Patents Assigned to University
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Patent number: 11578121Abstract: The invention relates to anti-EGF like domain multiple 6 antibody (anti-EGFL6 antibody) and cancer detection (or diagnosis) and treatment using the anti-EGFL6 antibody. The present invention creates anti-EGFL6 antibodies, particularly, a single-chain antibody fragments (scFv) and humanized antibody, which have ability in binding to EGFL6 and in inhibiting angiogenesis and cancer cell growth.Type: GrantFiled: September 28, 2018Date of Patent: February 14, 2023Assignees: Taipei Medical University, Changhua Christian Medical Foundation Changhua Christian Hospital, National Research institute of Chinese Medicine, Ministry of Health and WelfareInventors: Yu-Ching Lee, Shiow-Lin Pan, Wei-Chun Huangfu, Tsui-Chin Huang, Po-Li Wei, Han-Li Huang, Chun-Chun Cheng, Cheng-Chiao Huang, Keng-Chang Tsai, Kun-Tu Yeh, Ting-Yi Sung, Fu-Ling Chang
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Patent number: 11579335Abstract: The present disclosure describes various embodiments of systems, apparatuses, and methods for large-scale processing of weather-related data. For one such system, the system comprises a database of weather-related data providing from a plurality of weather monitoring stations and a plurality of interconnected processors for coordinating a data processing job for processing a set of input weather-related data from the database. Accordingly, the input data comprises sensor data from an array of weather monitoring stations positioned on an open shoreline during a hydrodynamic event, weather model data for the hydrodynamic event, and at least one of air-craft reconnaissance data or satellite reconnaissance data regarding the hydrodynamic event, wherein the plurality of interconnected processors are configured to assimilate the input data and generate, using machine learning, an improved weather prediction model for the hydrodynamic event. Other systems, apparatuses, and methods are also provided.Type: GrantFiled: May 21, 2021Date of Patent: February 14, 2023Assignees: University of Florida Research Foundation, Inc., Clarkson University, Woods Hole Oceanographic InstitutionInventors: Forrest J. Masters, Pedro L. Fernandez-Caban, Brian M. Phillips, Christopher C. Ferraro, Britt Raubenheimer, Wei-Ting Lu
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Patent number: 11577980Abstract: Disclosed is a coating made of an organic material on a mold for glass molding. The coating comprises CrxWyN(1-x-y), where 0.15<x<0.4, and 0.2?y?0.45. The coating has excellent high temperature resistance and anti-adhesion properties, thus being a promising coating material for molds.Type: GrantFiled: September 24, 2019Date of Patent: February 14, 2023Assignees: No.59 Institute of China Ordnance Industry, University of Science and Technology Liaoning, Shenzhen UniversityInventors: Qiang Chen, Zhiwen Xie, Feng Gong, Xinfang Huang, Kangsen Li, Yuanyuan Wan
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Patent number: 11580203Abstract: A system for authenticating a user attempting to access a computing device or a software application executing thereon. A data storage device stores one or more digital images or frames of video of face(s) of authorized user(s) of the device. The system subsequently receives from a first video camera one or more digital images or frames of video of a face of the user attempting to access the device and compares the image of the face of the user attempting to access the device with the stored image of the face of the authorized user of the device. To ensure the received video of the face of the user attempting to access the device is a real-time video of that user, and not a forgery, the system further receives a first photoplethysmogram (PPG) obtained from a first body part (e.g., a face) of the user attempting to access the device, receives a second PPG obtained from a second body part (e.g., a fingertip) of the user attempting to access the device, and compares the first PPG with the second PPG.Type: GrantFiled: April 26, 2019Date of Patent: February 14, 2023Assignee: Arizona Board of Regents on behalf of Arizona State UniversityInventors: Yimin Chen, Yanchao Zhang
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Patent number: 11576949Abstract: The invention features compositions featuring (a) one or more of connective tissue growth factor (CTGF) and human C-terminal CTGF peptide; and (b) one or more of insulin and IGF-1; and methods of using such compositions to reduce cardiac tissue damage associated with an ischemic event or to enhance engraftment of a cell in a cardiac tissue.Type: GrantFiled: April 24, 2020Date of Patent: February 14, 2023Assignee: The University of Vermont and State Agriculture CollegeInventor: Jeffrey Spees
