Abstract: The present disclosure belongs to the field of materials with metal structures, and specifically relates to a preparation method for a nano-oxide dispersion strengthened steel. The method includes mixing a ferrochromium alloy, a ferrotungsten alloy, a ferroalloy containing a rare earth element, an oxygen source and a reduced iron powder to obtain a mixture; wrapping the mixture in a steel strip, and conducting drawing reducing to obtain a flux-cored wire; and conducting arc additive manufacturing on the flux-cored wire on a substrate, and then conducting heat treatment to obtain the nano-oxide particle dispersion strengthened steel.

Abstract: An organic light emitting diode having a substrate, a first electrode, a hole transporting layer proximate the first electrode, a second electrode, an electron transporting layer proximate the second electrode, and an emissive layer between the hole transporting layer and the electron transporting layer. The emissive layer includes a square planar tetradentate platinum or palladium complex, and excimers formed by two or more of the complexes are aligned such that emitting dipoles of the excimers are substantially parallel to a surface of the substrate.

Abstract: The present disclosure discloses a three-dimensional co-prime cubic array direction-of-arrival estimation method based on a cross-correlation tensor, mainly solving the problems of multi-dimensional signal structured information loss and Nyquist mismatch in existing methods and comprising the following implementing steps: constructing a three-dimensional co-prime cubic array; carrying out tensor modeling on a receiving signal of the three-dimensional co-prime cubic array; calculating six-dimensional second-order cross-correlation tensor statistics; deducing a three-dimensional virtual uniform cubic array equivalent signal tensor based on cross-correlation tensor dimension merging transformation; constructing a four-dimensional virtual domain signal tensor based on mirror image augmentation of the three-dimensional virtual uniform cubic array; constructing a signal and noise subspace in a Kronecker product form through virtual domain signal tensor decomposition; and acquiring a direction-of-arrival estimation

Abstract: The present disclosure describes an intervertebral disk replacement system. The system can include a tissue-engineered intervertebral disc that is combined with a bioresorbable stabilization system for structural guidance. The system can prevent or reduce intervertebral disk implant displacement and can increase the stiffness when compared to the implantation of the intervertebral disk implant without the stabilization system.

Abstract: The present invention is directed to compounds, compositions and methods for preventing, treating or curing hepatitis B (HBV) infection in human subjects or other animal hosts. The compounds are as also pharmaceutically acceptable, salts, prodrugs, and other derivatives thereof as pharmaceutical compositions and methods for treatment, prevention or eradication of HBV infection.

Abstract: The present invention is primarily directed to provide a new process capable of performing direct conversion of or induction from a somatic cell to brown adipocytes with low molecular weight compounds, without performing artificial gene transfer. The present invention includes, for example, a process for producing brown adipocytes by direct differentiation induction from somatic cells, comprising a step of culturing a somatic cell in a serum-free differentiation induction medium in the presence of a selective PPAR? agonist and a cAMP inducer. According to the present invention, direct conversion of or induction from somatic cells to brown adipocytes can be effectively performed without gene transfer. The brown adipocytes obtained by the present invention are useful as regenerative medicine, models of human brown adipocytes and human beige cells, and the like.

Abstract: Disclosed is a psychomotor ability assessment method based on multi-target tracking paradigm, which includes the following steps: analyzing research data of psychomotor ability, determining a plurality of measurement dimensions of psychomotor ability, and designing an experimental task paradigm based on the plurality of measurement dimensions, wherein the experimental task paradigm is used for representing a level of the plurality of measurement dimensions; designing evaluation schemes of the measurement dimension based on the experimental task paradigm; evaluating a ability dimension of a person to be detected based on the evaluation schemes, collecting and processing evaluation data, and calculating a weight value of the ability dimension to obtain an evaluation result of the psychomotor ability.

Abstract: Provided herein are high-throughput methods for genetic barcoding and analysis, e.g., for tagging each biomaterial apsule with a barcode cell. These barcode cells are derived from patient samples, and thus embody natural human genetic variation. Also provided are SNP panels that can be used as genetic barcodes to identify the identity of a cell.

Abstract: Provided herein are non-naturally occurring, broadly reactive antigens derived from influenza viruses or avian infectious bronchitis virus (IBV) that are immunogenic and capable of eliciting a broadly reactive immune response, e.g., a broadly reactive neutralizing antibody response, directed against influenza virus antigens or IBV antigens following introduction into a subject. Also provided are non-naturally, broadly reactive immunogens, vaccines, virus-like particles (VLPs) and compositions comprising the immunogens and vaccines. Methods of generating an immune response in a human or non-human subject by administering the immunogens, vaccines, VLPs, or compositions thereof are provided. In particular, the immunogens comprise broadly reactive hemagglutinin (HA) protein antigens of influenza virus strains, such as H1, H2, H3, H5, or H7, or of IBV. The immunogens also comprise broadly reactive viral neuraminidase (NA) protein antigens.

Abstract: Ferromagnetic materials are disclosed that comprise at least one Dirac half metal material. In addition, Dirac half metal materials are disclosed, wherein the material comprises a plurality of massless Dirac electrons. In addition, ferromagnetic materials are disclosed that includes at least one Dirac half metal material, wherein the material comprises a plurality of massless Dirac electrons, wherein the material exhibits 100% spin polarization, and wherein the plurality of electrons exhibit ultrahigh mobility. Spintronic devices and heterostructures are also disclosed that include a Dirac half metal material.

