Abstract: Structures for a wavelength-division multiplexing filter and methods of forming a structure for a wavelength-division multiplexing filter. A waveguide core of the wavelength-division multiplexing filter includes a first bend having a first curvature and a second bend having a second curvature different than the first curvature. The structure further includes a waveguide core region having a first end surface, a second end surface, and a bend arranged between the first and second end surfaces. The bend is positioned over the first bend of the waveguide core in an overlapping relationship.
Type:
Grant
Filed:
March 16, 2021
Date of Patent:
January 10, 2023
Assignees:
GlobalFoundries U.S. Inc., Khalifa University of Science and Technology
Inventors:
Yusheng Bian, Michal Rakowski, Roderick A. Augur, Marios Papadovasilakis, Sujith Chandran, Jaime Viegas, Yonas Gebregiorgis
Abstract: An apparatus for network switching may include a plurality of input ports, a plurality of output ports, and a subset of pre-configured interconnection patterns including some but not all of the possible interconnection patterns between the input ports and the output ports. The apparatus may be communicatively coupled to a network via the input ports and/or the output ports. The apparatus may be configured to switch to a first interconnection pattern and a second interconnection pattern from the subset of pre-configured interconnection patterns. The first interconnection pattern and the second interconnection pattern may each provide a set of connections between the input ports and the output ports. At least one signal between the input ports and the output ports may be transmitted via the first interconnection pattern and/or the second interconnection pattern. Related methods are also provided.
Type:
Grant
Filed:
September 19, 2017
Date of Patent:
January 10, 2023
Assignee:
The Regents of the University of California
Inventors:
George Porter, Joseph Ford, Alex Snoeren, George Papen, William Mellette
Abstract: Systems and methods are configured to control operation of an HVAC system providing climate control for a zone of a structure. In various embodiments, a constrained optimization problem is performed to set control commands for controlling operation of the HVAC system to achieve one or more objectives while providing a supply air flow at an air temperature and a humidity ratio for the zone at a future time. For instance, the optimization problem may include a cost function having constraints based on a desired temperature setpoint and a humidity ratio for the zone. A value is set for each control command based on the performance of the constrained optimization problem to achieve at least one of the objectives and as a result, the supply air flow at the air temperature and humidity ratio is provided by the HVAC system at the future time to the zone based on the values.
Type:
Grant
Filed:
July 16, 2020
Date of Patent:
January 10, 2023
Assignee:
University of Florida Research Foundation, Incorporated
Abstract: A mosquito surveillance device includes one or more mosquito traps having a camera capable of taking images of mosquitos and transmitting the images electronically to a receiver. Suitable traps include an ovitrap, for example. Images may be transmitted from inside or outside the trap to a receiver using low bandwidth cellular phone networks. The images are processed and displayed using software forming mosquito data. The images may be analyzed and the number of live mosquitos identified, the number of dead mosquitos identified, the species of mosquitos identified, or mapped vector densities in real time identified preferably at high resolution.
Type:
Grant
Filed:
January 26, 2018
Date of Patent:
January 10, 2023
Assignee:
The Johns Hopkins University
Inventors:
Soumyadipta Acharya, William Patterson, Margaret Glancey, Nicholas Radant, Justin Chang, Kimberly Ashman
Abstract: The present invention provides compositions of CD180 targeting molecules coupled to heterologous antigens, and their use in treating and/or limiting disease.
Abstract: An atomic force microscope includes a cantilever operating in amplitude modulation mode. A controller determines the amplitude of the cantilever oscillation by processing a signal representative of the cantilever motion by square-rooting a signal having a value substantially equal to a sum of a square of the received signal and a squared and phase-shifted version of the received signal. The aforementioned processing, in some implementations is implemented using analog circuit components.
Abstract: A lamina emergent torsional (LET) joint that includes an integrated membrane to reduce, or eliminate, certain unwanted motions and/or displacements associated with the operation of the LET joint is disclosed. The membrane-integrated LET joint (i.e., M-LET) can be used as a hinge for a lamina emergent mechanism and/or as a surrogate fold for an origami application to ensure accurate and repeatable transitions from a planar (i.e., lamina) state to a non-planar (i.e., lamina-emergent) state, and vice versa.
Type:
Grant
Filed:
January 2, 2019
Date of Patent:
January 10, 2023
Assignee:
Brigham Young University (BYU)
Inventors:
Guimin Chen, Larry Howell, Spencer Magleby
Abstract: The present disclosure provides an electroplating method, comprising providing an electroplating solution, wherein the electroplating solution includes an effective microorganisms aqueous solution and metal chloride; disposing a workpiece, wherein at least a part of the workpiece is in contact with the electroplating solution; and performing an electroplating process to electroplate metal of the metal chloride onto the workpiece.
Abstract: Disclosed cannula systems can detect the tissue type within which the cannula tip is located in real time using electrodes adjacent the cannula tip. The sensing cannula system can differentiate when the cannula tip is in adipose tissue or muscle based on electrical impedance. The system can be used in fat grafting and liposuction procedures, for example. An operator can detect if the cannula tip enters muscle by watching for an indicator light or audible alarm that is automatically activated by the device based on a change in sensed impedance. The device may also stop the flow of fat through a pump halting injection into the sub-muscular space.
Type:
Grant
Filed:
May 10, 2019
Date of Patent:
January 10, 2023
Assignees:
University of Pittsburgh—Of the Commonwealth System of Higher Education, UPMC
Inventors:
David Turer, William W. Clark, April Lawrence, Ehsan Qaium, Joseph P. Rubin, Cameron Dezfulian
Abstract: This invention provides highly attenuated influenza viruses and vaccines. The attenuated viruses and vaccines proliferate well and have high safety factors. The attenuated viruses providing protective immunity from challenge by virus of the same subtype, as well as cross protection against heterologous viruses.
