Abstract: The present disclosure relates to an oligopeptide. The oligopeptide includes an amino acid sequence. The amino acid sequence includes a binding motif, and the binding motif has a specific amino acid sequence. The present disclosure also relates to a testing kit including the oligopeptide and a medical composition including the oligopeptide.

Abstract: Provided herein is an inhibitor for decreasing cellular levels X-box-binding protein 1 variant 1 (Xv1) in a cancer cell and a method for decreasing Xv1 in a cancer cell by contacting the cancer cell with this inhibitor. Also provided is a pharmaceutical composition for treating a cancer and a method for treating a cancer by administering this composition. In addition there is provided a kit for targeting Xv1 with at least one Xv1 inhibitor, at least one pharmaceutically acceptable carrier and a means for detecting the Xv1 protein or mRNA.

Abstract: Methods and systems are provided for rendering photo-realistic images of a subject or an object using a differentiable neural network for predicting indirect light behavior. In one example, the differentiable neural network outputs a volumetric light map comprising a plurality of spherical harmonic representations. Further, using a reflectance neural network, roughness and scattering coefficients associated with the subject or the object is computed. The volumetric light map, as well as the roughness and scattering coefficients are the utilized for rendering a final image under one or more of a desired lighting condition, desired camera view angle, and/or with a desired visual effect (e.g., expression change).

Abstract: In one aspect, the present disclosure provides organic semiconductors (OSNTs) as well as high-performance electrochemical devices based on the present OSNTs for the production of micro and nano-scale actuators. The present OSNTs may be used in several applications, including movable and implantable interface devices, such as flexible neural microelectrodes.

Abstract: The invention discloses a multi-threshold segmentation method for medical images based on an improved salp swarm algorithm. A two-dimensional histogram is established by means of a grayscale image of a medical image and a non-local mean image, then a salp swarm algorithm is used to determine thresholds selected by a Kapur entropy-based threshold method, and the salp swarm algorithm is improved and mutated by an individual-linked mutation strategy during the threshold selection process to avoid local optimization, so that the segmentation effect on the medical image is optimized; and the method has the advantages of good robustness and high accuracy.

Abstract: The present disclosure belongs to the field of petroleum engineering, and specifically relates to a subsea Christmas tree re-prediction method integrating Kalman filter and Bayesian network. The subsea Christmas tree re-prediction method integrating Kalman filter and Bayesian network includes three steps: digital twin model establishment, degradation process re-prediction model establishment, and remaining useful life calculation model establishment.

Abstract: Some embodiments of the disclosure provides polyacrylonitrile (PAN) and a preparation method and use thereof. The method includes the following steps. Mixing raw materials for polymerization to obtain a suspension comprising the PAN. The raw materials include an acrylonitrile monomer, a first auxiliary monomer, a second auxiliary monomer, a polymerization medium, an initiator, a chain transfer agent, and a settling agent. Removing unreacted monomers and unreacted polymerization medium in the suspension to obtain the PAN. After subsequent removal of monomers, removal of a polymerization medium, washing, and drying, a PAN powder is obtained. In some embodiments, the preparation method of the PAN has a wide adjustable range of a PAN copolymerization composition, a low viscosity of a polymerization system, a high concentration of a polymerized monomer, and a strong anti-scaling ability.

Abstract: A nanostructure for isolating or concentrating extracellular vesicles or a pathogen, includes a transferrin family protein linked on magnetic nanoparticles. The nanostructure includes a transferrin family protein, and thus has selectivity for a pathogen or extracellular vesicles capable of binding to the transferrin family protein, and the synthesized nanostructure is positively (+) charged. The nanostructure includes magnetic nanoparticles, a target material is easily and simply isolated from other materials by magnetism when a magnetic field is applied.

Abstract: The disclosure relates to a powdery filament composition for 3D printing, a 3D printer, and a method of additively manufacturing an object by the 3D printer, and more particularly to a powdery filament composition for 3D printing, which is suitable for home use because it does not produce toxic substances, a 3D printer, the size of which is suitable for home use because it does not require high power energy, high-temperature processing and the like conditions for additive manufacturing, and a method of additively manufacturing an object by the 3D printer.

Abstract: Disclosed is an ultra-micro voice coil motor based on Micro-Electro-Mechanical System (MEMS) three-dimensional coil. The ultra-micro voice coil motor based on MEMS three-dimensional coil comprises a yoke, where an accommodating cavity is formed in the yoke, and a tongue is arranged in the accommodating cavity of the yoke; and two permanent magnets symmetrically arranged at a top and a bottom of the accommodating cavity; the three-dimensional coil is provided with an iron core slot, and the tongue of the yoke passes through the iron core slot to be in clearance fit with the three-dimensional coil; one end of the yoke is provided with a baffle, same poles of two magnets face each other, and a stator of the voice coil motor is the three-dimensional coil or the yoke and the permanent magnets.