Abstract: The invention provides, for the first time, strategies to inhibit the killing of transplanted cells by activated polymorphonuclear cells (PMNs) of the recipient. Multiple different modes for PMN inhibition are provided and one or more agents effectively utilized every mode of action. The combination of two or more of those agents with different modes of action synergistically improved the efficacy of PMN inhibition without exerting toxic side effects on the survival of the target cells. The cells may be pluripotent cells, including hypoimmune pluripotent cells (HIP), ABO blood type O Rhesus Factor negative HIP cells (HIPO?), or derivatives thereof. The cells may also be alpha 1 antitrypsin (A1AT) secreting cells.

Abstract: A multi-lumen implantable device configured to deliver a therapeutic agent to a selected portion of a blood vessel is disclosed. As one example, an implantable device includes a first lumen configured to flow blood from an upstream end to a downstream end of the device when implanted in a blood vessel; a second lumen fluidly separated from the first lumen and configured for introducing a therapeutic agent to a selected, first portion of a wall of the blood vessel, between the upstream end and the downstream end of the device; and at least one sealing member configured to block the therapeutic agent from entering a second portion of the wall of the blood vessel, between the upstream end and the downstream end of the device.

Abstract: Disclosed is a testing device for measuring interfacial shear properties between fibers and media, including a main body, which is a rectangular plate-like structure with L-shaped plates provided at the bottom ends of the main body, a connecting rod provided at a top right of the main body, a groove provided at the top of the main body; and four rotating grooves are provided inside the groove. The rotating grooves are cylindrical structures with raised centers at both ends; and a mounting piece is installed above the left end of the main body; a magnet of a displacement micrometer is connected to a tension trolley, a high-definition camera is turned on, weights are added into a loading bucket and the fiber movement is observed until the fiber is pulled out or sliding friction occurs, and then the camera is stopped and accurate data is tested.

Abstract: The present invention relates to human IgG Fc domain variants with improved effector function and uses thereof.

Abstract: A system and method for predicting failures of rod pumps using a scaled load ratio is configured to: optimize the size of a rolling window, the upper and lower bounds of the normal range of the scaled load ratio, an alert period, and an alert frequency ratio; receive data of a current maximum/minimum loads on a surface rod, and a current speed; remove outliers showing an abnormality; scale the current maximum/minimum loads on the surface rod using the maximum/minimum loads on the surface rod in normal operation; calculate a scaled load ratio; calculate the average of scaled load ratios in the rolling window; determine whether the average of scaled load ratios is in the normal range, and classify the values as normal and abnormal events; calculate the ratio of the abnormal events in the alert period, and generate an alert when the calculated ratio exceeds the alert frequency ratio; and monitor a pump state using the pump failure prediction system.

Abstract: Various embodiments of systems and methods for inductive anomaly detection on attributed networks using a graph neural layer to learn anomaly-aware node representations and further employ generative adversarial learning to detect anomalies among new data are disclosed herein.

Abstract: A fluorescence image analyzer has an imaging unit for capturing a first image containing at least a part of a region of a cell as an imaging target for a plurality of cells in a sample in which a target site on a chromosome is labeled with a fluorescent dye, and a second image including fluorescence generated from a fluorescent dye labeling the target site of the cell of the first image. The processing unit selects a plurality of test cells having specific morphological characteristics to be tested from a plurality of cells based on at least the first image, and extracts the bright spots of fluorescence generated from the fluorescent dye. The processing unit identifies cells with chromosomal abnormalities and/or cells without chromosomal abnormalities based on the extracted bright spots, and generates information related to the ratio of cells with chromosomal abnormalities relative to the test cells.

Abstract: The present disclosure is directed towards a method of treating a disease or condition associated with gut inflammation. The present disclosure comprises administering, to a patient in need thereof, a composition comprising oxygen-scavenging membrane fragments or membrane vesicles. In some embodiments, membrane vesicles are derived from bacteria. In some embodiments, membrane vesicles are derived from the cytoplasmic membranes of Escherichia coli, Salmonella typhimurium, Gluconobacter oxydans, Pseudomonas aeruginosa, or Acetobacter.

Abstract: A device for detecting whether a plurality of electronic components having one or more defective electronic components includes: an energy source generating energy and transferring the generated energy to the plurality of electronic components in a non-contact manner to cause the plurality of electronic components to vibrate; a mechanical resonance detector detecting vibration resonances of the plurality of electronic components; and a post-processing processor comparing the detected vibration resonances of the plurality of electronic components with a reference vibration resonance of a normal product to determine whether the plurality of electronic components have one or more defective electronic components and then extracting determined information.

Abstract: The present disclosure provides an ultrasound therapy system and a dose control method. The system includes: a control device; a first ultrasound irradiation device configured to generate multiple groups of ultrasound irradiation doses driven by the control device and conduct ultrasound irradiation on a cell culture device with multiple groups of abnormally proliferating living cells; a characterization image capture device configured to capture performance characteristic data of living cells in the cell culture device, where the control device is further configured to determine an ultrasound irradiation dose corresponding to at least one group of abnormally proliferating living cells with a cell target characteristic characterization as a target ultrasound irradiation dose according to the performance characteristic data; and a second ultrasound irradiation device configured to conduct ultrasound irradiation of the target ultrasound irradiation dose on a living organism with abnormal proliferation.