Type:
Grant
Filed:
June 10, 2019
Date of Patent:
January 10, 2023
Assignee:
The Research Foundation for State University of New York
Inventors:
Steffen Mueller, Eckard Wimmer, Bruce Futcher, Steven Skiena, Chen Yang
Abstract: Compounds and methods for inhibiting cofilin activity or reducing total cofilin, improving motor deficits, attenuating LPS-induced microglial activation and inflammation, reducing microglial migration and proliferation, reducing TNF-?, reducing NF-?B, and improving motor deficits in a subject are described.
Type:
Grant
Filed:
May 5, 2020
Date of Patent:
January 10, 2023
Assignee:
The University of Toledo
Inventors:
Saleh Alaqel, Viranga Tillekeratne, Zahoor A. Shah
Abstract: The disclosure provides a composition for suppressing inflammation comprising at least one substance that disrupts a stem-loop structure in the 3? untranslated region of a Regnase-1 mRNA, wherein the stem-loop structure is at least one stem-loop structure selected from a first stem-loop structure formed in a region corresponding to positions 231 to 245 of SEQ ID NO: 1 and a second stem-loop structure formed in a region corresponding to positions 424 to 442 of SEQ ID NO: 1.
Abstract: Phosphatidylinositol 3-kinases (PI3Ks) are known to be important regulators of signaling pathways. To determine whether PI3Ks are genetically altered in cancers, we analyzed the sequences of the PI3K gene family and discovered that one family member, PIK3CA, is frequently mutated in cancers of the colon and other organs. The majority of mutations clustered near two positions within the PI3K helical or kinase domains. PIK3CA represents one of the most highly mutated oncogenes yet identified in human cancers and is useful as a diagnostic and therapeutic target.
Type:
Grant
Filed:
October 7, 2019
Date of Patent:
January 10, 2023
Assignee:
The Johns Hopkins University
Inventors:
Yardena Samuels, Victor E. Velculescu, Kenneth W. Kinzler, Bert Vogelstein
Abstract: A reference electrode includes a metal body, a lead disposed within the metal body, an insulator disposed between the lead and the metal body, the insulator including a ceramic material, and a porous metal chamber coupled to the metal body, the lead extending into the porous metal chamber. The porous metal chamber is configured to maintain an electrolyte solution within the porous metal chamber to establish a redox couple with the lead.
Type:
Grant
Filed:
February 22, 2021
Date of Patent:
January 10, 2023
Assignee:
The Regents of the University of Michigan
Abstract: An optoelectronic device grown on a miscut of GaN, wherein the miscut comprises a semi-polar GaN crystal plane (of the GaN) miscut x degrees from an m-plane of the GaN and in a c-direction of the GaN, where ?15<x<?1 and 1<x<15 degrees.
Type:
Grant
Filed:
January 26, 2018
Date of Patent:
January 10, 2023
Assignee:
The Regents of the University of California
Inventors:
Po Shan Hsu, Kathryn M. Kelchner, Robert M. Farrell, Daniel A. Haeger, Hiroaki Ohta, Anurag Tyagi, Shuji Nakamura, Steven P. DenBaars, James S. Speck
Abstract: A control system of a vehicle includes: a target speed module configured to, using a parametric driver model and based on first driver parameters, second driver parameters, and vehicle parameters, determine a target vehicle speed trajectory for a future predetermined period; a driver parameters module configured to determine the first driver parameters based on conditions within a predetermined distance in front of the vehicle; and a control module configured to adjust at least one actuator of the vehicle based on the target vehicle speed trajectory and a present vehicle speed.
Type:
Grant
Filed:
May 27, 2020
Date of Patent:
January 10, 2023
Assignees:
GM GLOBAL TECHNOLOGY OPERATIONS LLC, Carnegie Mellon University
Abstract: The present invention discloses a novel nano-composite antibacterial material and a preparation method and an application thereof, and belongs to the technical field of preservative materials. The novel nano-composite antibacterial material disclosed by the present invention is prepared by mixing a dimethylimidazole solution, deionized water and a zinc nitrate solution to prepare a metal-organic framework carrier, compositing with nisin to form a nano antibacterial composite material, separating out from a solution in a precipitate form, centrifuging, removing a supernatant, cleaning and re-suspending with the deionized water. The novel nano-composite antibacterial material prepared by the present invention has an antibacterial effect superior to nisin having a same concentration.
Type:
Grant
Filed:
March 12, 2020
Date of Patent:
January 10, 2023
Assignee:
Tianjin University of Science and Technology
Abstract: Compositions and methods for inhibiting brain tumor proliferation, or for inhibiting or halting TM formation, invasion, and/or proliferation, or for rendering brain tumor cells sensitive to chemotherapy or radiation, or for treating a brain tumor, or for inducing cell death, involving mDia agonists such as IMM01 and IMM02, are described.
Type:
Grant
Filed:
March 10, 2020
Date of Patent:
January 10, 2023
Assignee:
The University of Toledo
Inventors:
Kathryn Eisenmann, Krista M. Pettee, Kathryn Becker
Abstract: A physical environment is equipped with a plurality of sensors (e.g., motion sensors). As individuals perform various activities within the physical environment, sensor readings are received from one or more of the sensors. Based on the sensor readings, activities being performed by the individuals are recognized and the sensor data is labeled based on the recognized activities. Future activity occurrences are predicted based on the labeled sensor data. Activity prompts may be generated and/or facility automation may be performed for one or more future activity occurrences.
Type:
Grant
Filed:
September 26, 2019
Date of Patent:
January 10, 2023
Assignee:
Washington State University
Inventors:
Diane J. Cook, Bryan Minor, Janardhan Rao Doppa