Patents Assigned to University of York
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Patent number: 8293898Abstract: There is described novel organo-platinum luminophores comprising a complex of formula I: The luminophores have application as the emissive component in organic light emitting diodes.Type: GrantFiled: December 16, 2011Date of Patent: October 23, 2012Assignee: University of YorkInventors: Duncan W. Bruce, Valery Kozhevnikov
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Publication number: 20120154751Abstract: In one example of the invention a patient display is provided on which a fixation graphic or video is shown in substantially the centre of the display, and then target graphics or video are shown at different positions on the display about the centre. A test subject is positioned in front of the patient display a known distance therefrom, and a camera captures an image of the test subject's eyes, to allow gaze direction determination to be performed. The captured images are displayed to a clinician user by a controlling test application, the clinician making a determination based on the images as to whether the test subject saw a target graphic or video when it was displayed. The clinician user then makes an appropriate input into the controlling test application, which also logs the position at which the target image was displayed.Type: ApplicationFiled: August 24, 2010Publication date: June 21, 2012Applicants: University of York, Cambridge Enterprise LimitedInventors: Adar Pelah, Allen Louise Elizabeth, Slater Michael Edward, Jackson Andrew Robert
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Patent number: 8154284Abstract: An NMR method is presented having enhanced sensitivity on a compound comprising hyperpolarizable nuclei, in particular applying enhanced PHIP. Polarization is thereby transferred from a prepared fluid, which is enriched with symmetric molecules of a particular spin state (e.g. para-hydrogen enriched), directly to the hyperpolarizable nuclei of a compound, without altering the chemical identity of the compound in this process. Spin transfer is achieved using a template having sites of ordered environment, and the fluid and the compound are brought together in the presence of the template. Polarization transfer to the hyperpolarizable nuclei of the compound is thereby easier to perform and can be applied to a broader scope of compounds.Type: GrantFiled: June 17, 2008Date of Patent: April 10, 2012Assignee: University of YorkInventors: Simon Benedict Duckett, Gary George Green, Paul Ian Elliott, Joaquin Lopez-Serrano
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Patent number: 8133729Abstract: Urothelium is the specialized endothelium that lines much of the mammalian urinary tract. This invention relates to the field of in vitro urothelial culture. Previous methods produce tissue lacking much of the functionality of native urothelium. In this invention, stratified, differentiated mammalian urothelium is produced by passaging urothelial cells through a nutrient medium containing serum, and redispersed, before going on in a like medium to form said urothelium.Type: GrantFiled: July 28, 2003Date of Patent: March 13, 2012Assignee: The University of YorkInventors: William Richard Cross, Jennifer Southgate
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Patent number: 8106193Abstract: There is described novel organo-platinum luminophores comprising a complex of formula (I). The luminophores have application as the emissive component in organic light emitting diodes.Type: GrantFiled: September 29, 2008Date of Patent: January 31, 2012Assignee: University of YorkInventors: Duncan W. Bruce, Valery Kozhevnikov
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Publication number: 20120016640Abstract: A method and apparatus are disclosed for simulating wave propagation in an environment. The method includes the steps of, via a first model of the environment generated with a first modelling method, simulating a first response of the environment in a time and/or frequency domain over a first portion of the domain, and via a further model of the environment generated with a further modelling method, simulating a further response of the environment in the time and/or frequency domain over at least one further portion of the domain.Type: ApplicationFiled: December 9, 2008Publication date: January 19, 2012Applicant: The University of YorkInventor: Damian Murphy
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Patent number: 8093452Abstract: We describe a plant lipase polypeptide and nucleic acids that encode said polypeptide which has homology to a patatin and which has phospholipase and/or triacylglycerol lipase activity.Type: GrantFiled: June 9, 2006Date of Patent: January 10, 2012Assignee: University of YorkInventor: Peter Eastmond
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Patent number: 8067572Abstract: The invention relates to a hybrid interfering RNA molecule comprising a duplex RNA and a single stranded DNA molecule and its use in the ablation of mRNA and in polymerase chain reactions.Type: GrantFiled: May 24, 2006Date of Patent: November 29, 2011Assignee: The University of YorkInventors: Josephine Anne Milner, Michael Gait, Ming Jiang, Andrei Arzumanov
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Patent number: 7951994Abstract: We describe transgenic cells transformed with nucleic acid molecules which encode enzymes with desaturase activity and the use of these cells and enzymes in biocatalysis.Type: GrantFiled: February 17, 2005Date of Patent: May 31, 2011Assignee: The University of YorkInventors: Ian Graham, Thierry Tonon
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Patent number: 7863436Abstract: The invention relates to the induction of apoptosis by inhibition of the sirtuin SIRT1 expression, in particular the induction of apoptosis in tumour cells. Materials and methods for inhibiting SIRT1 expression are provided, including RNA interference methods. In particular, the invention provides a method of treating a proliferative disease comprising administering to an individual in need thereof an effective amount of a SIRT1 inhibitor.Type: GrantFiled: February 11, 2005Date of Patent: January 4, 2011Assignee: The University of YorkInventor: Anne Josephine Milner