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Patent number: 11576957Abstract: Provided herein are vaccine composition comprising an antigen conjugated to a capsid, wherein the capsid comprises wild type or native sequence. Provided herein are also vaccine composition comprising an antigen conjugated to a capsid, wherein said capsid comprises at least one mutation, such as a non-natural mutation. Such compositions are useful in the treatment and prevention of pathogenic infections, inflammatory diseases, and neurodegenerative disease, and cancer, among others.Type: GrantFiled: April 23, 2018Date of Patent: February 14, 2023Assignee: Board of Trustees of Michigan State UniversityInventors: Xuefei Huang, Suttipun Sungsuwan
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Patent number: 11580631Abstract: Dynamic thin film interferometry is a technique used to non-invasively characterize the thickness of thin liquid films that are evolving in both space and time. Recovering the underlying thickness from the captured interferograms, unconditionally and automatically is still an open problem. A compact setup is provided employing a snapshot hyperspectral camera and the related algorithms for the automated determination of thickness profiles of dynamic thin liquid films. The technique is shown to recover film thickness profiles to within 100 nm of accuracy as compared to those profiles reconstructed through the manual color matching process. Characteristics and advantages of hyperspectral interferometry are discussed including the increased robustness against imaging noise as well as the ability to perform thickness reconstruction without considering the absolute light intensity information.Type: GrantFiled: February 15, 2021Date of Patent: February 14, 2023Assignee: The Board of Trustees of the Leland Stanford Junior UniversityInventors: Gerald G. Fuller, Vineeth Chandran Suja
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Patent number: 11581733Abstract: The present disclosure provides techniques for estimating network states using asynchronous measurements by leveraging network inertia. For example, a device configured in accordance with the techniques of the present disclosure may receive electrical parameter values corresponding to at least one first location within a power network and determine, based on the electrical parameter values and a previous estimated state of the power network, an estimated value of unknown electrical parameters that correspond to a second location within the power network. The device may further cause at least one device within the power network to modify operation based on the estimated value of the unknown electrical parameters. The leveraging of network inertia may obviate the need for probabilistic models or pseudo-measurements.Type: GrantFiled: November 12, 2020Date of Patent: February 14, 2023Assignees: Alliance for Sustainable Energy, LLC, The Regents of the University of Colorado, a body corporateInventors: Guido Cavraro, Andrey Bernstein, Emiliano Dall'Anese
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Patent number: 11576871Abstract: The disclosure provides cysteamine salt and cystamine formulations comprising enteric coatings. The disclosure also provides composition for use in treating diseases and disorders that can be treated with cysteamine.Type: GrantFiled: November 16, 2016Date of Patent: February 14, 2023Assignee: The Regents of the University of CaliforniaInventor: Ranjan Dohil
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Patent number: 11581402Abstract: A method and apparatus include an n-doped layer having a first applied charge, and a p?-doped layer having a second applied charge. The p?-doped layer may be positioned below the n-doped layer. A p+-doped buffer layer may have a third applied charge and be positioned below the p?-doped layer. The respective charges at each layer may be determined based on a dopant level and a physical dimension of the layer. In one example, the n-doped layer, the p?-doped layer, and the p+-doped buffer layer comprise a lateral semiconductor manufactured from silicon carbide (SiC).Type: GrantFiled: September 5, 2019Date of Patent: February 14, 2023Assignee: Board of Regents, The University of Texas SystemInventor: Qin Huang
