Abstract: The fouling state of a polymeric membrane within the high pressure housing of a spiral wound or a hollow fiber membrane module is determined. An ultra sonic transducer positioned with its emitting face in physical engagement with the outer surface of the housing is pulse energized by a pulser/receiver device. A membrane echo signal is detected by a receiver of the pulser/receiver device. A reference echo signal indicative of a fouled or an unfouled state of the membrane is compared to the echo signal to determine the membrane fouling state. The echo to reference comparing step can be based upon comparing amplitude domain signals, comparing time-domain signals, comparing combinations of amplitude domain and time-domain signals, and comparing transformations of amplitude domain and time-domain signals.

Abstract: This invention provides a phase modulator comprising an electro-optically rotatable smectic liquid crystal half-wave retarder in combination with a cholesteric liquid crystal circular polarizer. Rotation of the half-wave retarder varies the phase delay of the modulator. A polarizing interferometer is provided utilizing the phase modulator of this invention in combination with a second cholesteric circular polarizer and a linear polarizer. A tunable Fabry-Perot resonator which does not require ordinary mirrors is provided utilizing the phase modulator of this invention in combination with a second cholesteric circular polarizer.

Abstract: The present invention is directed to novel telomerase nucleic acids and amino acids. In particular, the present invention is directed to nucleic acid and amino acid sequences encoding various telomerase protein subunits and motifs, including the 123 kDa and 43 kDa telomerase protein subunits of Euplotes aediculatus, and related sequences from Schizosaccharomyces, Saccharomyces sequences, and human telomerase. The present invention is also directed to polypeptides comprising these telomerase protein subunits, as well as functional polypeptides and ribonucleoproteins that contain these subunits.

Abstract: A method and apparatus for demixing an aqueous solution is provided. The aqueous solution has at least two aqueous phases. The method comprises applying acoustic energy to the aqueous solution. The apparatus comprises a mechanism for applying acoustic energy to the aqueous solution until the aqueous solution is demixed to clarity.

Abstract: The present invention provides a method for growing atomic layer thin films on functionalized substrates at room temperature using catalyzed binary reaction sequence chemistry. Specifically, the atomic layer films are grown using two half-reactions. Catalysts are used to activate surface species in both half-reactions thereby enabling both half-reactions to be carried out at room temperature.

Abstract: A method for producing a high temperature superconductor system having the composition TlBiBaCaCuO. The system exhibits a T.sub.c of at least 116 K. The method includes the steps of mixing compounds including Tl, Bi, Ba, Ca, Cu, and O to create a mixture. The mixture is heated. The mixture is then cooled.

Abstract: An optical system for providing an in-focus, extended depth of field image on a projection surface includes an encoded mask or light encoder for preceding the light to include object information (or, equivalently, information about the desired image), and an extended depth of field (EDF) mask, for extending the depth of field of the projection system. In addition to including object information, the encoded mask encodes the light from the light source to account for the variations introduced by the EDF mask in extending the depth of field, so that no post processing is required.

Abstract: The present invention relates to formulations and methods for preventing and treating liver injury and fibrosis in cholestasis. This is accomplished by the administration of a composition which includes selected antioxidants.

Abstract: A new class of variable length, nonlinear feedback shift registers (NLFSR's) is disclosed that uses data-dependent dynamically allocated taps to filter digital information reversibly, flexibly, and rapidly. This class of NLFSR's has been succinctly realized in terms of a multi-parameter family of nonlinear, discrete difference equations that operate on digital data of variable length. Each individual NLFSR is characterized by a collection of integer `parameter functions` and `boundary condition functions` denoted .PI..sub.T for an integer T.gtoreq.1. A concrete description of an exemplary set .PI..sub.T is given in the text. Given an input sequence to the NLFSR, the final output sequence is another sequence defined by the values of the parameter and boundary condition functions, and a new reversible (or invertible) nonlinear mathematical rule that transforms a sequence of integers into a different sequence of integers.

Abstract: This invention provides achromatic liquid crystal compound retarders, achromatic polarization switches, and achromatic shutters using the liquid crystal compound retarders. It further provides achromatic variable retardance smectic liquid crystal retarders. The compound retarder of this invention comprises a central liquid crystal retarder unit and two external passive retarders positioned in series with and on either side of the liquid crystal retarder unit. The liquid crystal retarder unit comprises either (1) a rotatable smectic liquid crystal half-wave retarder or (2) first and second liquid crystal variable retarders having retardance switchable between zero and half-wave. The external passive retarders are equal in retardance and orientation to each other. Design equations determine the retardance of the external elements and their orientation relative to the central retarder to obtain a particular achromatic retardance for the compound structure.

Abstract: A process for modifying surfaces of zeolites and molecular sieve membranes to decrease effective pore size for separation of materials includes atomic layer controlled vapor or liquid deposition. The atomic layer controlled deposition process steps include (i) exposing the surface to a metal atom coordinated with ligand groups having bonds that are hydrolyzable to form molecular bonded structures on the surface, which structures comprise the metal atoms coordinated with the ligand group or a modified ligand group and then (ii) hydrolyzing the bonds and possibly, but not necessarily, cross-linking the bonds in the ligand or modified ligand group.

