). The luminophores have application as the emissive component in organic light emitting diodes.

Abstract: A method and apparatus for producing an estimate of the acoustic response an environment. The method comprises receiving a first signal, and a second signal including a part of the first signal. The first and second signals are combined to produce a third signal. The first signal is combined with itself to produce a fourth signal. A plurality of weighted means of said third signal are computed and summed to produce a plurality of first summations. A plurality of weighted means of said fourth signal are computed and summed to produce a plurality of second summations. Said estimate is generated from said first and second summations.

Abstract: We describe transgenic cells which are transformed with nucleic acid molecules which encode glucosyltransferase polypeptides involved in phenylpropanoid biosynthesis.