Abstract: A biosensor that includes a semiconductor active region; a sensing region configured to contact a fluid; and multiple electrodes that comprise decoupling electrodes and additional electrodes. The decoupling electrodes may be configured, wherein operating in a first mode, to prevent a formation of a top conductive channel within the semiconductor active region; and wherein the additional electrodes are configured, wherein operating in the first mode, to independently control (i) one or more properties of one or more other conductive channels formed within the semiconductor active region, and (ii) a Debye length at an interface between the sensing region and the fluid.

Abstract: Methods and systems for deconvoluting tumor ecosystems for personalized cancer therapy are disclosed. Generally, human cancers exhibit large variation in behavior between and within patients, which is in large part related to cellular composition. Identifying cell types can identify specific types of tumors and/or cancers present in an individual. Further embodiments generally describe identifying therapies from clinical trials to which the tumor or cancer ecotypes respond, thus providing personalized therapies based on the identified cancer or tumor type.

Abstract: The present disclosure relates to bacteria and bacteria-associated volatile organic compounds, and to their use in agriculture.

Abstract: A transparent electrode with a transparent substrate and a composite layer disposed thereon, wherein the composite layer includes a graphene layer and a plurality of nanoparticles, wherein the nanoparticles are embedded in the graphene layer and extend through a thickness of the graphene layer, and wherein the plurality of nanoparticles are in direct contact with the transparent substrate and a gap is present between the graphene layer and the transparent substrate.

Abstract: A dielectric-grating waveguide free-electron laser device generating coherent or laser-like radiation is provided. An electron beam propagates next to a dielectric waveguide with a built-in grating structure to generate highly confined coherent or laser-like radiation in the waveguide through the Bragg resonance, the backward-wave resonance, or the Fabry-Perot resonance provided by the grating-waveguide structure. The dielectric-grating waveguide can be made of linear optical materials or nonlinear optical materials or combination of linear and nonlinear optical materials to enable versatile functionalities, such as laser generation, laser-wavelength conversion, and laser signal processing. Owing to the build-up of the laser modes inside the dielectric waveguide, coherent or laser-like Smith-Purcell radiation is also generated above the grating via coupling and bunching of the electrons with the surface mode fields.

Abstract: Provided are iridium complexes having a ligand LA of Formula I Also provided are formulations comprising these iridium complexes. Further provided are OLEDs and related consumer products that utilize these iridium complexes.

Abstract: Described herein are expression vectors encoding the Wolbachia protein WalE1. Also described are insects transformed with an expression vector of the present disclosure, and progeny thereof. Also described are methods for improving Wolbachia replication and transmission in its insect host by overexpressing WalE1 in the insect host. Improved Wolbachia replication and transmission provides for insect population control and pathogen resistance in insects, which can reduce disease transmission.

Abstract: A system that provides the ability to integrate both diagnostic tissue detection and therapeutic tissue treatment functionality in an implantable medical device (IMD), such as a graft or stent. The system comprises: an IMD having a pair of electrodes configured to contact biological tissue at an implant location; an impedance sensor configured to detect data indicative of a complex impedance of the biological tissue at the electrodes for a plurality of frequencies; and an analysis device configured to determine one or more cell types in the biological tissue using information indicative of variation in phase and magnitude of the complex impedance across the plurality of frequencies. The system may include a signal generator for applying a treatment signal to the same electrodes.

Abstract: The disclosed embodiments relate to multimodal imaging system comprising a fiber-coupled fluorescence imaging system, which operates based on ultra-violet (UV) excitation light, and a fiber-coupled optical coherence tomography (OCT) imaging system. The multimodal imaging system also includes a fiber optic interface comprising a single optical fiber, which facilitates light delivery to a sample-of-interest and collection of returned optical signals for both the fluorescence imaging system and the OCT imaging system. During operation of the system, the single optical fiber carries both UV light and coherent infrared light through two concentric light-guiding regions, thereby facilitating generation of precisely co-registered optical data from the fluorescence imaging system and the OCT imaging system.

Abstract: The present invention provides benzamide compounds, compositions containing the benzamides, and use of the benzamides for inhibiting androgen receptor (AR) and/or aldo-keto reductase family 1 member C3 (AKR1C3). Also described herein methods for the treatment of hormone-mediated diseases and conditions, including hormone-related cancers such as castration resistant prostate cancer.