Abstract: A programmable hologram generator comprises a layered structure of a pixelated VLSI chip, a reflective ferroelectric liquid crystal that is physically disposed on the VLSI chip, and a photorefractive crystal that is physically disposed on the liquid crystal. The VLSI chip is controlled by a computer wherein holograms are digitally stored. The reflective state of the individual pixel areas of the liquid crystal are controlled or selected by this computer control of the VLSI chip. A desired hologram is written into the photorefractive crystal by a reference beam that illuminates the photorefractive crystal, and by an illumination beam that is reflected from the selected pixels of the liquid crystal and thereafter interferes with the reference beam. The hologram that is written into the photorefractive crystal is a function of the control of the reflective state of the pixels of the liquid crystal, as this reflective state is in turn controlled by the pixels of the VLSI chip.

Abstract: A condenser system for controlling vapor concentration contained in a flowing airstream is provided. The flowing airstream has an initial temperature upon entering the condenser system and a final temperature upon exiting the condenser system. The condenser system has a membrane member allowing mass transfer of the vapor therethrough with the airstream contacting the membrane member. A condensing member diffuses the vapor from the airstream through the membrane member. An insulating layer is positioned between the membrane member and the condensing member with the insulating layer inhibiting heat transfer between the flowing airstream and the condensing member wherein the final temperature of the airstream is substantially equal to the initial temperature of the airstream.

Abstract: An anti-aliasing filter for use in an incoherent imaging system reduces the resolution of the optical image to prevent aliasing, without requiring a reduction in the amount of light captured by the system, and without adversely affecting image quality or requiring complex optical systems. The filter modifies the wavefront of light emanating from the object in a curved, non-symmetrical manner, in such a way as to effectively attenuate spatial frequencies in the image to values less than some desired small level for all spatial frequencies beyond a predetermined bandlimit. The filter may be reflective or transmissive.

Abstract: A robust method of stabilizing a diode laser frequency to an atomic transition is provided. The method employs Zeeman shift to generate an anti-symmetric signal about a Doppler-broadened atomic resonance, and, therefore, offers a large recapture range as well as high stability. The frequency of a 780 nm diode laser, stabilized to such a signal in Rb, drifts less than 0.5 MHz.sub.pk-pk (one part in 10.sup.9) in thirty-eight hours. This tunable frequency lock may be inexpensively constructed, requires little laser power, rarely loses lock, and may be extended to other wavelengths by using different atomic species.

Abstract: The invention provides a method of treating heart failure. The method comprises administering a positive inotropic agent and a .beta.-adrenergic receptor antagonist in a specific manner.

Abstract: The present invention provides the yeast genes SAS2, SAS3 and ESA1 and the proteins encoded thereby. SAS2, SAS3 and ESA1 genes of members of the genus Saccharomyces are provided, particularly the SAS2, SAS3 and ESA1 genes of S. cerevisiae. Also provided are yeast SAS2, SAS3 and ESA1 coding sequences. Specifically provided are the SAS2, SAS3 and ESA1 coding sequences of members of the genus Saccharomyces, and more specifically of S. cerevisiae. Genes of this invention comprise protein coding sequences as well as the regulatory regions that control expression of the encoded protein. Of most interest are SAS2, SAS3, and ESA1 genes of yeast including those of the genus Saccharomyces which are 90% or more homologous to the corresponding genes of S. cerevisiae. Specifically provided are DNA constructs comprising purified and isolated DNA molecules comprising SAS2, SAS3 or ESA1 coding sequences that encode proteins from a strain of S. cerevisiae.

Abstract: The present invention includes the identification and isolation of a nucleic acid molecule encoding a dibasic amino acid processing endoprotease from CD4+ T-lymphocytes as well as a protein encoded by that nucleic acid molecule. The present invention also includes related nucleic acid molecules and proteins encoded by such nucleic acid molecules as well as recombinant molecules and recombinant cells that include nucleic acid molecules of the present invention. The present invention also includes use of such nucleic acid molecules and proteins to develop therapeutic compositions that enhance or inhibit dibasic amino acid processing endoprotease activity.

Abstract: Provided is a method for preparing a true, homogeneous solution of a pharmaceutical substance dissolved in an organic solvent in which the pharmaceutical substance is not normally soluble. Solubilization is obtained by forming a hydrophobic ion pair complex involving the pharmaceutical substance and an amphiphilic material. The resulting organic solution may be further processed to prepare pharmaceutical powders. A biodegradable polymer may be co-dissolved with the pharmaceutical substance and the amphiphilic material and may be incorporated into a pharmaceutical powder. A preferred method for preparing pharmaceutical powders is to subject the organic solution to gas antisolvent precipitation using a supercritical gas antisolvent such as carbon dioxide. Also provided is a method for making hollow particles having a fiber-like shape which would provide enhanced retention time in the stomach if ingested by a human or animal host.

Abstract: This invention provides a vision system that increases the field of view of an electronic binocular system without degrading image quality or requiring extremely large format sensors or displays. The vision system comprises an imaging device coupled with a viewing device. The imaging device comprises a compression lens and an image sensor. The viewing device comprises an image display and a decompression lens. The compression lens matches the optical distortion to the human visual acuity curve for field positions greater than an angle .theta.. Below angle .theta. there is substantially no distortion. The optimum angle .theta. depends on the application. For an average individual viewing a landscape the angle .theta. is about 10.degree.. For different viewing objects, the optimum angle .theta. varies from about 5.degree. to about 15.degree.. The image sensor can be infrared sensitive for infrared viewing.