Abstract: Provided herein are methods and a device for collecting biological samples from a subject. In particular, the present disclosure relates to a device designed to specifically capture samples within the target areas of a patient for specific cell collection for particular diagnosis.

Abstract: A composite nanomaterial of ZnO impregnated by, e.g., a green copper phthalocyanine compound (CuPc) can be an efficient solar light photocatalyst for water remediation. The composite may include hollow shell microspheres and hollow nanospheres of CuPc-ZnO. CuPc may function as a templating and/or structure modifying agent, e.g., for forming hollow microspheres and/or nanospheres of ZnO particles. The composite can photocatalyze the degradation of organic pollutants such as crystal violet (CV) and 2,4-dichlorophenoxyacetic acid as well as microbes in water under solar light irradiation. The ZnO-CuPc composite can be stable and recyclable under solar irradiation.

Abstract: Provided is a compound including a first ligand LA of Formula I, In Formula I, moiety A is a monocyclic ring or a multicyclic fused ring system; one of X1, X2, and X3 is C and is connected to X4; one of X1, X2, and X3 is N and is coordinated to a metal M; and the remaining one of X1, X2, and X3 is CR or N; X4 is C or N; Y is a divalent linking group; each R, R?, RA, and RB is independently hydrogen or a General Substituent; each of K1 and K2 is independently direct bond, O, or S; and metal M is selected from the group consisting of Os, Ir, Pd, Pt, Cu, Ag, and Au. Formulations, OLEDs, and consumer products including the same are also provided.

Abstract: Batteries having a metal interlayer that acts as an ion conductor are provided, as well as methods of forming the same. The metal interlayer can include, for example, palladium, platinum, iridium, rhodium, ruthenium, osmium, gold, silver, or a combination thereof, and can act as a conductor while also inhibiting the transport of other species that would produce byproduct films and cause capacity degradation in the battery.

Abstract: An embodiment in accordance with the present invention provides a device and method for the treatment of urethral stricture. The present invention places and holds a graft at an incised urethral stricture site for 5-21 days, while the graft adherences to the incised urethral stricture site. A device of the present invention includes a delivery component, a graft carrier component, and a removal component. In some embodiments, the delivery and removal components may be combined into the same device. The delivery component, the graft carrier component, and the removal component are all configured to enter and exit the urethra without trauma. A method according to an embodiment of the present invention includes harvesting a graft, loading the graft onto the graft carrier component, introducing the delivery device into the urethra with the graft carrier component and graft loaded, and delivering of the graft to the incised urethral stricture site.

Abstract: A passive UHF (Ultra High Frequency, 902-928 MHz) RFID-based fabric (such as a diaper) moisture sensor is low-cost, user-friendly, reusable, washable, environment-friendly and comes with an extended on-body read range of 3.6 meters with baby diapers and 4.4 meters with adult diapers. The external reader unit is connected to the internet or a local network, and may automatically notify the parents or caregivers as soon as the presence of moisture is detected.

Abstract: A Group-III nitride light emitting device that utilizes scattering of hot carriers generated by Auger recombination from an externally electrically-driven, relatively narrow band gap carrier generation region into a relatively wide band gap carrier recombination region, such that the relatively wide band gap carrier recombination region of the Group-III nitride light emitting device is internally electrically injected by the hot carriers generated in the externally electrically-injected relatively narrow band gap carrier generation region. The device is used for generation of incoherent light (a light-emitting diode) or coherent light (a laser diode).

Abstract: Provided herein are methods and a device for collecting biological samples. In particular, the present disclosure relates to a device designed to specifically capture samples within the target areas of a patient for specific cell collection for particular diagnosis.

Abstract: Cystine analogs that improve the solubility of L-cystine in urine for treatment of cystinuria and which have the structure: and pharmaceutically acceptable salts, solvates and prodrugs thereof, wherein each R and R? pair are independently selected from (i) or (ii); (i) R and R? are independently selected from hydrogen, substituted or unsubstituted alkyl, substituted or unsubstituted alkenyl, substituted or unsubstituted alcohol, substituted or unsubstituted aryl, substituted or unsubstituted cycloalkyl, substituted or unsubstituted heterocyclic, and substituted or unsubstituted heteroaryl, or (ii) R and R? together form a substituted or unsubstituted heterocyclic ring structure, or a substituted or unsubstituted heteroaryl ring structure; X is hydrogen, or an alkyl; and Y is O or S.

Abstract: Methods and compositions for modulating repeat non-ATG protein (RAN protein) translation are provided. In some aspects, the disclosure provides methods of inhibiting RAN protein translation by contacting a cell with an effective amount of an inhibitor of eIF2 phosphorylation or an inhibitor of protein kinase R (PKR). In some embodiments, methods described by the disclosure are useful for treating diseases associated with RAN protein translation, such as certain neurodegenerative diseases.