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Patent number: 7826640Abstract: There is provided a hierarchical shadow detection system for color aerial images. The system performs well with highly complex images as well as images having different brightness and illumination conditions. The system consists of two hierarchical levels of processing. The first level involves, pixel level classification, through modeling the image as a reliable lattice and then maximizing the lattice reliability using the EM algorithm. Next, region level verification, through further exploiting the domain knowledge is performed. Further analyses show that the MRF model based segmentation is a special case of the pixel level classification model. A quantitative comparison of the system and a state-of-the-art shadow detection algorithm clearly indicates that the new system is highly effective in detecting shadow regions in an image under different illumination and brightness conditions.Type: GrantFiled: April 29, 2008Date of Patent: November 2, 2010Assignee: State University New YorkInventors: Jian Yao, ZhongFei (Mark) Zhang
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Patent number: 7826629Abstract: A microphone having an optical component for converting the sound-induced motion of the diaphragm into an electronic signal using a diffraction grating. The microphone with inter-digitated fingers is fabricated on a silicon substrate using a combination of surface and bulk micromachining techniques. A 1 mm×2 mm microphone diaphragm, made of polysilicon, has stiffeners and hinge supports to ensure that it responds like a rigid body on flexible hinges. The diaphragm is designed to respond to pressure gradients, giving it a first order directional response to incident sound. This mechanical structure is integrated with a compact optoelectronic readout system that displays results based on optical interferometry.Type: GrantFiled: January 19, 2006Date of Patent: November 2, 2010Assignee: State University New YorkInventors: Ronald N. Miles, F. Levent Degertekin
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Patent number: 7822193Abstract: A method and apparatus for producing an estimate of the acoustic response an environment. The method comprises receiving a first signal, and a second signal including a part of the first signal. The first and second signals are combined to produce a third signal. The first signal is combined with itself to produce a fourth signal. A plurality of weighted means of said third signal are computed and summed to produce a plurality of first summations. A plurality of weighted means of said fourth signal are computed and summed to produce a plurality of second summations. Said estimate is generated from said first and second summations.Type: GrantFiled: March 18, 2005Date of Patent: October 26, 2010Assignee: The University of YorkInventors: Yuriy Zakharov, Timothy Conrad Tozer
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Patent number: 7705202Abstract: This invention relates to nucleic acid molecules which comprise nucleic acid sequences which encode enzymes involved in the biosynthesis of n-3 fatty acids, particularly docosahexanoic acid (DHA), or variants thereof; polypeptides encoded by said nucleic acids; cells transfected with said nucleic acid sequences and products comprising said nucleic acid sequences, polypeptides and/or cells.Type: GrantFiled: March 17, 2003Date of Patent: April 27, 2010Assignee: The University of YorkInventors: Ian Alexander Graham, Thierry Tonon
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Patent number: 7689043Abstract: A camera A produces a 3D natural image B which is re-oriented and repositioned at N to predetermined parameters. Different processes C, D, E extract different features from the image to provide different processed images. The data space occupied by the processed images is reduced, for example by Principle Component Analysis, at F, G, H and the reduced processed images are combined at O to provide an image key I representative of the image B. The image key I is compared at J with stored image keys L of known images, and the output comparison is sorted at K to produce a final list M of potential matches. In a verification process, just a single image key L may be compared. The processed images at C, D, E may alternatively be combined prior to a single subspace reduction and/or optimisation method. 2D data may be combined with or used instead of the 3D data.Type: GrantFiled: October 11, 2004Date of Patent: March 30, 2010Assignee: University of YorkInventors: James Austin, Nicholas Pears, Thomas Heseltine
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Patent number: 7662583Abstract: We describe glycosyltransferase nucleic acids and proteins isolatable from Arabidopsis thaliana, transgenic cells expressing said glycosyltransferases, and bioreactors comprising said transgenic cells together with nutrient medium for supporting the growth of said cell that includes at least one exogenous substrate which is a substrate for said glycosyltransferase, and wherein said nutrient medium does not include an exogenous supply of UDP-glucose.Type: GrantFiled: May 24, 2004Date of Patent: February 16, 2010Assignee: The University of YorkInventors: Eng-Kiat Lim, Dianna Bowles
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Publication number: 20090311731Abstract: We describe a microbial cell, typically a bacterial cell, genetically engineered to produce a modified sugar nucleotide, for example UDP glucuronic acid, and the use of the modified sugar to transfer glucuronic acid to small acceptor molecules.Type: ApplicationFiled: May 25, 2007Publication date: December 17, 2009Applicant: The University of YorkInventor: Eng Kiat Lim
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Publication number: 20090233343Abstract: We describe fusion proteins comprising a bacterial immunity polypeptide and their use in affinity purification of protein complexes.Type: ApplicationFiled: March 13, 2006Publication date: September 17, 2009Applicant: University of YorkInventors: Colin Kleanthous, Theonie Georgiou
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Publication number: 20080221218Abstract: The present invention relates to synthetic receptors, products and methods which are useful in relation to the binding of phosphates for example in water purification and renal dialysis systems.Type: ApplicationFiled: August 15, 2006Publication date: September 11, 2008Applicant: The University of YorkInventors: Hubertus Franciscus Martinus Nelissen, David Kelham Smith
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Publication number: 20080209597Abstract: The invention relates to transgenic cells which have been transformed with nucleic acids encoding glycosyltransferase polypeptides (GTases) and vectors for use in transformation of said cells.Type: ApplicationFiled: December 28, 2007Publication date: August 28, 2008Applicant: The University Of YorkInventors: Diana Joy Bowles, Yi Li, Eng-Kiat Lim