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Patent number: 11579175Abstract: A pulse measurement device is provided, including a first signal source, a second signal source, two microwave resonators, two mixers, and a signal processing unit. The first signal source and the second signal source output a first high-frequency signal and a second high-frequency signal, respectively. Each of the microwave resonators generates an electric field according to the first high-frequency signal, and senses a variation in the electric field which is interfered by a pulse to obtain a sensing signal. Each of the mixers is coupled to one of the microwave resonators, to mix the sensing signal and the second high-frequency signal to output a down-converted signal. The signal processing unit respectively demodulates amplitudes of the down-converted signals of the two mixers to obtain amplitude signals.Type: GrantFiled: March 25, 2021Date of Patent: February 14, 2023Assignee: National Cheng Kung UniversityInventors: Ching-Lung Yang, Chia-Hui Chen
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Patent number: 11578137Abstract: This invention relates to inhibition of the complement signaling using an anti-C5 antibody. Specifically, the invention relates to methods of treating a complement-mediated disease or complement-mediated disorder in an individual by contacting the individual with an anti-C5 antibody.Type: GrantFiled: March 6, 2018Date of Patent: February 14, 2023Assignee: The Trustees of the University of PennsylvaniaInventors: Wenchao Song, Sayaka Sato, Takashi Miwa, Damodar Gullipalli
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Patent number: 11577248Abstract: A biosensor detector device is disclosed suitable for use in measuring membrane fluidity or membrane permeability. The biosensor detector device is formed of a solid substrate having a lipid bilayer compatible surface, a multi-lamellar lipid membrane structure derived from a biological cell and localized on the lipid bilayer compatible surface, an aqueous layer interposed between each lipid bilayer of the multi-lamellar lipid membrane structure. The biological membrane is derived from human red blood cells and localized on the lipid bilayer compatible surface. An electrode forming all or part of the lipid bilayer compatible surface may be used to detect disruptions in the multi-lamellar lipid membrane structure and hemolytic activity in a test sample.Type: GrantFiled: December 21, 2018Date of Patent: February 14, 2023Assignee: McMaster UniversityInventors: Maikel Rheinstadter, Sebastian Himbert, Richard Alsop, Jose Moran-Mirabal, Sokunthearath Saem, Dawn Bowdish
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Patent number: 11582399Abstract: A system to process images includes a light source configured to emit a first illumination pattern onto one or more first portions of a scene. The system also includes an image sensor configured to capture light reflected from the scene in response to the emitted first illumination pattern. The system also includes an optimizer configured to perform raytracing of the light reflected from the scene. The system further includes a processor operatively coupled to the optimizer. The processor is configured to determine a parameter of a surface of the scene based on the raytracing, cause the light source to emit a second illumination pattern onto one or more second portions of the scene based at least in part on the parameter of the surface, and refine the parameter of the surface of the scene based on additional raytracing performed on reflected light from the second illumination pattern.Type: GrantFiled: March 7, 2019Date of Patent: February 14, 2023Assignee: Northwestern UniversityInventors: Nathan S. Matsuda, Oliver Strider Cossairt, Jesse Chang, Christopher Gezon
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Patent number: 11578251Abstract: The invention relates to the technical field of oil and gas drilling, and discloses an amphiphilic block polymer ultralow-permeability agent and an intelligent temporary plugging type water-based drilling fluid. The ultralow-permeability agent contains a structural unit provided by styryl hydrophobic monomer, maleic anhydride and acrylamide; the drilling fluid contains two or more of water, sodium bentonite, Pac-Lv, the ultralow-permeability agent, calcium carbonate, one-way plugging agent, white asphalt and barite which are stored in a mixed manner or independently stored.Type: GrantFiled: March 16, 2022Date of Patent: February 14, 2023Assignee: China University of Petroleum (Beijing)Inventors: Yinbo He, Guancheng Jiang, Lili Yang, Tengfei Dong, Bin Tan, Rongchao Cheng, He Shi, Jianguo Zhang, Tie Geng, Jiansheng Luo, Dongmin Jia, Kai Wang, Chunlin Xie, Wuquan Li, Xiaoqing Li
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Patent number: 11578355Abstract: The present invention relates to a nanoplasmonic biosensor capable of label-free multiplex detection of disease markers in blood with high selectivity and sensitivity and a method for detecting disease markers using the nanoplasmonic biosensor. The nanoplasmonic biosensor of the present invention enables label-free multiplex detection of miRNAs as disease markers in blood with high selectivity and sensitivity. Therefore, the nanoplasmonic biosensor of the present invention can be effectively used for the diagnosis of miRNA-related diseases and clinical applications.Type: GrantFiled: March 22, 2019Date of Patent: February 14, 2023Assignee: Korea University Research and Business FoundationInventors: Sang Jun Sim, Jong-Uk Lee, Woo-hyun Kim