Abstract: The present disclosure relates to a continuous process for impregnating active pharmaceutical ingredients (API) onto porous carriers, including the steps of introducing a porous carrier into a first feeder; continuously directing the porous carrier from the first feeder into a continuous blender, wherein the continuous blender comprises one or more nozzles; continuously introducing a solution comprising an API dissolved in solvent into the continuous blender through the one or more nozzles to form API-impregnated porous carrier; and continuously drying the API-impregnated porous carrier using a fluidized bed dryer to form a powder. The present disclosure also relates to a continuous process for manufacturing pharmaceutical drug products using continuously manufactured API-impregnated porous carriers. The present disclosure also relates to a continuous pharmaceutical drug manufacturing process that includes API-impregnated porous carriers as a raw material.

Abstract: Seminaphthofluorophore-selenium probes are disclosed. The probes include a seminaphthofluorophore scaffold substituted with at least one diselenide moiety having a formula —Y—C(Q)O—(CH2)m—Se—Se—(CH2)n—ORf, where Rf is hydrogen or C1-C3 alkyl, Q is O or S, Y is O or N(Rg) where Rg is H or alkyl, and m and n independently are integers. The probes may be used to detect presence of a thioredoxin reductase.

Abstract: The present invention provides a system for providing a T cell product, including a T cell master cell bank and/or a T cell working cell bank.

Abstract: A detection substrate of surface-enhanced Raman scattering including a substrate, pillar structures, and target-analyte linking substances are provided. The pillar structures are disposed on the substrate. The pillar structure has a Raman active surface. The ratio of a maximum length of the top-view pattern of the pillar structures to a gap between the adjacent pillar structures ranges from 0.2 to 0.4. The target-analyte linking substances are disposed on the pillar structures.

Abstract: Objects are to provide: a fusion protein capable of binding to lipid droplets while having an enzymatic activity to synthesize a hydrophobic compound; a method for producing a substance including accumulating a hydrophobic compound in lipid droplets using the fusion protein; a vector which can enhance production of a hydrophobic compound when it is introduced into cells using genetic recombination techniques; and a transgenic cell into which the vector or a gene coding for the fusion protein has been introduced. The present disclosure relates to a fusion protein having an amino acid sequence (first amino acid sequence) capable of binding to lipid droplets, and an amino acid sequence (second amino acid sequence) having an enzymatic activity to synthesize a hydrophobic compound, with the enzymatic activity of the second amino acid sequence being maintained.

Abstract: An apparatus for estimating lipid concentration is provided. According to an example embodiment, the apparatus may include a training data collector configured to collect, as training data, a reference lipid concentration measured through blood samples of a plurality of users for a predetermined time period and sensor data obtained through light signals detected from the plurality of users for the predetermined time period and a processor configured to perform preprocessing including a moving average and data augmentation on the obtained sensor data, select a valid variable relevant to a change in lipid concentration based on the preprocessed sensor data and the reference lipid concentration, and generate a lipid concentration prediction model based on the selected valid variable.

Abstract: A system for automated comprehensive assessment of clinical lumbar MRIs includes a MRI standardization component that reads MRI data from raw lumbar MRI files, uses an artificial intelligence (AI) model to convert the raw MRI data into a standardized format. A core assessment component automatically generates MRI assessment results, including multi-tissue anatomical annotation, multi-pathology detection and multi-pathology progression prediction based on the structured MRI data package. The core assessment component contains a semantic segmentation module that utilizes a deep learning artificial intelligence (AI) model to generate an MRI assessment results that contains multi-tissue anatomical annotation, a pathology detection module to generate multi-pathology detection, and a pathology progression prediction module to generate multi-pathology progression prediction.

Abstract: Provided are organometallic compounds. Also provided are formulations comprising these organometallic compounds. Further provided are OLEDs and related consumer products that utilize these organometallic compounds.

Abstract: Disclosed is multi-modal few-shot learning device for user identification using a walking pattern based on deep learning ensemble. The device includes: a walking data collector configured to collect walking data of a user from a smart insole including any one or more of a pressure sensor, an acceleration sensor, and a gyro sensor; a preprocessor configured to convert a series of time series walking data obtained from each of the sensors included in the smart insole into a unit format data set; and an ensemble learner configured to apply an ensemble learning model that provides one final prediction by training CNN series learning and RNN series learning respectively and independently based on the unit-format data set generated by the preprocessor.

Abstract: Disclosed are a heterogeneous zeolite membrane and a method of preparing the same, and more particularly a heterogeneous zeolite membrane that has CHA and DDR zeolite structures by growing seed particles into a crystal structure different from that of the zeolite membrane and can thus separate CO2/N2 and CO2/CH4 even under wet conditions, a method of preparing the same, and a method of capturing and removing carbon dioxide using the membrane.