Patents Assigned to University of York
  • Patent number: 8293898
    Abstract: There is described novel organo-platinum luminophores comprising a complex of formula I: The luminophores have application as the emissive component in organic light emitting diodes.
    Type: Grant
    Filed: December 16, 2011
    Date of Patent: October 23, 2012
    Assignee: University of York
    Inventors: Duncan W. Bruce, Valery Kozhevnikov
  • Publication number: 20120154751
    Abstract: In one example of the invention a patient display is provided on which a fixation graphic or video is shown in substantially the centre of the display, and then target graphics or video are shown at different positions on the display about the centre. A test subject is positioned in front of the patient display a known distance therefrom, and a camera captures an image of the test subject's eyes, to allow gaze direction determination to be performed. The captured images are displayed to a clinician user by a controlling test application, the clinician making a determination based on the images as to whether the test subject saw a target graphic or video when it was displayed. The clinician user then makes an appropriate input into the controlling test application, which also logs the position at which the target image was displayed.
    Type: Application
    Filed: August 24, 2010
    Publication date: June 21, 2012
    Applicants: University of York, Cambridge Enterprise Limited
    Inventors: Adar Pelah, Allen Louise Elizabeth, Slater Michael Edward, Jackson Andrew Robert
  • Patent number: 8154284
    Abstract: An NMR method is presented having enhanced sensitivity on a compound comprising hyperpolarizable nuclei, in particular applying enhanced PHIP. Polarization is thereby transferred from a prepared fluid, which is enriched with symmetric molecules of a particular spin state (e.g. para-hydrogen enriched), directly to the hyperpolarizable nuclei of a compound, without altering the chemical identity of the compound in this process. Spin transfer is achieved using a template having sites of ordered environment, and the fluid and the compound are brought together in the presence of the template. Polarization transfer to the hyperpolarizable nuclei of the compound is thereby easier to perform and can be applied to a broader scope of compounds.
    Type: Grant
    Filed: June 17, 2008
    Date of Patent: April 10, 2012
    Assignee: University of York
    Inventors: Simon Benedict Duckett, Gary George Green, Paul Ian Elliott, Joaquin Lopez-Serrano
  • Patent number: 8133729
    Abstract: Urothelium is the specialized endothelium that lines much of the mammalian urinary tract. This invention relates to the field of in vitro urothelial culture. Previous methods produce tissue lacking much of the functionality of native urothelium. In this invention, stratified, differentiated mammalian urothelium is produced by passaging urothelial cells through a nutrient medium containing serum, and redispersed, before going on in a like medium to form said urothelium.
    Type: Grant
    Filed: July 28, 2003
    Date of Patent: March 13, 2012
    Assignee: The University of York
    Inventors: William Richard Cross, Jennifer Southgate
  • Patent number: 8106193
    Abstract: There is described novel organo-platinum luminophores comprising a complex of formula (I). The luminophores have application as the emissive component in organic light emitting diodes.
    Type: Grant
    Filed: September 29, 2008
    Date of Patent: January 31, 2012
    Assignee: University of York
    Inventors: Duncan W. Bruce, Valery Kozhevnikov
  • Publication number: 20120016640
    Abstract: A method and apparatus are disclosed for simulating wave propagation in an environment. The method includes the steps of, via a first model of the environment generated with a first modelling method, simulating a first response of the environment in a time and/or frequency domain over a first portion of the domain, and via a further model of the environment generated with a further modelling method, simulating a further response of the environment in the time and/or frequency domain over at least one further portion of the domain.
    Type: Application
    Filed: December 9, 2008
    Publication date: January 19, 2012
    Applicant: The University of York
    Inventor: Damian Murphy
  • Patent number: 8093452
    Abstract: We describe a plant lipase polypeptide and nucleic acids that encode said polypeptide which has homology to a patatin and which has phospholipase and/or triacylglycerol lipase activity.
    Type: Grant
    Filed: June 9, 2006
    Date of Patent: January 10, 2012
    Assignee: University of York
    Inventor: Peter Eastmond
  • Patent number: 8067572
    Abstract: The invention relates to a hybrid interfering RNA molecule comprising a duplex RNA and a single stranded DNA molecule and its use in the ablation of mRNA and in polymerase chain reactions.
    Type: Grant
    Filed: May 24, 2006
    Date of Patent: November 29, 2011
    Assignee: The University of York
    Inventors: Josephine Anne Milner, Michael Gait, Ming Jiang, Andrei Arzumanov
  • Patent number: 7951994
    Abstract: We describe transgenic cells transformed with nucleic acid molecules which encode enzymes with desaturase activity and the use of these cells and enzymes in biocatalysis.
    Type: Grant
    Filed: February 17, 2005
    Date of Patent: May 31, 2011
    Assignee: The University of York
    Inventors: Ian Graham, Thierry Tonon
  • Patent number: 7863436
    Abstract: The invention relates to the induction of apoptosis by inhibition of the sirtuin SIRT1 expression, in particular the induction of apoptosis in tumour cells. Materials and methods for inhibiting SIRT1 expression are provided, including RNA interference methods. In particular, the invention provides a method of treating a proliferative disease comprising administering to an individual in need thereof an effective amount of a SIRT1 inhibitor.
    Type: Grant
    Filed: February 11, 2005
    Date of Patent: January 4, 2011
    Assignee: The University of York
    Inventor: Anne Josephine Milner
  • Patent number: 7826640
    Abstract: There is provided a hierarchical shadow detection system for color aerial images. The system performs well with highly complex images as well as images having different brightness and illumination conditions. The system consists of two hierarchical levels of processing. The first level involves, pixel level classification, through modeling the image as a reliable lattice and then maximizing the lattice reliability using the EM algorithm. Next, region level verification, through further exploiting the domain knowledge is performed. Further analyses show that the MRF model based segmentation is a special case of the pixel level classification model. A quantitative comparison of the system and a state-of-the-art shadow detection algorithm clearly indicates that the new system is highly effective in detecting shadow regions in an image under different illumination and brightness conditions.