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Patent number: 11577193Abstract: The present invention provides a heat-driven adsorption vacuum dehumidification system including a vapor adsorption apparatus having a water permeable hydrophilic membrane separating the apparatus into at least a feed section and a low-pressure or vacuum section (evaporator), and providing a water vapor pressure difference to extract moisture from the air flowing through the apparatus into the evaporator, followed by adsorption in an adsorption chamber, and subsequently desorbed when acted as a desorption chamber to form water vapor which is condensed in a condenser. Adsorption and desorption chambers inter-change periodically to form a complete system cycle. Heating of chamber/compartment can be from waste heat or a renewable source in the absence of any electricity supplied externally. Related method for using a heat-driven adsorption vacuum dehumidification system to remove moisture from the air is also provided.Type: GrantFiled: August 27, 2021Date of Patent: February 14, 2023Assignee: City University of Hong KongInventors: Kwong Fai Fong, Chun Kwong Lee
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Patent number: 11577975Abstract: There is provided a method for controlling bio-slimes in a clean circulating water system through a physical-chemical-superconducting high gradient magnetic separation coupling process. An inorganic composite flocculant is added to circulating water to gather Zoogloea in the circulating water with micro-nano particles in hydrosol through demulsification to form alum floc. The resulting water passes through a superconducting high gradient magnetic separation system. A magnetic field strength of the superconducting high gradient magnetic separation system and flow rate of the circulating water are controlled to generate strong magnetic flocculation to allow floc to grow, such that the Zoogloea in the circulating water wraps the micro-nano particles to separate the Zoogloea from water.Type: GrantFiled: July 3, 2020Date of Patent: February 14, 2023Assignees: University of Science and Technology Beijing, Beijing Mild Technology Co., Ltd.Inventors: Suqin Li, Shuaishuai Han, Xin Zhao, Guohong Xiong
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Patent number: 11580512Abstract: A smart street parking management system includes a smart street parking meter a smart cloud parking management server connected to the smart street parking meter through a wireless networking technology and configured to regularly receive parking information of a vehicle parked on a smart street parking grid and status information of the smart street parking meter uploaded by the smart street parking meter. The status information of the smart street parking meter includes an empty-space status of the street parking grid detected by the smart street parking meter and a battery status of a rechargeable battery of the smart street parking meter. The parking information of the vehicle includes the plate number of the vehicle, the parking fee of the vehicle, and a payment status of the parking fee of the vehicle.Type: GrantFiled: May 15, 2020Date of Patent: February 14, 2023Assignee: National Formosa UniversityInventors: Chi-Chia Sun, Yong-Ye Lin
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Patent number: 11578929Abstract: A passive heat switch device is disclosed that includes a casing defining a closed channel, as well as a passive thermal actuator and liquid slug positioned inside the closed channel. The closed channel includes a heat conducting region made of a heat conducting material and an insulating region made of an insulating material. The passive thermal actuator is thermally coupled to the heat conducting material of the heat conducting region and extends into the insulating region of the closed channel. The passive thermal actuator deforms when an actuator temperature falls within a switching temperature range. The liquid slug is positioned within the closed channel and contacts at least a portion of the passive thermal actuator and the closed channel and is configured to move along the closed channel between the insulating region and the thermally conductive region in response to deformation of the passive thermal actuator.Type: GrantFiled: July 13, 2021Date of Patent: February 14, 2023Assignee: Washington UniversityInventors: Patricia Weisensee, Mehran Abolghasemibizaki, Junhui Li