    Type: Grant
    Filed: April 29, 2008
    Date of Patent: November 2, 2010
    Assignee: State University New York
    Inventors: Jian Yao, ZhongFei (Mark) Zhang
  • Patent number: 7826629
    Abstract: A microphone having an optical component for converting the sound-induced motion of the diaphragm into an electronic signal using a diffraction grating. The microphone with inter-digitated fingers is fabricated on a silicon substrate using a combination of surface and bulk micromachining techniques. A 1 mm×2 mm microphone diaphragm, made of polysilicon, has stiffeners and hinge supports to ensure that it responds like a rigid body on flexible hinges. The diaphragm is designed to respond to pressure gradients, giving it a first order directional response to incident sound. This mechanical structure is integrated with a compact optoelectronic readout system that displays results based on optical interferometry.
    Type: Grant
    Filed: January 19, 2006
    Date of Patent: November 2, 2010
    Assignee: State University New York
    Inventors: Ronald N. Miles, F. Levent Degertekin
  • Patent number: 7822193
    Abstract: A method and apparatus for producing an estimate of the acoustic response an environment. The method comprises receiving a first signal, and a second signal including a part of the first signal. The first and second signals are combined to produce a third signal. The first signal is combined with itself to produce a fourth signal. A plurality of weighted means of said third signal are computed and summed to produce a plurality of first summations. A plurality of weighted means of said fourth signal are computed and summed to produce a plurality of second summations. Said estimate is generated from said first and second summations.
    Type: Grant
    Filed: March 18, 2005
    Date of Patent: October 26, 2010
    Assignee: The University of York
    Inventors: Yuriy Zakharov, Timothy Conrad Tozer
  • Patent number: 7705202
    Abstract: This invention relates to nucleic acid molecules which comprise nucleic acid sequences which encode enzymes involved in the biosynthesis of n-3 fatty acids, particularly docosahexanoic acid (DHA), or variants thereof; polypeptides encoded by said nucleic acids; cells transfected with said nucleic acid sequences and products comprising said nucleic acid sequences, polypeptides and/or cells.
    Type: Grant
    Filed: March 17, 2003
    Date of Patent: April 27, 2010
    Assignee: The University of York
    Inventors: Ian Alexander Graham, Thierry Tonon
  • Patent number: 7689043
    Abstract: A camera A produces a 3D natural image B which is re-oriented and repositioned at N to predetermined parameters. Different processes C, D, E extract different features from the image to provide different processed images. The data space occupied by the processed images is reduced, for example by Principle Component Analysis, at F, G, H and the reduced processed images are combined at O to provide an image key I representative of the image B. The image key I is compared at J with stored image keys L of known images, and the output comparison is sorted at K to produce a final list M of potential matches. In a verification process, just a single image key L may be compared. The processed images at C, D, E may alternatively be combined prior to a single subspace reduction and/or optimisation method. 2D data may be combined with or used instead of the 3D data.
    Type: Grant
    Filed: October 11, 2004
    Date of Patent: March 30, 2010
    Assignee: University of York
    Inventors: James Austin, Nicholas Pears, Thomas Heseltine
  • Patent number: 7662583
    Abstract: We describe glycosyltransferase nucleic acids and proteins isolatable from Arabidopsis thaliana, transgenic cells expressing said glycosyltransferases, and bioreactors comprising said transgenic cells together with nutrient medium for supporting the growth of said cell that includes at least one exogenous substrate which is a substrate for said glycosyltransferase, and wherein said nutrient medium does not include an exogenous supply of UDP-glucose.
    Type: Grant
    Filed: May 24, 2004
    Date of Patent: February 16, 2010
    Assignee: The University of York
    Inventors: Eng-Kiat Lim, Dianna Bowles
  • Publication number: 20090311731
    Abstract: We describe a microbial cell, typically a bacterial cell, genetically engineered to produce a modified sugar nucleotide, for example UDP glucuronic acid, and the use of the modified sugar to transfer glucuronic acid to small acceptor molecules.
    Type: Application
    Filed: May 25, 2007
    Publication date: December 17, 2009
    Applicant: The University of York
    Inventor: Eng Kiat Lim
  • Publication number: 20090233343
    Abstract: We describe fusion proteins comprising a bacterial immunity polypeptide and their use in affinity purification of protein complexes.
    Type: Application
    Filed: March 13, 2006
    Publication date: September 17, 2009
    Applicant: University of York
    Inventors: Colin Kleanthous, Theonie Georgiou
  • Publication number: 20080221218
    Abstract: The present invention relates to synthetic receptors, products and methods which are useful in relation to the binding of phosphates for example in water purification and renal dialysis systems.
    Type: Application
    Filed: August 15, 2006
    Publication date: September 11, 2008
    Applicant: The University of York
    Inventors: Hubertus Franciscus Martinus Nelissen, David Kelham Smith
  • Publication number: 20080209597
    Abstract: The invention relates to transgenic cells which have been transformed with nucleic acids encoding glycosyltransferase polypeptides (GTases) and vectors for use in transformation of said cells.
    Type: Application
    Filed: December 28, 2007
    Publication date: August 28, 2008
    Applicant: The University Of York
    Inventors: Diana Joy Bowles, Yi Li, Eng-Kiat Lim